XLOC_022811 (fen1)


Basic Information

Item Value
gene id XLOC_022811
gene name fen1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 11908480 ~ 11921184 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045356
CTGTATTTAGAATTCGCGCGAAATAGACGAGGCTTTTCCGCGCGGTTGTAGTCGTGTCCAAGTGTGAAAGACTGAGAAGTGGATGCTGAAGCCCATATTTTATTAGTTTCTGATAGTAACAGTTTATCACTATGGGAATTCACGGACTTGCAAAGCTCATTGCAGATCACGCGCCTTCGGCTATTAAGGAGCATGAAATCAAAAGCTACTTTGGACGGAAGATTGCTATAGATGCCTCCATGTGCATCTACCAGTTTTTGATTGCGGTTCGACAGGACGGTAATGTGTTGCAGAATGAAGATGGAGAGACCACTAGCCACCTCATGGGCATGTTCTACAGGACCATCCGAATGCTGGAAAGCGGCATCAAGCCGGTTTATGTTTTTGATGGGAAGCCACCTCAGCTCAAGTCAGGAGAGCTTGAGAAGAGAGTTGAGAGACGAGCAGAGGCTGAGAAACTTCTAGCTCAGGCACAAGAAGCAGGTGAGCAGGAAAATATTGACAAGTTTAGTAAACGACTAGTGAAGGTAACCAAACAACACAATGAGGAATGCAAGAAATTACTTTCTCTAATGGGAGTCCCATACATTGAGGCTCCATGTGAGGCAGAGGCGAGTTGTGCTGCTCTGGTGAAAGCAGGGAAGGTTTATGCCACAGCAACAGAAGATATGGACGGTCTGACATTTGGAACAACGGTCTTATTGAGGCATCTAACAGCTAGTGAAGCAAAAAAGCTCCCCATCCAAGAGTTTCACTTCAGTCGTATTCTGCAGGATATGGAGCTGACGCATCAACAGTTCATCGACCTGTGTATCCTGCTGGGCTGTGACTACTGTGGCACTATAAAGGGAATCGGACCCAAGAGGGCCATTGACCTAATTAAACAGCATGGCTCTATTGAAGAAATTCTGGAGAATATTGACCCAAATAAGCACCCTGCTCCAGAGGACTGGCTGTATAAAGAGGCTCGGGGTCTCTTCTTGGAACCTGAGGTCGTGGATGGCACCTCTGTCGATCTGAAGTGGAATGAACCTGATGAGGATGGGCTAATTCAGTTCATGTGTGCTGAGAAGCAGTTCAGTGAGGATCGTATCCGTAACGGCTGTAAGAAGATCACAAAGAGCAGACAAGGCAGCACCCAGGGCCGACTGGACACATTCTTTACTGTAACCGGATCAATCTCTTCTAAGCGTAAGGAGCCTGAAACAAAGGGATCtgccaaaaagaaacaaaagacaAGTGCTACGCCAGGCAAATTTAAGAAGGGCAAATGAAAGGGATTTCTGCAAAATGAGTTTATTTCATATCGTCACTTCTTattgctaaaaaaacaaaaaagtcaacaTTACCTTTTGAGTATTTTAGGGGAACTATGTTTTAAATACCCTGTTGTGCTGTCTATCTTGAATAAAGATAAGTATTTAATG
>TCONS_00045357
GTTTCTGATAGTAACAGTTTATCACTATGGGAATTCACGGACTTGCAAAGCTCATTGCAGATCACGCGCCTTCGGCTATTAAGGAGCATGAAATCAAAAGCTACTTTGGACGGAAGATTGCTATAGATGCCTCCATGTGCATCTACCAGTTTTTGATTGCGGTTCGACAGGACGGTAATGTGTTGCAGAATGAAGATGGAGAGACCACTAGCCACCTCATGGGCATGTTCTACAGGACCATCCGAATGCTGGAAAGCGGCATCAAGCCGGTTTATGTTTTTGATGGGAAGCCACCTCAGCTCAAGTCAGGAGAGCTTGAGAAGAGAGTTGAGAGACGAGCAGAGGCTGAGAAACTTCTAGCTCAGGCACAAGAAGCAGGTGAGCAGGAAAATATTGACAAGTTTAGTAAACGACTAGTGAAGGTAACCAAACAACACAATGAGGAATGCAAGAAATTACTTTCTCTAATGGGAGTCCCATACATTGAGGCTCCATGTGAGGCAGAGGCGAGTTGTGCTGCTCTGGTGAAAGCAGGGAAGGTTTATGCCACAGCAACAGAAGATATGGACGGTCTGACATTTGGAACAACGGTCTTATTGAGGCATCTAACAGCTAGTGAAGCAAAAAAGCTCCCCATCCAAGAGTTTCACTTCAGTCGTATTCTGCAGGATATGGAGCTGACGCATCAACAGTTCATCGACCTGTGTATCCTGCTGGGCTGTGACTACTGTGGCACTATAAAGGGAATCGGACCCAAGAGGGCCATTGACCTAATTAAACAGCATGGCTCTATTGAAGAAATTCTGGAGAATATTGACCCAAATAAGCACCCTGCTCCAGAGGACTGGCTGTATAAAGAGGCTCGGGGTCTCTTCTTGGAACCTGAGGTCGTGGATGGCACCTCTGTCGATCTGAAGTGGAATGAACCTGATGAGGATGGGCTAATTCAGTTCATGTGTGCTGAGAAGCAGTTCAGTGAGGATCGTATCCGTAACGGCTGTAAGAAGATCACAAAGAGCAGACAAGGCAGCACCCAGGGCCGACTGGACACATTCTTTACTGTAACCGGATCAATCTCTTCTAAGCGTAAGGAGCCTGAAACAAAGGGATCtgccaaaaagaaacaaaagacaAGTGCTACGCCAGGCAAATTTAAGAAGGGCAAATGAAAGGGATTTCTGCAAAATGAGTTTATTTCATATCGTCACTTCTTattgctaaaaaaacaaaaaagtcaacaTTACCTTTTGAGTATTTTAGGGGAACTATGTTTTAAATACCCTGTTGTGCTGTCTATCTTGAATAAAGATAAGTATTTAATGATTCCAGTGTGGTCTATTTTTTGGTGTTCATCTTCAAAGAATTGTGATCTTTGTTGGATGCGACACATTGCTGATGTTCACGATGTACAAGCAAAAGGCTGACAACACCAATGAATTTTTGTATTTTGCCCTACAGCATTTTCAGCCCACAAGCTTTTCTTAGCTCTTCACCATTCTGTCAGAGCAAAAATAATTAACTCCAAACTAAAGCCTCTCTGTTGCCTGAATTTGGGTTGCTAAACAGGTTTGCATATGAGGAAGTACAACAGACTGCTCTAAGGTATACAAATCTCATTTAGAATATTTTATTGCAGAATTAAGACAATTTTAATAATGTTGATGTAGAGCATTTTGTAGTTTCAATGCGTTTGACTTTGGGTATTgattgttttaatgttgtaatgtaCAATTCTTAACCTGTTACAGAGTAGGAGCCCCTGGAAAGAGTTAACTGCAGCATCACTTCTTTTGTCTGCAAACTACTAGTTAGACTGATAGAAATCCACAGCTCAGTCAGGAAATTGTGTCAGAGCCTCCAATTCACTGAATGATAGCGTATACTGCTGTAGGTGAGTTGTTATTTTGCAAACGTTTGACAAATTCAAGTTAAAAACTGGACATACCATAGCTGATTAGAGACAACTGTTTCTATGTCTGTTTGTACTTTCAGCAGTCGAGATGTCCTCCTTGCCTTTAATGGTTTTTCTCTTTTTCCCTTATGCGTTTTTACTAAAATGTACAGGTGAGTCAGTGCCTGAAGTGTACAGCAAAAACTGATTTGAAAACATTTGTATAATAATTGTGAGGGGGGAAGTATTGAAGTTGTTTTAGCTTGTATAACCTTTCTGTTTTCAGAACAATATCATGCACGTTTACCTAGCAATATAACAGGGCTTAGTGACTCTTGTTTGAGGATACCCTGTGAATTTGAGGCAGACAGCACACAGATGAACaatggaaaaatatttgttttttgggtAAAAACAACCCATAGTATCCAAGTTCCAGCCAATGTGGTTTATAATGGAACAACCAACATGACTAAAGGATTTAGCCATATAGAGATAACTGGAAATCTTGGCAAGAATGATTGTACGacagttttttacaatgtcaTGAAAAATCATTCAGACAACTACTACTTTAGAGTTGAAATCGAACCACAACAATGGTATTTCTCATACACCAATCCTGTCTACATTTCGGTCTCAGGTAAGTGGGTCTGCTTTGTAAACATACTagtgtaatgtttaaattatgtttagaaatgtgctgaaaaaaatcttctctccaataaacaaaaattaggggaaaaaactagggctaataattctgacttcaacagtgtgtgtgtgtgtgtgtgtgtacacgcaCACGTACATAGtggaagttagaattattagcccctgtttattttttccccaatttctgtttgacgaaaatatttttttcagcgcatttctaaacataatagttataataactgatttatttaatctctgcattgatgacagtacagaatattttcctagatattttaaagatgcttttatacagcttaatttgacatttaaaggctttactaggttaattaggcaggttagagtaattatgcaagttattgtataacagtggtttgttctgtagactatcgaaggaAATGGCTTGAAGTGGCTaaatattttgaccttaaaatgttttttttttttaaaaaaggggggtaataattctgacttcaactgtatatatatatatatatatatatatatatatatatatgtatatacatgtgtatatatgtatgtgtgtgtgtgtgtatatatatatatatatatgtgtgtgtgtgtgtgtatatatatatatatatatatatatatttatatatatatttat
>TCONS_00046944
TGCTAAACAGGTTTGCATATGAGGAAGTACAACAGACTGCTCTAAGGTATACAAATCTCATTTAGAATATTTTATTGCAGAATTAAGACAATTTTAATAATGTTGATGTAGAGCATTTTGTAGTTTCAATGCGTTTGACTTTGGGTATTgattgttttaatgttgtaatgtaCAATTCTTAACCTGTTACAGAGTAGGAGCCCCTGGAAAGAGTTAACTGCAGCATCACTTCTTTTGTCTGCAAACTACTAGTTAGACTGATAGAAATCCACAGCTCAGTCAGGAAATTGTGTCAGAGCCTCCAATTCACTGAATGATAGCGTATACTGCTGTAGCAGTCGAGATGTCCTCCTTGCCTTTAATGGTTTTTCTCTTTTTCCCTTATGCGTTTTTACTAAAATGTACAGAACAATATCATGCACGTTTACCTAGCAATATAACAGGGCTTAGTGACTCTTGTTTGAGGATACCCTGTGAATTTGAGGCAGACAGCACACAGATGAACaatggaaaaatatttgttttttgggtAAAAACAACCCATAGTATCCAAGTTCCAGCCAATGTGGTTTATAATGGAACAACCAACATGACTAAAGGATTTAGCCATATAGAGATAACTGGAAATCTTGGCAAGAATGATTGTACGacagttttttacaatgtcaTGAAAAATCATTCAGACAACTACTACTTTAGAGTTGAAATCGAACCACAACAATGGTATTTCTCATACACCAATCCTGTCTACATTTCGGTCTCAGGTAAGTGGGTCTGCTTTGTAAACATACTagtgtaatgtttaaattatgtttag

