XLOC_009887 (adar)


Basic Information

Item Value
gene id XLOC_009887
gene name adar
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 23531583 ~ 23557714 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019725
TCATTGTCATTCAGCAGCGTTGTGTTTTCTATCTGCATGTGGCCTCTGGCAGGGACGCGGCTGGATTGTGCTCGTCGTCTGCGTATAAAAACCTGTCTTTGATACTGTCGTGATATTGCAACCAGACAGCTGAGATTCATCCTAATACGTACACAACTTCACTAAGCCTAACGCTACACCCTCCTCAGCCCCCACCCCTGCGCTATGAGCAGAGGTAGAGGAGGGAATTACAAAGATAGCCAGCGATTTTCCCTCCCTTTCAGAAAGGGACAGCCTCAGTTTTATTCTTCTACAACCACTGGACAATCACGGGGCCCTCGTGTCCCAAGCCCCAGCTCTTTATCTGGCAGCTCTCCGCATCCTTCCTTTTACTCCTCCTACTCAAGTGGTCCTGGTGTACCTCCACGTGATCATCCTTTTCCCCCTCGTCACTCTGATCCATCCCTGTGGGCATCCCCCCAGCACGGCAGTGATCAGATCTCGGACTCAAATGGTGTAAGCTTCCGACAAAACCAGGTGCAGTTCCTCAGGGGGCAGAGTGCACAAGCTCCTCAGTTCAAAGCACCCCAGCCGCGAGGGTCCCAAAGCTCTAGCCGAGGGGAAGAGGTCTCAACTGAGCCTATCCAGTACCAGACGGGTTATCGTGACTTTAAATCAAACAGTTACAGTTTTGGAAGAAGAAACTGTTACGGCAGAGGACAGGATAACTGGCAAGGGGAGCAGAATTTTGGACCTAAAAAAAGGTCAGGGTGGAATCACCCACACCAGAAGGGACAATATTATTCAAATCAGCACTATAAACAATTCTGGAACGCTCGGGCAAATGATTTATCCTCTGGCATCTATAATCTGAGTTTTGGTGACCGTGTAAAAAGGGTAGACACCTCTGATACCTTGTCCTGCAGTAACTCTTCTTCTAAGGTTTCCAGTTCTTCCAGCTCATTCAGAGATTCCCTGTATTTGACCCCTGAGATCCACCAACAGGTCTGTGCTTTTTTGACATCACTCAGGCCAGCTGAGACTATTCAGGCAAAGGTCTTGGGCAAAAAGCTTGGTCTCCCCAAGAAGATTGTTAATAAGGTTTTGTATGACCTTTTGAAGTCAAACCAAGTAGTGAAACAAGGAGAGACCCCCCCTTTGTGGAGACTCTGTGAGGAGAGCCGCGAGTCCATCAGAGAGAAAGACCAAACACAGTCTTCAAAAGATTTGGAAAAAGAGCCAGGTCAGAGTCCATATATAAACCAGAAAGTTGGTGGAGATTTCACTACCACCAGTACTCCCTCTCCATCAAAGATTCCCATTGACGCTGACAGCGATACCAGTGACGAATCAGAGGACTCTGAAGGTGACGATAGCTGTGAAAAGTTGCTTGCAGATCAGGATAAAAAGACTCTTTCACCTACAGTGCAGTCTGTAACATTGTCAACAATGGCTGATTCTAAAGATAGCAAAGAGAAGATCCTACAGTACCTCTATGAAGCAGGTACGGGAAATGCACTTGTGATTGCCAAAAATCTTGGCCTGCGAAGTGCCAAGCAGGTCAATCCCACACTTTATGCCTTGGAGAAACAAGGTGATGTAAACCGCAACACTGAAGTTAATCCACCTACCTGGGAGCTAAGTGCACACAGACAGGAAAAGATGGACCGCCAACGAAAAGCTGCTGCAACTGCAAACCAGGATGTAAACAGTGCTGCAACTCTAAGTTTGGAAGATGACGAGATTGCAAATGTAGCTTTGGTCAACTTTGAGCCAATGGAAGGAGGTGGAAAACCATTGGTTGAGATGTTAGAcaatgacaatgtttttggtaaCACAGAAATTGACATTCCTGGCTTAGAACCGGTATCCAAAGCAAGTGACCTTTCCTCCTCAACCCATCGGAACTTTCAGCCCAATCAGTTTCCCTACTATCAGGAGACTCCCAGTAACGGAGGAGAACAGTCACAGTGGGCATCTGATGATATTCCAGAGTTCCTGAACACAATTCGTTCTGAGGTTGCAGTTTCCTTGGCTGCACCCCCTCCCCCGACCCAAAGCATGGAGTCAAACAGATTGCAGAAACTAAAAGAGGCCCGTAGTAAGAACCCAGTTAGCGGGCTGATGGAGTTTGCACAGCATCTTGGATACACTTGTGAATTCCTACTTTTAGAACAGTCTGGACCCTCACATGACCCCAGGTTTCGGATGCAGGTCATGTTAGATGGTCGCAGGTTTCCAGCAGCTGAGGGTTCAAACAAAAAAGTGGCAAAAAAAGATGCTGCTGCCATTACCCTGAAAATTCTTTGGAAGGAGTTGGATGGAGGAGGTGGAGAGGAAGAGGAAGAACCAAACATTGAGGGAGCTGGGTCAACCACCGATATGGCAGATGATAtgGGTGGCACTGACACTCCACCTCAGGCTCTCTCTCGATCACTACCTGGAGGAAAGAATCCTGTTTCTGTTCTGATGGAGCACAGTCAGCGCAGTGGGCACCCTATCCAGTTTATCAAAACAGGACAGGAAGGGCCCTCTCATGATCCACGGTTTATGTTCCGTGTGAAGGTTGGGGAACGTCTCTTCCAGGAAGCCTCAGCACCTAGTAAGAAGGCAGCAAGACAGCTGGCAGCGGAGGAGGCTGTGAAAGAGCTTATGGGAGACGGACTACTACATCTTAACAAGCCTCCAAGTAGTTTCTGTCCTATGGGTGACAGTGAGTCGCAGCCAATGTTTCCGGCGTGCCCCTCTCTGCCCCCCTTGACTGCAGCTGAGCTTCAGGCAGCCCATGAGGCAGGTGTGGGTGACCTCATCAACCACCTGAACAACAACGCAGTGTCCGGTCTGCTTGAGTACGCCCGTGCTCGAGGCTTCGCTGCTGAGATCCGCCTGGTGGGCCAGTCTGGACCCTCACACGAGCCCAAGTTTACGTACCAGGCTAAATTAGGTGGGCGGTGGTTTCCTGCAGTGTGTGCCAGTAATAAGAAGCAGGGCAAGCAGGAGGCAGCGGACGCTGCTCTTAGAGTGCTCATCGGAGAAGCCGAGAAAGCAGCACGTACTGGAGAGCTCATGCCAGAGttgCCAGTATCAGGGAGTACAATTCATGATCAGATCGCCATGCTAAGCCATCAGCGCTTCAATGCCCTCACTGCACGCATCCAGCACAGCCTTCTGGGTAGAAAAATTCTTGCAACTATTGTGATGCGCAATGGAACGGACAGTCTTGGAAAAGTTGTCAGCCTCGGGACagGAAACCGCTGTGTTAAAGGAGAGGAGCTCAGTCTTCGTGGGGACACTGTAAATGACTGCCATGCAGAAATCATCTCCAGAAGAGGCTTTATCCGGTTTTTGTACAGTGAGCTGATGAAGCACTGGGAAAGCCCTGGCGATGAGACTATTTTTGAGCTGGCAGGTGATGGTAAGCTGAAGATCAAATCTGACATCACCTTTCATCTCTATATTAGCACTGCTCCATGTGGCGACGGTGCTCTCTTTGATAAATCGTGCAGCGAAGCGGCTGAACTCAATGGCTCTGGACACATGCCTCTCTTTGAGAACATCAAACAAGGCAAACTCAGGACCAAAGTGGAGAACGGTGAGGGTACGATCCCAGTGGAGTCCAGTGACATTGTGCCCACCTGGGATGGCATTCAGCATGGCGAGCGCCTGAGGACCATGAGCTGCAGTGATAAGATCCTGCGCTGGAACGTTCTCGGCCTGCAGGGGGCGCTGCTCACACACTTCATCCACCCTATTTATTTGCACTCCATCACTCTTGGATATCTTTACAGCCACGGTCACCTGACTCGAGCTGTGTGCTGCCGATTGTCCAGAGATGGCGATACTTTTAAAAGCAGTTTACCAGCGAACTTTACTCTCAACCACCCTGAGGTGGGCAGGGTGAGTGTGTACGACTCGACACGCCACACAAGTAAGACCAAAGAGTCCAGCGTCAACTGGAGCCAACCAGACCAGTATAGCGTGGAGGTTCTGGATGGCACCAAGGGCAAACTAGACAGTCCCAAGATGGAGGTATCTCGGGTTTCCAAGTCCAATCTGTTCCGTCTCTTCCACGCTTTGTGCCAGCGAGCAGGCCGAGCCGATCTGCTGGCACTGCAGTCTTATGCCCACGCTAAGATGGCCGCCACATCATTCCAGGAAGCCAAGAGGCTGTTCTTTCTGGCACTGAGCCAACATGGATATGGTGCCTGGATTGGGAAGCCCTTGGAGGAGAAAAGTTTCGAAGGTGAAGCCAAAAGCTTTGAGCCGATGGGAGGAAGCGGAGACGTTCAGGCTTCAGGTTGCGTTGTTGACCCCAATAGTTTCTTGAGCTCCGAAAACAACAACTTTCTCTCTGCGGCACAGGGATTTTAGGGCTAGAGGGGGAGATGAAGTCAGCAAATGAGGGGAAGAGGCAGGATTTGAGAAGGTTAGTTGTAGAGATGGAGGAATGGGGTGAATCTGTGGCTTCGGGATTCAAACTTTTAACATTGTGATAAATCAGAAAGAAGTAAAGCAGAGCTTTAAACCCATGGCGAATTGGACTTGATGAAAAATGAAGAAGTAGAGTCAtgccttttttgttttagaaagcTGTAAGCATTTGTTTTAGGAGAGTTCGTCTTTTATTTTCTCCATGTTTGACAGCACCAATGCTGTGTTAGTGACTGGGTGGCCACATAGGCAAGGGATTCGGTTCATCGCTTAAGGTATATTTCACTTAATAAAGAGAGTTTTAACGCTGGTCAGGTCGctgatttacatttatttaaattgaggTTTCCCTGTGTTTCATTCGAGTTGGTTGTAAAGGATTGTGTATTGAGATTTAAAGGGTTTGTTCATTGCAAAATGAAACGTTGTCATTTTGTCACCCTTACCTTTCCTCagtaatttttttgttcattagtttatttagagctgtttctctgtgtgtttttTAACAAAAAGGCATTGATTgctgattttgttttattcaaaaaGAAATATACAGATtgaaaatgatggcagaattttcatttttgcgtgaactaactATTTAATTTCATCAGCATTGTTTTGTCTTTAACCTACTTTGTTTTTTTCATTCCTTTTAAAGTCTTGGTAATACTTTACAGTAAGTATTCATTTTCTAACATGAGTGAAGATTAGTTGACAGGAACTAACAAGAACAGTATACAGTGTATATCTATCATAATCCTAATATCTACAtgaacaaaactcaaatctgctaaagttgtattttttttaaacataaaccaATATGTGTAAGCAATACAACTGTGTTTTTACCAACTTGATCCAacgttaataaatgttttaaaacacattGCTCAAATGTTAGTTCTTTTTAACTAATGGCTTAACTGATGTTAAAAaatgaaaccttactgtaaaCTGTAAGCAAATTTGATTTGCTGATTAAACTTTCTGTAtttacataaa

