RNA id: TCONS_00050139



Basic Information


Item Value
RNA id TCONS_00050139
length 4898
RNA type mRNA
GC content 0.35
exon number 6
gene id XLOC_025415
representative False

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 29510818 ~ 29544039 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence


GTCGCCCTCTTGTGGACTGTCACCCATAACGCTTTGACACAGAGCGCGTGCATGTTACTGCCTTTAAGTTAATACTTCCTCATATACACAGACACGTCCAAAACTGTCACAACcacatgagtgagtgagtgagtgagagagagggaaagagagagactgAACCAATCTGTTTCCTGTATTACAACTTAGTTCCTTAACAGTTGTTTTACAGCGGTAGCCGGCAGATTTTTTAAAGTATCGAAAATGCAAGCAATAAAGTGTGTGGTGGTCGGAGATGGAGCTGTGGGAAAGACCTGTCTTCTCATCAGCTACACTACCAATGCGTTCCCCGGGGAGTACATTCCCACAGTgttTGATAACTACTCTGCAAATGTAATGGTGGATAGCAAACCAGTCAACCTGGGACTCTGGGATACAGCCGGACAGGAAGATTATGACAGACTGCGGCCACTCTCCTACCCGCAGACGGATGTGTTTCTTATCTGTTTCTCTTTGGTGAGCCCAGCATCATTCGAAAATGTCAGAGCCAAGTGGTACCCAGAGGTGAGGCATCACTGCCCTTCCACTCCAATTATCCTGGTTGGCACCAAGCTTGACTTGAGAGATGAGAAGGAGACCATCGAGAAGCTGAAGGAGAAGAAACTGGCACCGATCACTTACCCACAGGGTCTCGCATTGGCCAAAGAAATAGATGCAGTAAAATACCTGGAGTGTTCGGCCCTCACTCAGAGAGGGCTAAAAACAGTGTTTGATGAGGCGATTCGCGCTGTGCTCTGCCCACAGCCCACCAAGGTCAAGAAGAAGGGCTGCGTGATGCTCTAAAGATACACGGTACATGTTTGTGCATATGGGTTGTTGGAGTAATGTTGTATTTTCACTGTCACACATGAATATCATTAGTAATGTCATTAATCATTAGTAATGCAGTAAAAGATTGAACACTTGTGTCTTTTATGTACCCCTTGCTATATAAACTGCTGTGTTGATACATTTTTTAGTCAAATATCAAAGAATACACTTAAAAACTATTTGTTgcttgtttaagctacttatttgaaatgagctgaattaacaaaattcttgagttttttgggataacgtaattgttttatgctcaatccacttatacttgtaaaacaattaagttaactgaatcgatttgtgttgggacaactggAGGGAAttctgtggaacccagcattttttacaatggTGTGTCTTCTTTAGCAATGCAGCCAATGCTACACATTAAGGGCCCTATAGTACACTGCGCAATAAgccgcaagacgtgtttggtgctatttgttgctattttcagaataGCACAGTAAGTTTTGtgacatgttgtttaaatagtaaatccatttgcaccactttgtggactcattggTGTGccagtctaaaaaggaggtgtgttaaggtgcattgttggagcgttgctattttaaggaactgaaaAGACTGCGCCATTGATccactaaaagctggtctaaagacagcaatacacaaatatctttacatatgaaaagaattaaaggattaaaatgttacaaaaataattttttatagaaatataaaaactaaatgtaaaaaataaaataaattacataaaataaataattctacattataaaaatattaatattaaaacaaatatacaataaacaaagataaatataaaaaacactacctTGATGCCTcatatcaagtttttttttttagttgattcatgacaatttgcatttgtgtaatgttattattattagcattattaattttttaagcatgtttatatttgttttaataaaaacaagtttagatttgtccacctgttggagacgtctgcatcaccatatgggcataagaataggacgtgcgTTTGGAATAACTCGACCactttgaccacactttgttattattgttcatttattggtttACTGGTGTTAtgtccttttagatgttaatatttaaCTAGGATTAGATGACATAACATACaatagtttaatgtgtgtgaaaagcagatggagaaagaaataaactgaaaaccaaatatcactgcaattatttattgcccatatatccaatgaaaccagtgaaaatatattatacagtgaaagaaaatatttacaatgattaaataatgaattacctgGGGGGAGAGGAAGTTGCTGAATatgcttaaatcaaagaaataaatataacaaaactcagtaactgtttccaccaaactaaactaaatatgaaaataaaagcatgaaaagaaacatcttcaacgtaccaaacgtcttaactaaacatacagaaaacagcacattctcctgaacctaaTAAACTAATACAACAGatttagaattgaatttagaaatagttttaaaacaaatatttgcgcttaacaaacgtaaATTGCGTACAACAGCGTTTTCTTATCCACGAAAGCAGTAAAGAGTAAAactaaagtaaagagaaagtaaaaaggtCGAATAAAGGAGGAGGCTTCTTTATCCTTGCTGgaaatggtctgtttaactgttcttGCTAGTGAACCGCTCAgtttttccattcagtttttcctattataaagtccgccatgtaaatagctaaATGTGTGATGCAGCTGATTCTTAAAGGGATCAAAAGACGAGACTTAATgactggtttaatgcacgttatgctcaaagcacacacacacataaaaaaaaagagaataagcacaaccctgttagaccatgcgccatttTCTGTCCCTAAAAcaacaaaagtggattcagacacgtccttaatgcttttgtgctatGCGCTTTAGACACtacacctagattgttaaaatagagcccataggcTTCTATCCAATGGCAAAATTGCAGCCTTAGTCCCTGGTTAGGCTTTTTGTACACTAAAACAGTACTTAAACTATCTctacatacatataaaatacattatcagTACAAGAAAGGAGAGAAAACTGCATGAAAATCAGTGTTCACAAACCAGGTTTAGTTTAAACATGTCAACATTTTGAGTatgttgttacattttattattgaaaaCCTTCCGGTGTGACACTTTATACTAATTTCGGTTGTTCAGAAAACTTTATTTAAGGACCACATTCAAGATCATCTGACTGAAGTGTCTCATAACTTTttacatatttaacttttttggaaCCATTATGTAATTAAGTTTTGTTGTCCTTTTGTGTGATTTATTGAATATATCCAACAAGTctcgaaaagaaaaaaatatttaaataaatatatgacaATAAGTGTCCAAACAATGAGGCTAATCACTTTCATGCTATATGTGCCATTTTGAgcagattttattaatttattattattattattattttgctgtcACACCATAggacatatttaaaatacagttttgtaaaaatgcaaaatcaacaaccaaaaaacaacaaaggagGTTAGTGACCTCTTATATTTACAAAAGTAATTGCTGCCTATTTGTCAACTACCCATGTGGTTAGATTGAAAAATGTCAGAGAGGAAGAAGTTCATGAAAAAATGTCAGACGTCATCTCAATTACAGCGAACGGCTTTTGTTCTGTTGCTGCTTTGCAATTGTTGCAACTTACAACCACGCTTTCAGGTGGAAGTTAAAGACAGTAATTTTGATTTGGgccattcttaaaaaaaaaaaaaaaggatgtgtGGAGATGCAAAAGTAGAACATCTACTGACCTTTTGTTATTTCTGCCTCCAGATTCGtcactgtaaaaaagaaaaaggtacCAGAGGAATCAACTGGTTTTCTCCTATAAACCAACACAACATGCAATTGCCTTACGAAAGCTTTTCCTCAATTTTTAGCTGAATATATCTTTTGAACATGCCACATTGATGCCGATACAGTGATAATGTTAGTAACAgaatatttaatcatattttaacTGATGTGTTATGTTATATTGAGACTGGAGTGTGTTTGTCAGGTACGCAGTTGCATATTGTTTTCTAGCGACAACATAAACagctgaattttttatttttttgttacacaTAATTGAACCCACAGGAAGGTATTAGACATGAATCATATTCATGTTATACGTATGGAATTATTTTTGGCagaaaatggcaaaaataaacTGTACAACTGTTTCCagatgcttgtgtttttttttttttatcttcatcCACCTGAACAATCTTTTTTTGCTACTCATAACACGTACAGTATATTGAGGCCAGACAGCTTCAAGTAAATGAATTTTGTAACGCTTTGTGACGAAGACCTTTGATTTATGTCCTCCAAGGTGGCACTTACAGTGTGTGTTGCTCAGAATACAATGCATATTGCTGTTTTGAatctcttttttatatatatctgtagcacttttataatgtagattgtgttatgATCTCTAGAGGTTAAGCAGTAACAGAAATGGGTTGGTTATTATGTGAGTGAGAAAATATGAATGGAATGAAACAATTGTATAAAGAATGCTTCGAACCACAGAGATATGGACAAAGTCAAAacaatttattgatttgtttagaaatcacaaataaataaacacacattttcttaaataactttaacacaaataaaagtacattaaaaaagggagcgattggtccatattttaaatttctatacagagaggtcatgttttgatcttcaattggttTTAGGCAGTCATGTGGTGCGATTTGCAGGTCACCAAGCTTTAACTTTGCAACATTGAATTTTGTTGCATGGGCTTGTGTTTgtgtctatggggagaaaagtgcagtgtgaccacggTAACTCCCTTAtcaaaaaacaatacaaactaatatgaaataaaatgtctTCAAGAGCCCTACTTCtcttaaattgacaaaaaaaaacacagtatatacactataaaaatgtttttccaa

