XLOC_037543 (en1a)


Basic Information

Item Value
gene id XLOC_037543
gene name en1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 778745 ~ 785444 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073767
GCTTTTATTAACCAACGTCATGCTGCTGTTACAGAAAATGCTCagaatgctcatttttttgtttgtttgtctgtctgtttgttttccCCAAAAGCGTCGCTTTAGACACCTGCAGGCCTGTGTTCGGTGTGATTTTATTAACTCTCGGCTCTAGACAGGGCTGGACTGATCTCTGTGCAGGTTGATGTATAGCCTGTCAGTGCGCACTGCGGGCGCGGAACGGAATTGGACGCGGACACACGTGGCACGGAGCTCCTTTGTCATGGATAGGCTCCCAACTCATCCGAGTGATCTGATGTGTTTCCGGCTGGAGGCCACTAAGAGTGGTTGTGCACGAGTAGACTTCCAGAaagaaagggggaaaaaaaagagaaaagaaagaggTGTCAAGCTTTACGCATGAGAGCTCTGTATCGCGCTCTCTCCAAAGACGCGCGCGTAGTTATATTAACAGAATCTCCACAGCATGCCAACAAGTTGACTTACCAAAATAATGAGCTCGCGAGTAATTAGCGCGTTGTCATGGAAACCTAGATAACATTCTCACGTCTTAATAGTTATATTTGGAACAGAACAACGGGATAAATCCAGGAGGGGAGCTGTTATGGAGGATCAGCGGCGGGGTCAGGGTGAGGAGGAGGATGACAGCGGATCTCTGCCCTCTCCACCTTTGCTCCCTGCGCACAGAAACACTGATTTCTTCATCGATAACATCCTCAGACCGGACTTCGGTTGtaaaagagagcgagagagagtaACGCGGGATTCGGGTGTCCGACCGACTGCTGTCCTGGACTCCCGGAGCGACGGTGTTTCTTCTTCGGCCTCGTCCACCGTTTCATCTCCGGTTTCCAGCAGTCAGTCTAATAAGGTGGAGCAGGGATCCAGTAAATCCTCCTCGCCCAGTAAAGACAGCCAGAAGCAGATTTTGTGGCCCGCTTGGGTTTATTGCACGAGATACTCTGATCGGCCTTCATCTGGCCCAAGGACCCGGAAATTGAAAAAGAAGAATAACAATACCGAAAGCGACGATAAGCGACCCAGAACGGCGTTCACAGCCGAGCAGCTCCAGAGACTGAAGGCAGAGTTTCAGACTAGCCGCTACATCACGGAGCAGAGGCGGCAGGCTTTAGCGCGGGAACTCGGCCTCAACGAGTCGCAGATCAAAATATGGTTCCAGAATAAGCGCGCCAAAATCAAGAAGTCCAGCGGCTTCAAAAACGCGCTCGCAATGCAGCTAATGGCGCAGGGATTGTACAACCATTCCACCACCACCATCCAAGAAGAGGAGGACAACTAGCAGAGACAAATCCTGGAGTGAAATTAATCACAAGACTTTAAAACAGATATTATAGCCTATGTTTACTGAGCGGGAGATGTATTGTAGTGTAAACAAAATCTGTACATTAGCAGCTTTCtgcattttgtgattcattttgtATTCTTCCCTTGtattaatgcttttgaattgcattatggcagcttgatctttcttccaacaacttttaatcttgaaaagctcgcaaagtgacttttattaacagttttaatattttatattgtctAAGTTGGTGTTGTAGCCTATATTACGATACAAAAAcgttgtaataaactgcagcacatattctgttattttacagacttgtttCTCTTTATATTATTCCTTACACATTCTATTATTTCAAActagtaaaatgtaaataaggtGACTTTTAAAGTCGACAGAGAGAGCAGATATCAACATCACCTAATGCAATTCACCAGCGCAAATAAACGGAAAActcttgtaaatcacaaaatgagctgttaattaaaatattattttaaagtgtatacAAAACTGAAATTAAACTGACAGCCTCTTTATTTTAAAGATGCGAATAAAGTTTAATATGGTTTGTTATTCAGTTATAATTTACTTCAACTATGATGTTTTATATAAGCTGTTAACTGCAGTATATGCCAAAGACGCTATTCGATTGAATTTATAAAATTAGCAGCTATAATGTTTTAAACTGTATATCCATAATATTTTCCCTTTGCTGGTGGTATACTTGGGATAATGGGAAATAAAGATGTGATTTCAGATAGTATTcttcataatatatttaatactCTATTCAAATAAACTCATTTTGTACATGAAATACGAGGCGTGTTGTCTTATTATGTTGTCTTCTGTATAggtagattattatttattttatcctgGGGCAGGAATAAGTGAACCAaccaaaatgttaaaaaataatacgataataataaatgtttccccAATATATTCACTCATGTTTCGTAGAATAAAGCCACTTTAACATAATTTTTTGCTTTTTACGCGACAAACTGCGGCCTTATTTTGTCTTTGTAATgaagataaaacaaaatataacatCTCCGTGTGATAATTTCCCATTTAAAACTTTAATGCGACTCATAATACCTGTAAAAATGCTTGGTTCGAAACAAgcgatttgtttttaattatcttatttacacatttaattataattaatataaaacagttaagttgtcccccGAAAACTCAATATGTGTGTTGTTTTGGCTCATTGTAAATAAGCGGTTTAAACAAACATCAAACGTCACTTTTAAATGTAGATTAATTCGCATAAACGACTTTCAGATCAATCAATAATCAGAATGATTTAAACTGCATGTACACCGTGTTGTTGTAGAAATGCTAAAGCATGGAAAATACCTTATTATCTGCAagacttttttaattttaatagcaataataattaacaatactGTGTTATTTGTTTGGGAGAATGCGGCTTTTTTAAAACCACATCATATTTAGCATTCCACTGAGAGTTTGAGAACAGTAGTCTAGTGAATGTCGGCTGTTGTGAGCATGCCATAGCTTTTTGTAAGCGATTAATCAAACCAAAGAAGACAGATAATCGTGGACACATTATCCCGATGGCAGGCACTGTTTGTTTTCTGAAGCTCTCTGCCCCGGGCAACATTTAACAGATCTGCATTGGACATCCAGCATGATTGTGTGGCTGCATATATCCGTGGTTTTCTCACACCTTCACTATCATCTCGgtatggcgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgcgcgcgcgcttGTGAATGTGTCCGGGCAGGCTCGGCTGACTGACTGCTGGAATTAGCGACTGTCAAGTTCAAAAGCGAGTTACACTTGATTGAGATCTTGGCCTGTTTTTGTCAACTTCTTAAAACCACATAAATAGAGCCTTCAAATTGTGATTGAAAAAGTATAATAGCGGGTTCCCGTAGCTATCAGCGGAAATTTCCACACGGTAAAAACACATCTGTTAATGCACAAGTGGTTATTTGCCGTGGTGAATTGCATTaggggatgttgatctctgctctgtccactttttaTGTTGGAATaacaactctacagtttaacaaagtgacttttattgacgttttagtagttaaaaataacatatacgaaataaagtataaaaataagtgTGTAAATTAACAAAATGTATTGCCAGTTTATTACAATGTctctgtagtgtaatatacaacactaaCCTATTTGAATAGCACTGCTAActattaaaaatactaattaaagtcacttttttcaaacttttcaagggtAAAACTTCAAGGTGTCAACTTAAAAGCAGAAATAATCCGGTGAAGAATAAAAACACaatacggaaaactgctaatttacggatattttagTGCCTGGCATGTTTACTCTCTCATTCATTATCCTGATTTTTCAGAggatgccacagcggaacgaaccgccgaTAACTTTGGCATGTGTTTTATGCGGCGGGTGCCATTCCAGTGCATGCCTGAAATAGCCTCATTTATTTGAGGAAACCACCAAACTTTTCGGTTTGGCTATCCAAAACCTGCATCTCAGATATACTGACGGATACGGATATACTGATAAATAAAATCAGTGTCAAATAAGGAGTTATTGAGGGGAAAGAAGTTTGTATTCAAACACAAAAACCGTATTTTAAAATCACACCAGGTTGTTTCAACCAAGTTTTGGGCCAAATATGAAGAAACCTGAGGTTGGATAGTTCTTTTCCCAATTGCATTACAATTGCACTTTTAAACCGGCTCGTTTGTTCATATTTAAGCGAGCTTTGAGTTCCAACACGccaacatttttagagtgtaaatgGACGAAAGTATAGCACATAGAAATTTCTATTAGTAAAACAGAATGAACACGTGGAAACAATTGAAGTTACTGGGGGAAAAGGCTTTCACAATATCTGAATCAAACGACCAATAAaagtttgtatatatttttttaaaaataaacagtttcTGGAAAAATATGTATGAACTTGTTATAAGTATATATAT

