XLOC_009072 (numbl)


Basic Information

Item Value
gene id XLOC_009072
gene name numbl
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 14436159 ~ 14552101 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00017875
AAAAAATCCGTCCATTTCTTACGGCCGTTTTACTAAATTTACGACCGTCCGAAACGCCTTAGTCCACGTGCCTCCAACCGAGCGTCAGTTTCGCGAGGGATTCTCATGTAGATTCATCTGAAGTTATTTCCCCCCTCATATTTCTGTGGATTACACAAAAGGCGGCACGGACACTCATTGTAGTATTCTTCTATTCGCACCAGAGAGTTTGAGAGCGTGGAGATGAATAAGCTGCGTCAGAGCCTGCGCAGGAAGAAGCCCACCTACGTGCCAGAGGCCAGTCGACCACACCAGTGGCAGGCGGATGAAGAGGCTGTGCGAAAGGGCAAATGCAACTTTCCTGTCCGGtatCTCGGGCTGGTGGAGGTGGATGAATCCAGAGGCATGCATGTGTGTGAAGAGGCAGTGAAAAAGCTAAAAGTGAGTGGGAAAAAGACAGTGAAGGCTGTGCTCTGGGTGTCTGCTGATGGCCTGAGAGTAGTGGACGACAAAACCAAGgACCTGATTGTGGATCAGACGATTGAAAAGGTGTCATTCTGTGCCCCGGACCGTAACTACGACAAGGCTTTCTCTTACATCTGCCGTGACGGAACGACCCGCCGCTGGATGTGCCACTGCTTCATGGCCCTGAAGGACTCGGGCGAGCGTCTCAGTCATGCAGTGGGATGTGCGTTTGCCGCCTGCCTGGAGCGGAAGCAGCGCAGAGAAAAGGAGTGTGGCGTCACAGCCTCTTTCGATGCCAGCAGAACATCATTTGTGAGGGAAGGTTCATTCCGCGTGTCCTCCGCCGCACAACAGAGTGACCGTGAGGACATCATGAAGCAGATTCAAGACAAGAAGAAAGAAATGTGTGGGATTTCTGCATTGCCGCCTGGAAATGCATCTCCTCCAGAAGGGGCGGGGTCACCGGGTGAGAGGGCGGAGCCAGGTGGCCCTCACGCCATTCCACGCAGACACGCCCCCATCGAGCAGCTGGTGCGACAGGGATCCTTCAGAGGCTTTCCTCAACTCAGCCAGAAGAACTCGCCGTTCAAACGACAGCTTTCTCTGCGTCTCAATGATCTCCCGTCAACCCTGCAGCGCAAGACCGACTTCCAGACCAAGAACCCAGTTCCAGAGATGGATCTGACAGTGGCTGGAGAGGCGGACAGCATTAACGCTCTGTGCAGCCAAATCAATAGCTCTTTCACCAAACCATCTGAAGACCTGTGTGCCAAAACCACCAACAACTGCTTACCCATCAGCTGCGCTCCACCTGCCATCCCTCCTCCACCTGCCCCTCCTCAAGCTACAAATTTATGGGTCCAAATAGAGCCCCCGGTCCAGTCTTCTCCACCCATTCCTCAGGGTGGCCACAAACGAACCCCGTCCGAAGCAGAACGATGGCTGGAGGAAGTTGCTAAAGCGGTGAAATCCCAACAGCAGACTCCACCTACTTTACCACCACCACCCACTCAGCAGCCTCCACCGGTGCCCACCATGCCCATTGCACCCGGTTCCCTCCCAACATCCATGCAGCCATTTCCGATGGCTTTTGACGTCACTCCTGCTCCCGTTAGTATGTTCACCCAACAGCCGCTCCAACCGGCGTTTGTACCTATGCAGCCGTACATGCCCACTCTAGCCAACAGCATGACCTATCCCAATGCAAGTGTACCCGTGGTGGGCATCACACCCTCACAGATGGTGGCGAATGTATTTTGCAGTGCAGCCGGTACAGGAGGTGGAGTGGCAATTGGGGTCGGGATGGGGCCTAAGACGGGTACGCTTGGCGGGAGCCAACATTCAGCATTTCCCACCCTTCCTGGAGGTCTTCCAACCACCACGTTCGCTTCTCCTCCAACAATCAATGGCCACCCACAAAACTCCTTTCCATCAACGACCACCAGTGTTACGCAAAACGGTACTGCCGTTAAAGGAGGTTCTGGTTGGCCCATGGAGAATCCGAATCCCACAATCAACTCCAAGGAAGCCGAGCATTTCGATGCAAAGTGGGCCGCCCTGGAGTCCAAATCACAACCCAAGGCGCAAAACCCATTTTCCAACGACTTGCAGAAGACTTTTGAGATTGAACTATAATTGTAAGGAGACTCTGAAAAGAAGGGACTATTTCATACCCCCCTTTTTTGTCCCTTCAAGGATTTTCTTATATGCTCCTGGTCTGTTTGAGGGCATTAGTTGATGTAAGAGATCACACAAGAGTGTCATTTTTAGATATGGAGAATGGGAACAGACGTCATAACATGTTCGGCACTTACAGGACAGCTTAAAAGAGAAACCTGCACATGACTTTCACCAGTAATGACACTtgcttttaaagaaattaatgattttttaaaagtaatatcgAAATTAAGAGACGTTCGGaatctatttattgtttttacttgATTTATAGTGCTTATTTCTTAATTGGATTTTGAATTATTCTTGGTTTTTCCGTATTTATTTGTCTTGAACAGGGTGACAAGATTACAGGTGGAATGATTGGCTACTTGAAAATGGACTCACCAAAATGCTTGATTTAAAAATC
>TCONS_00017876
TTAAATAATTGCCTTCTTCCGAGCGGCCTTGCTTTCTGAATTTGAAATTACCAATGCAAATTAAGGCTAGAATGAATGACCCAATTATGCTGCATAAACAGGGCTCTTGGGCATCAAACAATTGTTTTGAAAACAGAGGCCAATACATTCTCTGCGATTTCAGTTTAATCCAATACGCCATGCTGCTTTTAATTCCATAATAAtactcaaaaaatatgtttggATTTAATTAGtgttgctattttttattttggttttgatcCAAATCAGAGTGATTACTCCCCGCTTGTCCAGCATGACtgtaaataactgtataaaacattCAGCAGGATTTGTCCTGACGATAAATTTAACTAATAGTCTCTAATTTAGAAAAAGGGCTGTTTGTTGAtgtgtcttgtttcttgtcctcAGCACCAGAGAGTTTGAGAGCGTGGAGATGAATAAGCTGCGTCAGAGCCTGCGCAGGAAGAAGCCCACCTACGTGCCAGAGGCCAGTCGACCACACCAGTGGCAGGCGGATGAAGAGGCTGTGCGAAAGGGCAAATGCAACTTTCCTGTCCGGtatCTCGGGCTGGTGGAGGTGGATGAATCCAGAGGCATGCATGTGTGTGAAGAGGCAGTGAAAAAGCTAAAAGTGAGTGGGAAAAAGACAGTGAAGGCTGTGCTCTGGGTGTCTGCTGATGGCCTGAGAGTAGTGGACGACAAAACCAAGgACCTGATTGTGGATCAGACGATTGAAAAGGTGTCATTCTGTGCCCCGGACCGTAACTACGACAAGGCTTTCTCTTACATCTGCCGTGACGGAACGACCCGCCGCTGGATGTGCCACTGCTTCATGGCCCTGAAGGACTCGGGCGAGCGTCTCAGTCATGCAGTGGGATGTGCGTTTGCCGCCTGCCTGGAGCGGAAGCAGCGCAGAGAAAAGGAGTGTGGCGTCACAGCCTCTTTCGATGCCAGCAGAACATCATTTGTGAGGGAAGGTTCATTCCGCGTGTCCTCCGCCGCACAACAGAGTGACCGTGAGGACATCATGAAGCAGATTCAAGACAAGAAGAAAGAAATGTGTGGGATTTCTGCATTGCCGCCTGGAAATGCATCTCCTCCAGAAGGGGCGGGGTCACCGGGTGAGAGGGCGGAGCCAGGTGGCCCTCACGCCATTCCACGCAGACACGCCCCCATCGAGCAGCTGGTGCGACAGGGATCCTTCAGAGGCTTTCCTCAACTCAGCCAGAAGAACTCGCCGTTCAAACGACAGCTTTCTCTGCGTCTCAATGATCTCCCGTCAACCCTGCAGCGCAAGACCGACTTCCAGACCAAGAACCCAGTTCCAGAGATGGATCTGACAGTGGCTGGAGAGGCGGACAGCATTAACGCTCTGTGCAGCCAAATCAATAGCTCTTTCACCAAACCATCTGAAGACCTGTGTGCCAAAACCACCAACAACTGCTTACCCATCAGCTGCGCTCCACCTGCCATCCCTCCTCCACCTGCCCCTCCTCAAGCTACAAATTTATGGGTCCAAATAGAGCCCCCGGTCCAGTCTTCTCCACCCATTCCTCAGGGTGGCCACAAACGAACCCCGTCCGAAGCAGAACGATGGCTGGAGGAAGTTGCTAAAGCGGTGAAATCCCAACAGCAGACTCCACCTACTTTACCACCACCACCCACTCAGCAGCCTCCACCGGTGCCCACCATGCCCATTGCACCCGGTTCCCTCCCAACATCCATGCAGCCATTTCCGATGGCTTTTGACGTCACTCCTGCTCCCGTTAGTATGTTCACCCAACAGCCGCTCCAACCGGCGTTTGTACCTATGCAGCCGTACATGCCCACTCTAGCCAACAGCATGACCTATCCCAATGCAAGTGTACCCGTGGTGGGCATCACACCCTCACAGATGGTGGCGAATGTATTTTGCAGTGCAGCCGGTACAGGAGGTGGAGTGGCAATTGGGGTCGGGATGGGGCCTAAGACGGGTACGCTTGGCGGGAGCCAACATTCAGCATTTCCCACCCTTCCTGGAGGTCTTCCAACCACCACGTTCGCTTCTCCTCCAACAATCAATGGCCACCCACAAAACTCCTTTCCATCAACGACCACCAGTGTTACGCAAAACGGTACTGCCGTTAAAGGAGGTTCTGGTTGGCCCATGGAGAATCCGAATCCCACAATCAACTCCAAGGAAGCCGAGCATTTCGATGCAAAGTGGGCCGCCCTGGAGTCCAAATCACAACCCAAGGCGCAAAACCCATTTTCCAACGACTTGCAGAAGACTTTTGAGATTGAACTATAATTGTAAGGAGACTCTGAAAAGAAGGGACTATTTCATACCCCCCTTTTTTGTCCCTTCAAGGATTTTCTTATATGCTCCTGGTCTGTTTGAGGGCATTAGTTGATGTAAGAGATCACACAAGAGTGTCATTTTTAGATATGGAGAATGGGAACAGACGTCATAACATGTTCGGCACTTACAGGACAGCTTAAAAGAGAAACCTGCACATGACTTTCACCAGTAATGACACTtgcttttaaagaaattaatgattttttaaaagtaatatcgAAATTAAGAGACGTTCGGaatctatttattgtttttacttgATTTATAGTGCTTATTTCTTAATTGGATTTTGAATTATTCTTGGTTTTTCCGTATTTATTTGTCTTGAACAGGGTGACAAGATTACAGGTGGAATGATTGGCTACTTGAAAATGGACTCACCAAAATGCTTGATTT
>TCONS_00017877