Function


GO:

id name namespace
GO:1905517 macrophage migration biological_process
GO:0032878 regulation of establishment or maintenance of cell polarity biological_process
GO:0042742 defense response to bacterium biological_process
GO:1902622 regulation of neutrophil migration biological_process
GO:0090022 regulation of neutrophil chemotaxis biological_process
GO:0001780 neutrophil homeostasis biological_process
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0009611 response to wounding biological_process
GO:0048246 macrophage chemotaxis biological_process
GO:0043652 engulfment of apoptotic cell biological_process
GO:0032956 regulation of actin cytoskeleton organization biological_process
GO:0007015 actin filament organization biological_process
GO:0002685 regulation of leukocyte migration biological_process
GO:0016601 Rac protein signal transduction biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0030865 cortical cytoskeleton organization biological_process
GO:0030031 cell projection assembly biological_process
GO:0002446 neutrophil mediated immunity biological_process
GO:0030036 actin cytoskeleton organization biological_process
GO:0008045 motor neuron axon guidance biological_process
GO:1990266 neutrophil migration biological_process
GO:0008360 regulation of cell shape biological_process
GO:0050832 defense response to fungus biological_process
GO:0007163 establishment or maintenance of cell polarity biological_process
GO:2000391 positive regulation of neutrophil extravasation biological_process
GO:0042995 cell projection cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005938 cell cortex cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0031982 vesicle cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0019901 protein kinase binding molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04014 Ras signaling pathway
ko04015 Rap1 signaling pathway
ko04310 Wnt signaling pathway
ko04370 VEGF signaling pathway
ko04071 Sphingolipid signaling pathway
ko04024 cAMP signaling pathway
ko04510 Focal adhesion
ko04520 Adherens junction
ko04810 Regulation of actin cytoskeleton
ko04613 Neutrophil extracellular trap formation
ko04650 Natural killer cell mediated cytotoxicity
ko04662 B cell receptor signaling pathway
ko04664 Fc epsilon RI signaling pathway
ko04666 Fc gamma R-mediated phagocytosis
ko04670 Leukocyte transendothelial migration
ko04062 Chemokine signaling pathway
ko04360 Axon guidance
ko05200 Pathways in cancer
ko05231 Choline metabolism in cancer
ko05210 Colorectal cancer
ko05212 Pancreatic cancer
ko05170 Human immunodeficiency virus 1 infection
ko05163 Human cytomegalovirus infection
ko05135 Yersinia infection
ko05020 Prion disease
ko05418 Fluid shear stress and atherosclerosis
ko05415 Diabetic cardiomyopathy
ko05416 Viral myocarditis
ko04031 GTP-binding proteins

ZFIN:

id description
ZDB-GENE-040625-27 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within several processes, including defense response to other organism; leukocyte chemotaxis; and regulation of neutrophil migration. Located in cytoplasm. Is expressed in neutrophil and thymus. Human ortholog(s) of this gene implicated in immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis; immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia; and immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia. Orthologous to human RAC2 (Rac family small GTPase 2).

