CI01000051_07391277_07399712 (ABCB11B, ABCB11)


Basic Information

Item Value
gene id CI01000051_07391277_07399712
gene name ABCB11B, ABCB11
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000051
NCBI id null
chromosome length 8436717
location 7390634 ~ 7399786 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000051_07391277_07399712.mRNA
ATTTAAAAAAAGTTTCTGTTTATTTTTAGGTTTAAATTAGATTTAAACCCCATTTTATACTACCCTTCAAGAGTTTAGGGCAAGTTTTTTTTTTTTTTTTTTTAAGAAATTAATACTTTTATTTAGGACAAAAAGACATTTATAATGTTACAAAAGATTCCTATTTCAAATAAATGCAGTTTTTTTCTATTCATCAAAGAATCCTAAAAAAAGAGCAAGTTTATACAAAAATTTTAAGCAGCACAACTGTATTTAACACTAACAACAATAAGAAATTATTCTTATTGTTATCAGCATATTAGAATGATTTTTAAAGGATCATGTGACACTGAAGACTGGAGTAATGATGCTGAAAACGAAAATTCAGCTTTGCCATCACAGTAATAAATTACATTTTAATATATTTATAAAAATATAAAGCAGTTATTTTAAATTGTAATGATAATTGACAACATTATTGTTTTTTGATCAAATAAATGCAGCATTGGTTAGCATGAGAGACTTCTTTCAAAAACATGAAAAATCTTACTGACTCCAGACTTTTGAACAGTATTGTATAATATGTATATAGTATGTTTCTTAAACATTTTTAACCTTTTCTTTTTAGAAATTTGACACTTTGGTAGGTGAGGGTGGTGGCCAGATGAGTGGCGGACAGAAACAGAGAATCGCAATAGCCCGGGCACTTGTGAGGAATCCCAGAATCCTTCTGCTGGACATGGCTACATCAGCTCTGGACAATGAGAGTGAAGCTGTTGTACAGGAGGCTTTGGACAAGGTACGATTGGGTCGCACCACCATCTCCATAGCTCACCGTTTATCTACAATAAAGAATGCAGATGTGATCGTGGGATTCGAGCATGGCCGTGCCGTGGAACGAGGAAAACATGATGAGCTGCTGGATAGAAAGGGCGTCTACTTCACGTTGGTCACTCTTCAGAGCCAGGGAGACAAAGCCCTCAATCAAAAAGCCAAACAGGAGATGGAGGAAGCTGAAAGTATTGATCTTGATGCAGAGAGAAAGAGTCTCAGCAGGGCAGGAAGTTATCGTGCTAGCTTGAGGGCTTCTGTTCGCCAAAGATCACGATCACACCTGTCGAATGTTGTACCCGAATCCTCTGTGGCCTTTGCTGGAGAGCTAGGCCCTCGCTCATACTCTGAAACCTGCGTTCCTCAAGGGATCAAGGGAAAGAGCAGCCTTCCTGATGATGATTCAGAGGTGGTGGAACCAGCTCCAGTGGCTCGTATTCTGAAATATAACGCTCCTGAATGGCCCTACATGCTCTTTGGAAGTTTTGGAGCAGCTGTGAATGGAGGGGTGAACCCAGTCTACTCTCTCCTCTTCAGCCAAATCCTGGCGACATTCTCGATGCCTGATCCTGTTGAACAACGGAGGGAAATTAATGGCATCTGTCTGTTCTTTGTAGTTGTTGGTTTGGTTTCATTTTTCACACAAATGTTACAGGGCTATGCATTCTCTAAATCTGGGGAGCTGCTGACACGTAGACTGAGGCGTCTGGGTTTTCGGGCAATGTTGGGGCAGGAGATCGGCTGGTTTGATGACCACAAAAACAGCCCAGGTGCTTTGACCACAAGACTGGCCACCGATGCCTCACAAGTCCAGGGAGCCACAGGTTCTCAGATAGGCATGATCGTGAATTCTCTGACCAACATTGGTGTGGCCATTATCATCTCCTTCTACTTCAGCTGGAAGCTCACTATGGTCATCCTGTGCTTCCTGCCCTTCTTGGCTCTCTCTGGAGGGTTTCAGGCTAAGATGCTAACCGGATTTGCCAAGCAGGACAAAGAGGCCATGGAGGCAGCAGGACGGATATCTGGAGAAGCTCTGAATAACATCCGCACCATTGCCGGCCTAGGAAAAGAGCGTAATTTTGTGGAAATGTTCGACACACAGTTGGAGGCCCCGTATCATGCAGCGCTGAAGAAGGCTAATGTTTACGGTGCCTGCTATGGGTTTTCTCAGTGTGTGGTTTTCATGGCAAACTCCGCCTCTTATCGATTTGGTGGATACCTGGTCTATCGAGAGGGGCTACACTTTAGTATGGTTTTCAGGGTGATTTCAGCGATTGTAACCAGCGGTACAGCTCTCGGCCGAGCGTCCTCCTACACTCCAGATTACGCCAAAGCCAAGATCTCTGCCGCACGATTCTTTGAGCTACTCGACCGCATTCCCAAAATTAGCGTCTATAGCAATGAAGGAGACAAATGGGATAATTTTAAAGGGGATATTGAGTTTATAGACTGCAAGTTCACATACCCATCCCGGCCAGATATTCAGGTTCTGAATGGTCTGAATGTGAGTGTTAAGCCGGGACAGACTTTGGCCTTTGTGGGCAGCAGTGGCTGTGGCAAGAGCACTAGCGTTCAACTATTGGAGAGGTTCTATGATCCTAACAATGGACGTGTGCTCATTGATGGCCGTGAATCTACTCGGGTCAACGTTGCTTTCCTGCGCTCTAAGATTGGGATTGTCTCTCAGGAGCCAATTTTGTTTGACTGCAGTATTGCAGAGAACATCCGCTATGGAGACAATCAACGAGAGCTCAGCATGGATGATGTCATCTCCGCAGCCAAGAAGGCCCAGCTGCATGACTTTGTCATGTCACTTCCTGAGAAATACGACACTAATGTTGGTTCCCAAGGTTCACAGCTTTCCCGGGGTCAAAAGCAACGCATTGCTATAGCCAGAGCGATCATAAGAGATCCCAAAATACTTCTACTGGATGAAGCCACCTCAGCACTGGACACAGAAAGTGAGAAGACTGTACAGGAGGCTTTGGATAAAGCGAGGGAAGGCAGAACTTGTATCGTCATTGCTCACCGTCTGTCTACTATCCAGAACTCTGACATCATAGCTGTGATGTCTAGGGGATATGTAATTGAGAAGGGCACACACGACTATCTCATGGGCCTGAAGGGGGCGTACTACAAACTCGTCACAACCGGAGCTCCAATCAGCTAATCTCTCAATCAGCACATAAGAGAACTGGACAGGATTTCATACATCCTTCTAGTGACAGATAGATGAATATAATA

