RNA id: XM_039796413.1


Basic Information

Item Value
RNA id XM_039796413.1
length 10261
RNA type mRNA
GC content 0.45
exon number 26
gene id slc12a5a
representative True

Chromosome Information

Item Value
chromosome id NC_053115.1
NCBI id CM020912.1
chromosome length 44863486
location 25208156 ~ 25310553 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome
species eurasian perch
(Perca fluviatilis)

Sequence

TTCCACAATCACCTCTCTGTCTGACAGCCGCGATGagaagagggaggcagggaggggaGAAATAGATGGAGAAGAAATCACACTACTGCTTCAATATGCAATCAGTTTGGCAGCTACAGTGACTGAGCAACATCATCTTGAGCAGGGGAGAGggagttttttttgtatctgtgaGTGGGAGAGAATGAGATCAGGAGTgagaaaggcaaaaaaaaaagagacagagagaaggaaaaaggaggagggagagagcaaGTGTGCAGCTTTGAGGCGTTCCATCATCCACCAAACTCCTGCAGCTtccctcttccctcctcctcctcctcctggagagagagacagagcaacagagagaagagtgtgagagagagagagagagagagagagagagagaaagaaagatagagggagcaacagagagagagcaagagagtcAGGCTTACAAGCCAGCGGAGAAGAGACGTCAAGAGGAGGATCtacagagggagaaaaaaaatccttctctctcttctgctgCCTCTCTTCGCGCATCCTACGGGCAGCGAGGAGCGAGGAGGATCCGGCTGGCATATTTTCTACGCTGCTTCCCCGTGATTTCTGTGGCTGTATCACAGTGGGTGGAGCGCAGGGAGAGCCGCCGAGAGCTCGATCGGTGACACCGCTCCGCAGCAGAAGAGTACTGTAGAAGAGCCGGGATGCTTAACAACCTGACCGACACAGAGGAGGGGGACGGGGGAGCGCAAAGCCAGGGTGACAGTAACCCCAAGGAGAACAGCCCCTTCATCAACAGCAGTGATGCTGCCGAAGAGAAGACCCAGCAGTATGACGGCAAGAACATGGCCTTGTTTGAGGAGGAGATGGACACCAGTCCTATGGTGGCGTCTCTTCTCAGCAGCCTGGCCAACTACTCCAACCTGCCACAAGGTAGCAAGGAGCACGAGGAGGCCGAGAACAACGAGGCTGAGTCATCGCGCAAGAAACCCGTCAAGGCCCCCGCGCTCGGCACTCTGATGGGCGTCTACCTGCCGTGCATCCAGAACATCTTCGGAGTGATCCTCTTCCTCAGGATGACCTGGTTGGTGGGAATCGGAGGTGTCATTGGGACCTTCTTCATAGTCTTCATGTGCTGTACCACAACCATGCTGACTGCCATCTCGATGAGTGCCATCGCTACCAATGGAGTAGTGCCAGctgGAGGCTCCTACTACATGATATCCCGTTCACTGGGCCCTGAGTTTGGGGGAGCAGTGGGGATCTGTTTCTATCTGGGGACAACCTTCGCTGGAGCGATGTACATCCTGGGGGCCATTGAGCTCCTCCTGATCTACATAGCACCCAAAGCGGCCATCTTTCCCCTGGAGGGCCTTGAGGGTGCCGAAGCAGAGGCTGCCCTGCTGAACAACATGCGTGTGTACGGCACCATCCTGTTGATCTCCATGGCCACGGTGGTGTTTGTGGGCGTGAAGTACGTCAACAAGCTGGCCCTGGTGTTTCTGGCCTGCGTCATTCTCTCCATCCTGGCCGTCTACGCCGGGGTCATCAAGACCGGCATCGACGCTCCCGAATTCCCCGTGTGTATCTTGGGCAACCGCACTTTGGTGTGGAAGTCCTTCGATGTGTGTGCCAAGACCGTTGAGACAGCTAATGGGACAGTCACCACCCAGCTGTGGCGCATATTCTGTGACTCACCTTTCCTCAACGCTACCTGCGACAAGTACTTTACAGCCAACAATGTGTCTCAGATCCAGGGCATCCCAGGGGTCACCAGTGGAATCCTGGCAGACAATCTGTTTGGGACTTACTATGAGAAGGGGGATCTGATTGCCAAAAAGTTCACAGAGTCAGCGGAAGACCAGGATGACCCTCTGACCAACGCCAACCGCTACGTGTTGGCCGACATCACCAGCTTCTTTACATTGCTGGTCGGCATCTACTTCCCCTCTGTGACAGGTATCATGGCTGGCTCCAACCGCTCCGGAGACCTGCGTGATGCCCAGAAGTCAATCCCCGTTGGAACCATTGCAGCTATCTGCACCACCTCTTTCGTCTGTATCCTCTCAATACTGCCCTCTGGGTATTGCATTCAACCTTGTCCCATTTCCTTAAGGTTTGGAGAGGGAGTCCACGGGAATTTGGTGATTGGCACGTTGGCTTGGCCGTCACCATGGGTGATCGTGATTGGCTCCTTCTTCTCCACCTGCGGGGCAGGGCTGCAGAGTTTGACAGGAGCTCCTCGTCTCATGCAGGCAATCGCCAAGGACGGCATCGTGCCCGCCCTTCGGATATTTGGCCATGGAAAGGCCAACGGAGAACCCACATGGTCCCTGCTGCTGACAGCTTGTATCTGCGAGATCGGCATCCTCATTGCTTCCCTGGATGCAGTGGCTCCCATCCTCTCCATGTTTTTCCTGATGTGCTACATGTTTGTGAACTTGGCCTGTGCTCTGCAGACACTGCTAAGGACTCCAAACTGGAGGCCCCGCTTCAAGTTCTACCACTGgGCTTTGTCCTTCCTGGGGATGAGCTTGTGTCTCACTCTGATGTTCCTCTGCTCCTGGTACTACGCCATCGTCGCCATGGTTATTGCCGGCTCTATCTACAAGTATATCGAGTTTGCAGGTGCGGAGAAAGAGTGGGGTGATGGGATACGAGGTGTGTCTCTGAGCGCTGCACGTTACGCTCTCATGCGGCTGGAGGAAGGTCCACCGCACACCAAGAACTGGAGGCCCCAGTTGCTGACGCTGGTTAGTACAGACGCAGAGCAAAACGTGGAGCAGCCTCGTCTGCTCTCTCTGACCAACCAGCTGAAGGCAGGCAAAGGTCTGACCATTGTTGGAACAGCTCTAGAGGGCACCTACCTGGAGAACAGCGAGCAGAGCCAGCGTGCAGAGAAGGCGCTGCGCAAACTGATGGAGACTGAGAAGGTGAAGGGCTTCTGTCAAGTGACCGTGTCCTCGAACCTGCGTGATGCCACCTCCCACCTCCTCCAGGCCAGTGGGCTAGGAGGCCTGAAACATAACGCTGTGCTGGTATCCTGGCCACGCAACTGGAGGCAGGGAGACGAGCACCAGACCTGGAGAAACTTTGTTGAGTTGGTCAGAGAAACCACCGCCGCTCACCTGGCTCTGCTTGTCCCGAAGAACATCTCGGCCTTCCCGTCCAATGGAGAGCGCTTCACTGAGGGTCACATCGACGTGTGGTGGATTGTCCACGATGGAGGCATGCTGATGCTGCTGCCCTTCCTTCTCCGCCAGCACAAGGTTTGGAGGAAGTGCAAGATGCGCATCTTCACTGTGGCCCAGTTGGACGACAACAGCATCCAGATGAAAAAAGACCTGACCACATTCCTCTATCATCTCCGTATTGACGCCATGGTGGAAGTTGTAGAAATGCATGACAGTGACATCTCAGCCTACACTTACGAGAAGACCCTGGTGATGGAACAACGGTCGCAGATGCTTAAACAGATCAACCTGAGCAAGAATGAGCGTGAGAGAGAGATCCAGAGTATCACTGATTCATCCCGCGGGTCAATCCGCCGTAAGAACCCGGCCGCCGTGACAACCCAGCTGAGTGTGACCGAGGACCCGCCAGCCGCCAGCAAGGAGGAGAAGCCTGAGGAAGAGTCAAAGTCGGCCTCTTCCCCTGTGTCCCCCCCCGCCCAGGTCCAGCTCATCCACGACAACACCACCCCAACCAGCCCCGCAACCCCGGCCACCCCGCTGACCCCCGCAGAGGAGGCCAAGAGCCCCGGGGAGCAGATCCAGATGACCTGGACTGAGAAGTGTGACGGTGAGCCGGCCAAACCGCCTAGTGCAGCCACACCAGAGGGCATCAAAGACATCTTCAACATGAAGCCCGAGTGGGAGAACCTGAACCAGTCCAATGTGCGGCGTATGCACACAGCGCTCCGGCTGAATGAAGTCATCATCAAAAAGTCCTCAGAGGCCAAGCTAGTCCTCCTCAACATGCCCGGGCCACCCAAAAACAGGACAGGTGACGAAAACTACATGGAGTTCCTCGAGGTCCTCACTGACGGTCTCAACCGGGTCCTCCTGGTCCGCGGAGGCGGCCGCGAGGTTATCACCATCTACTCCTGAAAGAGCAGCCCCCTCCCATGCCCCTCCCTCAGCCCCGTCCCTGTGTCAACCTTACTCCCACACTCTCATCAACGCTGCTTCATCATTATGTTTTCTCTCACCGCTTATTTCTGTAAGATAGTCCTCTCACACCCAACCAACAGCCCAGCTCAGCTTCAGCACCTCTCCCTCCGCTCCATCCCCAGCAGACCGATGAGCACTATCACACGCTCAGCAACTATAACTACTGTCAGCTCTAGACTCATTTAGACGCTATCTAGATTTGTTCTTGAAGAGACTTCTTTTCCTCGCTAGTCTTCGATGTACTGTAATAACTGGCATTGAGTCGGAGTCACTCTGcaaggaggaggtggtggtgttGGGTGTGGGTTGTTAAGCCGAGGTGTGAGCGCGCATGCATGTTTGTGTCCGTCTTTGTTTAAACCTTTGCATTCCTTATTGTTgggttatttaaattttttatttttttttcaaatataagtGTGGCataacagcagcagcttctGCTTGAATAGGAGAACGAGAGCCTAACTGAAATGAGCTCAACGTAGGATTGTCTGTTTAGTTCCGTTGTGGTGATCGCACACCTCCCACAGCGCTCCAGCCTGTTGTCTTCTATGTGATTTATCTTTCAAGGCAAAAAGACACTGCTACCCACTGTCAGGACCACCAGCTGGAAGGAGAACAGAGTCCTTAAGTATGAACTGTGAAATTCACATTGGTTTTCGAAGAAGACTGAAAAGGCATGTGGATCAAACCTTCAGTATTATCTTTAACCTGATTACTCCTTAGCATGGCGTCCTTATAACTGTGTGGGTGTTTCTACTCCACTTGTTGTGTTACCGCCATCACTGTCTTTCTACCTGTCCTCCTTTCAATTGATTTCTTAGTGGCTGTTCATCTCCTTGGCCACTGTtagtgccaaaaaaaaaaaaatacaacaaggCTAGCTTAGTTTGTAGAGATTGACACGTAATTAAAACTGTGAATAGTGCGTTTCCTACCAGAAGGCTGGTGTAACAATGGGGAGACAGTACAAACACCCCGAGGAGATTGTCATTGCCAGCACCCCTCGACTCTCGTGTGGATCACTGTAAATAATGTACAAGCTCTGACGCGTTGTTCAGTATGAGTGTAGTATTTTTGTGACATACTAAAAAGCTTCTAGTGGAGAGAAAACATTCCTTCGCTGAGAGGGACAGCTCAAAAACGCTGTTTTCAAcgtttatttatctatttatttattggatGGCATAGGCTCCTGTCACTATGGTAACCGTCATTGTAACCTCGACAAGCACTGCACCTGCACTGTCCGCCACTGTGCAACAAAGTGAAACTTTGATGAATTCATCAAATTcattaaataatacaaaaaaacactaaatgttattttttcatCTAGAgaacaaatatgtatttatgtttatagACAAAACTTACACATATTGATGAAATAGTTGTATGTCATTTTGATTGTCACTCAAAgatatattgttgtttttgccTAATTTAGATTACATTAAATGTGCCATATCAAAGTATTTTTCAAAGAGAAATAGTGAACAAAAATTCTATTGAATTAGAGGGAACAAAGTGTgctaaataaaagaaagaaaactgaGGTGTCTACATGAAACTAGTACGGTAATGATGACACCGTAGTTGGAAAGTCGCCCTATAGATGATAAAAGAATAGATGTTCGGACGCTCAGATTAAAAGCCGGTATATCAGCTGTTACAGAAGTGAGACTTTGAACATCTATCGATTGATTATTTAAAGGGTCAAGTCTAAATAAATGGAGAGGACAATGGCTTCTGTAGCTAGGAAACTCACATTGTCCACAAGACTGAACTCTATGCAGTAGACTCTCCAGTGAGATTTTATATCCTCTAGATTGGTTAAGATTTGAGCCTGACTGAATGACTGGTAAGCAAATCATATTTAGGTTCAAAAAGTGCATCTTGGAAGGAATGTGCAATAGTTGAAATCTGGACTCATGCGAtcatcttatttatttttttacacatatattttgtatatgtaGATTTCgtaagtctttaaaaaaaaaatccagaatcaTCTCACTTTGACCAAGGACAGCTGTCACtttaatttatttctgtttgtttttttctggaaGAAACTGTTTTTGGTCATTTGCACTTGTAGTagaaatatgaatataaataaataagtatatatatacagtatatacaatatAGGGAAGCAAAACAAATTAGTTTCTAGAACTATTTACAAACAGTATTTAATGTTTTTAGTGTTGCTTGAATGTCGGACCATATGTTGTGAATGCTGCTAGTATCAATAGATTTATTTCTACTGTAAATAGAGATGACTAAGCAACATTAAAGATGAAGGGATAAAGGGTATAGACATACATatcagtggtggtggtggtggttgttgTTTAACAAGACGAGGCTGTACCTGTAAACATTTGGCCTGAGGTCTCTGGACAGCATTagctttctgtttttattacaAAACTATACTGAATACCTTGATGCAATATTAAACAACTGAGGGCAAATCCCCCACCCGTTtattctctttaaaaaaaaaaaaaagctctcgATTATTACCATGTTTAATCCCATAAATAAAGTGAACCAATTTTAACGTACCAGATTATTAATTTACGTACTTTACTTCAAGAAATTTACAGGAATCacgaaaatgtttaaatatgaatatttatcTGCTAAACGTTACTGTTTGGAAATTTTTAACACACCTACCTTTGACACCTGTGATACTTAAGAAGCAGCCACTCCTAGTTTTTGAAGATTTTAGGGTGCCAAGTCATGAAGATTTTCTTTAATATGCTTGTCACGCTTAACTCTGACAAAGGGGTTGTTTAACGCTCACATTAGTTTTTGAAGAACATGGCTATTTTGGGATTGTCGCCACAACATTGCCTGCATCAACtgagccttttaaaatgtattcaaaagaAAAGATATCAGATGTTTATTGGAGAAGTTTATTGGAAatgaatttatttattgaattataaatgttttataattGCTGTTTGCATGGTACTATGTGGCAATATTTGTTTTAGTGGTTTCTATAGTGATGACTTACATGTTCAAGGTGCAGAGTGGGGTGAAAGGTTGTCAAATGTTGTCACCTCCTATCAACTATGGAGTGTTTGCCGCTCAGCCGGCGACATGGCTAAAAACCTTGAAAACAAGTCTTTTgcaaaaaataagaaaagtatGAGTTCACTATATTGTTACTTGTTATATTTCAATCTTGCTCAAATAGTCTTATGTAACGCAATAGGAGATTTTGAGTTTGCGAATGGATGAGCTGTAGAAATGGTCATTTCACCTTTGTAAATATGGATCACTTAAGTCAGAGACACTATAACCTACTAGTGTTGTCTTTTGTTGTACACTGTTCTATCACTGTGGACAAAGTCTTAGAGTTTTGTAAGATTATGTGCAATATTGTTCTCACATTGGtaagtttttacattttgtcacagttatgttatttattttctagACACAACTGGAGGTGTCACTTTATTTCATGAGAATGTTTGTCACCAGGTGTTACAGACAATAAAGGTCTACAGTGTTCATCCCAAATGTGGCTGAGACAGCAAAGCACTTTACACTGAAGGGGTACTCTGTGACAGGATCAGTctgcaggagtgtgtgtgtgtgtgtgtgtgtgggggggtctAACAAGAGCCAGCCTGCTCTGTACAGACTCTATCCCACAGTGATCTCTGGTGGCACACAAGTGTATTACAGCCAGCCGTGGAGGTCTGACAGCTCGGACTACAAAATAGAATTAATTCCCATCATGTTTAAGCAGTTTTCCGAACTGCAATAATCCAGAGACCTACCTGCTGATTTTGTTTACATCTTATCTTTTCAGCATTCTCTTGGACATTTTAGCATGCATCACATTCTTTCCTTTCTCTTGCCaaacttcttttaaaaaaaaaaaaaagaataatagtAACTGTTAAATTTATAGTGCTTGTCACTCAATCTGTGAGGTGAGCCTTCCCAGAATCCCTCCTCCACACCCCCAAACCCCTCTCCTCACCCCATCTGCCCCCAAATCCCTGGCCTCCCCCATCCCAGCCACTAAATCCACCCCAGCTCtgtattttaaatgtgattGCAGTATAATTCTGAAAAATGATCAAAGAATATAAAACTCGCGCTTCCAATTCTGGCACCGGCTCTGCTTGGACGACACAAGATAGTCGACTTAGAAACCAGCACGCCCCCTCTCCCCACAACTGATCCATGATTTAGATCAGATCCTTCGCCTGCACAACTGTAGCATGAGACAAACTTGCCGGTGATCATTACTCAGTCTCCATCCTTAAATGGATATTAAGGGCTCTGAAACACATCTGTTACCGGGTTGAGGAGGCTGTCCTGTTAAGACACCAACAgagaaaatatcaaacaagtcCCAGATTACGACAGAGAGGGCACACACAGTCTGTAGCTCAGATAAGATCGTAACCTTTAGTATATTTTCACAGAAGCAGCAGACAGATGTGCCTGATGTTGGAGGCAAAGCTGCACTTACATTACACACAGTCGACCTCTCTGGGAGCTAAAGAGAAGAACTCAAGTGGCTATCCACGCAGTGCAAGCAGAGCCAGGTCCCAGTCATGTTGTGTAACTCAGTGCATGCATGCAATTACCCTGAACAAGGTGTATTGAAAATATATTGGGTGTTTGTGGtataaaagtattttgtttatatcagttgggatattttctttcaagtagtatgtttttttttcttcttctctttccttaGGACTGGCCAATCATTGTATCCAAGATGAATATTATTATAGTACAAGATTCTATTTTTATGGTAGATTTATTGACAGGGTCTTCTTATTGTGTCAAATATTATCTGGAGATAAACTGATTACCAAAGTATATTTCAGTTAACTACATAAATGATGGTGTGCAAATGTGTGCTCCCGTGAATTAGACGCAGACAAGTAAATACTGTTTACTATTTTACAACATTTTGTAACAATTATCAttaatagatttaaaaaaaaaagtttgtgtcAATAGGGTAAAACTATGAAGTGCCAAAATAGGAGGAGAAGCCTGCAAATCCAGAATTTGGTGGAAGTCGCATGCCTGTCCAAAACTGTTCATTTACCCACTTTTCAGTAAATAACTGGGGTTAGGCTATATCCAGTCAATTATATTCAGTGAATGTATTAACTACAAAGGTTACCAATCACCAAAACTGGTCAGTCATGTCAACATTCAgacctttaaagaaaaaactTCTCAGCAcatagactggaaacagggaaacTGTCCAACGGTTACAAAATCCACCTAGCAGCATCTCTAAAGCTCATTTATTAACTCCTTGGATCGGGTTTGTTTAATCCATTCAAAACCAAAGTATAAAAAAGATTATACAAATttataaatacacatacatttcaTTAGAATTGTACCTTgtatgatttcatgtgacaaatatcGATTGATTTTATCTTCAGGTTACTGGTCCCGACCGGAAATAGTACGGTCCATAACCTCATAAAACCGTTTTTACGTCGTTTTTTGTACGGTTTAAACGTGTTAGTTATTGAGCTTTGGATTGTGTtatctttggacagagccattATCCAGTCTGTGTGCTTCATATTTAACTGACAGACCTGAGTGGTATCGATTTTCTCATTTTACTTTTGGGAACAAGCAATTTCCCGGAATTAATTTTCCTTTAATACTTTATGGCCTTTGAcaaatacagtattttatttaaaaaccaTACCTCCCTATAGAGGAATCTCGTCACTGTCCaggtttgtttttaattcacTGGAGTTGTGGGAAACATTTTGTATGGATGTTTGACAAATGTAACGGATGTAGGTATAGATGATATATacagcaaacacacaaagacacacctgTTTTGAATTTTGGTAATATGAAAGGGTTTTTCATTCAGAACCGTTCATTACTATACCTTGATACTGTACCTGGTCTTATGGTAAAGCCGTAGCGTGTTCCTTTCAGTTCTGtgggagtgtgtatgtgtgtacatgtaacTGCTGGGGGCGAGCTGGGAGGGGGCTACatgtaaataaatcaaatacagTTAG

