XLOC_002339 (mmp13a)


Basic Information

Item Value
gene id XLOC_002339
gene name mmp13a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 38610741 ~ 38620514 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004444
CGTTTAAAAATGGATTTTCTtaatgaggtgtactcatttatgtttagccctgtatatatgcttatatactttaaaaataaaatatatcctTTTTAGTATTATGCTGTGTGTAGTGTGGGACATGTCTCCCTGATTTCCTCTCCGGTGATGAAAGGTGTGATAGTGTATTTGTGACTCAGTGTTGCGTTGCACAATCAGTGCTTCTGTGGTGTATAAAAGAGTGGAGAAAACAGCAGTCTGCATCAGTTTCTTGAAGGAGAAGGAAAGCAAacatgaagacctgcttcaggcTGTGTGTTTTCATCACTCTGCTGTTTTCAGGCCACAGCAGCCCGATCGCGCCGCCTGCTGGAGGAGACCAGGACAAACTCGCGGAGAATTACCTGACCCGACTGTATGGGTTGCCGAAACCTGCACAGAACCCGAGCCCGTCTGGTGGTGAGAAACGTTCCAGTGATATGAGACTGAGGCTCAAGGAGATGCAGCAGTTTTTTAAACTTAAGGTGTCTGGAAAGCTGGACCAGGAGACGCTGGAGGTGATGAAGAAGCCCCGCTGCGGAGTTCCAGACATCAAGGCCTACTCAACCTTTGCTGGAGACTACAAGTGGAAAAAACATCAGCTGACCTACAGGATTGAGAACTACACCCCTGACATGTCAGTGGCAGAGGTGGATGACTCCATCAGTAAAGCTCTGAAGGTGTGGGCTGACGTCACTCCACTGAGATTCACTCGCATCTACAGCGGCACAGCAGACATCATGATCTCCTTCGCCACTGGAGATCATAGAGATGGCTACCCATTTGATGGACCCAATGGATTTCTGGCTCATGCCTTTCCTCCATTTGAGGGCATTGGTGGCGACGCTCATTTCGACGATGACGAGACATTCAGTTACAGATCTCCTCAATATTACAATCTGTTCCTGGTGGCGGCCCATGAGTTCGGACACTCTCTAGGTCTGGAACACTCGCAGGATCCCGGTGCACTCATGTATCCCACCTACGTATACAGAGACGTCGATAGATTCGTCCTCCCTCGAGATGATGTCAATGGAATCCAGTCACTTTATgGCCCAAACACTGACGTCAATACCGATGATTCAAAACCAACCCCACCAGTTACCCCGAACACATGTGATCCCAATCTGGTCCTGGACGCCGTCACCATGCTCCGTGGAGAGATTATGTTCTTCAAGAACAGCTTCTTCTGGCGCAGTTATCCTCAGAGCGCAGATGTTGAACAACAACTCATTAAAAGCTTCTGGCCTGAGGCACCTGATAACATCGATGCCGCTTTCGAGAGTGTCATGCAGGACAAAGTCTTCCTGATCAAagGTGAGAAGGTTTGGGCTCTCTATGGCTATGATATGGTGCAAGGCTATCCCAAGAGTCTCAGCATGTTCCGTCTGCCGAAAAATGTGAGGAAAATCGACGCAGTCCTCTACAAGGAAGACAGCAACACAATCCTCTTTTTCGCCAACAACCAGGTTTACAGTTATAATGAAGGAATAAGGCAAATGGATAAAGGTTTTCCTAAACCAGTGGAGGAGGTTTTCCCTGGAATGACCGGGAAGGTCACCGCAGCCTTCCAGTACAGAGGTTTAAACTACCTCTTCAGTGGATCAAAGATGCTTGAGTTTGGCTCCAACAACAGGCTGTTCCGCGTCCTGAACAACAATTATTTCCTGCCGTGCAAATAATCTTGAGCTTTTTTCTTTAATACTTACCGCCTGAAGAAGAATCCGAGCCatcagtattttatattattgagtAACTTATTAACAATTAACTTATTTTACTAAAAGTATTCATGTGATTGTATTATCCTTGAAAATCATTTGTGTGTATGACAATGATCTGATCAATGCAATTTTGAATAAAGGTTTGAGCAATTTGATTAACAGTCTGAACGCTGGTTTTTGAGTCAATGAGAAGTCTGCATCAAGTTAAATTTAGTCTACATTCAGTAGAAATGATATTAATATCAAGTTGAGTGTCTAATTTGACTTGTGTGGgggaaaaagctaaataaataataggTATGATTATTGTGACATGCttattaaattgcattaaaatgaAATCATATTAAACGTAGTTAAACGTAGCTTAACTACACTTCATAACTTCCAAACATAATTACACGTGTGGCAACACCTCCATTAGCTAACTAACAAATAATTATACTAAGCTGCTCACATTACTAAAACTCTTGTAAAGTACACACTAttagccattagcaaaacaagatCTCAGATAATCCAATTCCCATAAAGATCGTTCAAATTCTCACTAAACAATAAACTGAGCAGCACAAGTTGATCTAATAAATCAATCTCTCAATAAAGAGAAAACTAGAACACAGCAATTGCGAACAAAACCTAACGAAGCAAACAAGTGAACAGGCCTGCCGACATAAGTGAGGAGACTGGCTGTGAGACAAGCGCTCCTCCAgaacaatggttctcaaagtgggggtcgggaccccccgaggggtcgcgggacaatgaaggggggtcgcctggtggtttccaaaaatctatttattttcattga