CCTGGACAGACGGCAGGTGTAAAGGGTCTAAAAGCTCAGCAACAGGCACGTGCCGGAGCAGAATAAACCCTCTGGAGAGACCCAGACGCCAGAGAAATAAAGCACACTCATATGTAGCAGCATGTGGCCTGACACCAGAGAGTTTGAGAGCGTGGAGATGAATAAGCTGCGTCAGAGCCTGCGCAGGAAGAAGCCCACCTACGTGCCAGAGGCCAGTCGACCACACCAGTGGCAGGCGGATGAAGAGGCTGTGCGAAAGGGCAAATGCAACTTTCCTGTCCGGtatCTCGGGCTGGTGGAGGTGGATGAATCCAGAGGCATGCATGTGTGTGAAGAGGCAGTGAAAAAGCTAAAAGTGAGTGGGAAAAAGACAGTGAAGGCTGTGCTCTGGGTGTCTGCTGATGGCCTGAGAGTAGTGGACGACAAAACCAAGgACCTGATTGTGGATCAGACGATTGAAAAGGTGTCATTCTGTGCCCCGGACCGTAACTACGACAAGGCTTTCTCTTACATCTGCCGTGACGGAACGACCCGCCGCTGGATGTGCCACTGCTTCATGGCCCTGAAGGACTCGGGCGAGCGTCTCAGTCATGCAGTGGGATGTGCGTTTGCCGCCTGCCTGGAGCGGAAGCAGCGCAGAGAAAAGGAGTGTGGCGTCACAGCCTCTTTCGATGCCAGCAGAACATCATTTGTGAGGGAAGGTTCATTCCGCGTGTCCTCCGCCGCACAACAGAGTGACCGTGAGGACATCATGAAGCAGATTCAAGACAAGAAGAAAGAAATGTGTGGGATTTCTGCATTGCCGCCTGGAAATGCATCTCCTCCAGAAGGGGCGGGGTCACCGGGTGAGAGGGCGGAGCCAGGTGGCCCTCACGCCATTCCACGCAGACACGCCCCCATCGAGCAGCTGGTGCGACAGGGATCCTTCAGAGGCTTTCCTCAACTCAGCCAGAAGAACTCGCCGTTCAAACGACAGCTTTCTCTGCGTCTCAATGATCTCCCGTCAACCCTGCAGCGCAAGACCGACTTCCAGACCAAGAACCCAGTTCCAGAGATGGATCTGACAGTGGCTGGAGAGGCGGACAGCATTAACGCTCTGTGCAGCCAAATCAATAGCTCTTTCACCAAACCATCTGAAGACCTGTGTGCCAAAACCACCAACAACTGCTTACCCATCAGCTGCGCTCCACCTGCCATCCCTCCTCCACCTGCCCCTCCTCAAGCTACAAATTTATGGGTCCAAATAGAGCCCCCGGTCCAGTCTTCTCCACCCATTCCTCAGGGTGGCCACAAACGAACCCCGTCCGAAGCAGAACGATGGCTGGAGGAAGTTGCTAAAGCGGTGAAATCCCAACAGCAGACTCCACCTACTTTACCACCACCACCCACTCAGCAGCCTCCACCGGTGCCCACCATGCCCATTGCACCCGGTTCCCTCCCAACATCCATGCAGCCATTTCCGATGGCTTTTGACGTCACTCCTGCTCCCGTTAGTATGTTCACCCAACAGCCGCTCCAACCGGCGTTTGTACCTATGCAGCCGTACATGCCCACTCTAGCCAACAGCATGACCTATCCCAATGCAAGTGTACCCGTGGTGGGCATCACACCCTCACAGATGGTGGCGAATGTATTTTGCAGTGCAGCCGGTACAGGAGGTGGAGTGGCAATTGGGGTCGGGATGGGGCCTAAGACGGGTACGCTTGGCGGGAGCCAACATTCAGCATTTCCCACCCTTCCTGGAGGTCTTCCAACCACCACGTTCGCTTCTCCTCCAACAATCAATGGCCACCCACAAAACTCCTTTCCATCAACGACCACCAGTGTTACGCAAAACGGTACTGCCGTTAAAGGAGGTTCTGGTTGGCCCATGGAGAATCCGAATCCCACAATCAACTCCAAGGAAGCCGAGCATTTCGATGCAAAGTGGGCCGCCCTGGAGTCCAAATCACAACCCAAGGCGCAAAACCCATTTTCCAACGACTTGCAGAAGACTTTTGAGATTGAACTATAA
>TCONS_00017878
