CI01000004_03681226_03695729 (KDM4AB, KDM4A)


Basic Information

Item Value
gene id CI01000004_03681226_03695729
gene name KDM4AB, KDM4A
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000004
NCBI id null
chromosome length 17451736
location 3681108 ~ 3696553 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000004_03681226_03695729.mRNA
TTGAACAGAGTTATAATTTAGGGAGGTAAGAAGTCATACTATATTGCACTAGAAAACTGAAACTGTAAGTTTCAGAACTCAAAACTTCCTCCAAGAACATTTATTGTTTCCACTCTTACCCCCATCTTTTTTTTACTAGACTACACTAAACACTATAAATGTATAAAATAGTAAATCATCTTTGTCATTTTTATTTAGTCAGTAGGCCTAACACATTAGGCTATATTTGTTCTAATCATTACCTTTTTGTTTGCCAGCAAGTAGAACATGAATTCCTTTTAACTTCTATATTTTAAAGTTAAATCCCCTTTAATGACACACTTAGCTTGTGCATTGAACTAAATAGGCTATGTTAGAGGGAACTGGAAATTTAAGCTAGTAGACTACAACACTGTGTAAATGCCACTTAGTCTTCCTGTACGATAATTAAGCTAACTACTTTGATGGTACATCAGTTTTTCACTACATTTTCACATCTTGTCTTTTGCTCCAGTATCACCCCCAAAAAAGCATATAGTCGACGTGTGTGAAGGAATGTTACGAAGTTCAAGTAAAACCAGTACTGGAATGGATGGATTGTTTAGGTCTATTTTTAAGAGCGTTTGATCTGTTTGGTCTCTTTTTTAACGTTTATAGCAAGGATACTTTCAAGTCACCGACAGTTCCCGTTATCGGATTCTGTCATCTGCAGTTACAGTAGGCTAGAGTACAGTAGTCATTCAGATTCGTAGCTTTACTGGTATTATTTAGGCTATTTACTGGTATTATTGGTTGTATTATTTACTGCTCTGGTAAAAAAGAAGCTTTACATTACCATTATTAAAATGACATACAGATGCTACATGCAGGTGCTAAGGACTCGGTCGGTCAAGATGGCATCGGACACCCCGGTTTCTAGGGGTATTATGACCTTTTACCCCACTGTTGAAGAGTTCAAGAACTTCAGTCGCTACATTGCGTACATGGAGTCCCAAGGTGCACACAAGGCAGGCCTGGCCAAGATCATCCCGCCGAAAAATTGGAAGCCTCGACGTTCATACGATGACATTGATGACCTGCTAATACCTGCACCGATTCAGCAGGTTGTGACTGGGCAGTCAGGGCTGTTTACCCAGTACAACATCCAGAAAAAAGCCATGACTGTGAAAGAATTCCGCAAAACAGCCAACAGTGACAAGTTTTGCAGCCCTCGGTATGATGATTTTGAAGAGCTTGAAAGGAAATACTGGAAAAATGTAACCTTTAACCCTCCCATCTATGGAGCTGATGTGAATGGGACCCTTTATGACCCAGATGTCAAAGAATGGAATGTAGGGCATTTGAATACCATCCTTGACACCGTGGAGCATGAGAGTGGTATTACTATAGAGGGAGTAAACACACCCTACCTCTACTTTGGCATGTGGAAAACCACTTTTGCTTGGCACACTGAGGACATGGATCTGTACAGCATTAATTACTTACACTTCGGGGAACCAAAGTCATGCATTTATCGTGTTCTGAAATGCCTGTACATTACATGGTGCATCAATCTTGGCATATTATTTCTTCAGTGTTCATGTAGGAAAGACATGGTGAAGATCTCCATGGATGTGTTTGTAAGGAAATTTCAACCCGAACGGTATGAGCTGTGGTTGGCGGGGAAGGACAATGCTCCCATTGACCACTCCAAGCCTACGCCTGAAGCAGCTGAGTTTTTAGGTGGAGAGGCTGGAAAGAGCGGTGCTCAGGAACTCTGCATTGAGAACCAAAGTAGTGAGGGACAAAAGAAAAGCCTGGCCAAACAAAGGATAGGAACCAAAAGACACAGAGTGTGTCTGGACTTACCAGAGGAAGTTCTTCCAAAGAGTGAAATAAACGATGAGGAGGCTGAATATGGCAAGAAGGGGCGCTTGACTCTATACACAGAACAATACAGAGAGTATCAAGAATTGAAGGACGAAGATGACCTGCTGCCACTGATGGGTTCGACCAGTTTAAAGATGCTTCCAGGTTCTAGAAGTCCTGCATCTGGGGAGTGTGTTAGGGGTGCAGGTTTTAGTGCCACAAACCTGGTCTCTAAAGCTACTTCTCTGTCCTCAGCCTGTACACAGTCCTTCCCAAAGCGTCATCTCTCTATAGCATCTGTCCCTACTGTCCCTCACTGCCTGTCAGCCGTGCCACGGATTTCTACCAAACCAGGGGTGGCGAGCCTTCTCTTTCATCGGACCCTGAGCCCTTCAGATGCCCTTCAGGTCCATAGCTATGCAGCCAGATCAGCGCTCTGTAAACCTCAGCAACCCATGACACAGGAACCCAGAGAAGACCTCAAAGACCCAGACATTCAACAAGATGTGAGGCCAAATATGCAAACTCCACAACCAAACACAGAGCATGAAATTGAGGGAGAGAAAGAGAATAAAAGCATGAAGAGGAAACTGCAGCCACTCAGCAAGTTGCCACGTTTGCATCCCCTGCTCAGAGAAAACTCCAGCGATGACGAGATTCAGGAGCCAGCAACAGAGCAAGAGGAGACCGATCCCTGGGCCAGACTCCTTTCTCCCATGTGGCAAAGCAAACCTCGCGATTTTGAAGTTGAGAAGGATTTCAACTTCCGCATGGGCCAGCAACCTCCGTACTGTGCAGTGTGTACCCTCTTTCACACGTACACACAGAGTGATGTAATCAGTCTGATCCAGTGCGGTTCTGCAGCTGAAGGAGGGGACCAGCAGAAGACCATGCCGCTGATTCCCGAGATGTGCTTCACCAGCAGCTCTGAGGGACACCTGTCCACCCCAAATCTGGATGAAGATGGCACTAGCCAACTCATCAGCTGCTCTGTGTGTAGTGTGCGCGTTCATACCAGTTGTTATGGTGTGTCTCAGGATACTAATCTGGACGGGTGGATGTGTTCCCGCTGTGAAGCGAATGCCATTACTCAGGACTGCTGTTTATGCTCTCTGAGAGGAGGAGCTCTGCAGAAGGCCAACAATGACAAGTGGGTTCATGTGTTATGTGCCGTGGCAGTGCTGGAAGCTAGATTTGTGAACATTGCAGAGCGCAGTCCTGTTGATCTCGGTAATATCCCGCTTCAGAGATTTAAGCTGGCAGCCGGAGTTCAAATGCACCCAGACGACTGGCCATTCGTTGTATACTTCACCTGCTGGAGACACAAGGGCGGCACCCAAGTGGAGCCGCGCAACAAAGCATCAATGCGGGAGTTGGAGAAGGGACAGAAAGTGATCTGCAAGCACAAAAATGGCCGATACTACCATTGTGAGGTGGTTGAGCTGACCAAGGCCACCTTCTATGAAGTTATCTTCGATGATGGCTCATTCAGTGACAACCTCTTCCCTGAGGATATAGTGAATAGAGACTGTCAGCAGCTCGGTCCACCATCAGAGGGCGACGTAGTTCAAGTGCGCTGGACAGATGGCCTGATCTATGGAGCCAAATTTGTGTCTGACCATATCATCCCAATGTACCAGGTGGAATTTGAAGATGACTCTCAGCTCACTGTAAAGAGGGAAGATGTGTACAGTTTGGACGAGGAGCTGCCCAAACGTGTTAAAGCCCGACTGTCTGTGGCGTCGGACATGCGCTTCAAAGGGGTGTTTGTGGAGAAGGACGTGAAGCAGGACTCGAAAAGACAGCGGGTGATCAACTCCCGTTATAGGGAGGACTACATCGAACCGGTCATCTACAGAGCCATCATGGAGTAGCACTTCACAAACTCCTCACAAACAATATCTTCAACACACAGATCAATTGGCCGACGCCACTAACAACATAACAAACAGAAAAACAGGCTGGACCAGACACCTTAATGTTTTGAGTAAA