Function

GO:

id name namespace
GO:1902476 chloride transmembrane transport biological_process
GO:0006812 cation transport biological_process
GO:0016021 integral component of membrane cellular_component
GO:0015379 potassium molecular_function

KEGG:

id description
K23967 SLC12A5, KCC2; solute carrier family 12 (potassium/chloride transporter), member 5

JBrowse2

Neighbor

RNA id RNA type direction distance location representative gene id
TU55840 lncRNA upstream 94980 25099287 ~ 25113176 (+) False LOC120558031
TU55836 lncRNA upstream 103203 25099287 ~ 25104953 (+) False LOC120558031
TU55837 lncRNA upstream 103203 25099287 ~ 25104953 (+) True LOC120558031
XR_005639044.1 lncRNA upstream 104836 25099301 ~ 25103320 (+) False LOC120558031
XR_005639045.1 lncRNA upstream 104836 25099301 ~ 25103320 (+) False LOC120558031
TU55900 lncRNA downstream 3192 25313719 ~ 25314259 (+) True G41570
XR_005639060.1 lncRNA downstream 188556 25499083 ~ 25500971 (+) True LOC120558141
TU55968 lncRNA downstream 235390 25545917 ~ 25546300 (+) True G41629
TU55969 lncRNA downstream 235982 25546509 ~ 25546840 (+) True G41630
TU55973 lncRNA downstream 371940 25682467 ~ 25685984 (+) False slc16a1a
XM_039798859.1 mRNA upstream 87790 25114918 ~ 25120366 (+) True LOC120558032
XM_039798617.1 mRNA upstream 261413 24923839 ~ 24946743 (+) True LOC120557917
XM_039796536.1 mRNA upstream 286780 24909084 ~ 24921376 (+) True rab22a
XM_039796533.1 mRNA upstream 316742 24888607 ~ 24891414 (+) True LOC120556805
XM_039796531.1 mRNA upstream 322127 24866174 ~ 24886029 (+) True cers5
XM_039796415.1 mRNA downstream 12867 25323394 ~ 25329667 (+) True capza1a
XM_039797941.1 mRNA downstream 20621 25331148 ~ 25345776 (+) True mov10a
XM_039799057.1 mRNA downstream 94953 25405480 ~ 25523601 (+) True tafa3a
XM_039796292.1 mRNA downstream 371880 25682407 ~ 25690935 (+) True slc16a1a
XM_039799208.1 mRNA downstream 382804 25693331 ~ 25702368 (+) False sycp1
TU55524 other upstream 1447205 23748910 ~ 23760951 (+) False cbfa2t2
TU55525 other upstream 1447205 23757758 ~ 23760951 (+) False cbfa2t2
XR_005638988.1 other upstream 3216357 21950376 ~ 21991799 (+) False itga7
TU54259 other upstream 5059466 20148104 ~ 20148690 (+) True G40353
XR_005638939.1 other upstream 5284607 19917889 ~ 19923549 (+) False abhd14b
TU56251 other downstream 958075 26268602 ~ 26273315 (+) True G41825
TU56292 other downstream 1231980 26542507 ~ 26548799 (+) False G41850
TU56293 other downstream 1231980 26542507 ~ 26548799 (+) False G41850
XR_005639013.1 other downstream 1342733 26653260 ~ 26698571 (+) False anks1ab
TU57106 other downstream 3929886 29240413 ~ 29242253 (+) True G42449

Expression Profile