XLOC_030991 (mtmr8)


Basic Information

Item Value
gene id XLOC_030991
gene name mtmr8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 22027588 ~ 22052852 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00060216
ATATTTCCTCCCGTTAGCTGACATGATTGTAGTCCTCATGTTAGGGAGGAACGCGACAGCAAGTTCCTGAAACAAACATGACAACTCCTAAATACCCAAACTCCGAAAGTTTAGCGTGGACAGTTGGATGATAAAACAGTGAAATCATGGAGCACATCATAACGCCGAAGGTGGAGAATGTGAAACTACTGAACAGGTACACTGAAAAGAAGTCAGCTCTGGGCACTCTTTACTTGACCGCGACTCATCTTATCTATGTGGAACAAACCAGCAACACACGCAAAGAAACATGGGTGCTGCATCATCACATCTTGTCAGTGGAGAAACTTCTGTTAACTGCGTCCGGTTGTCCACTGTTGATCCGCTGTAAAACCTTCCAGCATCTGCATCTGCTGTTTCAAAAAGAGAGGGATTGTCAGGATGTGTATCAGTCACTTCTACGGCTTTTTCAACCTGTCAAAGAAGAGGAGCTTTATGCTTTCCTCTATAACCCACATCAAAACGAGGAGGAGCGGAGACGGGGTTGGGAGTTGATCAGTGTGGTGAATGACTTCAACAGGATGGGCCTCTCTAATGATTATTGGGAAATTAGCCATATCAACAAAAACTTTGAGATGTGTAgcacttatccatccatcctagGACTCCCTAAAAGTGCCAGTGTTGCTACGGTAACAGGCAGTGCCAAATTTAGGAGCCGAGGGCGTTTGCCTGTTCTGTCTTACTATCACAAAGATACAAAGGCTGCGATTTGTCGCTGCAGTCAGCCTTTGTCAGGTTTGAACTCCCGCTGTGTGGAAGACGAGCAGATGCTTCAGGCCATCAGCCAAGCCAATCCAAACTCTCCCTTTATATATGTAGTGGACACACGGCCCAAGTTGAATGCAATGGCGAACCGTGCAGCTGGTAAAGGCTATGAGAACGAGGACAATTACTCCAATATCAGGTTCCAGTTTCAGGGAATTGAAAACATCCATGTCATGAGAAGCAGCCTGCAAAAACTGCTGGAGGTTTGCTCTATGAAGTCTCCCTCTATGAGTGACTATCTGACAGGACTGGAGAACTCTGGCTGGTTGAGACACATCAAATCTGTGATGGATGCAGGGGTCTTCCTCGCCAAGGCTGTGTGTGAAGAGAGAGCGAGTGTATTAGTACACTGTTCCGATGGTTGGGACAGAACTGCTCAGGTTTGCTCTCTGGCTTGCTTACTGCTGGATCCATACTACAGAACTATTAAAGGCCTCATGgtTTTAATAGAAAAAGAGTGGATTTCTTTTGGTCATAAATTCAGTCACAGGTGTGGCCATCTGGACAGCGACCCAAAGGAAGCGTCTCCGGTGTTCACCCAGTTCCTGGAGTGCGTCTGGCAGCTGTCACAACAATTCCCCTGTGTGTTTGAGTTCAACGAACATTACCTGATAGAAATACATGACCAAGTCTACGCCTGCCAGTACGGAAACTTCATCGGCAACTGTCAGAAGGAGAGGCTAGACATGAGgTTGCATGAAAAAACCTTTTCCCTGTGGCCGCATCTTCTGGAAAACCAGCATCAGTATCGAAACCCTTTGTACCGGCGCTCATTAGAAAGCACAGTTCTCAGACCAAGCACTTTACCACTACACTTCAAGTTCTGGTGTGGGATGTATAACCACTATGACAGAGGAATGCACCCAAAACAGTCTGTTCTAGACACGCTGCTGACTCTCACACAGAGGCAGGTAGAAGGAGAGAGAACCATGACTGAATTACAGAGACAGCTGGCTGTTGCAGATGGAGTTCTTCCTGATCCAGCCGGACCAATCAACACACATGCAGACCAGAATAACCAAAGTGAGAAGATGCCTGCTCCTCCAGTCGTCCAATCAAATGGAAGCTGTGCTCCTTTGATCAATGGCAACGTGAAGGAGGTGGGGCCAGGAGCTGAAAACTCCAATCAGGAAGACAGGGAGGAGCCAGCTGCCAATGAACACGATCTGTCCTCTAAGGACAAACCTGTTTTTGTGGAAACAGAACATTCCAAAGAGGAGGTACAGGAATCCTCTTGAGTCGCCATAGTGTTAGCACATCAGCCGTTAGGACTGAAATGCCAAAGAACAAATGAAAGCATGCATAAAGTTGTGTTCCCACAACAGAAGCCAtcgcaatagaaaaaaaaacaatcatttaaaCGGCAGTGTTCTTCTGCACACCATGTTGTGATGGTGTACTGATGTTTCTATCACTGTGTGGATTGTTTTGTCCAGTTATATCTGTTCTGAACATTCCCAAAATGTTAAAGACATGTATGTGGCATGATGATTAAAAGCTAGGTGCTTTGATCATAGGCAATGAGaatcatctgttttgtttaaatgcccaATTGGATCATATTTCATCTTGTTTCACtggaaacaaacacaaaatgttacaggaaaacaaaatgtattgtacatttgAAAACCTGAAACGGATTTATTCAGATGCATAGGTGTCTGATCAGAAAATCAGCTTGATAAAGGGAACACTGTTagaaaatggatcaaattattattatttttgcatattattttgCTTGAGAGTGCCAGTGAGCTGTGCAATTTGAATTAAAGGGGAAAAcagcttttttaattaaatattataaatatttgtcattttagCCAAGCCTTTTACATATTTCGCTTTCCAAAGCAATATTTTGATGATGTCTACTGGACTTGATGAGTGTATTGAGTGTATTGCGAAAGCATGTGGgaaaaaaatgtaagatttttaggTCTAGACTAAAGTTTAAGTTCTAACGTGAGATGAAAAATCAATGTTTAAAGCGCTTCATTCATGAGAAGTGTTtgcttacattatttttttattgaattaaaaaggaaaaaatgttTTCTGTTGAATAAACGCTTAGCAATACACAATAGGAAATTCTGAAATAAGCAATGAAAGTAAAGCCATTGGAAATAACAGACTGTGGTGACATACTgctgttgtttttaaaactgtagagttttgttttgtgtaataATTTCTACACGTCATCATTTTATACACTTTGTTTTGATCATTGTACTGTTTTGTATCTTTTTGTACACCATTCAATTCAAATggatgtttgttttaaataaatacactttattaAATGTG
>TCONS_00060217
ttgaagcggcgccacggtgttgttgtgaaagcatcttccagtgtttctgcatccccggctttcgcactgcttcaaccagctccaaaagtgGCTGCGATTTGTCGCTGCAGTCAGCCTTTGTCAGGTTTGAACTCCCGCTGTGTGGAAGACGAGCAGATGCTTCAGGCCATCAGCCAAGCCAATCCAAACTCTCCCTTTATATATGTAGTGGACACACGGCCCAAGGTGCGACCTTTAACCTTAACCTTTCTATATACATAAGGGTGACAAGTCCAGGATGGGACACGTAAGTGTTTATCTTTAAACTTTCAACCCTGAATGCTCTGATGCACATGTACTGTAGGAATGTAATCCTTCACCTACTGACATCTGACCCCAGCTTTATTTATTGAACTAATGATTAAAAATGAGATGAGTGCCTAAAGGATATTGGAGAAATCTGGCATTGTGATATTTATTGTTTCTGCAATATACATTGCAATAAGagtacaatttcactagatggcTTAAACAACTCTTGAATAAAtcttgaa
>TCONS_00060218
gtTCTGTAGATGAACAAAgatctcaggggattggaatgacTTAagGTGCTGCATCATCACATCTTGTCAGTGGAGAAACTTCTGTTAACTGCGTCCGGTTGTCCACTGTTGATCCGCTGTAAAACCTTCCAGCATCTGCATCTGCTGTTTCAAAAAGAGAGGGATTGTCAGGATGTGTATCAGTCACTTCTACGGCTTTTTCAACCTGTCAAAGAAGAGGAGCTTTATGCTTTCCTCTATAACCCACATCAAAACGAGGAGGAGCGGAGACGGGGTTGGGAGTTGATCAGTGTGGTGAATGACTTCAACAGGATGGGCCTCTCTAATGATTATTGGGAAATTAGCCATATCAACAAAAACTTTGAGATGTGTAgcacttatccatccatcctagGACTCCCTAAAAGTGCCAGTGTTGCTACGGTAACAGGCAGTGCCAAATTTAGGAGCCGAGGGCGTTTGCCTGTTCTGTCTTACTATCACAAAGATACAAAGGCTGCGATTTGTCGCTGCAGTCAGCCTTTGTCAGGTTTGAACTCCCGCTGTGTGGAAGACGAGCAGATGCTTCAGGCCATCAGCCAAGCCAATCCAAACTCTCCCTTTATATATGTAGTGGACACACGGCCCAAGGTGCGACCTTTAACCTTAACCTTTCTATATACATAAGGGTGACAAGTCCAGGATGGGACACGTAAGTGTTTATCTTTAAACTTTCAACCCTGAATGCTCTGATGCACATGTACTGTAGGAATGTAATCCTTCACCTACTGACATCTGACCCCAGCTTTATTTATTGAACTAATGATTAAAAATGAGATGAGTGCCTAAAGGATATTGGAGAAATCTGGCATTGTGATATTTATTGTTTCTGCAATATACATTGCAATAAGagtacaatttcactagatggcTTAAACAACTCTTGAATAAAtcttgaa

