XLOC_028366 (ptpro)


Basic Information

Item Value
gene id XLOC_028366
gene name ptpro
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 184863 ~ 193762 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055099
ATGATgacattattttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtttcagggagTGTGGTGCTGAAACTTTCGTCAACTTTGCCTCTTTTGAGCGAGACGGGAAACTGCCGTATAACTGGAGCAAAACGGCACTTAAGAAGAGGAAACTGACCAGtccgGTACAGCTCAGTGATTTCGAGGCCTACCTCAAAGACATGGGCAAAGACTCAGCCTACAAGTTCTCCCTGCAGTTCGAGGAGCTGAAGAGTGTAGGTCTGGATTTGTCCCATGAAGCCGCTGATCTGCCCATCAACAGACCCAAGAACCGCTACACCAACATCCTGCCCTatGACTTCAGTCGAGTGAAGCTGATCTCTCTGCACAATGATGAAGGCTCTGATTACATCAATGCTAACTATATTCCCggctaTAACTCTCCACGCGAGTACATCGCCACGCAGGGCCCACTGCCCGACACCAGGAACGACTTCTGGAAGATGGTGCTGCAGCAGAAAGTGCACATCATCGTGATGCTAACACAGTGCAACGAGCGCCGCAGGGTGAAGTGTGACCACTACTGGCCGTTCAGTGATGAGCCGGTGGCGTATGGAGAGATCAGTGTGGAGATGCTGGCGGAGACAGACTCGCCCGAGTGGACCATCAGGAGCTTCAGACTCGCATACgctgaTGAGACTCAGGACGTCCTGCACTTTAACTACACCTCGTGGCCGGATCACGGAGTGCCGACGGTGAACGCCATCGAGAGCATCCTACAGTTCGTGCAGATCGTCCGGCAGCAGGTCAACAGGAGCAAAGGACCCATCGTAGTgcactgcagtgctGGCGTGGGCCGCACCGGCACCTTCATCTCTCTGGACCGGCTGATGCAGCACATTCAGGAGCACGAGTATGTGGACGTGCTGGGGCTGGTGTCCGACATGCGCTCGCACCGACTGTCCATGGTGCAGACTGAGgagcAGTACGTGTTCATCCATCAGTGTGTTCTGCTGAtgtggaagaagaagaagcagcagTCACACACCAGTGACGTCATCTACGAGAACGTCAGCAAGTCCTAa
>TCONS_00055098
ATGATgacattattttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtttcagggagTGTGGTGCTGAAACTTTCGTCAACTTTGCCTCTTTTGAGCGAGACGGGAAACTGCCGTATAACTGGCGCAGGAGTCTCTTTGCGTTCCTCACGCTTCTGCCATCCTGCCTTTGGACTGACTATCTTTTGGCCTTTTATATTAATCCGTGGAGCAAAACGGCACTTAAGAAGAGGAAACTGACCAGtccgGTACAGCTCAGTGATTTCGAGGCCTACCTCAAAGACATGGGCAAAGACTCAGCCTACAAGTTCTCCCTGCAGTTCGAGGAGCTGAAGAGTGTAGGTCTGGATTTGTCCCATGAAGCCGCTGATCTGCCCATCAACAGACCCAAGAACCGCTACACCAACATCCTGCCCTatGACTTCAGTCGAGTGAAGCTGATCTCTCTGCACAATGATGAAGGCTCTGATTACATCAATGCTAACTATATTCCCggctaTAACTCTCCACGCGAGTACATCGCCACGCAGGGCCCACTGCCCGACACCAGGAACGACTTCTGGAAGATGGTGCTGCAGCAGAAAGTGCACATCATCGTGATGCTAACACAGTGCAACGAGCGCCGCAGGGTGAAGTGTGACCACTACTGGCCGTTCAGTGATGAGCCGGTGGCGTATGGAGAGATCAGTGTGGAGATGCTGGCGGAGACAGACTCGCCCGAGTGGACCATCAGGAGCTTCAGACTCGCATACgctgaTGAGACTCAGGACGTCCTGCACTTTAACTACACCTCGTGGCCGGATCACGGAGTGCCGACGGTGAACGCCATCGAGAGCATCCTACAGTTCGTGCAGATCGTCCGGCAGCAGGTCAACAGGAGCAAAGGACCCATCGTAGTgcactgcagtgctGGCGTGGGCCGCACCGGCACCTTCATCTCTCTGGACCGGCTGATGCAGCACATTCAGGAGCACGAGTATGTGGACGTGCTGGGGCTGGTGTCCGACATGCGCTCGCACCGACTGTCCATGGTGCAGACTGAGgagcAGTACGTGTTCATCCATCAGTGTGTTCTGCTGAtgtggaagaagaagaagcagcagTCACACACCAGTGACGTCATCTACGAGAACGTCAGCAAGTCCTAa
>TCONS_00055100
GTGCTGTCATTAGAGATTTTCCAAACACTCCTGATATTGTTGTTggagTGTGGTGCTGAAACTTTCGTCAACTTTGCCTCTTTTGAGCGAGACGGGAAACTGCCGTATAACTGGCGCAGGAGTCTCTTTGCGTTCCTCACGCTTCTGCCATCCTGCCTTTGGACTGACTATCTTTTGGCCTTTTATATTAATCCGTGGAGCAAAACGGCACTTAAGAAGAGGAAACTGACCAGtccgGTACAGCTCAGTGATTTCGAGGCCTACCTCAAAGACATGGGCAAAGACTCAGCCTACAAGTTCTCCCTGCAGTTCGAGGAGCTGAAGAGTGTAGGTCTGGATTTGTCCCATGAAGCCGCTGATCTGCCCATCAACAGACCCAAGAACCGCTACACCAACATCCTGCCCTatGACTTCAGTCGAGTGAAGCTGATCTCTCTGCACAATGATGAAGGCTCTGATTACATCAATGCTAACTATATTCCCggctaTAACTCTCCACGCGAGTACATCGCCACGCAGGGCCCACTGCCCGACACCAGGAACGACTTCTGGAAGATGGTGCTGCAGCAGAAAGTGCACATCATCGTGATGCTAACACAGTGCAACGAGCGCCGCAGGGTGAAGTGTGACCACTACTGGCCGTTCAGTGATGAGCCGGTGGCGTATGGAGAGATCAGTGTGGAGATGCTGGCGGAGACAGACTCGCCCGAGTGGACCATCAGGAGCTTCAGACTCGCATACgctgaTGAGACTCAGGACGTCCTGCACTTTAACTACACCTCGTGGCCGGATCACGGAGTGCCGACGGTGAACGCCATCGAGAGCATCCTACAGTTCGTGCAGATCGTCCGGCAGCAGGTCAACAGGAGCAAAGGACCCATCGTAGTgcactgcagtgctGGCGTGGGCCGCACCGGCACCTTCATCTCTCTGGACCGGCTGATGCAGCACATTCAGGAGCACGAGTATGTGGACGTGCTGGGGCTGGTGTCCGACATGCGCTCGCACCGACTGTCCATGGTGCAGACTGAGgagcAGTACGTGTTCATCCATCAGTGTGTTCTGCTGAtgtggaagaagaagaagcagcagTCACACACCAGTGACGTCATCTACGAGAACGTCAGCAAGTCCTAa

