XLOC_030849 (sh2b3)


Basic Information

Item Value
gene id XLOC_030849
gene name sh2b3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 9556943 ~ 9625459 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00059997
TCACATCTTTTGTGAAAGAATAAGAATATTTGATATATTTCTTATATTCTGTTGCATTCTTTTGTGTTTTAGGACTACAGAATGCCAAAGATTTCCGTACACTGTTCAGACATCAAAGAGATTCGACGCTGTAATCGCCTAGAGATGCCTGATAACATGAACACATTCGTCTTAAAGGTTGCTGGCCTCACGGGTGGTTTTATATTTGAGGCCGATAATGAGCAGCAGGTCAGCTCCTGGACCACTGAGCTCAGAGAATGTATGAGCAGCAGGTCAGATAATGTGGATGGAGAACCATTTCCTGTTAGCGACTCGCTCAGCGCCGCTCGCAGAGGGAGCTCAGATCCTGGAGGCCAGAGCCCGCTAGGTTTTGGACTTGCAGAGCAGGCCTACAATAAAACGCATCACTTCCTGTCTTCTTACTCCTGGTTCCACGGGCCCATCTCTCGTGTGCGAGCGGCTTACCTTGTCCAGCACGCCGGGGTCAGCGGTCATGGGAACTTCCTGGTGAGGCAGAGTGAGACGCGCAGAGGAGATTACGTGCTCACCTTCAACTATCAGGGCCGAGCCAAGCATCTGCGTCTGTCTTTAACTGAATGGGGTCAGTGTCGTGTGCAGCACCTGCGCTTCCCTTCAGTCATGGACATGTTGAGTCACTTCCGCAATTGTCCCATCCCATTGGAGTGCGGAGCCGCCTGTGACGTCATGCTGGCCAATTATGTGCGCGTCAACCCCACACACACAGGTCAGAGCTCGGCTTTTGGCTCTCCTGTGTTGGTGCCTTTCTCACGCTGGAGTTCAGAGCCCAGTTTGGCTCACTGCAGTCCGGATTCGTGTCCTCACTCCAGCTCTTCCATGGCCCAGTCCTGTTCGCCTCCTTCATCGTTAGCCGGACTCTCACACCGCACTCCTTCATTCCTTCCAGACCGTCACGCTCCCCTACACCGCAGCGAGTCTGTGGGCCGCAGAAACCTGCTCCGCCATCCAAACCCACTGCCACCCCTCCTGCCCAACCGGGACTCGGACTACGAACTGGAGCCGCCTGATAGGGGGCGCAAGAGAGCCATCGACAACCAGTATATGTTCTTCTGA
>TCONS_00059998
ATGAATGGTAACACTGTCCAGCAAACCACGAGCACTGCACCATTCGTAGCACCTCCTTGTGGATGGAGGGAGTTCTGCGAGTTGCATGCCAGCACCACGGCCCGAGAACTCGCCCAGCACTACCGGCGCTTCGTCAGAGAGCGGCCGGTGCAGGATGTGGTCCCGCCGGAAAGTTTCTCCAAGCAGTTCAGCGCCCTGTTCCAGCACCACTTCAGCTGTGAGGTGGCCAAAAATGCAGAACTCTCCTTGCGGCCCCCACCGCCACCTCCCTTACTACCTATGACCAGCCGCTTACGCATTACTTCGTTCTCCGGAGTGCTGGATTACAGGGAGACCGTGCGGCCTGCTCCTCTAGTTGCCATATTAGCGCCCAAACCAGATGCTAGTGGCGTTCCTAGGGAACAGGAGCAGTTGCTGCGCTGCTCTCCTCCAGACACTACACACCGTACGCGGAATCACAGTCAGGAAAACGAACGCTCTGATTTTAGGACTGGCTCAGAAGGATACTCTCCCACTGCATGCGACTTCCCTTCCCGAAATGACGTAACTCACATTTCTGTCAGTCGCATTCGAGAAAGCGTTTGTCGACTTTTTAAGAAATCACCGCAATTTGGCGAATCCTCAAGTTGTTGTCCAAGGGACGAGTTGATCCCGAGTGGTGGACCACCTGTGAGTGTTGAATGCACCCCTCACAGCCCACCTGTGCAGGTACCCACCAATCGCACTTCACAGAGGGCTGCACTGTGGGAGCGCTGGAATCCATGGCGGACTGTGAGACGGAGGCAAGAGTTTGGAAGTGTTTGTAAAGAGGGGCAGCTGCGGTACCTAGAGGTGGACGACACTATTTCAGACACGGCCCCACAATGGCAGCGCTGCCGCCTGCAGGTCAGGAGGACCAATGAGCACAGCGCTAGCCAGAGGTACCTGCTAGAGCTCTACGACCCACCCAAGGACTACAGAATGCCAAAGATTTCCGTACACTGTTCAGACATCAAAGAGATTCGACGCTGTAATCGCCTAGAGATGCCTGATAACATGAACACATTCGTCTTAAAGGTTGCTGGCCTCACGGGTGGTTTTATATTTGAGGCCGATAATGAGCAGCAGGTCAGCTCCTGGACCACTGAGCTCAGAGAATGTATGAGCAGCAGGTCAGATAATGTGGATGGAGAACCATTTCCTGTTAGCGACTCGCTCAGCGCCGCTCGCAGAGGGAGCTCAGATCCTGGAGGCCAGAGCCCGCTAGGTTTTGGACTTGCAGAGCAGGCCTACAATAAAACGCATCACTTCCTGTCTTCTTACTCCTGGTTCCACGGGCCCATCTCTCGTGTGCGAGCGGCTTACCTTGTCCAGCACGCCGGGGTCAGCGGTCATGGGAACTTCCTGGTGAGGCAGAGTGAGACGCGCAGAGGAGATTACGTGCTCACCTTCAACTATCAGGGCCGAGCCAAGCATCTGCGTCTGTCTTTAACTGAATGGGGTCAGTGTCGTGTGCAGCACCTGCGCTTCCCTTCAGTCATGGACATGTTGAGTCACTTCCGCAATTGTCCCATCCCATTGGAGTGCGGAGCCGCCTGTGACGTCATGCTGGCCAATTATGTGCGCGTCAACCCCACACACACAGACCGTCACGCTCCCCTACACCGCAGCGAGTCTGTGGGCCGCAGAAACCTGCTCCGCCATCCAAACCCACTGCCACCCCTCCTGCCCAACCGGGACTCGGACTACGAACTGGAGCCGCCTGATAGGGGGCGCAAGAGAGCCATCGACAACCAGTATATGTTCTTCTGA

