XLOC_022238 (dnmt3bb.1)


Basic Information

Item Value
gene id XLOC_022238
gene name dnmt3bb.1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 17011454 ~ 17101360 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00043899
CGATTCGAGACCCGGGAAAAGTCACGCCTGACTGTAGTAGAGGCGAAAGACCGAGCGGTCCTTGAGAACGAGACTCCATTTACATATTCACCCTTGGGCTTTAAAGGCGTGTGCATCAGCAAACATTAGCCTGACATACCTCGGCACTTTGGCAGTGGACTACTCTTACGGCACCTTCAATCTCTGCTATCAAGCGTTAACTAATATCAGTACTTCTCCACAAGACAGGATGaggaaggaagaaataaaaaagtcGACTGAAATAGTGATGCCATCCAACAAGTACCCCTCCGCGGAAAGTGACAAGATGACTGCCACGGCTGCCATGAATCGAGACACATCTGTGGGCGATGGATTGTCAGAGAATGACAGCGGTCTGGAAATGACCAGTGAAAACAGCCCCCTGACCCCAGCAGAGCCCCCGTCACCATTCTGTCCCAAACAGAACGGTGGTGCAGCCTCACCCGCAGATGAGAGTGTGAACAGCATCAGACGAAAGAGGTCTCGTAAGCGCTCTGACACTGAGGAAGACAGTGCCTGGGATTCCTCCTACAGCGAGGAAAAGGCTGAGGTTGGGTCGGGTTGTGAGACAGGTCTCCGGCAAAGGCCTCGCCCCAGGACTATTTTCCAGGCAGGACTAACAGCTCACAGTAAACCCCGCAGCAGAGAAAGGGGACACAGCAAAGAGGATCACAGCGACCTGgttgCTAGTGTCCCTGAAGGTCCAGCACTGGAGCTCATGGAGCAGGACTCTAAAGACTCTGCACAGAGCAGCACCACATCCACCTCCACTACTGAAACAGCCAGTCAACCTGAATACAAGGATAATAAGGGCTTTGGTATTGGAGAGTTGGTCTGGGGCAAGATAAAGGGCTTCTCGTGGTGGCCAGGGATGGTGGTGACCTGGAGAGCAACTGGGAGGAGGCAGGCCTCCCACGGCATGCGTTGGCTACAGTGGTTTGGTGATGGGAAATTCTCAGAGGTGTCTGCTGACAAACTCGACTCTATCACAGCCTTCCCAAAATTTTTCAACCAGTCATCCTACACCAAGCTGGCCTCCTACCGTCGAGCGATCTTCCAGGCCCTTGAGGTGGCTAGTTTACGTGCAGAGAAGACTTTTCCTCCATCTGAGGCAGACAGTCTTGAAGAACAGGTAAAGCCCATGCTCGACTGGGCTCACGGTGGCTTCCTGCCCAAGGGTCAGGAGGGTCTTAAACCCAAAGAGAATGCAGAGTATTGTGTTTTCCCCCTGGCCTCAGAGAGCTCAACGCTGCTGGAATCCAGCCCTCCAGAGTTTCCCCCCTCTGCCAAAAGAGCTCGACTCCCCCTTAATAAGGCTAAACCTGGCATTGAGGAGGTCTACAGCAGAGaacaaATGGTCAATGAAGTTTTGAAGAATCACAGAAGTATAGAAGAGTTCTGCCTCTCTTGCGGAAAGACAAGAGTTGCGACCTTTCACCCGTTGTTTGAAGGAGGCCTTTGCCTAACATGCAAGGATGCTTATCTAGAGAACTCCTACATGTACGATGACGATGGCTACCAATCGTACTGCACCGTGTGTTGTGGCGGCCGTGAGATGCTGCTGTGTGGAAACGCCAACTGCTGCAGGTGTATTTGTGTGGACTGTCTGGATATATTAGTGGGAGCAGGAGCAGCTAACAGTGCCCGTAATCTGGACCCGTGGCGCTGCTACATGTGCCAACCTCTGCAGCAATATGGCGTCTTAAAGAAACGTCATGACTGGAGCCTCAAACTGCAAGAGTTTTTTGTCAATGACAGCGGCCAGGAATTTGAAAGTCCAAAGATTTACCCTGCAGTCCCAGCAGAGCAGAGACGGCCAATCAGAGTGCTTTCGTTGTTTGATGGCATTGCCACAGGTTATCTGGTGCTTCGGGACTTGGGCTTCAAGGTTGATTTGTACATTGCGTCAGAAGTATGCGAGGACTCGATTTCAGTGGGAGCTGTCCGGCATGAAGGAAAAATCCAGTATGTGCATGATGTTCGCAACATCACCAGAAAAAACATTGCTGAATGGGGGCCCTTTGACATGGTGATTGGTGGAAGTCCCTGTAATGACCTTTCAATTGTCAACCCTGCTAGGAAAGGTCTGTACGAGGGGACTGGACGGCTGTTCTTTGAGTTTTATCGCCTCTTGAGTGAAGCGAAACCAAAGGAAGGGGAAGACCGGCCTTTCTTCTGGATGTTTGAGAATGTGGTGGCCATGAGCGTCAATGACAAGAGAGATATCTCACGCTTTCTAGAGTGTAATCCAGTGATGATTGACGCCATAGAGGTGTCGGCTGCTCACAGGGCACGCTATTTCTGGGGCAACCTGCCAGGAATGAAGAGGCCTCTGTGTGCCTCTGGGATGGATAAATTAGAGCTTCAGGACTGTTTGGAACATGGCCGTGTTGCCAAGTTCGGGAAGGTACGTACCATCACAACACGCTCCAATTCCATCAAACAAGGCAAAGACCAGCATTTCCCTGTCATGATGAATGGCAAAGAGGATATCCTGTGGTGCACAGAGCTCGAGAGGATTTTTGGCTTTCCTGTTCACTACACAGATGTCTCCAACATGGGCCGTGGCGCCAGACAGAAGCTGCTGGGGCGATCCTGGAGCGTTCCAGTTATCCGACATCTGTTCGCCCCACTGAAGGACTACTTTGCGTGTGAATAGCACATGTAGTCCGCGTTCAGTTAATCTAAAGCAAACACAAAGTACAAGACCAAATGTCCTCAAAAAGGAGCTCTTAGAGACCCACAAATTTGACAAGACCATCTCAGCTTTGGAAAAACAAGCATGAGAAGCTGTGACTTGAGGTCGAGGGTAGTGTTGAGCAACAGGCCAAACTCAAGGTAGACACTGTGATGCTAAGAGCGAAAACACAGTTAGCTTTTGTACTCGACGTTTTTAAAATGGATGTGCCTGAAAACGGCCAGGGTTCACATGCGGGTAGATTAATCTTTTATtatcatgagaaaaaaaaaataataatttttaatcgAACAAAACATTTTAGTTTCTTCCAGAGCAAATCTGGCTAAGCAATGCTGAAATGTGTGAACTTTAAATTCCTCATTCATGCATGTGACTCATGTTCACCATATTATCGGGGTGAaagaaatacttgaaaaattgtATCAATGCAAACTTCCAAACACCAAGCTGTGAACCCTTAAAGAATGCGTTTTAGAGGATGCGTTCAAATAGTCGATCGCCCCTATTTGTGTTTCATAAAGCCTCCATGCCCTCTGTATCGTTGCACAATAACAGTAACCAGAAGGTGTTTTCTTTTATATCATTAGCAGAACTCGAGGGCATTAGCCTGTTAAACATTACAGTTCTTTCCTTAAGTAATTTGTGTCGTTCAAGCAATCGTTCAAGATAGAGATCAGTGTACTGTATTTTAACTTTGAAAGTAATGTTTACaaactttaacacatttcaacAAGTTTTTAGAGCTTTCTTACCAtactttctttgttttttagCCTGCTTTAGATGTAAAATGTTTGATGctgttgtttttaatattcaCTGTTGCTGCCAACAATAACAAACGCATTGTATTATTGTAGCACTCTGATGCCTTAATGTGTGGTGCCTTTTGAAGAGAACAGATACAGCCTGCCATACGGGCGTTGCGAAGAAACTTTCTGCCtttgtttgctgta

