XLOC_016273 (kdm4ab)


Basic Information

Item Value
gene id XLOC_016273
gene name kdm4ab
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 17450228 ~ 17492486 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032084
ATGCGCAGAGCTTGAGTGCTGATGGAGGTTTGTCAGAAGAAGCATCTGCTGTTAGCCAAACATCTATACGAAGGTTAAGGGAAGTTATTAGGGTTTTGTTTGACAAAGTCAGTGTTAAGGACTCGGTCAGCCAAGATGGCATCTGACATGCCAGTTTCCAGGGGTATAATGACCTTTCACCCCACCGTTGAAGAGTTCAAGAACTTCAGCCGCTACATTGCGTACATGGAGTCACAAGGTGCACACAAAGCAGGCCTAGCCAAGATCGTCCCACCGAAAAACTGGAAGCCTCGAGGTTCTTATGATGACATTGATGACCTGATCATACCTGCACCGATTCAGCAGGTTGTGACTGGGCAGTCGGGGCTGTTCACTCAGTACAACATCCAGAAAAAAGCCATGACTGTGAAAGAGTTCCGCAAAACCGCCAACAGCGACAAGTTTTGCAGTCCTCGATATGATGATTTTGAAGAACTCGAaaggaaatattggaaaaatgtaaccTTTAATCCTCCCATCTATGGAGCTGATGTGAATGGGACACTTTATGACCCGGATATCAAAGAATGGAACGTAGGGCACTTGAATACTATCCTAGACACAGTGGAGCATGAAAGTGGAATCACTATCGAGGGAGTGAACACACCCTACCTCTACTTTGGCATGTGGAAAACCACTTTTGCCTGGCACACAGAGGACATGGATCTCTACAGCATCAATTACTTACACTTCGGGGAACCAAAGTCTTGGTACACCGTGCCTCCTGAACATGGAAAAAGACTGGAGCGGTTAGCTAAAGGCTTTTTCCCTGGAAGTTCACAAAACTGTGAAGCCTTTCTCAGACACAAGATGACTCTTATTTCACCTTCCATTTTAAAGAAGTATGGCattccttttgaaaagATCACTCAGGAAGCTGGAGAATTTATGGTGACGTTTCCGTATGGCTATCATGCAGGCTTTAACCATGGTTTCAACTGTGCTGAGTCTACAAATTTTGCCACGAGGCGATGGATTGACTATGGAAAACAAGCCATACTGtgTTCTTGCAGGAAAGACATGGTGAAAATCTCCATGGATGTGTTTGTGAAGAAATTTCAGCCTGAACGGTACGAGCTGTGGTTGGAGGGGAAGGACAACGCACCCATTGATCACTCTAAACCCACGCCTGAAGCAGCTGAGTTTTTAGGTGGAGAGGCTGGTGCTCAAGAACTCCGCATTGAGAACCAAAGTAATGAGGGACAAAAAAAGAGCCTGGCCAAACAAAGGATAGGAACCAAAAGACACAGGGTGTGTCTGGACTTTCCAGAGGAAGTTCTTCCAAAGACTGAAACAAATGATGAGGCTGAATATGGCAAGAAGGGCCGATTGACTCCATACACAGAACAGTGCAAGGAGTATACAGAGTTGAAGCATGAAGACCGCACACTTCCACTGATGGGTTCAACCAGTTTAAAGATGCTGCCAGGATCCAGAAGTGCTGAATTTTCGGAAAACGTTCGGGGTGCTGGTTTTAGTGACGCAGACCTGGATGCTAAAGCAACTAGCCATATTTCAGCCTGTGCGCAGCCCTTCCCAAAGCATCACCTCTCTATCGCATCTGTCCCTACTGTCCCACACTGCTTGTCAGCTGTGCCACGGGTATCCACCAAACCAGGGGTGGCAAGCCTTCTCTTTCATCGCACCCTCAGCCCGACAGATGCCCTGCAGGTCCACAGCTACGCAGCCAAAGCTGCACTCTGTAAACCACAAACACCCAGTCCAGAGAAACCCAGAGAAGACCTACACATACCAGACATCAGTCTAGACGTGAGGCCAAATACACCAACTCCACCCCCAGACACACCAGAGCACGAAATTGAAGGTGAGAAGGAGAATAACAGCATGAAGAGGAAACTGCAGCCGCTCAGCAAGTTGCCGCGTTTGCATCCTCTGCTCCGAGAGAACTCCAGTGATGACGAGATCCAGGAGCCAACAGCTGAGCCAGAGGAGACCGATCCCTGGGCTAAAATCCTGGCTCCCATGTGGCAGAGCAGACAACGCAACTTTCAGATCGAGAAGGAGTTCAACTTCCGCATGGGCCTGCATCCACCGTACTGTGCAGTGTGTTCCCTCTTTCACACCTACAATGAGAGTGATGTAATCAGCCTGGGCGGTTTTGCAGCTgtaggaggaaacccacaaaggACCAAACCTCTGATTCCAGAGATGTGCTTCACCAGCAGCTCTGAAGGACATCTGTCCACTCCTAACCTGGAGGCGGACGGCACTAGCCAACTCATCAGCTGCTCTGTGTGCAGTGTGCGCGTACATACAAGTTGTTATGGTGTGTCTCAGGATGCTAAGTTAGACAGCTGGAGATGTTCCCGCTGTGAAGCTAACGCCATTACTCAgGACTGCTGTTTATGCTCTCTGAGAGGAGGAGCACTGCAGAGAGCCAACAATGACAAGTGGGTTCATGTGTTGTGTGCTGTAGCAGTGCTGGAGGCTCGCTTCGTCAACATTGCAGAGCGCAGACCGGTTGATCTCAGCACTATCCCGTTTCAGAGATTTAAACTGaaatgtcAATTCTGCCGAAAGTGGGTTAAGAAGACCACAGGCTGCTGTGTGCAATGTTCGCACGGCCGCTGCTCCACTTCCTTTCACGCCACATGTGCACAGGCAGCTGGAGTTCAGATGCATCCTGATGATTGGCCGTTTGTTGTCTACTTCACTTGCTGGAGGCACAAGGGCGGCACCCACATAGAGCGCAATATGGCATCCATGCGGGAGTTGGAGAAAGGACAAAAAGTGATCTGCAAGCACAAAAATGGCCGGTACTATCACTGTGAAGTGGTTGAGCTGACTAAGGCCACCTTTTATGAGGTTATATTTGATGATGGCTCATTTAGTGACAACCTCTTCCCTGAGGATATAGTGaatagaGACTGTACGCGGCATGGTCCACCATCAGAGGGCGAAGTGGTTCAAGTACAATGGACAGATGGCCTCATCTATGGAGCCAAATTTGTATCTGACCACATCATCCCCATGTACCAGGTTGAATTTGAAGATGACTCTCAGCTTACTGTGAAGAGGGAAGATGTGTTCAGTTTGGACGAGGAGCTGCCCAAACGTGTTAAATCCCGACtgtctgTGGCATCAGACATGCGCTTCAAAGGAGTGTTTGTGGAGAAGGAAGTGAAGCAGGACTCAAAAAGACAGCGAGTGATCAACTCCCGTTACAGAGAAGACTACATTGAACCGGCCATCTACAGAGCAATCTTGGAGTAACTCAATCCACAAACaatatctttaaaacaaaaaccaaTTCACCAATAACACGGCAAACAGAGAAACAGGCTGGAGCAGACACATCGTCACATGATCGGACAACGGCAAATACAATTCTACCGCTGcgccttttgtttttaaaaccatcAAGATCAACTTTTTAGGCCGAGTATGAATTCGGACAGCACAGATGAGAGTCTCAGAGATGAAATGCTAGGAATGTCTTGTGTAAGAGTGTTTGTTTGTTCGCACAGCACACAAGCGGTTCGGGATCAGCGGGTGGCGGTGGACGGCTCTCGGACTCCTACTATCTTTAGTCAGGTGGCAGTAATGTTTTTTAATCACCTCCCTGCAGACCCACCGGCTGACCGAGCATCAACAAACCTTTAGATGGTCCGACCGATCTGCGGTCAGCATGGATGATGCGTCACCCCGCTGACCTTTTTTATCGGTCTGAAAGTGCTTGGCAATATCAAAACCTCATGGATGTACCTAGTCTTTATTAGTACGAGCAGCTCTCATGTGTGATCTACTGTAAACATGAGACGTCGTAGAGAGATAGCTTTATACTCTCACGGTTAGGTGCATACAGCagctttagttttatttaatttattcttttgttgAAGTGTGAGGAACGGCCGTTTCCTTGTTGAGCATCAGTTCTGTTTGTAAACCGATCTATTTATATGTTGAAGGCAGGTTTTTTCCTACTTTTTCTACTCTTAGTTGGTTAAACTGGTGCACTTATCCacatgtttgtttctgttttcctTCAGTTGTGAGTTTTTTAATCATGGTACTTAAGGCAGGGAAGGCAACATCTCTAAGTGCCCTGTTAAGAGGGCGCCTAAAGAAGTGCCTCGttcaaatcattatttaaaataatgtgttttttttttttttttgtggagattgctttagttgttTAGCATTACAGACCCTTCAGTTGTCTTGTGTGATAGGCATTACACTCCTTTGTCTTGGATTATAGATCCATTGTTAATTTAAggctacaaaaaaaaactttatttttaaattaaaagcaatGTCTCCTTTTCCCTGA
>TCONS_00032085
aagTCCAATGCCACAAACATGAAATAGTTAAATAATGCTCTTAACTCTGCGCGAAGTTAAACAGTTCAGTCTCTCTGCAGCCACAAACACATATTacgactctttttttttttaaatgtaatgacaTGTTTAGGAATAATAATGGCGGTATACTGCTACAAACGGACTTTAAATTACATCAACATGTCAAACTCCTCAGTGCAAATAAGCAAACAACATTAAACTAGCCCATAATGAAAGTTATCTACAAACGGATGCTCAGTAGTACATGATAAACGTTATCTCTGGCCAAGTCTCTCTCTGGCTGATTTTGCAGGCAGGCTACTGTAAACGTGACCGTGATCTGATTGGTTATGGAGATACTGGCGTGGGTGGACCAATAATAGTAAACAAATCCTGTGAGCGCATGCGCAGAGCTTGAGTGCTGATGGAGGTTTGTCAGAAGAAGCATCTGCTGTTAGCCAAACATCTATACGAAGGTTAAGGGAAGTTATTAGGGTTTTGTTTGACAAAGTCAGTGTTAAGGACTCGGTCAGCCAAGATGGCATCTGACATGCCAGTTTCCAGGGGTATAATGACCTTTCACCCCACCGTTGAAGAGTTCAAGAACTTCAGCCGCTACATTGCGTACATGGAGTCACAAGGTGCACACAAAGCAGGCCTAGCCAAGATCGTCCCACCGAAAAACTGGAAGCCTCGAGGTTCTTATGATGACATTGATGACCTGATCATACCTGCACCGATTCAGCAGGTTGTGACTGGGCAGTCGGGGCTGTTCACTCAGTACAACATCCAGAAAAAAGCCATGACTGTGAAAGAGTTCCGCAAAACCGCCAACAGCGACAAGTTTTGCAGTCCTCGATATGATGATTTTGAAGAACTCGAaaggaaatattggaaaaatgtaaccTTTAATCCTCCCATCTATGGAGCTGATGTGAATGGGACACTTTATGACCCGGATATCAAAGAATGGAACGTAGGGCACTTGAATACTATCCTAGACACAGTGGAGCATGAAAGTGGAATCACTATCGAGGGAGTGAACACACCCTACCTCTACTTTGGCATGTGGAAAACCACTTTTGCCTGGCACACAGAGGACATGGATCTCTACAGCATCAATTACTTACACTTCGGGGAACCAAAGTCTTGGTACACCGTGCCTCCTGAACATGGAAAAAGACTGGAGCGGTTAGCTAAAGGCTTTTTCCCTGGAAGTTCACAAAACTGTGAAGCCTTTCTCAGACACAAGATGACTCTTATTTCACCTTCCATTTTAAAGAAGTATGGCattccttttgaaaagATCACTCAGGAAGCTGGAGAATTTATGGTGACGTTTCCGTATGGCTATCATGCAGGCTTTAACCATGGTTTCAACTGTGCTGAGTCTACAAATTTTGCCACGAGGCGATGGATTGACTATGGAAAACAAGCCATACTGtgTTCTTGCAGGAAAGACATGGTGAAAATCTCCATGGATGTGTTTGTGAAGAAATTTCAGCCTGAACGGTACGAGCTGTGGTTGGAGGGGAAGGACAACGCACCCATTGATCACTCTAAACCCACGCCTGAAGCAGCTGAGTTTTTAGGTGGAGAGGCTGGTGCTCAAGAACTCCGCATTGAGAACCAAAGTAATGAGGGACAAAAAAAGAGCCTGGCCAAACAAAGGATAGGAACCAAAAGACACAGGGTGTGTCTGGACTTTCCAGAGGAAGTTCTTCCAAAGACTGAAACAAATGATGAGGCTGAATATGGCAAGAAGGGCCGATTGACTCCATACACAGAACAGTGCAAGGAGTATACAGAGTTGAAGCATGAAGACCGCACACTTCCACTGATGGGTTCAACCAGTTTAAAGATGCTGCCAGGATCCAGAAGTGCTGAATTTTCGGAAAACGTTCGGGGTGCTGGTTTTAGTGACGCAGACCTGGATGCTAAAGCAACTAGCCATATTTCAGCCTGTGCGCAGCCCTTCCCAAAGCATCACCTCTCTATCGCATCTGTCCCTACTGTCCCACACTGCTTGTCAGCTGTGCCACGGGTATCCACCAAACCAGGGGTGGCAAGCCTTCTCTTTCATCGCACCCTCAGCCCGACAGATGCCCTGCAGGTCCACAGCTACGCAGCCAAAGCTGCACTCTGTAAACCACAAACACCCAGTCCAGAGAAACCCAGAGAAGACCTACACATACCAGACATCAGTCTAGACGTGAGGCCAAATACACCAACTCCACCCCCAGACACACCAGAGCACGAAATTGAAGGTGAGAAGGAGAATAACAGCATGAAGAGGAAACTGCAGCCGCTCAGCAAGTTGCCGCGTTTGCATCCTCTGCTCCGAGAGAACTCCAGTGATGACGAGATCCAGGAGCCAACAGCTGAGCCAGAGGAGACCGATCCCTGGGCTAAAATCCTGGCTCCCATGTGGCAGAGCAGACAACGCAACTTTCAGATCGAGAAGGAGTTCAACTTCCGCATGGGCCTGCATCCACCGTACTGTGCAGTGTGTTCCCTCTTTCACACCTACAATGAGAGTGATGTAATCAGCCTGGGCGGTTTTGCAGCTgtaggaggaaacccacaaaggACCAAACCTCTGATTCCAGAGATGTGCTTCACCAGCAGCTCTGAAGGACATCTGTCCACTCCTAACCTGGAGGCGGACGGCACTAGCCAACTCATCAGCTGCTCTGTGTGCAGTGTGCGCGTACATACAAGTTGTTATGGTGTGTCTCAGGATGCTAAGTTAGACAGCTGGAGATGTTCCCGCTGTGAAGCTAACGCCATTACTCAgGACTGCTGTTTATGCTCTCTGAGAGGAGGAGCACTGCAGAGAGCCAACAATGACAAGTGGGTTCATGTGTTGTGTGCTGTAGCAGTGCTGGAGGCTCGCTTCGTCAACATTGCAGAGCGCAGACCGGTTGATCTCAGCACTATCCCGTTTCAGAGATTTAAACTGCGCAATATGGCATCCATGCGGGAGTTGGAGAAAGGACAAAAAGTGATCTGCAAGCACAAAAATGGCCGGTACTATCACTGTGAAGTGGTTGAGCTGACTAAGGCCACCTTTTATGAGGTTATATTTGATGATGGCTCATTTAGTGACAACCTCTTCCCTGAGGATATAGTGaatagaGACTGTACGCGGCATGGTCCACCATCAGAGGGCGAAGTGGTTCAAGTACAATGGACAGATGGCCTCATCTATGGAGCCAAATTTGTATCTGACCACATCATCCCCATGTACCAGGTTGAATTTGAAGATGACTCTCAGCTTACTGTGAAGAGGGAAGATGTGTTCAGTTTGGACGAGGAGCTGCCCAAACGTGTTAAATCCCGACtgtctgTGGCATCAGACATGCGCTTCAAAGGAGTGTTTGTGGAGAAGGAAGTGAAGCAGGACTCAAAAAGACAGCGAGTGATCAACTCCCGTTACAGAGAAGACTACATTGAACCGGCCATCTACAGAGCAATCTTGGAGTAA

