XLOC_014335 (tpmt.1)


Basic Information

Item Value
gene id XLOC_014335
gene name tpmt.1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 47290287 ~ 47298657 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028458
ACAAATTCTTCCTGTTATGAAAGCGAAGTCAGTCGGCGGACAGTGAACTTTACAACCATTGGGAGATGTCAGCGCAGGCCGACCGGGTGATGGATCTGTCCGAGTGGGAGAACCGCTGGCAGGAAGGAAGAACCGGTTTCCACAGATCTGATGTGCACAATTTGCTGAAAGCTAATGTGGACAAACTCATATGTGGACGACGGGAGGTTCGGTTCTTCTTCCCGCTTTGTGGAAAGGCTGTAGATATGAAATGGCTGGCTGATTTGGGGCACACGGTTGTTGGAGTTGAATTTTCGGAAAAAGGAATTAAAGAGTTTTTTCAAGAGCAAAATCTGGAGTATAATGAAGAAGCTGTGGCAGATATTCCTGGAGCAAAGCTTTTCAAGAGCACAGATGGGAAGATCTCCATCTATCAGTGTGATTTATACAAGTTCTCCAGTGCTGTTGCGGGACACTTTGGAGGGATCTGGGATCGAGGAGCACTGGTGGCTATAAACCCATGTGATCGGCAAAAGTATGCGAGTCTGCTTGTGTCTTTAATGAGCAGCGACTGCAGATATCTGCTGGACACGCTGGAATATAACCCTGAGCTTTATAAAGGTCCACCATTCTTTGTGTCAGAAGACGACATAAAAACTGTATTCGGAGGAAGCTGTAATATTGATCTTCTGCAGAGTGTGGATGGTTTCGAGGAGAAGCACAGATCATGGGGACTGGATTCACTCACAGAGAAACTTTACCTGCTCACTACTAAAACTTAGTAATCATCACCAGACCAGACCAGCGTTACAAACTCATCACTTGACAACAGCAACAAATGCATAAGGGACTCACAAATAAGGATGCAGAAAAGATGCAATTATTTTCCAattttaataacagatttttgctattttaatattTGGACATTATTGTacaataattgaataaattgttatattttgaga

Function

symbol description
tpmt.1 Predicted to enable thiopurine S-methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase).

GO:

id name namespace
GO:0032259 methylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0008119 thiopurine S-methyltransferase activity molecular_function
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0008168 methyltransferase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050522-141 Predicted to enable thiopurine S-methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase).

Ensembl:

ensembl_id ENSDARG00000055974

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028458 True 947 mRNA 0.43 9 47290287 47298657

Neighbor

gene id symbol gene type direction distance location
XLOC_014334 NA coding upstream 98786 47188530 ~ 47191501 (+)
XLOC_014333 si:ch211-229b6.1 coding upstream 152862 47135677 ~ 47137425 (+)
XLOC_014332 AL953858.1 coding upstream 464604 46824723 ~ 46825683 (+)
XLOC_014331 NA coding upstream 852152 46423091 ~ 46438135 (+)
XLOC_014330 med30 coding upstream 878929 46372115 ~ 46411358 (+)
XLOC_014336 tpmt.2 coding downstream 509 47299166 ~ 47309383 (+)
XLOC_014337 CU138512.1 coding downstream 7966 47306623 ~ 47306738 (+)
XLOC_014338 ext1c coding downstream 12363 47311020 ~ 47336408 (+)
XLOC_014339 NA coding downstream 38925 47337582 ~ 47338157 (+)
XLOC_014340 psmb2 coding downstream 95613 47394270 ~ 47423628 (+)
XLOC_014325 NA non-coding upstream 1071247 46216335 ~ 46219040 (+)
XLOC_014321 NA non-coding upstream 1196635 46091317 ~ 46093652 (+)
XLOC_014317 NA non-coding upstream 1562225 45727214 ~ 45728062 (+)
XLOC_014341 NA non-coding downstream 139547 47438204 ~ 47448594 (+)
XLOC_014344 CU695215.2 non-coding downstream 275958 47574615 ~ 47574823 (+)
XLOC_014345 NA non-coding downstream 291372 47590029 ~ 47591236 (+)

Expression


Co-expression Network