XLOC_010253 (ica1)


Basic Information

Item Value
gene id XLOC_010253
gene name ica1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 47207691 ~ 47232146 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020267
ATGGAGAAAGGCAACCAAGGTTTTGATCAATTTCTCCAAAGTCAAGAATCCTCCGTGGTAAACAAGTTCCAGCAGAAATACTGGAAAACCAAACAAACGCTTATCAAAGTCACTGGAAAGAAGGAGGATGAACATGTTGTTGCCTCGGATGCAGATCTTGATGCTAAACTTGAGGTGTTTCATTCAGTACAGAGAACATGCATGGAGCTTCTCAAGGTGATCGAACAGTATCAAAGGAGGATCAGCCTTTTGTCCCAGGAGGAGAATGAACTGGGTCGGTTCCTGCGTTCACAAGGCTCTCAGGACAAAAGTCGTGCTGGAAAGATCATGCAAGCTACTGGAAAAGCACTCTGCTTCTCTTCCCAACAAAGGTTGGCACTGCGAGGGCCGCTGGGTCGCCTGTACCAGGAGGTGGAGACTTTTCGTTACCGAGCTATTTCAGACACATGGCTGACAGTGAACCGGATGGAGCAGTCGCGCACAGAGTACAGAGGAGCACTGCTCTGGATGAAGGACGTTTCTCAGGAGCTCGACCCGGACACACACAAGCAGATGGAGAAGTTTCGGAAGGTTCAAACTCAGGTTCGTCATACCAAGACAAGTTTTGACAAACTGAAGAACGACGTGTGTCAGAAGGTTGATCTGCTGGGAGCCAGTCGCTGTAATCTGCTCTCACACGTCCTGACAACCTATCAGACCACACTGCTGCATTTCTGGGAGAAAACCTCTCACACGATGGCTGCTATTCACGAGAGTTTCAAAGGCTGTCAGACGCACGAGACTTCAGCGGGTTCAGATCAAGCggtaaagaaaaaaatgaagaagaaaagcaaagcaaaaacagACGACGAGACGAGTCCCGCTACAGATGAAACGCTTATTTCTCTTGAGCAGGAAACTCAGAGCAGCAACACCACGCACACAGGTAACACCGAACAGAGAAGAAATGAcactaacttattagatcaaatattatatgcaggaacactggaagatgcttccacaacaacaccgtggcgccgcttcaagggTTTCGAAGATTacgacttatcaaaaaaatccaaatgcccaacacaaAAAACGCAAAgcgaaaaaaatttttttttgagaaataaaattatgaatacTAATATGTTCAGTATCATGGTCTGCTTTTCAGGTTCTTTATCAGCCATTCTTCAGAATAATCCTGGAAGCTCATCTGTAGCCGGTCAAAACTCTTCCAAACCTGCAGTGAACGaatcCTCCAAAGATCTGTCAGCGTGGTTCAGTCTGTTTGCTGATCTGGATCCACTGGCCAATCCGGATGCTATCGGCCGTAGCGGAGCTGATCACGACCTGCTGACTgcttga

Function

symbol description
ica1 Predicted to enable protein domain specific binding activity. Predicted to act upstream of or within regulation of insulin secretion. Predicted to be located in Golgi membrane and secretory granule membrane. Is expressed in central nervous system; neurons; rhombomere; and ventricular zone. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1).

GO:

id name namespace
GO:0050796 regulation of insulin secretion biological_process
GO:0030667 secretory granule membrane cellular_component
GO:0000139 Golgi membrane cellular_component
GO:0019904 protein domain specific binding molecular_function

KEGG:

id description
ko04940 Type I diabetes mellitus

ZFIN:

id description
ZDB-GENE-040718-490 Predicted to enable protein domain specific binding activity. Predicted to act upstream of or within regulation of insulin secretion. Predicted to be located in Golgi membrane and secretory granule membrane. Is expressed in central nervous system; neurons; rhombomere; and ventricular zone. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1).

Ensembl:

ensembl_id ENSDARG00000042608

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020267 True 1353 mRNA 0.46 19 47207691 47232146

Neighbor

gene id symbol gene type direction distance location
XLOC_010252 NXPH1 coding upstream 3390 47203422 ~ 47204301 (+)
XLOC_010250 thsd7ab coding upstream 29557 46869010 ~ 47178134 (+)
XLOC_010251 CR848802.1 coding upstream 195234 47012341 ~ 47012457 (+)
XLOC_010249 NA coding upstream 377454 46826588 ~ 46830237 (+)
XLOC_010248 CABZ01027551.1 coding upstream 399677 46807214 ~ 46808014 (+)
XLOC_010254 col28a1b coding downstream 76710 47308856 ~ 47344147 (+)
XLOC_010255 NA coding downstream 151649 47383795 ~ 47389378 (+)
XLOC_010256 slc25a32b coding downstream 196575 47428721 ~ 47450004 (+)
XLOC_010257 NA coding downstream 532079 47764225 ~ 47764819 (+)
XLOC_010258 NA coding downstream 766686 47998832 ~ 47999411 (+)
XLOC_010247 NA non-coding upstream 410365 46796426 ~ 46797326 (+)
XLOC_010246 NA non-coding upstream 413519 46790677 ~ 46794172 (+)
XLOC_010241 NA non-coding upstream 638207 46556343 ~ 46569484 (+)
XLOC_010259 CR388140.1 non-coding downstream 791147 48023293 ~ 48023408 (+)
XLOC_010260 CU929195.1 non-coding downstream 926163 48158309 ~ 48158423 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_00798826_00806532 ICA1 coding CI01000027 null 798686 ~ 806532 (-)