ATGAGTTTCAGCAGTGACATGGATGAGACTGAAGATGGGAGCACCAGAGAGTTTGAGAGCGTGGAGATGAATAAGCTGCGTCAGAGCCTGCGCAGGAAGAAGCCCACCTACGTGCCAGAGGCCAGTCGACCACACCAGTGGCAGGCGGATGAAGAGGCTGTGCGAAAGGGCAAATGCAACTTTCCTGTCCGGtatCTCGGGCTGGTGGAGGTGGATGAATCCAGAGGCATGCATGTGTGTGAAGAGGCAGTGAAAAAGCTAAAAGTGAGTGGGAAAAAGACAGTGAAGGCTGTGCTCTGGGTGTCTGCTGATGGCCTGAGAGTAGTGGACGACAAAACCAAGgACCTGATTGTGGATCAGACGATTGAAAAGGTGTCATTCTGTGCCCCGGACCGTAACTACGACAAGGCTTTCTCTTACATCTGCCGTGACGGAACGACCCGCCGCTGGATGTGCCACTGCTTCATGGCCCTGAAGGACTCGGGCGAGCGTCTCAGTCATGCAGTGGGATGTGCGTTTGCCGCCTGCCTGGAGCGGAAGCAGCGCAGAGAAAAGGAGTGTGGCGTCACAGCCTCTTTCGATGCCAGCAGAACATCATTTGTGAGGGAAGGTTCATTCCGCGTGTCCTCCGCCGCACAACAGAGTGACCGTGAGGACATCATGAAGCAGATTCAAGACAAGAAGAAAGAAATGTGTGGGATTTCTGCATTGCCGCCTGGAAATGCATCTCCTCCAGAAGGGGCGGGGTCACCGGGTGAGAGGGCGGAGCCAGGTGGCCCTCACGCCATTCCACGCAGACACGCCCCCATCGAGCAGCTGGTGCGACAGGGATCCTTCAGAGGCTTTCCTCAACTCAGCCAGAAGAACTCGCCGTTCAAACGACAGCTTTCTCTGCGTCTCAATGATCTCCCGTCAACCCTGCAGCGCAAGACCGACTTCCAGACCAAGAACCCAGTTCCAGAGATGGATCTGACAGTGGCTGGAGAGGCGGACAGCATTAACGCTCTGTGCAGCCAAATCAATAGCTCTTTCACCAAACCATCTGAAGACCTGTGTGCCAAAACCACCAACAACTGCTTACCCATCAGCTGCGCTCCACCTGCCATCCCTCCTCCACCTGCCCCTCCTCAAGCTACAAATTTATGGGTCCAAATAGAGCCCCCGGTCCAGTCTTCTCCACCCATTCCTCAGGGTGGCCACAAACGAACCCCGTCCGAAGCAGAACGATGGCTGGAGGAAGTTGCTAAAGCGGTGAAATCCCAACAGCAGACTCCACCTACTTTACCACCACCACCCACTCAGCAGCCTCCACCGGTGCCCACCATGCCCATTGCACCCGGTTCCCTCCCAACATCCATGCAGCCATTTCCGATGGCTTTTGACGTCACTCCTGCTCCCGTTAGTATGTTCACCCAACAGCCGCTCCAACCGGCGTTTGTACCTATGCAGCCGTACATGCCCACTCTAGCCAACAGCATGACCTATCCCAATGCAAGTGTACCCGTGGTGGGCATCACACCCTCACAGATGGTGGCGAATGTATTTTGCAGTGCAGCCGGTACAGGAGGTGGAGTGGCAATTGGGGTCGGGATGGGGCCTAAGACGGGTACGCTTGGCGGGAGCCAACATTCAGCATTTCCCACCCTTCCTGGAGGTCTTCCAACCACCACGTTCGCTTCTCCTCCAACAATCAATGGCCACCCACAAAACTCCTTTCCATCAACGACCACCAGTGTTACGCAAAACGGTACTGCCGTTAAAGGAGGTTCTGGTTGGCCCATGGAGAATCCGAATCCCACAATCAACTCCAAGGAAGCCGAGCATTTCGATGCAAAGTGGGCCGCCCTGGAGTCCAAATCACAACCCAAGGCGCAAAACCCATTTTCCAACGACTTGCAGAAGACTTTTGAGATTGAACTATAA