Function

symbol description
ptpro Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within cerebellum morphogenesis and regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; eye; optic cup; optic vesicle; and tail bud. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).

GO:

id name namespace
GO:0021587 cerebellum morphogenesis biological_process
GO:0006470 protein dephosphorylation biological_process
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway biological_process
GO:0007417 central nervous system development biological_process
GO:0016311 dephosphorylation biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016787 hydrolase activity molecular_function
GO:0016791 phosphatase activity molecular_function
GO:0004721 phosphoprotein phosphatase activity molecular_function
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG:

id description
ko01009 Protein phosphatases and associated proteins

ZFIN:

id description
ZDB-GENE-070424-54 Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within cerebellum morphogenesis and regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; eye; optic cup; optic vesicle; and tail bud. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).

Ensembl:

ensembl_id ENSDARG00000110470

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055099 False 1074 mRNA 0.54 10 184863 191736
TCONS_00055098 False 1158 mRNA 0.54 11 184863 191736
TCONS_00055100 True 1137 mRNA 0.54 12 184863 193762

Neighbor

gene id symbol gene type direction distance location
XLOC_028365 eps8a coding downstream 6353 151506 ~ 178510 (-)
XLOC_028364 tbk1 coding downstream 35529 134412 ~ 149334 (-)
XLOC_028363 gpr19 coding downstream 51371 128697 ~ 133492 (-)
XLOC_028361 dusp16 coding downstream 65174 107287 ~ 119689 (-)
XLOC_028362 NA coding downstream 65669 116322 ~ 119194 (-)
XLOC_028368 RERG coding upstream 40050 233812 ~ 240737 (-)
XLOC_028369 si:ch73-252i11.1 coding upstream 75681 269443 ~ 277081 (-)
XLOC_028370 echdc3 coding upstream 92663 286425 ~ 287425 (-)
XLOC_028371 mrps10 coding upstream 131266 325028 ~ 330748 (-)
XLOC_028372 dynlt1 coding upstream 192673 386435 ~ 390442 (-)
XLOC_028360 NA non-coding downstream 83486 99991 ~ 101377 (-)
XLOC_028359 NA non-coding downstream 110255 73430 ~ 74608 (-)
XLOC_028358 NA non-coding downstream 112205 71463 ~ 72658 (-)
XLOC_028357 NA non-coding downstream 120160 56025 ~ 64703 (-)
XLOC_028373 NA non-coding upstream 199789 393551 ~ 396819 (-)
XLOC_028375 CU855889.2 non-coding upstream 507850 701612 ~ 734347 (-)
XLOC_028376 NA non-coding upstream 530068 723830 ~ 732484 (-)
XLOC_028383 NA non-coding upstream 706200 899962 ~ 904022 (-)
XLOC_028385 NA non-coding upstream 725990 919752 ~ 921761 (-)

Expression


Co-expression Network