XLOC_017752 (pak6b)


Basic Information

Item Value
gene id XLOC_017752
gene name pak6b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 53521648 ~ 53568849 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035111
GCGCCTGCAAAACACCCGAGCAGATCTTCAATGTGCTGTTTATGTCCTCCAGAATACCGAGGTTTAAGTGAACAAGGATCCACAACACTATACGAGTGACTCAGACGGATGGAGACGCTCCCTGCGCAGTGAACATGCAGCGGCACGCAGACAGCAGGAACACAGGCCGAGTGTGTGCGTTCATCTGTGCTTCAGTCCGCAGAGCGTGGCATTCCTGGACATGAGTTCTGCATCAACTTGAGCTTGATGAAGAGCGGAGACACAGAAGGCGCTGGATGAAGGAGTGTGTCTCACTCAGGTCCTTTACTGCTGCTCAGACTCTGCTGGAGGAAATGAACAGCTGAACTGAGGAAAACACTCGATCTTACAGGCCGCCAGAATGTTccagaggaggaagaagaagaagaggaagttgGAGATCTCCACACCTAAGAACTTCCAGCACCGCGTGCACACTTCTTTTGACCCAGTTCAGGGTTGTTTTATCGGGTTGCCGCCGCAATGGCAGAGCCTCATAGAGACGCTGAAGAGGCCCAAACCAGTGGTGGACCCGTCCAGCTTCACACAGGTGCAGGTCAGACCACAGAagAGCATCGTTCGTGGAAGTTTCATCGGACACGAGGACTACATTTCAGCGGCGATCGCTCAGATGAGCCGACTCTCCGTCACCAGCTCCAACTCTTTAAGAAGAAGGAGTCCGTCTGTGAGAAAAAGAGCGCAATCATTAGGTCGACTGGGGGAATTAGCAGAAGCAGAGACTTATGAATATGAGGAACTCAATAATACTAACCACAGGAATAGTTCAGATTTACACAGAGGATCCAGACCGATCCAGAGTCCGCAAACTGAGTCTAGACAATCACCAGCAAGAGCTCGATCCGTTCACGAGGCGACCATGTTTACAGGACTGATGCCCAGAGATATCTTACTGCACAGGGCTGGGTGTGAAGGAACCGATAATGCTGGGAATAAACCAAACCAGAGGCCGGTGTCGTGTTTGTACAGCCAAAGTGATGGAGCCAAACTGAACTCGGATCAGCTGAAGATGGAGACGCAGAGGAGGCCGCAGTCTACCTATGACTTTAAGGTCAATTCTCCAAATCTTCCAGCTGCATCTAAACCCAATGGCACCAGCAGTCCAAAACCAGGCCATGGGATAATCTCTATGCAGACGCCTCGCCGTTCCTCCACTGATAACACCCTCAAACTCTCCACTATCCCAGCCGATGTTCCTCCAGCACAGGACAGCCCGTCAGAGCCCAGACAGGCCCCAAGCGGAGCCTCGTCTCCTGGGCTGACAGAGCCcagcgtcacacacacacagttcagagCCGCGCTGCAGATGGTGGTGGATCCGGGAGACCCGCGCTCATACCTGGAGAACTTCATCAAGATCGGGGAGGGCTCGACTGGGGTGGTGTGCATCGCCAGAGAGAAGCACAGCGGACGACAGGTGGCCGTCAAGATGATGGACCTGCGCAAACAGCAGAGGAGAGAGCTGCTCTTCAATGAGgtGGTGATCATGCGGGACTACAGGCATCAGAATGTGGTGGAGATGTACAAGAGTGCGCTGGTTGGTGAAGAGCTGTGGGTGATCATGGAGTACCTGCAGGGCGGCGCTCTCACCAACATCGTCTCAGAGACCAGgctgaCAGAGGAGCAGATAGCAACGGTGTGTGAGTCTGTCCTGCAGGCTCTGTGTTATCTTCACTCTCAGGGAGTCATCCACAGAGACATCAAGAGCGACTCCATCCTGCTGACGTTGGACGGCAGGGTCAAGCTGTCAGACTTTGGCTTCTGTGCTCAGATCAGTAAAGACGTACCCAAGAGGAGGTCTCTGGTCGGGACTCCATACTGGATGGCACCGGAGGTGGTTTCTAAGACGCCGTACGGCACTGAGgtGGATATTTGGTCTCTGGGCATCATGGTGGTGGAGATGGTTGATGGAGAACCTCCGTATTTTAGCGAAACACCAATTTCTGCTATGAAGAGACTGAGAGACGAGCCGCCGCCGACCGCCAGAAACGCCAGCAAGATCTCTCCTGTCCTGCGGGACTTTCTGGACTCCATGTTGACCCGTGAGCCGCAGCAGAGATCCAGCGCATCTGACCTGCTCCAGCACCCGTTCCTGCTGCAGTGTTCATCACCCCGCTGCCTCATCCCACTGGTTGAGCAGACCCGCAGACGCACATCCcgctgctga
