CI01000339_05924933_05931878 (HMBS, HMBSA)


Basic Information

Item Value
gene id CI01000339_05924933_05931878
gene name HMBS, HMBSA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000339
NCBI id null
chromosome length 8057057
location 5924715 ~ 5932584 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000339_05924933_05931878.mRNA
CTACATAAACATCCCACAAGGCTCATTTCCCCTCCCAAAAAAAGGATTCATTTGTCAGACGACTCTTACTTTAAACTGGTTTATAAATATGATTTTCAAATAATTATAAAGATGTCAAAATTTTATTTATTTATTTATTTTTTTTTAAATTACTCAACATTTTGAGACATCATCTTCGTTTGGTTGAATTATGCGCTGTGTGGCGCTGCATGACGAGCATGAACACATCTACAGCGTGTTCTTGGCAGACGGAAGTATCTTTCCCGTCTAGGTCACACCTCAGAAATCAGGAAGGAAATGGCAAAGTCAGTCGGGTTATTCGCATGGGAACAAGGAAGAGCCAGCTGGCTCGCATTCAAACAGACAGTGTGGCCAGCACACTGAAAGCGCTTTATCCAGATGTTCATCTAGAGATAGTTGCCATGTCGACAATTGGGGACAAAATCCTGGACACTGCGTTATCAAAGATTGGCGAAAAGAGCCTCTTCACCAAAGAGCTGGAAAATGCCCTTGAGAGAAATGAAGTGGATATTGTGGTTCACTCTCTTAAGGATTTACCTACCTCATTGCCCCCTGGATTCACTATTGGAGCCATTCTTCAGCGGGAAAATCCCCATGATGCAGTGGTGCTTCATCCAAAGAATGCTGGACTTACCCTGGACAGCCTGCCAGAGAAGAGTGTGATTGGCACAAGTTCACTTCGCAGAGCAGCTCAGCTGAAGAAACGATTTCCTCAACTGGAATTTGAAAATATTAGAGGGAACCTAAACACCCGCCTAAAGAAGCTGGATGAAAAGGACGACTATGCTGCCATCATTCTGGCCGCAGCAGGCCTCAAACGTATGGGCTGGGAAAACCGAATCAGTCAAATTCTCGGCCCGGAAGATTGCATGTATGCAGTTGGCCAGGGAGCACTGGCAGTGGAAGTCAGAGCACAAGATAAAGATATTCTGGAAATGGTGTCTGTCCTGCACCATCCAGACACAGTGCTGCGGTGCATCTCAGAGAGAGCTTTCCTCAAACAGTTGGAAGGAGGCTGCAGTGTGCCTGTTGCTGTTCATACAGAAGTGAAAGAGTCCATGTTGTATTTGACTGGAGCAGTTTATAGTTTGGATGGAGCTGATTGCTTGAAGGACACTATGCAGACGTGTGTGGAAATAGACAACAAAGTGAGTGAGAGCGCACAGGAGTGCGTACACGTTGCAGTCACTGCCAACAATATATCATCATCAGCCCTCGATGCTGCTGAGAAACTGGGGATGGATCTGGCAAATGTTCTCCTTAACAAGGGGGCCAAAGATATTCTCACAACAGCCAGGAAACTTAATGATGCTCGATAACTTTTTTTTTTCTTCACATTTTGTGCACTGGAGTTAGTTGAGACCTATTTTAGGAATCTTTGACATGCTGTTAACTTGATAAACAGTACCCTCAACTGTATGATCTATAGCACAACCATGACTGGGTGAATTATCAAGTCACTTCAGCTACTATACCTCAGTTTAACAATGTGACAACACCAATTTTTCTGTCAGCTGTTCGTTCACTCACAAGTCACAAATTTCGACTGCCATCATCTCTCAGGCACAGAATTCTGGAAGAAAATTCATGTTTATAGTCTTCCTCTTCTAATGATCAGGCTGCCTTTATCTGTGAACCACATAAAATGAGGTGCTCAAAATGGCTACCTTTTACATCTGGCCATGGTTTTTAATATAGAAATGAGTAGCCTCTAGCAAAATGTTTATGTGTATATCTTTAATTTTAAAAATATATTTTATCACTGTGGAATACTATAAAACTAATCAGTATTGAGAAGCTAAGATGTGATTTCGGGATCTATGTAAGATTTTTATTGGCAAAATATTCAGTTTAAAAAGTTTGCTTAAGTTAAAAGATTAATTAGAATATGTATATATTTTGTCAAAGAAAACGCCATAATGTGCCTTATAAACGTTGAATTGTAAAATGAATTAACCATAGCAAATCACTTTGACCAGCAATGTTAATGTTTTCTGTAACTATCAAAATGAGAAAAACACGTGA

