XLOC_013295 (mlycd)


Basic Information

Item Value
gene id XLOC_013295
gene name mlycd
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 14233553 ~ 14274803 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026299
GCAACATAATACAAGACGGTTTATTTTGGTGCGTGTTTGACAGGCGCGCAATGACACCTTTCCACTTAAGTACAGTCGCGCGATCTTTGCTAAAGTCGTATCGACACAGAGCTGTACTAAAAACAATCCACGGACTCCGACTCTGGGATTTTCAAAGCATGCATCCACGCTCCTCCATCGCAGGGCACGAACTCATGGAGGAGATCCTGAGGAAGACTGTGGCCCCATTGCCCAGCTACGAGATGAGAGACAAATCTCCACCTCCACCCGAATCCAACAGTTTGGAGTTCATGCATTTTTACAAGAGTTTAGAGAAAGAGCAGAGGCTGGAGTTCCTCGAGAAGTTGTCTCATGATTTCGGGGTTGATCACAGGTGGGCTTCGGATCTGGCCGCAAAGTTGCTGGAGGCTCAGGTGCGGGATGTGGCCACCATCCTGCAGGTGGAGGACAGGCTACGGTACAGTTTGACACCCCGGTACCGACAGCTGCTCACCCACATCAGCAGGGTGCAGGGCGGGGTGAAGTTTCTGGTGGACCTCAGGGCAGATCTCATCGAGTTCGCATCCTCAAAAATTAGTGACAGCCCACATATGAGGgacctgaacagcactctGAAGGCTCTTCTGTCTGAATGGTTCTCTGTTGGGCTCCTCCGACTTGAAAGAATCACTTGGCAGTCCCCATGCGAAATCCTTCAGAAGATCAGCCAgtaCGAAGCGGTGCACCCTGTGAGAAACTGGACAGATCTGAAGCGCAGAGTAGGGCCAAACCGGAGGTGTTACGCCTTTACCCACGCATCCATGCCCGGAGAACCACTGGTGGTGCTGCATGTTGCTTTAACTGAGGACATAGCAAATAATATCCAGGGCATTGTGAGAGAGTTTGCCACTCTTGATGCAGATGAGGATGTGAATAAAATCAACGCCGCCATCTTCTACTCCATCTCTTCCACCCAGGCCGGACTGCAGGGGGTGGAGCTGGGCAATTACCTGATCAAGAGGGTGGTCCGAGAACTACAGAGCGAGTTTCCACACATGGCCCAGTTCTCCAGTCTGTCTCCGATCCCTGGCTTCTCCTTATGGCTCCAAGGGGCTTTGGGACAGCACAAGAAGGAGGGTCGAGCCACAGAGCTCCTCTCTGAGCAGGAGTGGCGGGAAGTGGAGGACGTGACGGGAGCTGCTCCTGGTGCCCCGGCTCTGGAGGCCCTGCGCAGACTCATCAGCACCAGCGAGTGGATTCACTCTGACCGTCTGGTTCGTGCTTTGGAGCCTGCGCTCATGCGGCTCTGTGCTTGGTATCTGTTTGGTGAAAAACGACGAGGGTACGCTCTCAACCCCGTAGCCAACTTTCACCTTCAGAACGGCGCCACCATGTGGAGGCTAAACTGGCAAGCCGATACAAGCCCAAGAGGAATCGCCAACTCCTGTGGAATAATGGTCAATTATCGCTACTTTTTGCAAGAGACTGGCACTAACAGCATCGCTTACCTGCACAATAAAGTCATCAAGGCCTCGGAGCAGGTGCTGGGACTGGTGTCACAATTTCAGAGGAACAGCAAACTCTGAGATGAATATGAAGTTCTGTGTTGGGACAGTAATGCATTGGCACTTAATTTCAGTGTTATCGTTTTTTGATAACTGAGTGATTTGAATTTAAAGGACAAACACACAATGAGGGTGGAATATGCCTTAAATATCCAATGGGACACATGGTACAATGGGATGTACGATTGAAGCATatcatatttgatttttattCAGAGATGGACAGTTGATAATCTGCCTTTCTGAAAGACAATCATCCAATAAATCCAATTAtaatggatagttcattcaaaaa

Function

symbol description
mlycd Predicted to enable malonyl-CoA decarboxylase activity. Predicted to be involved in acetyl-CoA biosynthetic process; malonyl-CoA catabolic process; and positive regulation of fatty acid oxidation. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase).

GO:

id name namespace
GO:0006633 fatty acid biosynthetic process biological_process
GO:0006085 acetyl-CoA biosynthetic process biological_process
GO:0046321 positive regulation of fatty acid oxidation biological_process
GO:2001294 malonyl-CoA catabolic process biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0005782 peroxisomal matrix cellular_component
GO:0050080 malonyl-CoA decarboxylase activity molecular_function

KEGG:

id description
ko00640 Propanoate metabolism
ko00410 beta-Alanine metabolism
ko04152 AMPK signaling pathway
ko04146 Peroxisome

ZFIN:

id description
ZDB-GENE-070410-120 Predicted to enable malonyl-CoA decarboxylase activity. Predicted to be involved in acetyl-CoA biosynthetic process; malonyl-CoA catabolic process; and positive regulation of fatty acid oxidation. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase).

Ensembl:

ensembl_id ENSDARG00000104732

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026299 True 1839 mRNA 0.50 5 14233553 14274803

Neighbor

gene id symbol gene type direction distance location
XLOC_013294 BX950204.1 coding downstream 689186 13544250 ~ 13544367 (-)
XLOC_013293 BX890576.1 coding downstream 755331 13477102 ~ 13478222 (-)
XLOC_013292 cmip coding downstream 870627 13324140 ~ 13362926 (-)
XLOC_013291 BX511124.1 coding downstream 945902 13281654 ~ 13287651 (-)
XLOC_013290 klhl36 coding downstream 1030152 13195745 ~ 13203401 (-)
XLOC_013296 hsbp1b coding upstream 59320 14334123 ~ 14337458 (-)
XLOC_013297 si:dkey-238o13.4 coding upstream 396986 14671789 ~ 14677936 (-)
XLOC_013298 pdf coding upstream 413840 14688643 ~ 14691727 (-)
XLOC_013299 tshz3a coding upstream 456981 14731784 ~ 14743659 (-)
XLOC_013300 NA coding upstream 489100 14763903 ~ 14765883 (-)
XLOC_013384 BX323829.1 misc upstream 5267299 19542102 ~ 19542231 (-)
XLOC_013288 NA non-coding downstream 1119235 13077843 ~ 13114318 (-)
XLOC_013286 CT573465.1 non-coding downstream 1287822 12945617 ~ 12945731 (-)
XLOC_013308 BX649610.1 non-coding upstream 761348 15036151 ~ 15036269 (-)
XLOC_013310 NA non-coding upstream 913214 15188017 ~ 15191812 (-)
XLOC_013319 BX928740.1 non-coding upstream 1313284 15588087 ~ 15588201 (-)
XLOC_013321 CR854977.1 non-coding upstream 1600859 15875662 ~ 15875780 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_07375912_07390782 MLYCD coding CI01000013 null 7373818 ~ 7391003 (+)