RNA id: TCONS_00062974


Basic Information

Item Value
RNA id TCONS_00062974
length 3007
RNA type mRNA
GC content 0.40
exon number 6
gene id XLOC_032243
representative False

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 40992409 ~ 41009381 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence

CCCAGCAGTGCACTCCTCTTTTAACTCGCGCGCGCGCACGCAAAGCAGAAGGATGTTCAGGGTGTGGAGAGTCCTGCGCTCTGAGTAATCTATAAAGCAGTTCTCTACTTAACCATATTTCACCCCTGTTTTACCATCTTTAACATCATGGTGAATTAGAAATAAATAGTTAGCGTTTCATATGACGTCAACAGAAAGACGACGTTGCTCAAGTTTGACGTCAAGTTCAAAATACCTGGATCGACGCATGGCGTCTTGTGTCGAGTAGGCGACATGGAACTATGAAGAAAGACGTTCAGAGTTTTAATATGGAAATCAGATTTCTGACCAGTGCAACGGACGGTCAGTAATAACTACTACTAGCCAATCTCAGGAAAACGCGCGTGCCTTCATCTTTATTGGCAaagataaatgttttaatataaaagaCGACGCTGAGAATCTTTCATCAACAACTCACCCAAACGCCTTATAATGATGTATCGTGCTTTTTGGGATACAATATTCCTTCTCACCGGCTCCCTTTTTACGTATGGGCAGGTGCAAGAGAATTCTACCTCAACGACGACTATTGCAACCAcgacaacaactactacaacaactaccaCCACTACCACCACCAGCACCACGACCACCACTACTACCACACGAGTCAGAAAATTTATAGCAGCTGCAGTCCACTCTCACTTTGATGACTGTCCCGACTCCCACAGCCACTTCTGTTTTCATGGCACATGTCGTTTTCTCATCCTGGAGGAAACACCTGCATGTGTatGCCATCCTGGCTTTGTGGGCATGCGGTGTGAACATGCAGATCTCCTAGCAGTGGTGGCATCAAACCACCGGCAGCAGACCGTGGCCACCATGCTGGTGTTGTGTGTGGTGGGCAGTGTCATGCTCATGCTGATCTGCACTTTACTTAaTTGTTGGTGGAGACGGGGTGGTTGTGGGCGAGGTCACACCCTCTCCTGTTGGACGGAGAAGCCTAGGAGTATTTTGACGAGTGGGACATCCTGCTGTAACTCAGAAACAGTGGTTTGACGCAGGTTTTCTGGAGCTCACTCAGGTGCcctcttaaaacaaaaaaagacagcaaCATCTTCCACCTTGCTCCTGGACTTTACAATGACTGCGTTTCCTAAGCTACAGACTTGCAGAGCTGGTAAGCGCAGCACATGTTCAATATGGGCAGTGGGAGAACTCGAGCAAACATGGGACTTTTATATTCAGAGAGACTGAGTAGTTCCAAAAAGAAGATTGTTGGAACAGTAACTGCTAATGATGGAACTCAAAAGCTCGGAATGGAAAAATCTGAACAAAATGGAACTCGACTACAGAAGATACTCGGCCATTTTGGGGAAAAGATATGGATCTGTGGCTTAAACGAGAGTGAAAAACTTTGAGAGAGGTTTTAACGAAATCATTCTTACTAACAGAGCTTATCTTAAAGCTTTATAGTGTATGTATTAGACAACATTCTCCCagtctttgttttttaaatactcaATATATCAAAACACACTTATAATCTGCCGTTAATGGGATGTGAaactcactttaaaaaaatcGTTTTTATTAAGGATATATCATCACATTCTTTTCTCTATCACGTTACGGCTAAAGAATGGGAGATTTCTTTTCTTACCATTTAAGTCAGTTAAGCAGTTAGTAATACTACAGAATATTTTgccaatttattttaacttaatctCTTTATAATGCTGATTTAAAGACGAAAAACAAAGTGTAACAGCTAACATGAGAGACCAGAGCTTTGAGGGACAAATCCTACTTCTGACACGTTATTCTTTAACACTTTTTATCTGAATGgagtttcatttttttatgtgcgttttaaaatctaaatattggtGAACAAGTCACAATTATGACATGTAACTTGACAAGTTATGCATAGATTCACGAATCCCACACAAGATTTTCTTCACCTAATGTGCTTTCAAAGATTTCTCAACATCTCTAAATGCTTTGGAAATGGATCCTCTGTATGCGCACTATTTTTGAAGCGTCACATGATATCTGCATGTTCACACTGAATGCATGCGTGTTTGAGCACATAATTACACACAATGCACTTTTGCGGTGTAGATTTCCACCTCACTGTTAATACAAACCACCTTCAAATCTGCACTTTAGATCCTTTTCCATTATAGGCGTCACTCACTCACAATTGTAAGCATACAGAGGCGCAGATCCACGATATAAGCAATCATAATGGATGATGTTCAGTTTGATGCACGTTGTATTATGCAAGATATATAGAAGCTTTTACACTGAAATGTTTTAAACCGTGTTCATTTTGCTTTCTTTTCTAATCTTATCTGTCCCTAAGCTTTTGCCAATGACCTCATGTTATAAAAAGATGTTCGACTGACCCCTTTGTAAGGTATTTGCTCTTTTAGGGTCAGAGATATTTATATTGATATGTTAAAATGAGGTGCTGGTACATATATAAAGTAACCACTGTGGGTTGCATTCATACAAAACCCTTCTCAAGCTGGTAAGTGGCTGATATAGcgcttaaaaaaaaagataaatattgataaaaatactaataatttgaTCAGATTAATGATCTGACTGTTCTGGCATCAGATCATGAAGGAAATATGTGATGTTATTGTGTGaagattcatttaaaaatgtgatcTAATGCCCTAGTGAGTTGAAGAGGATTCATCTAGGTGGCTTTTTTGAGTTATCAAGTCTTTAAATGATTTTGATCAGCCTGAAAAAACTGGTTCAAATGGTTTATGATCTAGTTGGCTGACCCTGATATGTGACTTAAAGGAAACATTCACTCAAAAACACTCATTTGcagttcatttattcactttttgaTCAATCCAAAATGTAATGTAggatgtaaaaaatgttttacagtctTTGGTGATTCATAGTGAATGGCTACTAGTGCTTTGAGAGTCTAACGCATAAAgcacaggtctcaaactcaattcctggagagccgcagctctgcacagtt

