XLOC_000395 (chmp2bb)


Basic Information

Item Value
gene id XLOC_000395
gene name chmp2bb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 33558555 ~ 33569245 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000676
GAAGAGCAGAAGTTCACCGCCTTCTTGTCAGGAACCAGGAAATAGTCATGATATTTTGATAGCCAACTCTCACTTGATAATAGTCATTGTGATATACTTAGTTTTCTTATTAGTTTCTTGGTCGGCGGAGTTTGTTGCAGTTATGACATCGTTATTCAAGAAAAAGACCGTAGATGATGTCAttaaagaacaaaacaaagaGCTGCGAGGAACGCAGAGACAAATTGCCAGAGACCGGACAGCACTGGAAAAACAGGAAAAGCAACTGGAGATGGAAATCAAGAAAATGGCAAAAACAGGGAACAGAGACGCCTGCAAAGTTTTAGCCAAGCAACTTGTGCAAGTGAGAAAACAGAAGACGCGCACATATGCAGTCAGCTCAAAGGTCACCTCCATGTCCACACAAACCAAACTTATGAACTCCCAGATGAAGATGGCTGGTGCTATGGCCACAACTACAAAAACAATGCAAGCTGTCAACAAAAAGATGGATCCAAAGAAGACCATGCAGACCCTGCAGAACTTCCAGAAAGAAACCGCAAAGATGGACATGACAGAGGAGATGATGAACGACACCCTGGATGAGATCTTCGAGGATTCTGGAGATGAGGAAGAATCTCAGGACATTGTGAACCAGGTGTTGGATGAAATTGGAATTGAGATCTCAGGAAAGATGGCTCATGCTCCTTCAGCTGCGCGAAAAACCCCAAGCGCCGCCACGGCCAAAGCAGATGGGATCTCAGATGAGGATATCGAGAGGCAGCTCAAAGCCCTTGGAGTGGACTAGTgctcatgcactcacacacacacatacacaaacaaacacctgATCATTGCCTGGCAACAGAAGGCAACccaaacacacactaaaacacattcataccaaataacaaatacacaaacaaacagtcCAAAAGCTCACATTCACACTTGCCTACTCTGGGATACCGCACCACAGATGACAAATGCAATTTTTTGTTCCTATTTATTTATGACAATGAGAGATGGCTGTCAAGGGTGTTTAAGACTCTTTCAGGTGAACCGCTATTGCTTTTAGAAGGATAAAAATAAAGATTCAGTTTGGATAAACGTGTTATAATTGAATATATACTATACCTCCTTGGAGAATAATGCCAATATTGAAGCGTTTTCCCCTGAAATCCACTACTTCAGGCTGTTTGATCGATAAATCTGGAAAAACAATCACACTGGTGTAAACAAGTTTGACAGCAGAACTCTACCTCTGGAAACATACGAAGTGACACGGCTGGTTTTTAAGTCGTGCCGTGATTTGTTTTGTTCTCGCCGTACCTTCGCTTGTTTTCCCAGTGCATGACAGAACACTCATGTGAGCTACGTCTGTTTCTCTCTTCTCATCTTTGCTCTGTTTATGAATTGGAAATGATTGAATTTGACTTCTAGATTCACATCTTGCTGGGATATTTTGTGTGTGGATTTTTTTATTCTGCTTGATTCAGGGGTGATGCCAAATTATAAGAAGAGAAAAgagagttttttttgtttagttttttttctttttctcatgTCTTTGGGTTTTGAAGATGGTTGCTCTTCTTGATTCCTTTTGTGCCTGAGGTTTcaggttgagtgtgtgtgtgtgtgtgcgtgtatgtgtgtttttgtataaGTGCATTGAtcagatcagtttttttttatttcatggctGCTCGGAATCTTCAGGAGTCAGGATGCGACGAAATTGAGGGTTGTTATTTTTGAGTGGCATGTAAAAAGCGACGTACTTTGGAGTTATGCACAGAAATCTGTGTTTAGGCTGACAGCGGTTACACACTGCAATATTTCGTAAGGATTGTAAATAGTATAAGCATGACAGGTTGGTAGTTTATTGCTTAATCCACAGTGAGAGTTTAGGAGTATGGGTGAGGATTATACTAAAAAAAACTAAGGGTATATATACCATTATATACCATTCAATcgataaataaaacatttgcaattatgtaa

Function

symbol description
chmp2bb Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to act upstream of or within vacuolar transport. Predicted to be located in cytosol and late endosome membrane. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in gut; nervous system; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; chromosome 3-linked frontotemporal dementia; and frontotemporal dementia. Orthologous to human CHMP2B (charged multivesicular body protein 2B).

GO:

id name namespace
GO:0007034 vacuolar transport biological_process
GO:0015031 protein transport biological_process
GO:0032509 endosome transport via multivesicular body sorting pathway biological_process
GO:0045324 late endosome to vacuole transport biological_process
GO:0005768 endosome cellular_component
GO:0005771 multivesicular body cellular_component
GO:0000815 ESCRT III complex cellular_component
GO:0005829 cytosol cellular_component
GO:0031902 late endosome membrane cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2539 Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to act upstream of or within vacuolar transport. Predicted to be located in cytosol and late endosome membrane. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in gut; nervous system; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; chromosome 3-linked frontotemporal dementia; and frontotemporal dementia. Orthologous to human CHMP2B (charged multivesicular body protein 2B).

Ensembl:

ensembl_id ENSDARG00000002190

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000676 True 1986 mRNA 0.40 6 33558555 33569245

Neighbor

gene id symbol gene type direction distance location
XLOC_000394 NA coding upstream 39732 33517802 ~ 33518823 (+)
XLOC_000393 dhrsx coding upstream 71180 33383644 ~ 33487375 (+)
XLOC_000392 mxra5a coding upstream 223823 33322174 ~ 33334732 (+)
XLOC_000391 prkx coding upstream 274866 33217911 ~ 33283689 (+)
XLOC_000390 BX322647.1 coding upstream 341837 33215241 ~ 33216718 (+)
XLOC_000396 htr1fb coding downstream 64941 33634186 ~ 33635304 (+)
XLOC_000397 znf654 coding downstream 78437 33647682 ~ 33663705 (+)
XLOC_000398 arl13b coding downstream 98991 33668236 ~ 33694795 (+)
XLOC_000399 nsun3 coding downstream 127925 33697170 ~ 33722780 (+)
XLOC_000400 CU915566.1 coding downstream 165773 33735018 ~ 33735134 (+)
XLOC_000388 CU915272.1 non-coding upstream 852328 32706109 ~ 32706227 (+)
XLOC_000386 CU462859.1 non-coding upstream 1044451 32513989 ~ 32514104 (+)
XLOC_000383 BX901898.1 non-coding upstream 1540440 32017437 ~ 32018115 (+)
XLOC_000401 CT573012.1 non-coding downstream 397912 33967157 ~ 33967273 (+)
XLOC_000403 dre-mir-734 non-coding downstream 553635 34122880 ~ 34122972 (+)
XLOC_000407 CR848003.1 non-coding downstream 830995 34400240 ~ 34400354 (+)
XLOC_000408 NA non-coding downstream 881414 34450659 ~ 34454447 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000049_03214802_03219475 CHMP2B.L, CHMP2BA, CHMP2BB, CHM2B, CHMP2B, CHMP2B.S coding CI01000049 null 3214524 ~ 3219586 (+)