XLOC_003323 (rtel1)


Basic Information

Item Value
gene id XLOC_003323
gene name rtel1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 12811906 ~ 12859263 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006503
GATTGTTGAAAGTTTAGTGCATCGTTTACCGTTGTGTCATGTTTTAAAGAAAGAGCTAATTAATTCGAATGATTGTTTATTCGTGCTTTTTTAAGGGGCTGTGGTTTAGCGTTGAGAGTGGGTGATTTAGCGTTACTTTTTCAGATGTTGTCAGTGTGTTTTGGTAGAAAATGCCTGTTATTAAACTTAAAGGAATCAATGTGGACTTTCCCTTCACCCCGTACCCCTGCCAGGAGGACTACATGAGCAAAGTCATCGAGTGCCTGCAGAAAAAAGTCAATGGTGTCCTTGAAAGTCCCACTGGCACAGGTAAAACGCTCTGTCTTCTGTGTTCGACGCTGGCATGGAGAGACCACTTCAAAGACACCATCTCTGCCCGCAAGATAACAGAGAGAATGGGTGGAGCTGAGCTGTTTGCAGATAGACCAATGTCATCATGGGGAACAGCAGCTACTGATGGAGACACACCAActTATTATACTGACATTCCCAAGATCATATATGCCTCCAGGACTCATTCGCAGTTAACACAAGTTGTAAATGAGCTGAAGAATACATCATACAGGCCAAAGATTTGTGTTTTGGGATCTAGAGAGCAGCTCTGCATAAACCAGGAAGTGATGCGTCATGAAAGTAATCACATTAAGGTCCACATGTGCAGAGCAAAAGTCTCGTCCCGTTCCTGTATCTTCTACAACAATGTCGATGAGAAAAGCACTGACAAGGAGATTGTGAATTCTATTCTGGATGTGGAGGATCTTGTAAAAACAGGCAAAAAGCAAAGAGTTTGTCCATATTACCTGTCACGCTCACTCAAACAACACGCTGATGTCATCTTCATGCCCTACAACTACCTGCTTGACCCAAAGAGTCGAAGAGCACACAATATAGAGCTGAAAGGGGCTGTGGTTATTTTTGACGAAGCTCATAATGTCgagaaGATGTGTGAAGAGTCCACCTCGTTTGACCTCACGCCTCATGACCTGATTTCTGCCATCGAGGCCGTGGATCGACTTCTGCGAGAGCAGGCCTCAGACATCAGCAAAGCAGATTCTGCTGAAGACTTTAATGTGGAATCACTCAATTCAGGTTTGAAAATGGACATCACCACAATTGCAAAAGTAAAACAAATTTTGATGGATCTGGAAACTGCCATTAATGATTTTGAGATGCCAGCAAACAATCAAGGAATCACCAAACCTGGCAGCTTCATATTTGAGCTTTTTGAAATGGCTAATGTGAACTCTAAAACTAAAACAGAAACTGTTGAAGCCATGGAGCAGATCACAGGCTATTTAGCTGGCAGACCTGGTGTCTTTTTGAACACTAGTGGACTTCAGAAAGTGGCAGATATTATCCAGTTGGTGTTTGTGGCTGAACCTGCAGAGGGCAGCAAGAAATCACAGACTGGAAATAGTTTAAAGGAGTTCAAGGTCCACATTCATCCAGACAACAGCAACTTCAAGAAGAAGCAGATCACGGATGTTTGGGCTTCCTCTTCGACTAAGAAACAAGGGAACGTGCTGAGCTACTGGTGTTTTTCTCCGGGCTTCAGCATGCAGGAGTTGCTCCGTCAGGAAGTTCGCTGCATTATTCTGACCAGCGGAACCCTCTCGCCCCTCTCATCCTTCACCTGTGAAATGCAAATTCCTTTCCCCGTATCCCTGGAGAACCCTCATGTCATCCAGCGTGATCAGATCTTCGTCAGTATCATTGAAAAAGGTCCAGATGGAGTTCAGCTGAGCACGGCTTTTGACAGGAGGTTTGTTCCTGAAAACATGTCGTCCATGGGAAACACTCTCgTAAATCTGTCACGGGTGGTCCCTCATGGGctgctagtgtttttcccatcaTACCCAGTCATGGATAAAACTCTGGAGTTCTGgaggGCAAAAGGACATGCAGATCGCATTGAAAATGTGAAACCCATGTTTGTAGAGCCGAGGGGTAAAGGCACTTTTACAGAGgTGATTGATGGCTATTATGGCAAGGTGGATGACCCAAACTCTAGTGGAGGCAGCTTTTTTGCTGTGTGTAGAGGAAAGGCAAGTGAAGGATTGGACTTTGCTGACACATACGGTCGAGGGGTTGTTATCACTGGACTTCCCTTTCCCCCCAGGATGGACCCCAGAGTGGTGCTAAAAATGCAGTATCTGGATGAAATGTGCAGGAATAAAATTAGTGGAGTAAAGTATTTAACTGGCCAGGAATGGTACAGACAGCAGGCCTCTCGAGCTGTGAATCAAGCCATTGGCAGAGTGATCCGCCACAGAGAAGACTATGGAGCCATCTTTCTCTGTGATCACAGGTTCAAAAGCGCAGACGCCCGTAATCAGCTTCCTTCCTGGGTGAGGCCCTATGTTAAGATTTATGATGGCTTTGGTACTATGGTCCGTGATGTGGCTCAATTTTTTCGAACAGCGCAAAAAACTAGACCGGTTCCTGTTAAGAAAGGAAAGGCTGAGGGCCATGAAAATCAGGCAGACACCAGACTGCTCAACACAGGCTCCAGCTGCCTTACTAAGAGTGTCTGGCCCAGTGACATCTATCAAAAGGCCAAAACACTAGACGCTCACGTCCCCAGCCTAAAAAGAAGAAAATTAGACTCCGAAGAGCATTCAGGACGAGAAGGTGCAGCCAGACTTTGCATTCAATATGAGATGGAGATGACAAGCAAAAGGAAACCAGTCAGCCTGCTGGATGCCCTGGATGACACAACCGACAAAGAAGAAAGGGAAGACACCATGGTTGGGGAGGAAAGAGCGAGTCACTTGTCTACTCTTTCTCTCCAGCATGACAAACGTCTGGATGATGAATCGAGGGGCGGGAAACGGAAAATTAAAGTGGTTCAAGAACGGGAAACAGTGACTTCCCATACTGCAAAAACTGGCAAGGCTTTCATGATGGAGCTGAGAAGATGCCTGAGTCATGAGAACTTCAAGCTAATCATGGAGGCGCTTCAGTCATACAAGACGGCAGATAACTTGAATAACCTTCTGGCTACTGTGGCTGAACCCCTCATACAAGACCACAACACTCACAGTCTGCTGAGAGGTCTTTATCAGTTTATCCGACCACACCATAAGAAAGAATATGATGAGCGTTGTTTGGAGTTAACAGGTGAAGGTTGTGGCTACAAACAGGAGCATTCATTGTCCAGAGAGGAAAAAGAAGCTCTCAGGCACAACTCAGTGAAAGCTGAGATTCCTCCTGTAAATCCACCCATTGAGCAGCTGAATTCTAGTCGACTGCTGAACCAAGGTGGTTCGCACCTAGGAACCATCCAACTTAATGGAGGGGAAGTGAATGTGAGAAGTGAAGAGCAGAAGCCACAAACATCCATCAAAGAAGGCCCGTCGTGCTCTTCTCTGCTGTCAGACATAAAACAGGCCATCGGTGCAGAAAAAACCCGTCAGATGTTTTCAGCCTTGCAGGCGTATAAAACGTCAAACAATTATGAACAGATGGTTTCAACTGTTGTGAGCTTATTGACCGAGAGAGATGAAGACATCGCTCTACTAGAACGTTTATCTGTGCTCATTCGACCACAGCACAGGAAGCAGTTTGGTGAGCTGTTAAAATCCTTGACTGGAAATGATTCTGCGGTTGTCCAGGATTCAGACATTGGATCAAGTCAGTTAAATcaagcAACTCAGTTATCTGGAGGAAAGACTCAACGCAAGATATCGTCCTTCTTTTCATGAATGCTGCTAGGTTTTGAGATATTAAATCAGTATCTTCTTGTTATTTACATATACCATGCATACAGGGCTTTATGCAGGAGAGTGTTAAAAACTTATATTGCACATCTGACATATTACAATGcattaaatgtatttacaattttttggTTTATACTTaagatcattttttaaaaataaataaatgaattagttttatactttacatttaaattgtgttttttaaattcttttgaaaaaaaaaagtcattttaataaaGGATATTGTGAGTGA