Function

GO:

id name namespace
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity biological_process
GO:0045840 positive regulation of mitotic nuclear division biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0005615 extracellular space cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005154 epidermal growth factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04012 ErbB signaling pathway
ko04014 Ras signaling pathway
ko04151 PI3K-Akt signaling pathway
ko04915 Estrogen signaling pathway
ko05200 Pathways in cancer
ko05210 Colorectal cancer
ko05212 Pancreatic cancer
ko05225 Hepatocellular carcinoma
ko05214 Glioma
ko05211 Renal cell carcinoma
ko05215 Prostate cancer
ko05223 Non-small cell lung cancer
ko01521 EGFR tyrosine kinase inhibitor resistance

ZFIN:

id description
ZDB-GENE-040724-208 Predicted to enable epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of epidermal growth factor-activated receptor activity; and positive regulation of mitotic nuclear division. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in diencephalon; midbrain; retina; and third ventricle. Human ortholog(s) of this gene implicated in gastroenteritis and pancreatic cancer. Orthologous to human TGFA (transforming growth factor alpha).

Ensembl:

ensembl_id ENSDART00000151419

JBrowse2

Neighbor

RNA id RNA type direction distance location representative gene id
TCONS_00064921 lncRNA upstream 6274 40984597 ~ 40986135 (+) True XLOC_032242
TCONS_00062966 lncRNA upstream 151508 40837650 ~ 40840901 (+) True XLOC_032238
TCONS_00062958 lncRNA upstream 328092 40662533 ~ 40664317 (+) True XLOC_032232
TCONS_00064919 lncRNA upstream 336363 40652905 ~ 40656046 (+) False XLOC_032231
TCONS_00064920 lncRNA upstream 338263 40652920 ~ 40654146 (+) True XLOC_032231
TCONS_00064922 lncRNA downstream 71129 41080510 ~ 41082985 (+) True XLOC_032245
TCONS_00062980 lncRNA downstream 86792 41096173 ~ 41102304 (+) False XLOC_032246
TCONS_00063001 lncRNA downstream 495734 41505115 ~ 41505986 (+) True XLOC_032258
TCONS_00063004 lncRNA downstream 624688 41634069 ~ 41648856 (+) False XLOC_032259
TCONS_00063005 lncRNA downstream 624798 41634179 ~ 41670341 (+) False XLOC_032259
TCONS_00062972 mRNA upstream 24089 40951227 ~ 40968320 (+) False XLOC_032241
TCONS_00062973 mRNA upstream 28255 40952031 ~ 40964154 (+) True XLOC_032241
TCONS_00062968 mRNA upstream 44738 40922572 ~ 40947671 (+) False XLOC_032240
TCONS_00062970 mRNA upstream 44738 40922672 ~ 40947671 (+) False XLOC_032240
TCONS_00062969 mRNA upstream 44771 40922672 ~ 40947638 (+) False XLOC_032240
TCONS_00062976 mRNA downstream 29376 41038757 ~ 41057368 (+) False XLOC_032244
TCONS_00062977 mRNA downstream 29785 41039166 ~ 41048912 (+) False XLOC_032244
TCONS_00062978 mRNA downstream 30654 41040035 ~ 41060423 (+) True XLOC_032244
TCONS_00062979 mRNA downstream 86677 41096058 ~ 41116053 (+) False XLOC_032246
TCONS_00062981 mRNA downstream 90406 41099787 ~ 41117242 (+) True XLOC_032246
TCONS_00062945 other upstream 445434 40545865 ~ 40546975 (+) False XLOC_032225
TCONS_00062936 other upstream 942964 40043615 ~ 40049445 (+) True XLOC_032217
TCONS_00062919 other upstream 1620534 39370620 ~ 39371875 (+) True XLOC_032204
TCONS_00062894 other upstream 2134107 38845676 ~ 38858302 (+) False XLOC_032191
TCONS_00062893 other upstream 2210251 38773418 ~ 38782158 (+) True XLOC_032190
TCONS_00062987 other downstream 185306 41194687 ~ 41194801 (+) True XLOC_032251
TCONS_00062995 other downstream 445410 41454791 ~ 41454873 (+) True XLOC_032256
TCONS_00062996 other downstream 454404 41463785 ~ 41493470 (+) False XLOC_032257
TCONS_00063008 other downstream 843991 41853372 ~ 41869189 (+) True XLOC_032262
TCONS_00063013 other downstream 988582 41997963 ~ 41998096 (+) True XLOC_032265

Expression Profile

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