Function

symbol description
adar Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within defense response to virus. Predicted to be active in cytoplasm and nucleolus. Is expressed in brain. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; dyschromatosis symmetrica hereditaria; and liver cirrhosis. Orthologous to human ADAR (adenosine deaminase RNA specific).

GO:

id name namespace
GO:0006382 adenosine to inosine editing biological_process
GO:0006396 RNA processing biological_process
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004000 adenosine deaminase activity molecular_function
GO:0008251 tRNA-specific adenosine deaminase activity molecular_function
GO:0003723 RNA binding molecular_function
GO:0003725 double-stranded RNA binding molecular_function
GO:0003726 double-stranded RNA adenosine deaminase activity molecular_function

KEGG:

id description
ko04623 Cytosolic DNA-sensing pathway
ko05171 Coronavirus disease - COVID-19
ko05164 Influenza A
ko05162 Measles
ko03041 Spliceosome

ZFIN:

id description
ZDB-GENE-000616-5 Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within defense response to virus. Predicted to be active in cytoplasm and nucleolus. Is expressed in brain. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; dyschromatosis symmetrica hereditaria; and liver cirrhosis. Orthologous to human ADAR (adenosine deaminase RNA specific).

Ensembl:

ensembl_id ENSDARG00000012389

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019725 True 5421 mRNA 0.47 15 23531583 23557714

Neighbor

gene id symbol gene type direction distance location
XLOC_009886 snx27b coding upstream 7209 23495600 ~ 23524374 (+)
XLOC_009885 icn2 coding upstream 40490 23487051 ~ 23491093 (+)
XLOC_009884 icn coding upstream 99031 23431189 ~ 23432552 (+)
XLOC_009883 s100w coding upstream 125428 23403602 ~ 23406155 (+)
XLOC_009882 s100a10b coding upstream 132099 23397785 ~ 23399484 (+)
XLOC_009888 kcnn3 coding downstream 41194 23598908 ~ 23719649 (+)
XLOC_009889 CR533578.1 coding downstream 49517 23607231 ~ 23607352 (+)
XLOC_009890 rab13 coding downstream 238898 23796612 ~ 23809611 (+)
XLOC_009891 si:dkey-7f3.9 coding downstream 253840 23811554 ~ 23835922 (+)
XLOC_009892 nbn coding downstream 280133 23837847 ~ 23977525 (+)
XLOC_009875 NA non-coding upstream 835087 22695226 ~ 22696496 (+)
XLOC_009872 NA non-coding upstream 952257 22575143 ~ 22579326 (+)
XLOC_009870 NA non-coding upstream 1202555 22327970 ~ 22329028 (+)
XLOC_009869 NA non-coding upstream 1204081 22323766 ~ 22327502 (+)
XLOC_009868 NA non-coding upstream 1417647 22022291 ~ 22113936 (+)
XLOC_009902 NA non-coding downstream 461394 24019108 ~ 24028618 (+)
XLOC_009903 NA non-coding downstream 640765 24198479 ~ 24207903 (+)
XLOC_009904 CT867948.1 non-coding downstream 958378 24516092 ~ 24524076 (+)
XLOC_009905 NA non-coding downstream 1008020 24565734 ~ 24573801 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_04860802_04872130 NA coding CI01000027 null 4860802 ~ 4872566 (+)
mexican tetra (Astyanax mexicanus) G127109 NA non-coding NC_035910.1 CM008313.1 34968673 ~ 34969093 (+)