Function

symbol description
kdm4ab Predicted to enable histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to several human genes including KDM4A (lysine demethylase 4A).
kdm4a Enables several functions, including histone demethylase activity; ubiquitin protein ligase binding activity; and zinc ion binding activity. Involved in histone lysine demethylation; negative regulation of cellular metabolic process; and negative regulation of gene expression. Located in cytosol; fibrillar center; and nucleoplasm. Biomarker of several diseases, including alopecia areata; lung cancer; prostate cancer; stomach carcinoma; and urinary bladder cancer.

GO:

id name namespace
GO:0005634 nucleus cellular_component

KEGG:

id description
K06709 KDM4, JMJD2, JHDM3; [histone H3]-trimethyl-L-lysine9/36 demethylase

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000004_03681226_03695729.mRNA True 3819 mRNA 0.46 19 3681108 3696553

Neighbor

gene id symbol gene type direction distance location
CI01000004_03612407_03645686 ST3GAL3B coding downstream 33644 3611978 ~ 3647464 (-)
CI01000004_03594612_03595116 NA coding downstream 85967 3594133 ~ 3595141 (-)
CI01000004_03588875_03589130 NA coding downstream 91855 3587976 ~ 3589253 (-)
CI01000004_03559459_03560064 NA coding downstream 121044 3559459 ~ 3560064 (-)
CI01000004_03556991_03559357 ARTN coding downstream 121751 3556482 ~ 3559357 (-)
CI01000004_03705008_03734116 NA coding upstream 7590 3704143 ~ 3735494 (-)
CI01000004_03737431_03794978 PTPRFB, PTPRF coding upstream 40817 3737370 ~ 3795450 (-)
CI01000004_03802203_03806124 NA coding upstream 104583 3801136 ~ 3807171 (-)
CI01000004_04062573_04103207 NA coding upstream 364644 4061197 ~ 4103361 (-)
CI01000004_04177460_04183900 PBX1A, PBX1B, PBX1 coding upstream 480907 4177460 ~ 4183993 (-)
G26955 NA non-coding downstream 7953 3672939 ~ 3673155 (-)
G26948 NA non-coding downstream 23239 3657554 ~ 3657869 (-)
G26924 NA non-coding downstream 132413 3548474 ~ 3548695 (-)
G26854 NA non-coding downstream 274281 3406403 ~ 3406827 (-)
G26837 NA non-coding downstream 325636 3355215 ~ 3355472 (-)
G26902 NA non-coding upstream 122630 3819183 ~ 3929949 (-)
G26889 NA non-coding upstream 187812 3884365 ~ 3907456 (-)
G26983 NA non-coding upstream 260191 3956744 ~ 3956954 (-)
G26992 NA non-coding upstream 282053 3978606 ~ 3978816 (-)
G26995 NA non-coding upstream 291690 3988243 ~ 3988560 (-)
G26788 NA other downstream 405387 3267683 ~ 3275721 (-)
CI01000004_01773383_01774888 INSL5B other downstream 1906167 1772928 ~ 1774942 (-)
G27746 NA other upstream 1481674 5178227 ~ 5203724 (-)
CI01000004_05617072_05627369 NA other upstream 1923830 5616644 ~ 5628289 (-)
CI01000004_06539836_06541252 NA other upstream 2838274 6538904 ~ 6541252 (-)
G29388 NA other upstream 2934740 6631293 ~ 6631907 (-)
G29656 NA other upstream 4267811 7964364 ~ 7965500 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_016273 kdm4ab coding NC_007113.7 CM002886.2 17450228 ~ 17492486 (-)
grasscarp (Ctenopharyngodon idella) G13570 NA non-coding CI01000001 null 1664265 ~ 1664492 (+)
bowfin (Amia calva) AMCG00006180 NA coding CM030142.1 CM030142.1 19648606 ~ 19681766 (+)
tiger barb (Puntius tetrazona) G10170 kdm4ab,LOC107564389,LOC107700543,LOC107551714,LOC107684932,LOC107743373 unknown NC_056700.1 CM032069.1 7492206 ~ 7493844 (-)