Function

symbol description
kdm4ab Predicted to enable histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to several human genes including KDM4A (lysine demethylase 4A).

GO:

id name namespace
GO:0006338 chromatin remodeling biological_process
GO:0048514 blood vessel morphogenesis biological_process
GO:0035097 histone methyltransferase complex cellular_component
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0032452 histone demethylase activity molecular_function
GO:0032454 histone demethylase activity (H3-K9 specific) molecular_function
GO:0051864 histone demethylase activity (H3-K36 specific) molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-6279 Predicted to enable histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to several human genes including KDM4A (lysine demethylase 4A).

Ensembl:

ensembl_id ENSDARG00000019103

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032084 False 4339 mRNA 0.47 22 17450228 17492080
TCONS_00032085 True 3490 mRNA 0.47 21 17451294 17492486

Neighbor

gene id symbol gene type direction distance location
XLOC_016272 st3gal3b coding downstream 56257 17266759 ~ 17393971 (-)
XLOC_016271 artnb coding downstream 214337 17200320 ~ 17235891 (-)
XLOC_016270 pif1 coding downstream 334972 17096161 ~ 17115256 (-)
XLOC_016268 clcn2a coding downstream 405269 16885285 ~ 17044959 (-)
XLOC_016269 BX640595.1 coding downstream 505837 16944272 ~ 16944391 (-)
XLOC_016274 ptprfb coding upstream 85834 17578320 ~ 17947389 (-)
XLOC_016275 pbx1a coding upstream 1205902 18698388 ~ 18830794 (-)
XLOC_016276 NA coding upstream 1607936 19100422 ~ 19109304 (-)
XLOC_016277 kncn coding upstream 1627361 19119847 ~ 19128385 (-)
XLOC_016278 NA coding upstream 1659886 19152372 ~ 19181569 (-)
XLOC_016267 CU929319.1 non-coding downstream 834173 16615940 ~ 16616055 (-)
XLOC_016265 CR377211.2 non-coding downstream 930848 16512861 ~ 16519380 (-)
XLOC_016264 CR377211.4 non-coding downstream 937806 16508824 ~ 16512422 (-)
XLOC_016263 NA non-coding downstream 943433 16502780 ~ 16506795 (-)
XLOC_016280 BX511079.1 non-coding upstream 1759784 19252270 ~ 19269297 (-)
XLOC_016282 BX511079.2 non-coding upstream 1870312 19362798 ~ 19363161 (-)
XLOC_016283 NA non-coding upstream 1886625 19379111 ~ 19382322 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G13570 NA non-coding CI01000001 null 1664265 ~ 1664492 (+)
grasscarp (Ctenopharyngodon idella) CI01000004_03681226_03695729 KDM4AB, KDM4A coding CI01000004 null 3681108 ~ 3696553 (-)
tiger barb (Puntius tetrazona) G10170 kdm4ab,LOC107564389,LOC107700543,LOC107551714,LOC107684932,LOC107743373 unknown NC_056700.1 CM032069.1 7492206 ~ 7493844 (-)