XLOC_000976 (mxa)


Basic Information

Item Value
gene id XLOC_000976
gene name mxa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 7562316 ~ 7570181 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001544
CTGAAACTTTGTTGTGATAAGGATTTGTCTTTGGACATTATTAAGGATGGAGAAGTTGAGTTACACGTTCAGTCAGCAATATGAGGAGAAAATTCGCCCTTGTATCGACACTATCGATAATTTACGGTCTCTGGGAGTCGAAAAGGACCTCGCGTTGCCTGCCATCGCCGTCATAGGAGACCAAAGCTCGGGAAAGAGTTCGGTTCTGGAGGCGCTGTCAGGAGTTCCGTTACCCAGGGGCAGTGGGATTGTTACACGGTGCCCTCTCGAGCTCAAGATGATAAGAACTAAAGACCAAGATAAGTGGCATGGGAGAATCAGTTACAAAACCTATGAGGAGGACTTCGATGACCCAGCGGAAGTGGAGAAAAAGATCCGCCAagCCCAAGATGAGATGGCTGGAGCAGGTGTTGGTATCAGTGAAGAACTCATCAGTCTGCAGATCACCTCTGCCAATGTTCCTGACCTCACTCTCATTGACCTCCCTGGCATTGCACGAGTGGCCGTCAAGGGTCAACCTGAGAACATTGGAGATCAGATTAAAAGACTAATCAGGAAGTTTGTTACAAGGCAAGAGACAATCAACCTGGTCGTGGTGCCATGCAATGTTGACATCGCCACCACAGAAGCATTGCAGATGGCTCAGGCAGAGGATCCTGATGGCGAAAGGACTTTAGGCATCTTAACAAAGCCAGACCTGGTGGACAAGGGCACTGAAGGGACAGTTGTAGACATTGTCCACAATGAGGTCATTCACCTCACTAAAGGCTACATGATTGTAAGGTGCAGAGGGCAAAAAGAGATTATGGATCAGGTCACTCTAAATGAGGCTACAGAAACAGAGAGTGCCTTCTTCAAAGACCATCCTCATTTCAGCAAACTCTATGAAGAGGGTTTTGCTACTATTCCCAAGTTGGCAGAGAAACTAACAATTGAATTGGTTCATCACATTCAGAAATCTCTACCTCGCCTAGAAGAGCAAATAGAGACAAAGCTTGCTGAAACACAGAAGGAACTAGAGGCATATGGCAATGGGCCTCCATCAGAACCAGCAGCAAGACTCAGCTTTTTCATTGACAAAGTTACAGCTTTCAATCAAGATATGCTGAACCTGACGACTGGGGAGGATGTTAAATGTACTACAGATCTACTGCTTTTCCCAGAACTTCGGCAAGAATTTGCAAAATGGAGTCACATCTTGGATCGTTCAGGGGATTCATTCAACAAAAAGATTGAGAAAGAAGTTGATAACTACGAAGTCAAGTACCGGGGAAGAGAGCTACCAGGATTCATCAACTACAAGACCTTTGAGGGGCTTGTCAGGGACCAGATCAAGCTGTTGGAGGAACCTGCGTTAAAGACACTGAAGACCGTCTCTGATGTGGTTAGAAAGAAGTTCATCCAACTGGCCCAGTGCAGTTTCATTGGATTCCCTAATCTTCTGAAAATAGCAAAGACTAAGATTGAAGGCATTAAGCTAAACAAAGAATCCCTGGCAGAATCTATGCTGAAAACTCAATTCAAGATGGAGCTCATCGTTTACAGCCAAGATGGCACATACAGCCAGAGTCTAAAGCATGCAAAGGATAAATTGGAGGAGATGGAAAAAGAAAGGCCACAACCGAAAATAAAACTGCCCTTACTTTCGAGTTTCGACCTTGGCACAGACAATCATGCCACCTTGCGTGAGATGAGGTTGCACCTTAAATCCTACTACACAATTGCAAGCAAGCGTCTAGCTGACCAGATCCCAATGGTGATCCGCTACATGCTGCTGCAGGAAGCTGCTTTGGAGCTGCAAAGGAACATGTTACAGCTGCTGCAAGATAAAGACGGTGTAGACAACCTGCTTAAAGAGGACTGTGACATTGGCCAAAAGCGAGAAAACTTACTGAGCCGCCAGAAACGTTTAATGAAGGCACGCAGCCTCTTGGTCACCTTTTAGAAGTTACTTTCATAGATTACTGCAACATTTTAATGCAATGAAATCGTATGCTGGTACTGAAGAAAATTATCAGCATTGACAGCAAAGAAGTAAACattcatgctgtttttttttttaaagaaatattccTTTGAGGAAACATGGTTTTTCAAAGCTACCTTTGTTATTTGAAGTGCGTCTTGACCAGTGTCAGATGCTGTATATGACTTTTGGGACATGGTATTCTTATTTAAGTACAAATTGATGAAGTGTCAGAACATTCAGTAAATTCATGTCATTTCAGTACTCtaaaaaaatatgacaatttaaTGTTTATATGTTACAACCAATGTTTCGAAAATTGATAAACTATTTAGTGCTTTGTACCAGAAATGCTgcaacagatatttttttaaataccgtTTTCgaggtataccatggtttggaaaagtcatggttttaaaaccgtcaacatTTCCTGTTATAcctttcctaaggtatgtgtaagatttttttatttacttttttttaggacaacagtatgtccagcaaaaaaatatatccaaaaataccattttaaattttaaagaaatctgtgtttttggaactaatgaagacagcagaagtcaataattcatttggaTTATTTAGCTGGACATATTTACTGAatttagatattaatatttacaaaatattttaaatgttttacaaaatattttata

