XLOC_009861 (gsdmeb)


Basic Information

Item Value
gene id XLOC_009861
gene name gsdmeb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 21425114 ~ 21441226 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019676
ACAACATAGAAGTAGCCGCGCTTCGACGATGTCTTGCTGCCTGGGCTTTTGTTTATAAGTGTGTCTACAGTCAAACAACCACGAGAAAAGACCACGctGATCCTCAAAAGTCTTCTTGTCAGCATTGAAGATGTTTGCAAAAGCCACTAAGAACCTGCTCTCTGAGATAGACTCTGAAGGTTTCCTGATCCCAGTGTTGTGCCTGAATGACTCAGATGGTCTTAGTCCTCAGGCGCTGGTCATCAAGCGTAACCGATACTGGTTTTGGCAGCAACCCAAATACAAGCCAACAGACTTCAAACTGAGTGATGTTCTAGTTGGAGATCCCATAAATCCAGTTGTGGTTGAAACTGAATTTTTGACCTATAAAGGCAAAGTTATGGATACTAAAAGTGGAAGTGCTGTAGCAGAACTTGGGCCAGGGACCATTAATATAGGTGGCTCCGGATCCAGCAAACTGCAGTCATCATTTGGAAACTTAAAGAAACAGGAGCTGGATTTGCAGAAGCTCTTACATGATTCCAAATCCAGAGTTCTAGACATGCAGCACTCTCTGATCCAGCAGACACGGAACGCAAAGACGGAGGTGTTGGCGGTAGTGAAGGAACGAATCATTACCACTCAGCCCTGCACCATCACTGAGGAGGTTCAGGAAGGTGGTTCCTGCACTGGAATGTTTGGGTTCAATAAGACAATAAAGGTTTCATCTAATGATAAAGGAAAGCCTTCAATTGCGTACGACACTGATGTGTCTATCGACATCCCCCCCAAAACCACCCTTGCTTACAGCGTGATTGAATTAGACATTGCTCACACAGGACACTATGAACTGTGTCTGCTGCCAGCAGTCAAAGGTGGATTTGAAATTGATGGCCCAGTCAAGGTGAAACAAGCAGTCACAGTTAGTGCTGCACCAGGGAATCCAACCCACAACATGCAGAAAGAACTTGTAGGACTCGAAGGCCAGTTTAAAGTTCTGTCTAAACTGCCGTCTAGCACACGCTTCTCGTTATTCCAGCAGATCTCTCTACTCCTGCAGAACAGCGCAGTCATTAGCATTTTGGGGAGCACACTAGAGGACCTGTGTGGAGGGACACAGCCTGATCCCAGTACATTAGCCGAGGTGCCTGAACTGAAGGTTACACTGGAGCTCATACAGAAAAGTGCTGGTAAAAAACCCTCTGGACAACATCAGAAGCAAAGCACACTTACTGCCACACACCTGCTCATCAGTGCTCTAGACGAGATGAGTAAGCCAGCACTCTTCCTGCTCAAATCCTGCTGCAGTTACACAACCCTGCAAGCTCTGCTCCATCTTGTGCAGAATATGGCTTTAAATGAGAAATCCTCTCTGAAAGACGCTGCTCTGGATGTTTTAGCCGATGAGGTGGTTTTCAAAAACATTACATCACTCTTTAATTCCTGCAACGTGATGCTGCTCAAGGATGACAATTCACTTATTACAAAAATCAGCAACCCAGAAGATCGTCTTCCCCTCATGTTGTGCATTGCAGTCAAGGGTTTGGCTTCTCTTGCACCCCATGTTTGATAATCTGTTGTAACTTATGAAGACCAAAGGCCCCAAGAAGTTTCTCACTGCAGCCTGCAGTGGACATCCATCCCCACCAACATCCAAGTGTAAGCCACTGCTGCCTCACTGTAGACTACAGCATGATGACAAACTAGAACAAGTCCAATATGTAATGGACATGTATTtgtgatgggttgtagctagaaataagaattatttgtatttataaaattaCCCATTACAATGTGTGCTGTTATGCCTACACCTACCCCAAAGTTAAATTCAACCCTAACAGTTAAGCATGCGCATTACAATGCCCAATGTGACACTTGGATGAGTGCAGGGTTGCATGTCTACTGCTTGCTGCAGCGAGACCTACTTGAAGGTCCCCAAAGCCTGCAGGTGGACAATCTACAAACTGGGAAAGAAACAATAACAATCAAGCCCTACATTGCCTTAAAGCCCGAGTAATACTTTTGCCTTGCGACGCATCgtgcacctccgctgactgcTCATGCGCCTCACGAAacagacgaggcttttatacttgacgcgtttgccgttgtgatatttttttaaatgacagggggcagtcaaaagaaacccactgtAAAATCAGACAGATAACCATAAAAGTAGGAAGTTTCTGGAACTACgtcatattattatcatcattccaGATTTTTTAAGCACTTCTTTAATAAAGTATTTGAATGattgatttataaatatttcaccatttaagattttttttttaaatcgaacTGATGCATCACATGCTTTGGTTTATATCTCAGACAGTTTtgcctattaaagtttattaaaatattactgacAA
