XLOC_021476 (pofut1)


Basic Information

Item Value
gene id XLOC_021476
gene name pofut1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 7692042 ~ 7709134 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00042685
gggatagAGAGTGAACAGCGATGGCGGCGAGACCAAAGCACCTGAAACttttcattgtaacttatttGCACACATCACTCATTTTCCTCAATGTATTTATCGACGCTACAGACGTGACGTGGGATGAAAATGGATACATTCTGTACTGTCCGTGCATGGGTCGCTTTGGAAACCAGGTGGATCACTTTCTTGGATCACTGGCTTTTGCTAAAATGCTGAACCGAACTCTCGCGGTTCCGCCGTGGATTGTTTACCGCCATCACTCGCCGCCTTTTGCTAATGTGCATGTTCCATACAGTGAGTATTTCCAGCTTGAGCCGCTGAAGCAGTACCACCGTGTGGTGAGTCTGGAGGACTTCATGGAGCACTTGGCTCCTAAACACTGGCCTCATGGTCAGAGAATCGCTTACTGCTTTGAGTCCGCAGCGCACAGGAGCCAGGACAAAAAGAGTTGTCCTATGAAGGATGGAAATCCTTTTGGTCCGTTCTGGGACCATATTGGAGTGGACTTTGACCGATCCGTTCTTTTTGGAGGTCTTTCATTCAGCTCCTACTACCAGCCACACTGGATTAAAAGGTTTCCGCCAAAGGAGCATCCGGTTCTTGCTCTTCCAGGAGCCCCGGCGCAGTTTCCTGTGTTGGAAGAGCACATTGGTCTGCAGCAGTTTGTGGTTTGGTCTGACAGAATTGTACAGGAAGGAGAAGGTCACATCAGAAACCTGCTGAACAGACCCTACGTGGGCATCCATCTGAGGATCGGCTCTGATTGGCAAAACGCCTGCAAGCTGTTGAAAACGGGTGATACTGGTCCACACTTTATGGCGTCTCCACAGTGTGTAGGATATGACCGTCAGACTGCTCTGCCACTGACCATGAACATGTGTTTACCTGATCTGACGGAGATCCGCCGAGCTGTGAAACTCTGGGTGAAGAACACTGGTGCTCAGTCTGTATACATCGCCACAGACTCAGAGTCGCACACCACAGAGATTCAGAAACTCTTCAAGGGCAAGGTGAAAGTGGTGAGCTTGCAGCCGGACACTGCTCAGGTTGACCTGTACATCCTCGGACAGGCTGATCACTTCATCGGCAACTGTGTTTCATCCTTCTCTGCCTTTGTCAAAAGAGAGAGAAACATTCACGGGAGACCCTCGTCTTTCTTTGGACTGGACTACCCTGGAAAAAAGAACAGAAATGAAGAACTCTAATGAATCTAATGAAACTCTAATGTTTCTCATTCGTTTTTGAACAAGGCAATTTGGATACACACCTCAAGTACGTAAAGGAAGGGAGAAGTTGATTCATATCTCCCAATGTTGCACTACTAGCTGTACTTTGAGCAGTCAAACCAGAACCAAATTCTCCATTTCGTATTACTGCAAGTTTCTTCCAGAAACACATCAGGGTTTATTGTGACATATCAATTGATTTGTACTGGAATGTTTGTGTAGACTCATTCACAATTTTCGAGGATGGAAACTGACCAGTAAGGGTTAGGAatgctggaaaactgtaaccatttacttcatagtaaaaacaaatactatgg

Function

symbol description
pofut1 Predicted to enable peptide-O-fucosyltransferase activity. Predicted to be involved in protein O-linked fucosylation and regulation of Notch signaling pathway. Predicted to act upstream of or within Notch signaling pathway and fucose metabolic process. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1).

GO:

id name namespace
GO:0007219 Notch signaling pathway biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0006004 fucose metabolic process biological_process
GO:0008417 fucosyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0016757 transferase activity, transferring glycosyl groups molecular_function
GO:0046922 peptide-O-fucosyltransferase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040303-2 Predicted to enable peptide-O-fucosyltransferase activity. Predicted to be involved in protein O-linked fucosylation and regulation of Notch signaling pathway. Predicted to act upstream of or within Notch signaling pathway and fucose metabolic process. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1).

Ensembl:

ensembl_id ENSDARG00000008953

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00042685 True 1549 mRNA 0.47 7 7692042 7709134

Neighbor

gene id symbol gene type direction distance location
XLOC_021475 tm9sf4 coding upstream 113150 7548797 ~ 7578892 (+)
XLOC_021474 hck coding upstream 146082 7505943 ~ 7545960 (+)
XLOC_021473 rbbp8l coding upstream 188025 7471072 ~ 7504017 (+)
XLOC_021472 NA coding upstream 256726 7402807 ~ 7435316 (+)
XLOC_021471 gata5 coding upstream 301014 7379728 ~ 7391028 (+)
XLOC_021477 kif3b coding downstream 1313 7710447 ~ 7736719 (+)
XLOC_021478 rgs19 coding downstream 970082 8679216 ~ 8699993 (+)
XLOC_021479 NA coding downstream 1078861 8787995 ~ 8811654 (+)
XLOC_021480 sox18 coding downstream 1088009 8797143 ~ 8799880 (+)
XLOC_021481 xkr7 coding downstream 1280034 8989168 ~ 9015026 (+)
XLOC_021470 si:dkeyp-73a2.2 non-coding upstream 336262 7350170 ~ 7355780 (+)
XLOC_021469 NA non-coding upstream 485847 7204539 ~ 7206195 (+)
XLOC_021467 NA non-coding upstream 826086 6851931 ~ 6865956 (+)
XLOC_021466 BX005466.1 non-coding upstream 866240 6825688 ~ 6825802 (+)
XLOC_021488 CU137717.1 non-coding downstream 1598440 9307574 ~ 9308561 (+)
XLOC_021490 NA non-coding downstream 1687534 9396668 ~ 9403617 (+)
XLOC_021493 CR388392.1 non-coding downstream 1909079 9618213 ~ 9618335 (+)
XLOC_021494 CU466281.1 non-coding downstream 2018276 9727410 ~ 9727432 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000021_04822864_04825902 POFUT1 coding CI01000021 null 4822166 ~ 4825902 (-)