Function

symbol description
numbl Acts upstream of or within determination of left/right symmetry; negative regulation of Notch signaling pathway; and primitive erythrocyte differentiation. Located in cytoplasm. Is expressed in immature eye; integument; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human NUMBL (NUMB like endocytic adaptor protein).

GO:

id name namespace
GO:0045746 negative regulation of Notch signaling pathway biological_process
GO:0007275 multicellular organism development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0050769 positive regulation of neurogenesis biological_process
GO:0007399 nervous system development biological_process
GO:0060319 primitive erythrocyte differentiation biological_process
GO:0005737 cytoplasm cellular_component

KEGG:

id description
ko04330 Notch signaling pathway
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-051113-340 Acts upstream of or within determination of left/right symmetry; negative regulation of Notch signaling pathway; and primitive erythrocyte differentiation. Located in cytoplasm. Is expressed in immature eye; integument; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human NUMBL (NUMB like endocytic adaptor protein).

Ensembl:

ensembl_id ENSDARG00000101949

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00017875 False 2533 mRNA 0.51 9 14436159 14552101
TCONS_00017876 False 2743 mRNA 0.49 8 14436166 14467394
TCONS_00017877 False 2014 mRNA 0.55 9 14436613 14469704
TCONS_00017878 True 1923 mRNA 0.55 9 14436613 14486534

Neighbor

gene id symbol gene type direction distance location
XLOC_009070 dpf1 coding downstream 60588 14257232 ~ 14375571 (-)
XLOC_009071 BX957341.1 coding downstream 120689 14315354 ~ 14315470 (-)
XLOC_009069 NA coding downstream 188112 14246090 ~ 14248047 (-)
XLOC_009068 NA coding downstream 204089 14229248 ~ 14232070 (-)
XLOC_009067 NA coding downstream 223382 14203675 ~ 14212777 (-)
XLOC_009073 coq8b coding upstream 2197 14554298 ~ 14589677 (-)
XLOC_009074 slc5a2 coding upstream 50419 14602520 ~ 14625373 (-)
XLOC_009075 si:dkey-260j18.2 coding upstream 78589 14630690 ~ 14642186 (-)
XLOC_009076 CR388387.1 coding upstream 83568 14635669 ~ 14635785 (-)
XLOC_009077 p4ha3 coding upstream 122827 14674928 ~ 14755318 (-)
XLOC_009063 NA non-coding downstream 371809 14062613 ~ 14064350 (-)
XLOC_009061 BX897750.1 non-coding downstream 611555 13824472 ~ 13824604 (-)
XLOC_009080 CR936977.1 non-coding upstream 331190 14883291 ~ 14884061 (-)
XLOC_009081 NA non-coding upstream 476111 15028212 ~ 15030391 (-)
XLOC_009083 NA non-coding upstream 751626 15303727 ~ 15307751 (-)
XLOC_009085 NA non-coding upstream 821958 15374059 ~ 15375518 (-)

Expression


Co-expression Network