>TCONS_00035112
TCAAGTCTTCTAGTTCTGGAGGAGTTCACAAGCACGCAGCTCGCGTGAGTCGTGTTACAGAGTAAGAGCGTGGCATTCCTGGACATGAGTTCTGCATCAACTTGAGCTTGATGAAGAGCGGAGACACAGAAGGCGCTGGATGAAGGAGTGTGTCTCACTCAGGTCCTTTACTGCTGCTCAGACTCTGCTGGAGGAAATGAACAGCTGAACTGAGGAAAACACTCGATCTTACAGGCCGCCAGAATGTTccagaggaggaagaagaagaagaggaagttgGAGATCTCCACACCTAAGAACTTCCAGCACCGCGTGCACACTTCTTTTGACCCAGTTCAGGGTTGTTTTATCGGGTTGCCGCCGCAATGGCAGAGCCTCATAGAGACGCTGAAGAGGCCCAAACCAGTGGTGGACCCGTCCAGCTTCACACAGGTGCAGGTCAGACCACAGA
>TCONS_00035113
ATGTTccagaggaggaagaagaagaagaggaagttgGAGATCTCCACACCTAAGAACTTCCAGCACCGCGTGCACACTTCTTTTGACCCAGTTCAGGGTTGTTTTATCGGGTTGCCGCCGCAATGGCAGAGCCTCATAGAGACGCTGAAGAGGCCCAAACCAGTGGTGGACCCGTCCAGCTTCACACAGGTGCAGGTCAGACCACAGAagAGCATCGTTCGTGGAAGTTTCATCGGACACGAGGACTACATTTCAGCGGCGATCGCTCAGATGAGCCGACTCTCCGTCACCAGCTCCAACTCTTTAAGAAGAAGGAGTCCGTCTGTGAGAAAAAGAGCGCAATCATTAGGTCGACTGGGGGAATTAGCAGAAGCAGAGACTTATGAATATGAGGAACTCAATAATACTAACCACAGGAATAGTTCAGATTTACACAGAGGATCCAGACCGATCCAGAGTCCGCAAACTGAGTCTAGACAATCACCAGCAAGAGCTCGATCCGTTCACGAGGCGACCATGTTTACAGGACTGATGCCCAGAGATATCTTACTGCACAGGGCTGGGTGTGAAGGAACCGATAATGCTGGGAATAAACCAAACCAGAGGCCGGTGTCGTGTTTGTACAGCCAAAGTGATGGAGCCAAACTGAACTCGGATCAGCTGAAGATGGAGACGCAGAGGAGGCCGCAGTCTACCTATGACTTTAAGGTCAATTCTCCAAATCTTCCAGCTGCATCTAAACCCAATGGCACCAGCAGTCCAAAACCAGGCCATGGGATAATCTCTATGCAGACGCCTCGCCGTTCCTCCACTGATAACACCCTCAAACTCTCCACTATCCCAGCCGATGTTCCTCCAGCACAGGACAGCCCGTCAGAGCCCAGACAGGCCCCAAGCGGAGCCTCGTCTCCTGGGCTGACAGAGCCcagcgtcacacacacacagttcagagCCGCGCTGCAGATGGTGGTGGATCCGGGAGACCCGCGCTCATACCTGGAGAACTTCATCAAGATCGGGGAGGGCTCGACTGGGGTGGTGTGCATCGCCAGAGAGAAGCACAGCGGACGACAGGTGGCCGTCAAGATGATGGACCTGCGCAAACAGCAGAGGAGAGAGCTGCTCTTCAATGAGgtGGTGATCATGCGGGACTACAGGCATCAGAATGTGGTGGAGATGTACAAGAGTGCGCTGGTTGGTGAAGAGCTGTGGGTGATCATGGAGTACCTGCAGGGCGGCGCTCTCACCAACATCGTCTCAGAGACCAGgctgaCAGAGGAGCAGATAGCAACGGTGTGTGAGTCTGTCCTGCAGGCTCTGTGTTATCTTCACTCTCAGGGAGTCATCCACAGAGACATCAAGAGCGACTCCATCCTGCTGACGTTGGACGGCAGGGTCAAGCTGTCAGACTTTGGCTTCTGTGCTCAGATCAGTAAAGACGTACCCAAGAGGAGGTCTCTGGTCGGGACTCCATACTGGATGGCACCGGAGGTGGTTTCTAAGACGCCGTACGGCACTGAGgtGGATATTTGGTCTCTGGGCATCATGGTGGTGGAGATGGTTGATGGAGAACCTCCGTATTTTAGCGAAACACCAATTTCTGCTATGAAGAGACTGAGAGACGAGCCGCCGCCGACCGCCAGAAACGCCAGCAAGATCTCTCCTGTCCTGCGGGACTTTCTGGACTCCATGTTGACCCGTGAGCCGCAGCAGAGATCCAGCGCATCTGACCTGCTCCAGCACCCGTTCCTGCTGCAGTGTTCATCACCCCGCTGCCTCATCCCACTGGTTGAGCAGACCCGCAGACGCACATCCcgctgctga