Function

symbol description
mxa Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within response to arsenic-containing substance; response to bacterium; and response to virus. Predicted to be active in several cellular components, including cytoplasm; microtubule; and nucleus. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).

GO:

id name namespace
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission biological_process
GO:0098884 postsynaptic neurotransmitter receptor internalization biological_process
GO:0009615 response to virus biological_process
GO:0009617 response to bacterium biological_process
GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane biological_process
GO:0048285 organelle fission biological_process
GO:0031623 receptor internalization biological_process
GO:0061025 membrane fusion biological_process
GO:0046685 response to arsenic-containing substance biological_process
GO:0050803 regulation of synapse structure or activity biological_process
GO:0000266 mitochondrial fission biological_process
GO:0098844 postsynaptic endocytic zone membrane cellular_component
GO:0030424 axon cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0015630 microtubule cytoskeleton cellular_component
GO:0045211 postsynaptic membrane cellular_component
GO:0005634 nucleus cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0031966 mitochondrial membrane cellular_component
GO:0014069 postsynaptic density cellular_component
GO:0043197 dendritic spine cellular_component
GO:0044327 dendritic spine head cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008017 microtubule binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030721-5 Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within response to arsenic-containing substance; response to bacterium; and response to virus. Predicted to be active in several cellular components, including cytoplasm; microtubule; and nucleus. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).

Ensembl:

ensembl_id ENSDARG00000021688

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001544 True 2646 mRNA 0.41 12 7562316 7570181

Neighbor

gene id symbol gene type direction distance location
XLOC_000975 NA coding downstream 7977 7545049 ~ 7554339 (-)
XLOC_000974 CABZ01075316.1 coding downstream 420173 7142039 ~ 7142143 (-)
XLOC_000972 klf7a coding downstream 1067932 6403551 ~ 6494384 (-)
XLOC_000973 CU571320.1 coding downstream 1108797 6453404 ~ 6453519 (-)
XLOC_000971 NA coding downstream 1161990 6398199 ~ 6400326 (-)
XLOC_000977 mxb coding upstream 4170 7574351 ~ 7603734 (-)
XLOC_000978 efnb2b coding upstream 61938 7632119 ~ 7659870 (-)
XLOC_000979 arglu1b coding upstream 91910 7662091 ~ 7673376 (-)
XLOC_000980 NA coding upstream 129842 7700023 ~ 7701856 (-)
XLOC_000981 BX908756.3 coding upstream 201376 7771557 ~ 7844362 (-)
XLOC_000969 NA non-coding downstream 1388615 6159631 ~ 6173701 (-)
XLOC_000982 BX908756.2 non-coding upstream 231350 7801531 ~ 7801646 (-)
XLOC_000985 CR855320.6 non-coding upstream 349938 7920119 ~ 7920206 (-)
XLOC_000996 NA non-coding upstream 632209 8202390 ~ 8205228 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000299_04186183_04196219 MX1, MXB, MXA coding CI01000299 null 4184967 ~ 4197884 (-)