>TCONS_00019677
ACGATGTCTTGCTGCCTGGGCTTTTGTTTATAAGTGTGTCTACAGTCAAACAACCACGAGAAAAGACCACGGTAAGCACGAGctGATCCTCAAAAGTCTTCTTGTCAGCATTGAAGATGTTTGCAAAAGCCACTAAGAACCTGCTCTCTGAGATAGACTCTGAAGGTTTCCTGATCCCAGTGTTGTGCCTGAATGACTCAGATGGTCTTAGTCCTCAGGCGCTGGTCATCAAGCGTAACCGATACTGGTTTTGGCAGCAACCCAAATACAAGCCAACAGACTTCAAACTGAGTGATGTTCTAGTTGGAGATCCCATAAATCCAGTTGTGGTTGAAACTGAATTTTTGACCTATAAAGGCAAAGTTATGGATACTAAAAGTGGAAGTGCTGTAGCAGAACTTGGGCCAGGGACCATTAATATAGGTGGCTCCGGA
>TCONS_00019678
ccagctGATCCTCAAAAGTCTTCTTGTCAGCATTGAAGATGTTTGCAAAAGCCACTAAGAACCTGCTCTCTGAGATAGACTCTGAAGGTTTCCTGATCCCAGTGTTGTGCCTGAATGACTCAGATGGTCTTAGTCCTCAGGCGCTGGTCATCAAGCGTAACCGATACTGGTTTTGGCAGCAACCCAAATACAAGCCAACAGACTTCAAACTGAGTGATGTTCTAGTTGGAGATCCCATAAATCCAGTTGTGGTTGAAACTGAATTTTTGACCTATAAAGGCAAAGTTATGGATACTAAAAGTGGAAGTGCTGTAGCAGAACTTGGGCCAGGGACCATTAATATAGGTGGCTCCGGATCCAGCAAACTGCAGTCATCATTTGGAAACTTAAAGAAACAGGAGCTGGATTTGCAGAAGCTCTTACATGATTCCAAATCCAGAGTTCTAGACATGCAGCACTCTCTGATCCAGCAGACACGGAACGCAAAGACGGAGGTGTTGGCGGTAGTGAAGGAACGAATCATTACCACTCAGCCCTGCACCATCACTGAGGAGGTTCAGGAAGGTGGTTCCTGCACTGGAATGTTTGGGTTCAATAAGACAATAAAGGTTTCATCTAATGATAAAGGAAAGCCTTCAATTGCGTACGACACTGATGTGTCTATCGACATCCCCCCCAAAACCACCCTTGCTTACAGCGTGATTGAATTAGACATTGCTCACACAGGACACTATGAACTGTGTCTGCTGCCAGCAGTCAAAGGTGGATTTGAAATTGATGGCCCAGTCAAGGTGAAACAAGCAGTCACAGTTAGTGCTGCACCAGGGAATCCAACCCACAACATGCAGAAAGAACTTGTAGGACTCGAAGGCCAGTTTAAAGTTCTGTCTAAACTGCCGTCTAGCACACGCTTCTCGTTATTCCAGCAGATCTCTCTACTCCTGCAGAACAGCGCAGTCATTAGCATTTTGGGGAGCACACTAGAGGACCTGTGTGGAGGGACACAGCCTGATCCCAGTACATTAGCCGAGGTGCCTGAACTGAAGGTTACACTGGAGCTCATACAGAAAAGTGCTGGTAAAAAACCCTCTGGACAACATCAGAAGCAAAGCACACTTACTGCCACACACCTGCTCATCAGTGCTCTAGACGAGATGAGTAAGCCAGCACTCTTCCTGCTCAAATCCTGCTGCAGTTACACAACCCTGCAAGCTCTGCTCCATCTTGTGCAGAATATGGCTTTAAATGAGAAATCCTCTCTGAAAGACGCTGCTCTGGATGTTTTAGCCGATGAGGTGGTTTTCAAAAACATTACATCACTCTTTAATTCCTGCAACGTGATGCTGCTCAAGGATGACAATTCACTTATTACAAAAATCAGCAACCCAGAAGATCGTCTTCCCCTCATGTTGTGCATTGCAGTCAAGGGTTTGGCTTCTCTTGCACCCCATGTTTGATAATCTGTTGTAACTTATGAAGACCAAAGGCCCCAAGAAGTTTCTCACTGCAGCCTGCAGTGGACATCCATCCCCACCAACATCCAAGTGTAAGCCACTGCTGCCTCACTGTAGACTACAGCATGATGACAAACTAGAACAAGTCCAATATGTAATGGACATGTATTtgtgatgggttgtagctagaaataagaattatttgtatttataaaattaCCCATTACAATGTGTGCTGTTATGCCTACACCTACCCCAAAGTTAAATTCAACCCTAACAGTTAAGCATGCGCATTACAATGCCCAATGTGACACTTGGATGAGTGCAGGGTTGCATGTCTACTGCTTGCTGCAGCGAGACCTACTTGAAGGTCCCCAAAGCCTGCAGGTGGACAATCTACAAACTGGGAAAGAAACAATAACAATCAAGCCCTACATTGCCTTAAAGCCCGAGTAATACTTTTGCCTTGCGACGCATCgtgcacctccgctgactgcTCATGCGCCTCACGAAacagacgagg