Function

symbol description
mtmr8 Enables MAP kinase kinase activity. Acts upstream of or within blood vessel development and phosphatidylinositol 3-kinase signaling. Predicted to be located in nucleus. Predicted to be active in cytoplasm; membrane; and nuclear envelope. Is expressed in several structures, including anterior axial hypoblast; immature eye; optic primordium; vasculature; and ventral mesoderm. Orthologous to human MTMR8 (myotubularin related protein 8).

GO:

id name namespace
GO:0046856 phosphatidylinositol dephosphorylation biological_process
GO:0001568 blood vessel development biological_process
GO:0010506 regulation of autophagy biological_process
GO:0010507 negative regulation of autophagy biological_process
GO:0014065 phosphatidylinositol 3-kinase signaling biological_process
GO:0016311 dephosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0005635 nuclear envelope cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity molecular_function
GO:0004708 MAP kinase kinase activity molecular_function
GO:0004725 protein tyrosine phosphatase activity molecular_function
GO:0004438 phosphatidylinositol-3-phosphatase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1016 Enables MAP kinase kinase activity. Acts upstream of or within blood vessel development and phosphatidylinositol 3-kinase signaling. Predicted to be located in nucleus. Predicted to be active in cytoplasm; membrane; and nuclear envelope. Is expressed in several structures, including anterior axial hypoblast; immature eye; optic primordium; vasculature; and ventral mesoderm. Orthologous to human MTMR8 (myotubularin related protein 8).

Ensembl:

ensembl_id ENSDARG00000008592

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00060216 False 3126 mRNA 0.42 14 22027588 22052852
TCONS_00060217 False 533 lncRNA 0.43 2 22040277 22041856
TCONS_00060218 True 938 lncRNA 0.43 5 22040277 22045634

Neighbor

gene id symbol gene type direction distance location
XLOC_030990 asb12a coding downstream 231 22021142 ~ 22027357 (-)
XLOC_030989 amer1 coding downstream 8527 22011575 ~ 22019061 (-)
XLOC_030988 arhgef9a coding downstream 26535 21939733 ~ 22001053 (-)
XLOC_030987 NA coding downstream 93310 21926822 ~ 21934278 (-)
XLOC_030986 smarca1 coding downstream 139220 21852714 ~ 21888368 (-)
XLOC_030992 zc4h2 coding upstream 20858 22073710 ~ 22082918 (-)
XLOC_030993 CR812469.1 coding upstream 34804 22087656 ~ 22096908 (-)
XLOC_030994 las1l coding upstream 62398 22115250 ~ 22130937 (-)
XLOC_030995 NA coding upstream 177838 22230690 ~ 22235158 (-)
XLOC_030996 GPR83 coding upstream 310163 22363015 ~ 22369916 (-)
XLOC_030984 NA non-coding downstream 175361 21609358 ~ 21852227 (-)
XLOC_030985 CR848717.1 non-coding downstream 290243 21736359 ~ 21737345 (-)
XLOC_030982 BX470224.4 non-coding downstream 734343 21293130 ~ 21293245 (-)
XLOC_030981 NA non-coding downstream 785504 21239333 ~ 21242084 (-)
XLOC_030997 BX546499.2 non-coding upstream 382934 22435786 ~ 22438595 (-)
XLOC_030998 NA non-coding upstream 400978 22453830 ~ 22455994 (-)
XLOC_030999 NA non-coding upstream 402714 22455566 ~ 22457289 (-)

Expression


Co-expression Network