Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_026801 |
| gene name | notch3 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007114.7 |
| NCBI id | CM002887.2 |
| chromosome length | 62628489 |
| location | 53526025 ~ 53559581 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| notch3 | Predicted to enable Notch binding activity. Acts upstream of or within several processes, including animal organ development; blood vessel development; and neurogenesis. Predicted to be located in nucleus and plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; pleuroperitoneal region; and vasculature. Human ortholog(s) of this gene implicated in CADASIL 1; infantile myofibromatosis; and lateral meningocele syndrome. Orthologous to human NOTCH3 (notch receptor 3). |
| id | name | namespace |
|---|---|---|
| GO:0002244 | hematopoietic progenitor cell differentiation | biological_process |
| GO:0007219 | Notch signaling pathway | biological_process |
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0030154 | cell differentiation | biological_process |
| GO:0048514 | blood vessel morphogenesis | biological_process |
| GO:0048793 | pronephros development | biological_process |
| GO:0035019 | somatic stem cell population maintenance | biological_process |
| GO:0007275 | multicellular organism development | biological_process |
| GO:0048259 | regulation of receptor-mediated endocytosis | biological_process |
| GO:0097150 | neuronal stem cell population maintenance | biological_process |
| GO:0001840 | neural plate development | biological_process |
| GO:0021654 | rhombomere boundary formation | biological_process |
| GO:0035633 | maintenance of blood-brain barrier | biological_process |
| GO:0043114 | regulation of vascular permeability | biological_process |
| GO:0014003 | oligodendrocyte development | biological_process |
| GO:0035907 | dorsal aorta development | biological_process |
| GO:0050768 | negative regulation of neurogenesis | biological_process |
| GO:0097746 | blood vessel diameter maintenance | biological_process |
| GO:0001889 | liver development | biological_process |
| GO:0050793 | regulation of developmental process | biological_process |
| GO:0061056 | sclerotome development | biological_process |
| GO:0048936 | peripheral nervous system neuron axonogenesis | biological_process |
| GO:0048709 | oligodendrocyte differentiation | biological_process |
| GO:0060842 | arterial endothelial cell differentiation | biological_process |
| GO:0021514 | ventral spinal cord interneuron differentiation | biological_process |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0038023 | signaling receptor activity | molecular_function |
| GO:0005112 | Notch binding | molecular_function |
| GO:0005509 | calcium ion binding | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| id | description |
|---|---|
| ko04330 | Notch signaling pathway |
| ko04371 | Apelin signaling pathway |
| ko04658 | Th1 and Th2 cell differentiation |
| ko04919 | Thyroid hormone signaling pathway |
| ko04320 | Dorso-ventral axis formation |
| ko05200 | Pathways in cancer |
| ko05206 | MicroRNAs in cancer |
| ko05224 | Breast cancer |
| ko05165 | Human papillomavirus infection |
| ko01522 | Endocrine resistance |
| id | description |
|---|---|
| ZDB-GENE-000329-5 | Predicted to enable Notch binding activity. Acts upstream of or within several processes, including animal organ development; blood vessel development; and neurogenesis. Predicted to be located in nucleus and plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; pleuroperitoneal region; and vasculature. Human ortholog(s) of this gene implicated in CADASIL 1; infantile myofibromatosis; and lateral meningocele syndrome. Orthologous to human NOTCH3 (notch receptor 3). |
| ensembl_id | ENSDARG00000052139 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00052132 | False | 11630 | mRNA | 0.46 | 32 | 53526025 | 53559581 |
| TCONS_00052133 | False | 7921 | mRNA | 0.51 | 33 | 53529714 | 53559408 |
| TCONS_00052134 | True | 2521 | mRNA | 0.53 | 6 | 53529716 | 53533128 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_026800 | shfl | coding | downstream | 17445 | 53491105 ~ 53508580 (-) |
| XLOC_026799 | soul5 | coding | downstream | 39856 | 53476155 ~ 53486169 (-) |
| XLOC_026798 | nr5a5 | coding | downstream | 60776 | 53457192 ~ 53465249 (-) |
| XLOC_026797 | NA | coding | downstream | 73243 | 53449116 ~ 53452782 (-) |
| XLOC_026796 | NA | coding | downstream | 293530 | 53230710 ~ 53232495 (-) |
| XLOC_026802 | NA | coding | upstream | 13550 | 53573131 ~ 53589177 (-) |
| XLOC_026803 | rdh8a | coding | upstream | 128064 | 53687645 ~ 53722182 (-) |
| XLOC_026804 | BX004869.1 | coding | upstream | 129729 | 53689310 ~ 53689428 (-) |
| XLOC_026805 | NA | coding | upstream | 282951 | 53842532 ~ 53842784 (-) |
| XLOC_026806 | trip10a | coding | upstream | 871512 | 54431093 ~ 54500354 (-) |
| XLOC_026793 | NA | non-coding | downstream | 449114 | 53074847 ~ 53076911 (-) |
| XLOC_026786 | BX897682.1 | non-coding | downstream | 1308774 | 52215045 ~ 52217251 (-) |
| XLOC_026785 | NA | non-coding | downstream | 1329201 | 52194623 ~ 52196824 (-) |
| XLOC_026811 | NA | non-coding | upstream | 1188815 | 54748396 ~ 54784321 (-) |
| XLOC_026812 | NA | non-coding | upstream | 1231972 | 54791553 ~ 54820900 (-) |