Function

symbol description
hmbsa Predicted to enable hydroxymethylbilane synthase activity. Predicted to be involved in heme biosynthetic process. Predicted to act upstream of or within peptidyl-pyrromethane cofactor linkage and porphyrin-containing compound biosynthetic process. Predicted to be active in cytoplasm. Is expressed in intermediate mesoderm. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Orthologous to human HMBS (hydroxymethylbilane synthase).
hmbs Enables hydroxymethylbilane synthase activity. Involved in heme biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Implicated in acute intermittent porphyria and sickle cell anemia. Biomarker of prostate carcinoma; seminoma; and urinary bladder cancer.

NR:

description
Porphobilinogen deaminase

GO:

id name namespace
GO:0033014 tetrapyrrole biosynthetic process biological_process

KEGG:

id description
K01749 hemC, HMBS; hydroxymethylbilane synthase

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000339_05924933_05931878.mRNA True 2046 mRNA 0.41 14 5924715 5932584

Neighbor

gene id symbol gene type direction distance location
CI01000339_05841485_05849982 STK36 coding upstream 74182 5841485 ~ 5850533 (+)
CI01000339_05836831_05840321 NA coding upstream 83982 5836831 ~ 5840733 (+)
CI01000339_05655376_05675186 ADAMTS15A coding upstream 249132 5655179 ~ 5675583 (+)
CI01000339_05599544_05600935 TIMM8B.S, TIMM8B coding upstream 323499 5599544 ~ 5602261 (+)
CI01000339_05544723_05561118 NA coding upstream 362746 5544318 ~ 5561969 (+)
CI01000339_05968915_05972679 DPAGT1 coding downstream 35746 5968330 ~ 5973090 (+)
CI01000339_05974223_05980520 HINFP coding downstream 41639 5974223 ~ 5980566 (+)
CI01000339_05982674_05984181 NA coding downstream 50090 5982674 ~ 5984201 (+)
CI01000339_05994065_06027592 ABCG4, ABCG4A, ABCG4B coding downstream 61481 5994065 ~ 6028547 (+)
CI01000339_06033619_06038517 PDZD3B coding downstream 101035 6033619 ~ 6038540 (+)
G483822 NA non-coding upstream 3992 5918828 ~ 5920723 (+)
G483862 NA non-coding upstream 88492 5835833 ~ 5836223 (+)
G483860 NA non-coding upstream 96801 5827690 ~ 5827914 (+)
G483859 NA non-coding upstream 97037 5827369 ~ 5827678 (+)
G483856 NA non-coding upstream 99253 5825234 ~ 5825462 (+)
G483894 NA non-coding downstream 113835 6046419 ~ 6046876 (+)
G483907 NA non-coding downstream 269806 6202390 ~ 6207166 (+)
G483980 NA non-coding downstream 361116 6293700 ~ 6293903 (+)
G483981 NA non-coding downstream 361632 6294216 ~ 6294517 (+)
G483989 NA non-coding downstream 373519 6306103 ~ 6358859 (+)
G483672 NA other upstream 684931 5227323 ~ 5239784 (+)
CI01000339_03088452_03091633 NA other upstream 2835010 3088110 ~ 3091633 (+)
CI01000339_02821530_02821886 MRPL41 other upstream 3100822 2820576 ~ 2823479 (+)
CI01000339_02196706_02198050 GABARAPL1, GABARAP.L, GABARAP, GABARAPA, GABARAPB, BRAFLDRAFT_122660, GBRAP other upstream 3725906 2196307 ~ 2198809 (+)
CI01000339_06041909_06043927 ATP5L other downstream 109233 6041817 ~ 6044034 (+)
G484139 NA other downstream 1013802 6946386 ~ 6966146 (+)
G484134 NA other downstream 1014209 6946793 ~ 6947480 (+)
G484172 NA other downstream 1181999 7114583 ~ 7115459 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_030168 hmbsa coding NC_007116.7 CM002889.2 30518036 ~ 30534426 (+)