RNA id: TCONS_00012264



Basic Information


Item Value
RNA id TCONS_00012264
length 801
RNA type mRNA
GC content 0.51
exon number 3
gene id XLOC_006260
representative False

Chromosome Information


Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 48358467 ~ 48381055 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence


CTCTCAGCTCCGCTACAACTGTAGGGCAGTTCTGAGTCTGCTGGGACAGAAGAAATGAATTAATTTGGAATAACTAAACAACACGTTTCAAGACGACATGGCAAAGCAAAGTTCCCTCTTTAACTTCTTCTCAAAGTCGCCTCCTCTCGCGGTGAAGGCCAAATCCAGCCCATCACCAGCAGAAGGAGATGCGCCGGGCAGATCCAACACTTCACCCAAGGAAGAAGCTAAAGTCAACAGCAAGAAAACACCTGCAAAACCGCCCTCAAAAACCCAAGCTATAGCCGGACACGCAAAGCTATTCGGGGAGAAAGCGGCCACTACAAAGGAAAGgaaacagtCACCTGTATTTAGTGCTGGCTCACTGGTATGGGCCAAGATGGAGGGGCATCCCTGGTGGCCCTGTATGGTTGTTCCTCAGCCTCTCAGCGGACAACAGATGAGGGGTCGAGGCCGAGACCAAAGGCTTCATGTTCACTTTTTTGATGAACCACCAACCCGAGGATGGGTGAACACAAAATACATAAGAGAGTACCAAGATGTGCTGCTGAGCATGTGCCGGTACAGTCAGAGCGCTGACGGGTCCATGGCCAGACCAGAGATGGCTCTTCCAGGCGACGGCTCTTATTCGGCCCCATTCCTGGATCTGAGGGGGTCTCGTCACCCTTGTGTCACCAAGACCTTCTTCGGGGATGACTTTATCCCTAATGACATCTTCATCGGCTGTCCTGGTGATGAAGAAGAGGCTCAAGATGATACCAAAGCACTTGCACCATGTGTACTAGTCACCGGACCAAACAT

Function


GO:

id name namespace
GO:0006298 mismatch repair biological_process
GO:0036297 interstrand cross-link repair biological_process
GO:0043570 maintenance of DNA repeat elements biological_process
GO:0016446 somatic hypermutation of immunoglobulin genes biological_process
GO:0016447 somatic recombination of immunoglobulin gene segments biological_process
GO:0006974 cellular response to DNA damage stimulus biological_process
GO:0045910 negative regulation of DNA recombination biological_process
GO:0000710 meiotic mismatch repair biological_process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage biological_process
GO:0006281 DNA repair biological_process
GO:0006290 pyrimidine dimer repair biological_process
GO:0032300 mismatch repair complex cellular_component
GO:0032301 MutSalpha complex cellular_component
GO:0030983 mismatched DNA binding molecular_function
GO:0032357 oxidized purine DNA binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0000400 four-way junction DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0032405 MutLalpha complex binding molecular_function
GO:0032137 guanine/thymine mispair binding molecular_function
GO:0003690 double-stranded DNA binding molecular_function
GO:0032143 single thymine insertion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008094 DNA-dependent ATPase activity molecular_function

KEGG:

id description
ko03430 Mismatch repair
ko05200 Pathways in cancer
ko05210 Colorectal cancer
ko01524 Platinum drug resistance
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-020905-3 Enables guanine/thymine mispair binding activity. Acts upstream of or within maintenance of DNA repeat elements. Predicted to be part of MutSalpha complex. Is expressed in several structures, including central nervous system; immature eye; neural tube; optic primordium; and ventral mesoderm. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal carcinoma; endometrial cancer; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Orthologous to human MSH6 (mutS homolog 6).

Ensembl:

ensembl_id ENSDART00000162531

JBrowse2


Neighbor


RNA id RNA type direction distance location representative gene id
TCONS_00013684 lncRNA upstream 294229 48063125 ~ 48064309 (+) False XLOC_006259
TCONS_00013685 lncRNA upstream 294229 48063128 ~ 48064309 (+) True XLOC_006259
TCONS_00013681 lncRNA upstream 904630 47189134 ~ 47453908 (+) True XLOC_006249
TCONS_00013686 lncRNA downstream 182123 48552706 ~ 48556760 (+) False XLOC_006262
TCONS_00013688 lncRNA downstream 182370 48552953 ~ 48556760 (+) False XLOC_006262
TCONS_00013687 lncRNA downstream 182370 48552953 ~ 48556760 (+) True XLOC_006262
TCONS_00013689 lncRNA downstream 198404 48568987 ~ 48587143 (+) False XLOC_006263
TCONS_00013425 lncRNA downstream 208351 48578934 ~ 48587410 (+) True XLOC_006263
TCONS_00012260 mRNA upstream 519173 47821524 ~ 47839365 (+) True XLOC_006256
TCONS_00012259 mRNA upstream 542490 47810211 ~ 47816048 (+) True XLOC_006255
TCONS_00012258 mRNA upstream 630927 47710434 ~ 47727611 (+) True XLOC_006254
TCONS_00012256 mRNA upstream 666828 47623916 ~ 47691710 (+) False XLOC_006253
TCONS_00012267 mRNA downstream 111673 48482256 ~ 48551810 (+) True XLOC_006261
TCONS_00012268 mRNA downstream 247391 48617974 ~ 48652585 (+) True XLOC_006265
TCONS_00012272 mRNA downstream 805041 49175624 ~ 49206649 (+) False XLOC_006271
TCONS_00012273 mRNA downstream 805364 49175947 ~ 49206713 (+) True XLOC_006271
TCONS_00012275 mRNA downstream 1356750 49727333 ~ 49769372 (+) False XLOC_006274
TCONS_00012262 other upstream 312310 48046112 ~ 48046228 (+) True XLOC_006258
TCONS_00012261 other upstream 454356 47904068 ~ 47904182 (+) True XLOC_006257
TCONS_00012254 other upstream 1222684 47120482 ~ 47135854 (+) True XLOC_006247
TCONS_00012252 other upstream 1308512 47049912 ~ 47050026 (+) True XLOC_006248
TCONS_00012251 other upstream 1315575 47039477 ~ 47042963 (+) False XLOC_006247
TCONS_00012270 other downstream 532362 48902945 ~ 48903059 (+) True XLOC_006269
TCONS_00012271 other downstream 612103 48982686 ~ 48982800 (+) True XLOC_006270
TCONS_00012280 other downstream 2150085 50520668 ~ 50521600 (+) True XLOC_006285
TCONS_00012281 other downstream 2232056 50602639 ~ 50602714 (+) True XLOC_006286
TCONS_00012283 other downstream 2423173 50793756 ~ 50793872 (+) True XLOC_006288

Expression Profile


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