Function

symbol description
gsdmeb Acts upstream of or within inner ear morphogenesis and regulation of biosynthetic process. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; heart tube; hematopoietic system; nervous system; and otic vesicle. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E).

GO:

id name namespace
GO:0042471 ear morphogenesis biological_process
GO:0042472 inner ear morphogenesis biological_process
GO:0009889 regulation of biosynthetic process biological_process
GO:0008219 cell death biological_process

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-7662 Acts upstream of or within inner ear morphogenesis and regulation of biosynthetic process. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; heart tube; hematopoietic system; nervous system; and otic vesicle. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E).

Ensembl:

ensembl_id ENSDARG00000040485

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019676 False 2369 mRNA 0.44 10 21425114 21441226
TCONS_00019677 False 434 mRNA 0.45 3 21425139 21429214
TCONS_00019678 True 1977 mRNA 0.46 9 21426524 21440926

Neighbor

gene id symbol gene type direction distance location
XLOC_009860 osbpl3b coding upstream 6339 21242491 ~ 21418775 (+)
XLOC_009859 NA coding upstream 282598 21141048 ~ 21142516 (+)
XLOC_009858 BX571678.1 coding upstream 369978 21016820 ~ 21055136 (+)
XLOC_009857 skap2 coding upstream 447408 20934353 ~ 20977706 (+)
XLOC_009856 hoxa2b coding upstream 495931 20926673 ~ 20929183 (+)
XLOC_009862 NA coding downstream 193161 21634387 ~ 21634836 (+)
XLOC_009863 si:ch211-154o6.3 coding downstream 257754 21698980 ~ 21745336 (+)
XLOC_009864 trim108 coding downstream 348477 21789703 ~ 21805974 (+)
XLOC_009865 zmp:0000000608 coding downstream 425935 21867161 ~ 21867872 (+)
XLOC_009866 NA coding downstream 433169 21874395 ~ 21877421 (+)
XLOC_009854 mir196d non-coding upstream 511630 20913413 ~ 20913484 (+)
XLOC_009848 NA non-coding upstream 729597 20684940 ~ 20695517 (+)
XLOC_009847 NA non-coding upstream 893342 20530125 ~ 20531772 (+)
XLOC_009840 CU855688.1 non-coding upstream 1615997 19805021 ~ 19809117 (+)
XLOC_009868 NA non-coding downstream 581065 22022291 ~ 22113936 (+)
XLOC_009869 NA non-coding downstream 882540 22323766 ~ 22327502 (+)
XLOC_009870 NA non-coding downstream 886744 22327970 ~ 22329028 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_08553934_08565167 DFNA5 coding CI01000016 null 8552843 ~ 8565246 (+)
mexican tetra (Astyanax mexicanus) G90502 NA non-coding NC_035906.1 CM008309.1 13002722 ~ 13016527 (+)