Function

symbol description
sh2b3 Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within hemopoiesis and signal transduction. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in essential thrombocythemia; familial erythrocytosis 1; and myelofibrosis. Orthologous to human SH2B3 (SH2B adaptor protein 3).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity molecular_function
GO:0035591 signaling adaptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041210-359 Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within hemopoiesis and signal transduction. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in essential thrombocythemia; familial erythrocytosis 1; and myelofibrosis. Orthologous to human SH2B3 (SH2B adaptor protein 3).

Ensembl:

ensembl_id ENSDARG00000069958

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00059997 False 1092 mRNA 0.54 6 9556943 9580837
TCONS_00059998 True 1791 mRNA 0.56 7 9556943 9625459

Neighbor

gene id symbol gene type direction distance location
XLOC_030848 gak coding downstream 16173 9441198 ~ 9540770 (-)
XLOC_030847 lrp13 coding downstream 340185 9179578 ~ 9216758 (-)
XLOC_030846 AL845369.2 coding downstream 377507 9173538 ~ 9179436 (-)
XLOC_030845 AL845369.1 coding downstream 386409 9166395 ~ 9170534 (-)
XLOC_030844 NA coding downstream 410166 9144367 ~ 9146777 (-)
XLOC_030850 si:ch211-193c2.2 coding upstream 51846 9677305 ~ 9678075 (-)
XLOC_030851 ddr2l coding upstream 74463 9699922 ~ 9793273 (-)
XLOC_030852 zgc:158343 coding upstream 198295 9823754 ~ 9824908 (-)
XLOC_030853 NA coding upstream 254729 9880188 ~ 9882404 (-)
XLOC_030854 tor4ab coding upstream 268684 9894143 ~ 9948497 (-)
XLOC_030843 NA non-coding downstream 429384 9107085 ~ 9127559 (-)
XLOC_030840 NA non-coding downstream 525192 9030240 ~ 9031751 (-)
XLOC_030859 NA non-coding upstream 590055 10215514 ~ 10217606 (-)
XLOC_030861 NA non-coding upstream 863478 10488937 ~ 10500797 (-)
XLOC_030862 BX511089.3 non-coding upstream 882367 10507826 ~ 10508814 (-)
XLOC_030863 CR790366.3 non-coding upstream 1095435 10720894 ~ 10724665 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000338_00506580_00532078 SH2B3 coding CI01000338 null 506580 ~ 532221 (-)
rainbow trout (Oncorhynchus mykiss) G474537 LOC106585852 non-coding NC_048570.1 CM023224.2 11909197 ~ 11910150 (-)