| Item | Value |
|---|---|
| gene id | XLOC_030879 |
| gene name | nos1 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007116.7 |
| NCBI id | CM002889.2 |
| chromosome length | 72500376 |
| location | 12100126 ~ 12525441 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| nos1 | Predicted to enable FMN binding activity; flavin adenine dinucleotide binding activity; and nitric-oxide synthase activity. Acts upstream of or within several processes, including animal organ development; collateral sprouting; and nitric oxide mediated signal transduction. Predicted to be located in dendritic spine and sarcolemma. Predicted to be active in several cellular components, including cytosol; postsynaptic density; and vesicle membrane. Is expressed in brain; enteric nervous system; nitrergic neurons; spinal cord; and trunk. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1). |
| id | name | namespace |
|---|---|---|
| GO:0007210 | serotonin receptor signaling pathway | biological_process |
| GO:0006936 | muscle contraction | biological_process |
| GO:0031284 | positive regulation of guanylate cyclase activity | biological_process |
| GO:0045776 | negative regulation of blood pressure | biological_process |
| GO:0007263 | nitric oxide mediated signal transduction | biological_process |
| GO:0098924 | retrograde trans-synaptic signaling by nitric oxide | biological_process |
| GO:0060218 | hematopoietic stem cell differentiation | biological_process |
| GO:0055114 | oxidation-reduction process | biological_process |
| GO:0001889 | liver development | biological_process |
| GO:0006527 | arginine catabolic process | biological_process |
| GO:0009725 | response to hormone | biological_process |
| GO:0048668 | collateral sprouting | biological_process |
| GO:0032496 | response to lipopolysaccharide | biological_process |
| GO:0006809 | nitric oxide biosynthetic process | biological_process |
| GO:0021517 | ventral spinal cord development | biological_process |
| GO:0005829 | cytosol | cellular_component |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0012506 | vesicle membrane | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0014069 | postsynaptic density | cellular_component |
| GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | molecular_function |
| GO:0005516 | calmodulin binding | molecular_function |
| GO:0004517 | nitric-oxide synthase activity | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0003958 | NADPH-hemoprotein reductase activity | molecular_function |
| GO:0016491 | oxidoreductase activity | molecular_function |
| GO:0050660 | flavin adenine dinucleotide binding | molecular_function |
| GO:0050661 | NADP binding | molecular_function |
| GO:0010181 | FMN binding | molecular_function |
| GO:0020037 | heme binding | molecular_function |
| id | description |
|---|---|
| ko00220 | Arginine biosynthesis |
| ko00330 | Arginine and proline metabolism |
| ko04371 | Apelin signaling pathway |
| ko04020 | Calcium signaling pathway |
| ko04145 | Phagosome |
| ko04926 | Relaxin signaling pathway |
| ko04970 | Salivary secretion |
| ko04730 | Long-term depression |
| ko04713 | Circadian entrainment |
| ko05010 | Alzheimer disease |
| ko05014 | Amyotrophic lateral sclerosis |
| ko05022 | Pathways of neurodegeneration - multiple diseases |
| ko03019 | Messenger RNA biogenesis |
| id | description |
|---|---|
