CI01000053_05593016_05597420 (ORAI1, ORAI1A)


Basic Information

Item Value
gene id CI01000053_05593016_05597420
gene name ORAI1, ORAI1A
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000053
NCBI id null
chromosome length 7014373
location 5593016 ~ 5597488 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000053_05593016_05597420.mRNA
ATGAGTTCTAACGAGCACTCCCTTCAAGCTTTGTCATGGAGAAAACTTTACTTGAGCCGAGCTAAGCTTAAAGCGACCAGCAGAACCTCTGCCCTGCTCTCCGGCTTTGCTATGGTAGCAATGGTGGAAGTGCAGTTGGAGGAAGATCACAATTACCCTCCTGGTTTATTGGTTGCTTTCAGTGCCTGCACAACAGTGCTGGTGGCCGTCCATCTCTTTGCCTTGATGATCAGCACATGTATCCTGCCCAACCTGGAAGCCGTGAGCAACGTCCACAACCTCAACTCCATAAGGGAATCGCCACATGAGCGGATGCACCGTCACATCGAGCTGGCCTGGGCCTTCTCCACCGTCATAGGCACCCTTCTGTTTCTCGCAGAGGTGGTTCTTCTCTGCTGGGTCAAGTTCCTTCCTCTGAAGAATAAAATCCCTGCCAAGCAAGAGAATGTAACTCAGCCTGAAGGTATAAGCCCGGGGGAAGCCGCGGCAATCGCTTCTACCTCCATCATGGTGCCCTTTGGCTTGGTGTTTATTGTTTTCGCTGTGCATTTTTACCGTTCGCTGGTCAGCCACAAAACAGAGCGGCAGAATGAGGAGTTGGAGGTTCTGGCCAAAATCACTCAGATGCAAAACCAACTGGATAACAGGGGAGAGGCGAATTTTGCTTAGCCTACGCACTTATATGAGTCCTTGTTCTCACACCAAACACTTTCCCAAAATATGGAATGTTGTCACAA

Function

symbol description
orai1a Predicted to enable store-operated calcium channel activity. Predicted to be involved in store-operated calcium entry. Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Human ortholog(s) of this gene implicated in immunodeficiency 9 and tubular aggregate myopathy 2. Orthologous to human ORAI1 (ORAI calcium release-activated calcium modulator 1).
orai1 Enables identical protein binding activity and store-operated calcium channel activity. Involved in calcium ion transport; positive regulation of adenylate cyclase activity; and positive regulation of calcium ion transport. Located in cytosol and plasma membrane raft. Is integral component of plasma membrane. Implicated in immunodeficiency 9 and tubular aggregate myopathy 2.

GO:

id name namespace
GO:0015279 store-operated calcium channel activity molecular_function

KEGG:

id description
K16056 ORAI1; calcium release-activated calcium channel protein 1

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000053_05593016_05597420.mRNA True 737 mRNA 0.50 2 5593016 5597488

Neighbor

gene id symbol gene type direction distance location
CI01000053_05589379_05590208 NA coding upstream 1914 5588892 ~ 5591102 (+)
CI01000053_05563771_05573792 RNF34, RNF34A coding upstream 19051 5563771 ~ 5573965 (+)
CI01000053_05526931_05550454 NA coding upstream 42544 5526629 ~ 5550472 (+)
CI01000053_05471449_05512831 LRRC75B coding upstream 79960 5471449 ~ 5513074 (+)
CI01000053_05435608_05443587 GGT5A coding upstream 147790 5435479 ~ 5445226 (+)
CI01000053_05704944_05710574 GCK, GK coding downstream 107360 5704848 ~ 5711121 (+)
CI01000053_05764395_05769061 NA coding downstream 166907 5764395 ~ 5769085 (+)
CI01000053_05784784_05786704 DUSP2 coding downstream 186778 5784266 ~ 5787658 (+)
CI01000053_05796556_05798076 ADRA2B coding downstream 198385 5795873 ~ 5799824 (+)
CI01000053_05818799_05861616 NA coding downstream 221311 5818799 ~ 5861872 (+)
G228337 NA non-coding upstream 40593 5551999 ~ 5552423 (+)
G228374 NA non-coding upstream 50477 5542258 ~ 5542539 (+)
G228334 NA non-coding upstream 68805 5523580 ~ 5524211 (+)
G228392 NA non-coding downstream 7295 5604783 ~ 5605652 (+)
G228394 NA non-coding downstream 11805 5609293 ~ 5609517 (+)
G228406 NA non-coding downstream 45989 5643477 ~ 5643811 (+)
G228414 NA non-coding downstream 65544 5663032 ~ 5663257 (+)
G228369 NA non-coding downstream 94038 5691526 ~ 5696553 (+)
G228257 NA other upstream 214567 5375553 ~ 5378449 (+)
G227317 NA other upstream 1177423 4414951 ~ 4415593 (+)
G226399 NA other upstream 1895487 3620798 ~ 3697529 (+)
G226347 NA other upstream 2318105 3272374 ~ 3274911 (+)
CI01000053_06725452_06758944 NA other downstream 1125711 6725452 ~ 6758944 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00018759 orai1,LOC106585507,LOC108232614,LOC106568227,LOC105014888 coding CM030135.1 CM030135.1 19959738 ~ 19966779 (+)