XLOC_026639 (cdk21)


Basic Information

Item Value
gene id XLOC_026639
gene name cdk21
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 39175860 ~ 39180048 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00051896
ATGGCTGACAGCTGGTGGGAGAACTCAGATTATGAAATTCTGGCAGAAATCGGCCAGGGTGCCTACGGGAAAGTGTACAAAGCCAGAGAGAAGCGTGAGCAGCAGCGCCTGATAGCAGTGAAGAGACTGAACATCCCAGAAGAACCTGAGTCCGGCATACCTCAGTTCATGATTCGAGAAGTGGCTCTTCTGCGCAAAATAGAGCACTTCAACCATCCCAACATAGTCAAGTTGATGAGTGTTTCGGCAGGATGGCAGAATCATAAGTTTGACATGACGCTGGTGTTTGAGTATATCGATCAGGATTTGACCACATTTCTCAGTAGGGCTTCAGAGAAAGGCCTTGCAAAGGacaaaataaagGATGTGATGCGTCAGCTGCTCAGCGGTCTTGATTTCCTCCACACCAACTCCGTCATTCACCGGGACCTGAAGCCTGACAATGTGCTCGTGAGCAGTCGAGGGGAAGTCAAGATTGCAGACTTTGGTTTAGCCAGGATATATACCTACCGCATCGCCCTCACTCCATGTgttGTGACTTTGTGGTACAGAGCTCCAGAAGTCCTGCTGCAGTCCAGTTACATGTCTTCAGTGGACATGTGGAGTGCTGGGTGTATCTTTGCAGAGCTGTTTCTCTTAAGGCCTTTGTTTCGTGGCTTCACAGAGATCCAACAGCTGCAAAAGATCTTTGAGGTAATTGGCTTGCCGGGTAAGGAGGACTGGCCTGTGGAAAGCCCAGTCTGCTACAGTCCTGCCTTGGttgaaaaaaaacctgcaacaCAAGTGCTGGCCAGCCTTACCCCTGAGGAGAATGGCTTACTGTCTCAATTTTTGGCATTCAATCCAGTTCATCGCATCTCTGCCTGTGAAGCTTTGGCCCATCCTTACCTGGCAGTCCGCAACTCTGAAGATAAATGACAGATGAGTGAAGAGGGTGGA

Function

symbol description
cdk21 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within spermatogenesis. Predicted to be part of mediator complex. Predicted to be active in nucleus. Is expressed in brain; oocyte stage I; oocyte stage II; ovary; and testis. Human ortholog(s) of this gene implicated in high grade glioma; lung non-small cell carcinoma; pancreatic adenocarcinoma; pancreatic ductal carcinoma; and primary autosomal recessive microcephaly 12. Orthologous to human CDK6 (cyclin dependent kinase 6).

GO:

id name namespace
GO:0051726 regulation of cell cycle biological_process
GO:0007283 spermatogenesis biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0016592 mediator complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004693 cyclin-dependent protein serine/threonine kinase activity molecular_function
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-131121-149 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within spermatogenesis. Predicted to be part of mediator complex. Predicted to be active in nucleus. Is expressed in brain; oocyte stage I; oocyte stage II; ovary; and testis. Human ortholog(s) of this gene implicated in high grade glioma; lung non-small cell carcinoma; pancreatic adenocarcinoma; pancreatic ductal carcinoma; and primary autosomal recessive microcephaly 12. Orthologous to human CDK6 (cyclin dependent kinase 6).

Ensembl:

ensembl_id ENSDARG00000030163

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00051896 True 939 mRNA 0.49 7 39175860 39180048

Neighbor

gene id symbol gene type direction distance location
XLOC_026638 svilc coding downstream 3892 39112898 ~ 39171968 (-)
XLOC_026637 NA coding downstream 62313 39112314 ~ 39113547 (-)
XLOC_026636 NA coding downstream 200162 38971435 ~ 38975698 (-)
XLOC_026635 si:dkey-106c17.2 coding downstream 257143 38912557 ~ 38918717 (-)
XLOC_026634 znf281a coding downstream 391909 38762891 ~ 38783951 (-)
XLOC_026640 retsat coding upstream 1339 39181387 ~ 39190317 (-)
XLOC_026641 RETSAT coding upstream 11767 39191815 ~ 39198113 (-)
XLOC_026642 si:ch211-232p21.6 coding upstream 20034 39200082 ~ 39208714 (-)
XLOC_026643 nmt1a coding upstream 58048 39238096 ~ 39259919 (-)
XLOC_026644 plcd3a coding upstream 80034 39260082 ~ 39305291 (-)
XLOC_026631 BX936420.1 non-coding downstream 646444 38525979 ~ 38529416 (-)
XLOC_026626 NA non-coding downstream 1526471 37634100 ~ 37649389 (-)
XLOC_026625 NA non-coding downstream 1591053 37581522 ~ 37584807 (-)
XLOC_026646 CU464118.1 non-coding upstream 191825 39371873 ~ 39454903 (-)
XLOC_026648 NA non-coding upstream 381736 39561784 ~ 39563301 (-)
XLOC_026651 BX322795.1 non-coding upstream 469397 39649445 ~ 39649562 (-)
XLOC_026653 BX649356.2 non-coding upstream 765817 39945865 ~ 39951527 (-)
XLOC_026654 BX649356.3 non-coding upstream 777310 39957358 ~ 39957474 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000046_04602081_04604842 CDK21 coding CI01000046 null 4602081 ~ 4605621 (+)