| ZDB-GENE-001101-1 | Predicted to enable FMN binding activity; flavin adenine dinucleotide binding activity; and nitric-oxide synthase activity. Acts upstream of or within several processes, including animal organ development; collateral sprouting; and nitric oxide mediated signal transduction. Predicted to be located in dendritic spine and sarcolemma. Predicted to be active in several cellular components, including cytosol; postsynaptic density; and vesicle membrane. Is expressed in brain; enteric nervous system; nitrergic neurons; spinal cord; and trunk. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; asthma; cystic fibrosis; and hypertrophic pyloric stenosis. Orthologous to human NOS1 (nitric oxide synthase 1). |
| ZDB-GENE-030131-8047 | Predicted to enable protein kinase activity. Predicted to be involved in Ras protein signal transduction and calcium-mediated signaling. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human KSR2 (kinase suppressor of ras 2). |
| ensembl_id | ENSDARG00000068910 ENSDARG00000094172 ENSDARG00000094526 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00060036 | False | 4851 | mRNA | 0.49 | 28 | 12100126 | 12219572 |
| TCONS_00060037 | False | 4608 | mRNA | 0.50 | 29 | 12100669 | 12223434 |
| TCONS_00060038 | False | 4864 | mRNA | 0.49 | 29 | 12100669 | 12272689 |
| TCONS_00061955 | False | 7803 | lncRNA | 0.32 | 1 | 12272137 | 12279939 |
| TCONS_00060040 | False | 729 | lncRNA | 0.41 | 2 | 12272137 | 12280127 |
| TCONS_00060041 | False | 3479 | mRNA | 0.52 | 22 | 12272632 | 12525441 |
| TCONS_00060042 | False | 6141 | mRNA | 0.45 | 21 | 12283097 | 12525441 |
| TCONS_00060043 | False | 1873 | mRNA | 0.52 | 15 | 12285726 | 12407194 |
| TCONS_00060044 | False | 465 | processed_transcript | 0.50 | 3 | 12353721 | 12372897 |
| TCONS_00060046 | True | 469 | mRNA | 0.46 | 2 | 12503494 | 12524996 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_030878 | lrrc74b | coding | downstream | 6508 | 12065957 ~ 12093618 (-) |
| XLOC_030877 | nipsnap1 | coding | downstream | 36745 | 12032802 ~ 12063381 (-) |
| XLOC_030876 | castor1 | coding | downstream | 68205 | 11982364 ~ 12031921 (-) |
| XLOC_030875 | osm | coding | downstream | 128180 | 11965113 ~ 11971946 (-) |
| XLOC_030874 | rnft2 | coding | downstream | 155728 | 11916928 ~ 11944398 (-) |
| XLOC_030882 | wsb2 | coding | upstream | 24110 | 12549551 ~ 12560569 (-) |
| XLOC_030883 | vsig10 | coding | upstream | 36747 | 12562188 ~ 12587053 (-) |
| XLOC_030884 | aifm3 | coding | upstream | 112382 | 12637823 ~ 12701603 (-) |
| XLOC_030885 | si:dkey-98f17.3 | coding | upstream | 187817 | 12713258 ~ 12713920 (-) |
| XLOC_030886 | lztr1 | coding | upstream | 198605 | 12724046 ~ 12743212 (-) |
| XLOC_030871 | NA | non-coding | downstream | 436798 | 11576673 ~ 11663328 (-) |
| XLOC_030869 | NA | non-coding | downstream | 633973 | 11356637 ~ 11466153 (-) |
| XLOC_030868 | CABZ01077121.1 | non-coding | downstream | 816605 | 11278426 ~ 11283521 (-) |
| XLOC_030866 | NA | non-coding | downstream | 1061821 | 11037177 ~ 11038305 (-) |
| XLOC_030888 | NA | non-coding | upstream | 310085 | 12835526 ~ 12836607 (-) |
| XLOC_030893 | NA | non-coding | upstream | 751800 | 13277241 ~ 13306705 (-) |
| XLOC_030896 | AL954191.1 | non-coding | upstream | 1007433 | 13532874 ~ 13532988 (-) |
| XLOC_030905 | CR388049.1 | non-coding | upstream | 1719708 | 14245149 ~ 14245280 (-) |
| XLOC_030911 | NA | non-coding | upstream | 2255401 | 14780842 ~ 15176098 (-) |
| species | gene id | symbol | gene type | chromosome | NCBI id | location |
|---|---|---|---|---|---|---|
| grasscarp (Ctenopharyngodon idella) | CI01000071_04851502_04865548 | KSR2 | coding | CI01000071 | null | 4851502 ~ 4865548 (+) |