Function

symbol description
pak6b Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; protein phosphorylation; and regulation of MAPK cascade. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough).

GO:

id name namespace
GO:0023014 signal transduction by protein phosphorylation biological_process
GO:0032147 activation of protein kinase activity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0031098 stress-activated protein kinase signaling cascade biological_process
GO:0016310 phosphorylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041014-121 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; protein phosphorylation; and regulation of MAPK cascade. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough).

Ensembl:

ensembl_id ENSDARG00000052405

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035111 False 2203 mRNA 0.54 11 53521648 53568849
TCONS_00035112 False 451 mRNA 0.52 4 53522059 53541596
TCONS_00035113 True 1824 mRNA 0.54 8 53541389 53568849

Neighbor

gene id symbol gene type direction distance location
XLOC_017751 bub1ba coding upstream 11675 53474963 ~ 53509973 (+)
XLOC_017750 apobb.2 coding upstream 51396 53439665 ~ 53470252 (+)
XLOC_017749 NA coding upstream 117111 53403053 ~ 53404537 (+)
XLOC_017748 cdc40 coding upstream 119649 53368611 ~ 53401999 (+)
XLOC_017747 gpr6 coding upstream 241901 53278746 ~ 53279747 (+)
XLOC_017753 myh6 coding downstream 8653 53577502 ~ 53583436 (+)
XLOC_017754 slc25a47a coding downstream 59685 53628534 ~ 53641863 (+)
XLOC_017755 NA coding downstream 233672 53802521 ~ 53810931 (+)
XLOC_017756 NA coding downstream 296284 53865133 ~ 53870405 (+)
XLOC_017757 NA coding downstream 329234 53898083 ~ 53903358 (+)
XLOC_017744 NA non-coding upstream 369225 53135436 ~ 53152423 (+)
XLOC_017743 NA non-coding upstream 571817 52944123 ~ 52949831 (+)
XLOC_017742 CU207296.1 non-coding upstream 601662 52919856 ~ 52919986 (+)
XLOC_017740 NA non-coding upstream 850456 52670859 ~ 52671192 (+)
XLOC_017763 NA non-coding downstream 489147 54057996 ~ 54059266 (+)
XLOC_017765 CU633785.1 non-coding downstream 520131 54088980 ~ 54107941 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000029_08533907_08555317 PAK6 coding CI01000029 null 8533907 ~ 8555969 (+)