Function

symbol description
mmp13a Predicted to enable metalloendopeptidase activity. Acts upstream of or within macrophage chemotaxis. Predicted to be located in extracellular matrix. Is expressed in several structures, including extension; head; heart; intermediate cell mass of mesoderm; and leukocyte. Human ortholog(s) of this gene implicated in anodontia; artery disease (multiple); osteoarthritis; ovarian carcinoma; and spondyloepimetaphyseal dysplasia, Missouri type. Orthologous to human MMP13 (matrix metallopeptidase 13).

GO:

id name namespace
GO:0048246 macrophage chemotaxis biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0006508 proteolysis biological_process
GO:0030574 collagen catabolic process biological_process
GO:0031012 extracellular matrix cellular_component
GO:0005576 extracellular region cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004222 metalloendopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-031202-2 Predicted to enable metalloendopeptidase activity. Acts upstream of or within macrophage chemotaxis. Predicted to be located in extracellular matrix. Is expressed in several structures, including extension; head; heart; intermediate cell mass of mesoderm; and leukocyte. Human ortholog(s) of this gene implicated in anodontia; artery disease (multiple); osteoarthritis; ovarian carcinoma; and spondyloepimetaphyseal dysplasia, Missouri type. Orthologous to human MMP13 (matrix metallopeptidase 13).

Ensembl:

ensembl_id ENSDARG00000114451

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004444 True 2556 mRNA 0.43 10 38610741 38620514

Neighbor

gene id symbol gene type direction distance location
XLOC_002338 mmp13a coding upstream 8180 38593645 ~ 38602561 (+)
XLOC_002337 LO018336.1 coding upstream 24081 38560032 ~ 38586660 (+)
XLOC_002336 BX000451.4 coding upstream 62536 38548089 ~ 38548205 (+)
XLOC_002335 acer3 coding upstream 66315 38526496 ~ 38544426 (+)
XLOC_002334 serpinh1a coding upstream 89031 38512270 ~ 38521710 (+)
XLOC_002340 mmp30 coding downstream 22790 38643304 ~ 38663746 (+)
XLOC_002341 acat1 coding downstream 43403 38663917 ~ 38698966 (+)
XLOC_002342 CU896636.1 coding downstream 63152 38683666 ~ 38683780 (+)
XLOC_002343 tmprss2 coding downstream 87585 38708099 ~ 38729185 (+)
XLOC_002344 CABZ01051877.1 coding downstream 128752 38749266 ~ 38760444 (+)
XLOC_002333 BX000451.1 non-coding upstream 121912 38488708 ~ 38488829 (+)
XLOC_002332 NA non-coding upstream 177532 38432338 ~ 38433209 (+)
XLOC_002330 NA non-coding upstream 575906 38025045 ~ 38034835 (+)
XLOC_002327 NA non-coding upstream 721180 37865419 ~ 37889561 (+)
XLOC_002346 NA non-coding downstream 463498 39084012 ~ 39087853 (+)
XLOC_002354 NA non-coding downstream 708788 39329302 ~ 39393816 (+)
XLOC_002356 CR854987.1 non-coding downstream 1140240 39760754 ~ 39760879 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000637_00000433_00003236 MMP13A coding CI01000637 null 433 ~ 3236 (+)
rainbow trout (Oncorhynchus mykiss) G880954 NA non-coding NC_048574.1 CM023228.2 33616184 ~ 33621104 (-)