Function

symbol description
en1a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis involved in innervation. Predicted to be active in nucleus. Is expressed in several structures, including adaxial cell; midbrain hindbrain boundary neural rod; musculature system; pectoral fin bud; and somite. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human EN1 (engrailed homeobox 1).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0060385 axonogenesis involved in innervation biological_process
GO:0030182 neuron differentiation biological_process
GO:0007275 multicellular organism development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-216 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis involved in innervation. Predicted to be active in nucleus. Is expressed in several structures, including adaxial cell; midbrain hindbrain boundary neural rod; musculature system; pectoral fin bud; and somite. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human EN1 (engrailed homeobox 1).

Ensembl:

ensembl_id ENSDARG00000014321

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073767 True 4451 mRNA 0.39 2 778745 785444

Neighbor

gene id symbol gene type direction distance location
XLOC_037542 NA coding downstream 5089 772863 ~ 773656 (-)
XLOC_037541 NA coding downstream 20329 757593 ~ 758416 (-)
XLOC_037540 ndufb3 coding downstream 32428 707086 ~ 746317 (-)
XLOC_037539 cflarb coding downstream 74078 701452 ~ 704667 (-)
XLOC_037538 dip2a coding downstream 83745 584940 ~ 695000 (-)
XLOC_037544 marco coding upstream 10165 795609 ~ 813693 (-)
XLOC_037545 c1ql2 coding upstream 58777 844221 ~ 849069 (-)
XLOC_037546 NA coding upstream 95304 880748 ~ 889567 (-)
XLOC_037547 C9H2orf76 coding upstream 114948 900392 ~ 904227 (-)
XLOC_037548 sctr coding upstream 140525 925969 ~ 950004 (-)
XLOC_037533 NA non-coding downstream 340942 434375 ~ 437803 (-)
XLOC_037532 CR753874.2 non-coding downstream 364257 407678 ~ 414488 (-)
XLOC_037520 NA non-coding downstream 529312 228667 ~ 249433 (-)
XLOC_037549 CABZ01066922.1 non-coding upstream 217997 1003441 ~ 1003555 (-)
XLOC_037550 NA non-coding upstream 241571 1027015 ~ 1028650 (-)
XLOC_037551 NA non-coding upstream 392457 1177901 ~ 1181454 (-)
XLOC_037554 NA non-coding upstream 517493 1302937 ~ 1305423 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000353_01217647_01220529 NA coding CI01000353 null 1217174 ~ 1221247 (-)