RNA id: TCONS_00000200



Basic Information


Item Value
RNA id TCONS_00000200
length 2367
RNA type mRNA
GC content 0.44
exon number 1
gene id XLOC_000107
representative True

Chromosome Information


Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 8984068 ~ 8988504 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence


ATGAGACTCGTAGGAACAATGACTGCCATAATCCTTATTATGTTCATTCTGGCTCAAGGTCTCGAGTGCTCCCAGACATGTAAATGTGATCAGATGTATTTCTGCAACTGTTCCTCAAACAACCTCCATCAGGTTCCAACAGTTCCATCAGATGTGCTTGGCCTTGACCTGTCTTTCAATCAAATTGAGTCAATCAACATGACTGATCTCAGCTCTTACAATGAGCTGATAATCCTCAACTTGCATAAGAACAAACTCAGGCATATACACAGGGATGCATTCAAGTCCCAACATAACCTGGAAGTTCTCGATCTCTccttaaacaacctgaacaatcTCTCTCCGTCTTGGTTTCACAAGTTAAAATCTCTCCAGCAACTTAACCTTGTAGGAAACCCATACTCAACTGTGGGACCTGCTCCAATCTTCAAGTCTCTTGTAAACTTGAGGACACTTCACTTAGGTAGTCCTTCACTGAGAGAGCTACACAAGAATGGCCTAGATGTGCTCACTCATCTGGACGAGATGACATTTTTTGGCAGTAACCTGAGGTCATATGAGAACGGGAGCTTGAAAGCAGCTCGTCCCATCGGTTCAGTCTCTTTGAGTCTACAGAATTTGTTTGAGAGTGATCCAGAACTAGTTTCCAAGGTCCTTCAAGATGTCTCCCACCCTGAAACTCTGCTGATAATCAAAGATGTCActatgaaaacaaacacatctaCAGAACCCTTCAAAATGGTGAAGGAAGGTGGCACTAAGAGCCTGACTTTCCAAAACTCCTCCACGACCGATCAAGCCTTGACCTCTTTTTTAGAGTTCATGGATGGCTCTCCATTGTCTTTTATTGGACTTGAAGATATACAATTTGTTGGGATAGGAGAGTGGCAGAAAGCTAAATACACACATCATGACAGCCTACGCACAGCCTACTTGCGTAATATTGAAATAGAAGGTTTCTTTGGGTTTAGCAGCATGATAGAGTTGGGATTTCTACTGAAGCACTTCCACAACGTGTCTGTGATCAATGCCACAGTGTTTGTGATTCCTAAGGAAACCACATTCCTGTTGAAAAATCTAGAATACATGGACCTCAGCCAGAATCTCCTGACAGACTTGACTATTCAACCAACACTGTATACAGGATCTGGCGCATATCAAAACCTCAACATGCTCAATGTGAGTCAGAATGTTTTAAAATCTCTCGGGCTGATGTCTAGGTTGGTCACCAATCTTAAAAAGCTCAAATATTTAGACTTAAGTTATAACAGTTTTGTTTCAATGCCAGAAAAGTGTAGCTGGCCTGTTACTCTGAGGTTTCTGAACCTTTCAAGCACAAAGTTAAGCACATTGACTCCTTGCTTGCCTTCGAGTTTGACAGTTCTGGATCTCAGCGAAAATGATCTTAAGGCGTTCAAGCAAAGATTTCCTCATCTCACTACACTTATACTGACAGGCAATCGCTTAATGAAACTGCCAGATGGGAAATTATTCCCAAGCCTAAATACATTGCTGATACAAAGGAACGCCTTACGGATGTTCAACCAAAGCTCTTTGAGGAGTTTTAAAACTCTGCTTTACTTGGAGGCAGGTGCCAACAATTTTGTGTGCTCCTGcaagtttgtttctttctttaaaaagGACGTTGAGGATTTGATCACCCTACAGGATGGCCGTCAAAATTACGTATGTAATACTCCCTTCACTCTCAGAGGTAATGCGATTGACAGTGTCAGACTGTCTGTGTTTGAGTGTTATATGATCCCTGCCGTCTCAGTGCTTTGTTTTGGGATTATCACAGCACTCGGTCTTGTTGTGTTAACCTGCCACAAGCTTCACGTCATATGGTACCTGCAGATGACTAAAGCATGGATACAAGCCAAACGGAAACCTGCTGTCGGTCGATTACCTGAAGAGCTCCGCTATGATGCTTTTGTGTCTTACAGCCAACATGACGCTGAATGGGTCGAGGAGATTCTTGTTGCTGAGCTTGAAGACACTCAGCCTtcgttttccctgtgtttgcacAAACGGGACTTCAGACCGGGCCGCTGGATCGTGGACAACATCATTGACTCAATTGAAAAGAGCTATCGAACTCTTTTTGTTCTGTCGGAGCACTTTGTGAGCAGTGAATGGTGCCGTTACGAGCTGGACTTCTCACATTTCCGCATCATGGATGAACACAATGACTCCGCTGTCCTGGTGCTTCTGGAACCAATAAAGAAGGAGACGATTCCCAAACGCTTCTGCAAGCTGAGAAAGATTATGAACTCCAGGACGTATCTGGAGTGGCCTGAGGATGAGGACAAGAGAGATGAGTTTTGGAGCAATCTGAGAGCCGCTTTACAGAGAGACGAGTGTTAA