Ensembl:

ensembl_id ENSDART00000193743

JBrowse2


Neighbor


RNA id RNA type direction distance location representative gene id
TCONS_00050132 lncRNA upstream 100859 29406013 ~ 29409959 (+) True XLOC_025412
TCONS_00052695 lncRNA upstream 112667 29393465 ~ 29398151 (+) True XLOC_025411
TCONS_00052345 lncRNA upstream 584743 28899129 ~ 28926075 (+) True XLOC_025406
TCONS_00050122 lncRNA upstream 667642 28842122 ~ 28843176 (+) True XLOC_025404
TCONS_00052694 lncRNA upstream 727061 28765693 ~ 28783757 (+) True XLOC_025403
TCONS_00052696 lncRNA downstream 95945 29639984 ~ 29640294 (+) True XLOC_025417
TCONS_00050149 lncRNA downstream 120318 29664357 ~ 29671653 (+) False XLOC_025419
TCONS_00052697 lncRNA downstream 125034 29669073 ~ 29669897 (+) True XLOC_025419
TCONS_00052698 lncRNA downstream 143510 29687549 ~ 29710222 (+) False XLOC_025420
TCONS_00052700 lncRNA downstream 143516 29687555 ~ 29699638 (+) False XLOC_025420
TCONS_00050137 mRNA upstream 24320 29476085 ~ 29486498 (+) False XLOC_025414
TCONS_00050136 mRNA upstream 24320 29476085 ~ 29486498 (+) True XLOC_025414
TCONS_00050135 mRNA upstream 26927 29469283 ~ 29483891 (+) False XLOC_025414
TCONS_00050133 mRNA upstream 41959 29445473 ~ 29468859 (+) False XLOC_025413
TCONS_00050134 mRNA upstream 42787 29458517 ~ 29468031 (+) True XLOC_025413
TCONS_00050141 mRNA downstream 56878 29600917 ~ 29602479 (+) True XLOC_025416
TCONS_00050142 mRNA downstream 96798 29640837 ~ 29654923 (+) False XLOC_025418
TCONS_00050144 mRNA downstream 96957 29640996 ~ 29654922 (+) False XLOC_025418
TCONS_00050145 mRNA downstream 97142 29641181 ~ 29642116 (+) False XLOC_025418
TCONS_00050151 mRNA downstream 170736 29714775 ~ 29845175 (+) True XLOC_025421
TCONS_00050129 other upstream 343671 29167020 ~ 29167147 (+) True XLOC_025410
TCONS_00050124 other upstream 644736 28861176 ~ 28866082 (+) True XLOC_025405
TCONS_00050119 other upstream 660384 28831518 ~ 28850434 (+) False XLOC_025404
TCONS_00050090 other upstream 2103607 27407096 ~ 27407211 (+) True XLOC_025392
TCONS_00050085 other upstream 2436686 27071773 ~ 27074132 (+) True XLOC_025389
TCONS_00050143 other downstream 96955 29640994 ~ 29654697 (+) False XLOC_025418
TCONS_00050146 other downstream 98161 29642200 ~ 29654921 (+) False XLOC_025418
TCONS_00050147 other downstream 104083 29648122 ~ 29649158 (+) False XLOC_025418
TCONS_00050148 other downstream 110121 29654160 ~ 29654925 (+) True XLOC_025418
TCONS_00050160 other downstream 704700 30248739 ~ 30249036 (+) True XLOC_025429

Expression Profile


//