Function

symbol description
dnmt3bb.1 Predicted to enable DNA (cytosine-5-)-methyltransferase activity; DNA binding activity; and metal ion binding activity. Acts upstream of or within several processes, including DNA methylation on cytosine within a CG sequence; hematopoietic stem cell homeostasis; and regulation of hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; hematopoietic system; immature eye; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune disease (multiple); carcinoma (multiple); immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta).

GO:

id name namespace
GO:0006306 DNA methylation biological_process
GO:1902036 regulation of hematopoietic stem cell differentiation biological_process
GO:0010424 DNA methylation on cytosine within a CG sequence biological_process
GO:0061484 hematopoietic stem cell homeostasis biological_process
GO:0010468 regulation of gene expression biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0032259 methylation biological_process
GO:0009008 DNA-methyltransferase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0008168 methyltransferase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050314-1 Predicted to enable DNA (cytosine-5-)-methyltransferase activity; DNA binding activity; and metal ion binding activity. Acts upstream of or within several processes, including DNA methylation on cytosine within a CG sequence; hematopoietic stem cell homeostasis; and regulation of hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; hematopoietic system; immature eye; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune disease (multiple); carcinoma (multiple); immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta).

Ensembl:

ensembl_id ENSDARG00000036791

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00043899 True 3678 mRNA 0.48 22 17011454 17101360

Neighbor

gene id symbol gene type direction distance location
XLOC_022237 NA coding downstream 6671 16961269 ~ 17004783 (-)
XLOC_022236 cdc42l2 coding downstream 50482 16956185 ~ 16960972 (-)
XLOC_022235 NA coding downstream 158507 16850836 ~ 16852947 (-)
XLOC_022234 si:dkey-63j12.4 coding downstream 167805 16840572 ~ 16843649 (-)
XLOC_022233 AL732515.1 coding downstream 265031 16744782 ~ 16746423 (-)
XLOC_022240 BX927275.3 coding upstream 74744 17176104 ~ 17176218 (-)
XLOC_022241 BX649300.1 coding upstream 252793 17354153 ~ 17355702 (-)
XLOC_022242 ppdpfb coding upstream 326478 17427838 ~ 17429775 (-)
XLOC_022243 tpd52l2b coding upstream 329985 17431345 ~ 17451264 (-)
XLOC_022244 trim101 coding upstream 353331 17454691 ~ 17470146 (-)
XLOC_022231 NA non-coding downstream 302216 16693578 ~ 16709238 (-)
XLOC_022228 NA non-coding downstream 363415 16644124 ~ 16648039 (-)
XLOC_022247 NA non-coding upstream 556634 17657994 ~ 17839198 (-)
XLOC_022248 CU570795.1 non-coding upstream 581458 17682818 ~ 17682932 (-)
XLOC_022251 NA non-coding upstream 779663 17881023 ~ 17885851 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00008057 NA coding CM030123.1 CM030123.1 40896616 ~ 40922814 (+)