Function


GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0002253 activation of immune response biological_process
GO:0006954 inflammatory response biological_process
GO:0050729 positive regulation of inflammatory response biological_process
GO:0034134 toll-like receptor 2 signaling pathway biological_process
GO:0002755 MyD88-dependent toll-like receptor signaling pathway biological_process
GO:0002224 toll-like receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0002237 response to molecule of bacterial origin biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0038023 signaling receptor activity molecular_function
GO:0042497 triacyl lipopeptide binding molecular_function

KEGG:

id description
ko04151 PI3K-Akt signaling pathway
ko04145 Phagosome
ko04613 Neutrophil extracellular trap formation
ko04620 Toll-like receptor signaling pathway
ko05205 Proteoglycans in cancer
ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05170 Human immunodeficiency virus 1 infection
ko05161 Hepatitis B
ko05171 Coronavirus disease - COVID-19
ko05162 Measles
ko05168 Herpes simplex virus 1 infection
ko05169 Epstein-Barr virus infection
ko05132 Salmonella infection
ko05134 Legionellosis
ko05152 Tuberculosis
ko05146 Amoebiasis
ko05144 Malaria
ko05145 Toxoplasmosis
ko05140 Leishmaniasis
ko05142 Chagas disease
ko05323 Rheumatoid arthritis
ko05321 Inflammatory bowel disease
ko05417 Lipid and atherosclerosis
ko04131 Membrane trafficking
ko04147 Exosome
ko04054 Pattern recognition receptors
ko04090 CD molecules
ko00536 Glycosaminoglycan binding proteins

ZFIN:

id description
ZDB-GENE-040219-6 Predicted to enable signaling receptor activity and triacyl lipopeptide binding activity. Acts upstream of or within activation of immune response and immune response. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; integument; liver; and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2).

Ensembl:

ensembl_id ENSDART00000055006

JBrowse2


Neighbor


RNA id RNA type direction distance location representative gene id
TCONS_00003031 lncRNA upstream 9716 8967479 ~ 8976422 (+) True XLOC_000106
TCONS_00003029 lncRNA upstream 20199 8950874 ~ 8965939 (+) False XLOC_000105
TCONS_00000198 lncRNA upstream 20199 8950874 ~ 8965939 (+) False XLOC_000105
TCONS_00003030 lncRNA upstream 20199 8961004 ~ 8965939 (+) True XLOC_000105
TCONS_00000197 lncRNA upstream 287027 8694291 ~ 8699111 (+) True XLOC_000104
TCONS_00003032 lncRNA downstream 140882 9129386 ~ 9132490 (+) True XLOC_000111
TCONS_00003033 lncRNA downstream 165590 9154094 ~ 9155521 (+) False XLOC_000113
TCONS_00000210 lncRNA downstream 168872 9157376 ~ 9161475 (+) True XLOC_000113
TCONS_00000214 lncRNA downstream 289342 9277846 ~ 9285351 (+) True XLOC_000116
TCONS_00000220 lncRNA downstream 898451 9886955 ~ 9914630 (+) False XLOC_000120
TCONS_00000196 mRNA upstream 283454 8694196 ~ 8702684 (+) False XLOC_000104
TCONS_00000195 mRNA upstream 315652 8662530 ~ 8670486 (+) True XLOC_000103
TCONS_00000194 mRNA upstream 375574 8601935 ~ 8610564 (+) True XLOC_000102
TCONS_00000193 mRNA upstream 389123 8593560 ~ 8597015 (+) True XLOC_000101
TCONS_00000191 mRNA upstream 400072 8579197 ~ 8586066 (+) True XLOC_000099
TCONS_00000201 mRNA downstream 16215 9004719 ~ 9064912 (+) False XLOC_000108
TCONS_00000202 mRNA downstream 16248 9004752 ~ 9044347 (+) True XLOC_000108
TCONS_00000203 mRNA downstream 82820 9071324 ~ 9074479 (+) True XLOC_000109
TCONS_00000204 mRNA downstream 93913 9082417 ~ 9091659 (+) False XLOC_000110
TCONS_00000205 mRNA downstream 98438 9086942 ~ 9091935 (+) True XLOC_000110
TCONS_00000154 other upstream 1922195 7063837 ~ 7063943 (+) True XLOC_000081
TCONS_00000149 other upstream 2198334 6787690 ~ 6787804 (+) True XLOC_000078
TCONS_00000134 other upstream 2800606 6182342 ~ 6185532 (+) False XLOC_000067
TCONS_00000123 other upstream 3484054 5497285 ~ 5502084 (+) True XLOC_000062
TCONS_00000121 other upstream 3535694 5438743 ~ 5450444 (+) False XLOC_000062
TCONS_00000208 other downstream 165590 9154094 ~ 9155273 (+) False XLOC_000113
TCONS_00000209 other downstream 166489 9154993 ~ 9155521 (+) False XLOC_000113
TCONS_00000213 other downstream 230144 9218648 ~ 9221616 (+) True XLOC_000115
TCONS_00000230 other downstream 1063270 10051774 ~ 10054771 (+) False XLOC_000126
TCONS_00000231 other downstream 1063280 10051784 ~ 10058057 (+) False XLOC_000126

Expression Profile


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