XLOC_012197 (gdf7)


Basic Information

Item Value
gene id XLOC_012197
gene name gdf7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 30835076 ~ 30839338 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00024021
ATCGGCGCTGTATCCCTCTGATAACGGGCTCCACTCACATCTGGATGCGCGCGGTCCAGCAGGAACCAGCGCGAGCTCCCGGAACGAGTCCACATCTGTTCATGTTCCGTCTTACATGATCTCTCTGTACAGAACTCTGTCTGAACTGGACCGACGGACTGGTAACGGCAGTCACACGCGCTCCAGGAGATATGCCAACACGGTCACCAGCTTCATGGATCTGGGGCAAgATGAGCCTTCACTTATGTTCCAGCAGCAGTACACATTCAACCTGTCTGGACTCTCCCGACTGGATGAACTGATGGAAGTGGAGCTGCGGGTTCTGAGGAGGCCACCGCAAGATGTCTTAAGCTTACTCTCTTATGGTGGGAACCTGTATCGTCTGCTGCTTCACACCTGCTCACTTCCAGGATCTCTTCACCAACCTTTGCTTCTCAGCTCCAGGACCATCGATCTTCTAGATACCTCTTCAGCCACATGGGATGTGTTTGATGTCGGCCCAATCATAAAGACCCCCCTCAAGCAGCACAGGACTGCAGAAGACACTAGGTTGTTGTGCCTTAGCATATCTGCTGTTTCTGATTCAAATAACGAGGCTGTGCATCCTGGGATGCTGGGTCTAAGCCGCGAGGATCAGCAGACCCATGAAAGAGCCTTACTAGTGGCGTTTTCTCAAGCACGGAGGAAGGAGAACCTCTTTAGGGAGATCCGTGAGAAGATAAGGGCTATGAAAAGTCGGAAGTTTTCTAATCCCACACCAGAGCATAGTATCAAAGGTCATCCGAGGCATCGGCGGAGGAGAAGGACAGCACTAGCAGGCCGTCCCGGAGTAGGACCCATTACCAGCGGAGGAAAGGGAGGTGGAAGACGGAGGACACGCTGCAGCCGGAAACCGCTTCACGTGAATTTCAAAGAACTTGGTTGGGATGACTGGATTATTGCACCGCTGGATTATGAAGCATATCACTGTGAGGGTTTGTGTGACTTCCCTTTGCGCTCACACCTGGAACCAACCAACCATGCCATTATTCAGACCCTCATGAACTCCATGGACCCAGAGTCCACCCCTCCCAGTTGTTGTGTACCCTCAAAACTCAGTCCCATCAGCATTCTGTACATTGACTCGGGGAATAATGTGGTTTATAAACAGTACGAGGACATGGTGGTGGAGAGTTGTGGGTGCAGGTAG

Function

symbol description
gdf7 Predicted to enable cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; liver; muscle; and pleuroperitoneal region. Orthologous to human GDF7 (growth differentiation factor 7).

GO:

id name namespace
GO:0060395 SMAD protein signal transduction biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
ko04350 TGF-beta signaling pathway
ko04390 Hippo signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04360 Axon guidance
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-990714-1 Predicted to enable cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; liver; muscle; and pleuroperitoneal region. Orthologous to human GDF7 (growth differentiation factor 7).

Ensembl:

ensembl_id ENSDARG00000042784

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00024021 True 1189 mRNA 0.52 2 30835076 30839338

Neighbor

gene id symbol gene type direction distance location
XLOC_012196 zgc:194392 coding downstream 132665 30700627 ~ 30702411 (-)
XLOC_012195 alkal2b coding downstream 169039 30661348 ~ 30666037 (-)
XLOC_012194 sh3yl1 coding downstream 182338 30604819 ~ 30652738 (-)
XLOC_012193 NA coding downstream 242018 30573572 ~ 30593058 (-)
XLOC_012192 itsn2b coding downstream 314033 30473507 ~ 30521043 (-)
XLOC_012198 yy1a coding upstream 17670 30857008 ~ 30863252 (-)
XLOC_012199 evla coding upstream 57954 30897292 ~ 30975978 (-)
XLOC_012200 eml1 coding upstream 137146 30976484 ~ 31082381 (-)
XLOC_012201 BX571712.1 coding upstream 256988 31096326 ~ 31097541 (-)
XLOC_012202 pkdccb coding upstream 311877 31151215 ~ 31164219 (-)
XLOC_012190 NA non-coding downstream 425317 30398949 ~ 30409759 (-)
XLOC_012189 NA non-coding downstream 465551 30306215 ~ 30369525 (-)
XLOC_012188 NA non-coding downstream 554363 30278131 ~ 30280713 (-)
XLOC_012186 NA non-coding downstream 752363 30077331 ~ 30082713 (-)
XLOC_012203 BX571712.2 non-coding upstream 342612 31181950 ~ 31185243 (-)
XLOC_012208 BX539317.1 non-coding upstream 545096 31384434 ~ 31384548 (-)
XLOC_012218 NA non-coding upstream 1288559 32127897 ~ 32136128 (-)
XLOC_012219 CR407546.1 non-coding upstream 1406791 32246129 ~ 32246255 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000189_03097932_03102218 GDF7 coding CI01000189 null 3097682 ~ 3102815 (-)