Function

symbol description
abcb11b Predicted to enable ABC-type bile acid transporter activity and canalicular bile acid transmembrane transporter activity. Acts upstream of or within bile acid secretion. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in liver. Used to study progressive familial intrahepatic cholestasis 2. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).
abcb11 Enables ABC-type bile acid transporter activity; ABC-type xenobiotic transporter activity; and canalicular bile acid transmembrane transporter activity. Involved in several processes, including canalicular bile acid transport; drug export; and drug transmembrane transport. Located in apical plasma membrane and cell surface. Implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2.

NR:

description
sister of P-glycoprotein, partial

GO:

id name namespace
GO:0042626 ATPase-coupled transmembrane transporter activity molecular_function

KEGG:

id description
K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000051_07391277_07399712.mRNA True 3057 mRNA 0.44 14 7390634 7399786

Neighbor

gene id symbol gene type direction distance location
CI01000051_07378590_07389158 ABCB11B, ABCB11 coding upstream 1064 7378590 ~ 7389570 (+)
CI01000051_07367270_07370738 ATP5B coding upstream 19756 7366852 ~ 7370878 (+)
CI01000051_07345863_07353841 MKNK1 coding upstream 35514 7345863 ~ 7355120 (+)
CI01000051_07337005_07340657 MOB3C, MOB3C.S, MOBKL2C coding upstream 49942 7336853 ~ 7340692 (+)
CI01000051_07287140_07287867 NA coding upstream 102599 7287140 ~ 7288035 (+)
CI01000051_07470914_07489207 LRP1AB, LRP1 coding downstream 71128 7470914 ~ 7489242 (+)
CI01000051_07507549_07530087 HOMER3 coding downstream 107763 7507549 ~ 7530087 (+)
CI01000051_07534938_07540104 NA coding downstream 132853 7532639 ~ 7540418 (+)
CI01000051_07542167_07549737 ARRDC2 coding downstream 142381 7542167 ~ 7550660 (+)
CI01000051_07611022_07612093 NA coding downstream 210663 7610449 ~ 7612093 (+)
G221393 NA non-coding upstream 14429 7375973 ~ 7376205 (+)
G221385 NA non-coding upstream 16900 7373383 ~ 7373734 (+)
G221378 NA non-coding upstream 58766 7331657 ~ 7331868 (+)
G221311 NA non-coding upstream 96881 7292239 ~ 7293753 (+)
G221347 NA non-coding upstream 103979 7286387 ~ 7286655 (+)
G221386 NA non-coding downstream 1389 7401175 ~ 7413007 (+)
G221336 NA non-coding downstream 23137 7422923 ~ 7425419 (+)
G221406 NA non-coding downstream 50693 7450479 ~ 7450890 (+)
G221408 NA non-coding downstream 51954 7451740 ~ 7452011 (+)
G221409 NA non-coding downstream 55545 7455331 ~ 7455537 (+)
G221319 NA other upstream 48088 7342041 ~ 7342546 (+)
CI01000051_06825895_06830637 NA other upstream 557566 6825895 ~ 6830637 (+)
G219803 NA other upstream 2338601 4914974 ~ 5052033 (+)
CI01000051_04374052_04393328 NA other upstream 3015304 4372658 ~ 4393677 (+)
G218981 NA other upstream 4143761 3245443 ~ 3246873 (+)
CI01000051_08211233_08214513 NA other downstream 705857 8209722 ~ 8214696 (+)
G222727 NA other downstream 943156 8342942 ~ 8343448 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location