Function

symbol description
rtel1 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; ATP binding activity; and DNA helicase activity. Predicted to be involved in regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA metabolic process and DNA replication. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 5. Orthologous to human RTEL1 (regulator of telomere elongation helicase 1).

GO:

id name namespace
GO:0006310 DNA recombination biological_process
GO:0006974 cellular response to DNA damage stimulus biological_process
GO:0006139 nucleobase-containing compound metabolic process biological_process
GO:0000723 telomere maintenance biological_process
GO:0006260 DNA replication biological_process
GO:0010569 regulation of double-strand break repair via homologous recombination biological_process
GO:0006281 DNA repair biological_process
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003678 DNA helicase activity molecular_function
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides molecular_function
GO:0051536 iron-sulfur cluster binding molecular_function
GO:0051539 4 iron, 4 sulfur cluster binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004386 helicase activity molecular_function

KEGG:

id description
ko03032 DNA replication proteins

ZFIN:

id description
ZDB-GENE-050306-11 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; ATP binding activity; and DNA helicase activity. Predicted to be involved in regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA metabolic process and DNA replication. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 5. Orthologous to human RTEL1 (regulator of telomere elongation helicase 1).

Ensembl:

ensembl_id ENSDARG00000035074

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006503 True 3975 mRNA 0.44 33 12811906 12859263

Neighbor

gene id symbol gene type direction distance location
XLOC_003322 NA coding upstream 26847 12782215 ~ 12785059 (+)
XLOC_003321 rbb4l coding upstream 41360 12744575 ~ 12770546 (+)
XLOC_003320 ap1s2 coding upstream 83553 12719944 ~ 12728353 (+)
XLOC_003319 NA coding upstream 93504 12718109 ~ 12718402 (+)
XLOC_003307 NA coding upstream 288877 12522770 ~ 12523029 (+)
XLOC_003324 zgpat coding downstream 997 12860260 ~ 12875188 (+)
XLOC_003325 si:dkey-11m19.5 coding downstream 20372 12879635 ~ 12955738 (+)
XLOC_003326 btf3l4 coding downstream 164739 13024002 ~ 13055807 (+)
XLOC_003327 ptgfr coding downstream 173220 13032483 ~ 13038233 (+)
XLOC_003328 zfyve9b coding downstream 199350 13058613 ~ 13088179 (+)
XLOC_003318 CR450764.6 misc upstream 99910 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 117643 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 126307 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 131878 12679732 ~ 12680028 (+)
XLOC_003314 CR450764.9 misc upstream 188055 12623555 ~ 12623851 (+)
XLOC_003369 CR854846.2 misc downstream 3263523 16122786 ~ 16123082 (+)
XLOC_003304 NA non-coding upstream 317729 12493872 ~ 12494177 (+)
XLOC_003302 NA non-coding upstream 344846 12466766 ~ 12467060 (+)
XLOC_003329 CR847923.1 non-coding downstream 292656 13151919 ~ 13152385 (+)
XLOC_003332 NA non-coding downstream 334460 13193723 ~ 13194597 (+)
XLOC_003341 CR555295.2 non-coding downstream 958306 13817569 ~ 13817684 (+)
XLOC_003342 AL928649.1 non-coding downstream 1005583 13864846 ~ 13864964 (+)
XLOC_003344 CT956066.1 non-coding downstream 1222277 14081540 ~ 14082177 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000305_00415773_00440799 RTEL1 coding CI01000305 null 414514 ~ 440799 (+)