Function

symbol description
fen1 Predicted to enable metal ion binding activity and nuclease activity. Acts upstream of or within retina development in camera-type eye. Predicted to be located in mitochondrion; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; head; pectoral fin musculature; and proliferative region. Orthologous to human FEN1 (flap structure-specific endonuclease 1).

GO:

id name namespace
GO:0006974 cellular response to DNA damage stimulus biological_process
GO:0043137 DNA replication, removal of RNA primer biological_process
GO:0006260 DNA replication biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0006281 DNA repair biological_process
GO:0006284 base-excision repair biological_process
GO:0005634 nucleus cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005730 nucleolus cellular_component
GO:0005739 mitochondrion cellular_component
GO:0008409 5'-3' exonuclease activity molecular_function
GO:0030145 manganese ion binding molecular_function
GO:0004518 nuclease activity molecular_function
GO:0004519 endonuclease activity molecular_function
GO:0004523 RNA-DNA hybrid ribonuclease activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004527 exonuclease activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016788 hydrolase activity, acting on ester bonds molecular_function
GO:0048256 flap endonuclease activity molecular_function
GO:0017108 5'-flap endonuclease activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0000287 magnesium ion binding molecular_function

KEGG:

id description
ko03030 DNA replication
ko03410 Base excision repair
ko03450 Non-homologous end-joining
ko03032 DNA replication proteins
ko03400 DNA repair and recombination proteins
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-031112-11 Predicted to enable metal ion binding activity and nuclease activity. Acts upstream of or within retina development in camera-type eye. Predicted to be located in mitochondrion; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; head; pectoral fin musculature; and proliferative region. Orthologous to human FEN1 (flap structure-specific endonuclease 1).

Ensembl:

ensembl_id ENSDARG00000011404

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045356 False 1427 mRNA 0.45 12 11908480 11919291
TCONS_00045357 False 3215 mRNA 0.38 11 11908833 11921184
TCONS_00046944 True 817 lncRNA 0.36 3 11919526 11920556

Neighbor

gene id symbol gene type direction distance location
XLOC_022810 BX005153.1 coding upstream 283613 11622196 ~ 11624867 (+)
XLOC_022809 BX005153.3 coding upstream 294107 11614257 ~ 11614373 (+)
XLOC_022808 NA coding upstream 309951 11597090 ~ 11598529 (+)
XLOC_022807 BX005153.2 coding upstream 342038 11564896 ~ 11566442 (+)
XLOC_022806 NA coding upstream 368765 11539508 ~ 11539715 (+)
XLOC_022812 NA coding downstream 21680 11942864 ~ 11943328 (+)
XLOC_022813 NA coding downstream 35814 11956998 ~ 11958133 (+)
XLOC_022814 NA coding downstream 133846 12055030 ~ 12061352 (+)
XLOC_022815 ccr9b coding downstream 153156 12074340 ~ 12085001 (+)
XLOC_022816 NA coding downstream 174346 12095530 ~ 12102138 (+)
XLOC_022817 CU929203.1 non-coding downstream 208542 12129726 ~ 12132445 (+)

Expression


Co-expression Network