adam17a (adam17,LOC103360542,LOC102778206)


Basic Information

Item Value
gene id adam17a
gene name adam17,LOC103360542,LOC102778206
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053131.1
NCBI id CM020928.1
chromosome length 36057207
location 19149872 ~ 19165640 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039785076.1
ATGTTTTCCACTCGCTGCCCTTACTTCCGGGTAtctaagctaactagctagctgtcCAGACGACAAACTGAATTACCTTGTGACAATGACAGCACTAGCATAGTTGACTGAGCTGGCTGAAAATGAGGAGCATAGTTTTAATTGCCTTGCTGGTTCCTTGTTGGGTCAACAGTGCAATTAAATCAAGAGTTAATACGGAAGAGGATCACGAAGAAAACCCCGAGTTCGATGCTCTGAACTCCATCCTGTCAGATTTTGAGGTGCTCCCATTGTCAGGCCTCCAGCTGCACTCTGTAAGGAAAAGGGACGTCCACACCCAGTCTCACCTGGAGCGCCTGGTGAGCTTCAGGGCCCTGCACAGaaatTTCAAGCTTTACTTGACCACCAACACAGACCTTTTCACTGACAACTTTAAAGCGGTGTTTGTTGATAAACATGGAAGCGAGGAAAACTACGATGTTCATCTTCAGAACTATTTCACTGGACATGTTGTAGGAGAGGAGAATTCACGTGTGCAGGCACACATAGAAGGAGATGAGTTTTCTGCTCACATTCTAACTGATGCAGCAGAGTACAACGTAGAGCCCCTGTGGAGGTTTACAGATTCCCCAGCTGATGGCAGGTTGCTGGTTTATCGCTCAGATGACATCAGGAATCTGAGCCGCATCGTCTCTCCAAAAGTGTGTGGTTACATCCACGCAGAGGCTGAAGAGCTGCTGCCAGAGACTGCCAGGGATTTGGATGGGCAGGAGGAGGTGGACCAAGAAAAGGGGTCCCaccacagagagaagagacaggctcaCGATCACAAGAAGAATACCTGCCCCTTGTTGCTAGTTGCAGATTACCGCTTCTTCAAACACATGGGCCGCGGACAAGAGAGCGTCACTCTCAACTACCTGatTGAGCTGATTGATCGAGTTGATGACATTTATAGGAACACAACCTGGGATGATGAATTCAAAGGCTATGGGGTCCAGATCCATCAGATTATCATAAACAAGGAGCCTACAAAGCCTCCCCCTGGCCAAGCTGGCACCGGCTGGGTCCACTATAACATGGAAAACAGCCCTGTGAGTGGAAAGGCGGTCTGGGACGTAAAGAGACTTCTGGAGCAATTCAGCTCAGACATAGCTGATAACGCCTCCACTGTATGTCTGGCCCACCTGTTCACCTACCAGGATTTCGACGAGGGCACGCTAGGGCTAGCGTACGTGGCCCCCTCCAAACCTCAGGCACTGGGTGGCCTCTGCCCAAAAcCATACTACCCATCTCACTCTGTAAAGAAGCCCAGTTACCTCAACACAGGCCTGACCAGCACCAAGAACTATGGCAAAACCATCCTAACAAAGGAGGCAGATTTGGTAACCACTCACGAGCTGGGCCATAACTTTGGAGCAGAGCACGATCCTGACAACATCGCTTACTGTGCTCCCAGTGACGACCAGGGCGGGAAGTTTGTCATGTACCCTATAGCTGTGAGCGGAGACCATATCAACAACAAGCGCTTCTCCAACTGCAGCAAGATCTCCGTAGGAAAGACGTTACGTTTCAAGGCTCCCGTGTGTTTCAAGGAGAGGAACAGTAAGGTGTGTGGGAACTCCAGAGTGGAGGATGGGGAGGAGTGCGACCCCGGGCTACTCCACCTCAACGAAGACCCCTGCTGCTCAGCCGACTGCAAATTCAAAGGCGGTGCACAGTGCAGCGACCGAAACAGCCCTTGTTGTAGGAATTGCAAGTTTGAGCTCGCAAGAACGAGGTGCCAGGAACCCATTAATGCTACCTGTAAAGGCATATCCTCCTGCACAGGCAACAGCAGTCAGTGTCCACCCCCTGAAAACGCTGCTGACGACACAGTGTGTGTGGACAACGGCCGGTGTCTCAATGGAGAATGCAACCCTTTCTGCGAGGCCATGCAGAAACTTAAGTCCTGTGCTTGCAATGAGACGGAGAACTCCTGTAAAGTGTGCTGCAGGGGAAAAGGTGGCGCCTGCTCTCCCTTCATCCAGACCAATGGCAGTTTTCTTTTCCTTCGCAAAGGAAAACCCTGCACTGTGGGCTTCTGTGACGGGAACGGCAAGTGCATGAAACAGGTGCAGGACGTGATCGAGAGGTTGTGGGATTTTATCGACAAGCTGGATATTAACACATTTGGGAAGTTTCTGGCTGATAACATAGTGGGCTCTGTCGTGGTGTTTTCACTTGTCTTCTGGATTCCTCTCAGTATCCTGGTTCACTGTGTGGACAAACGACTTGACCAGCAGTATGAGGAGAACACAAAGTCCTTCTATTACCCTCCAAGCCAGATGGTGGAAGTTTGTAGTAGAGCTCCCGCCATAGAGTCAAGAAATGCTGAGCAACCTCGAGTCGGCGGCGGTGCGCATCGTCAAGCCTCCTCAGCCTCTCTCATCCTCCGTCGGCCGGACCGCGCCCTTCTCCCTGCCCCCTCAGCAGCAGAGCCAGGTCGCTGCCTCTCTCGCGTCCAGCACCAGTACCCAGGCCCCCGACCCGAGCTACGGCGCCACCCAGGACAGCGCAGGGGGGCCGCGGATGGACACCATCCAGGAGGACACCAGCAGCGACTCTCACCTGGGAGAGGAGTGCCTGTCGGACGATTTCACAACCGCAGGAGCCTGCTCGTCGGCTACGAAATCCTCCTACGAGGATCTGACAGAGCAGAACCCCGCAGCCAGGGACCGGCGGCGCCTCAAGAGGCAGGACTGCTTTGAGGCGGACACAAAAGAGACTGAGTGCTGAGATGAAATGACCAGtgctttttgtttaaaagcaaCAACACTTGCAACACATACCTGATGTGTGTTTAAGGGAACATGCAAATAACATGcagtgtcattaaaaaaaaatgtaaaatcccAAATCAGACGGCAATTGTTCAAAGGTAATAGCATACGTGTTTTACAGGTCAGATTTGGTGTTAAACAGAACAAAGGACAACATGAGATGTGGATATTATTCAGTCAGCTTCAACTTGGATTGAACCACCACACAGATTATACATGAGAAGTCACTATAAGAAGTAAGTAGTTACTGGTGAATTCATGTTTTTGTGGATAAATGGTTTCTGAATATGCATTatgaaaacatacacacaaaaacataaaactgaCACACATAGATCCCAAAGCTCTATCCAATTTGGCCAGTGtgtcttgttaaaaaaaaaaaaaaaaaaaatttaaactatGATTGTGGATTATAacttgaaaaaagaaatgttaacaGCTTCAGCCTGGCCTTTTCTCTCCTAAATGCTCGTTCAAAGTACTGTCTTCATAGCACAACAGTTTAACAGTCaaattatgtaatatattatTAATTGTGTAGTTATTTTaccataaaaagaaaacattttggtGTGATCTATTAAGCAACAAACGTTGACTTAAACTGAGTTTTGTCCTAAATCTCTGTGTCATAACTACACTTGGAAGTATTTTTTCACGTCACTGGAGCATTGAAAtgcgttttgttttttgtttttttacatgttcTTAATGTGCTGTGTCATTaatggtttctttttttattgtaggTTTGTATAATCTTTTGACACCTTTGTACTTATGATGCAACATTTTAATACTGTGCAGGGACAAGTGGTAGTCTACTCAGTATTTCATTTGTCTGTCCAGCTGTTGAAACTTTAAGAGGTTATATCGTGTGTATGAAACATGGTGCCTTTTCTGATTTAGTGCCTAACTGTTATGAGTCAACTTTGATTTCTGTGCAAAACTTCCAGTAGTTGAACATGAATCTGGACAATCtggaaattaataaaaaaaaaaaattccaaaggTGCTCAAATGTTATTTATACGCTTTGTTTTCTGTCCTTGTGCCAATGTGACTTGTGCACCTCActgttattacatgctgtctcaccACTGTTGCCTGCTGTGTCACATGTTAAAattgtaaaatatgtatttaactGTAGGTCAAGAAAAAAAACCGTGTAGCTAACAGTGACTACTGGGTAGATGTGAACGGTTACACAATGAGCAGATGTCCTGTGTCATATTCTGATTATGTTTATTCTTAATGTTTCTCTCTTTAAGTTCCTTGCTTGCATTACCTACACACACctcaaaataaaaatctttgTGCATTTTAAA
>XM_039785077.1
TGTTTTCCACTCGCTGCCCTTACTTCCGGGTAtctaagctaactagctagctgtcCAGACGACAAACTGAATTACCTTGTGACAATGACAGCACTAGCATAGTTGACTGAGCTGGCTGAAAATGAGGAGCATAGTTTTAATTGCCTTGCTGGTTCCTTGTTGGGTCAACAGTGCAATTAAATCAAGAGTTAATACGGAAGAGGATCACGAAGAAAACCCCGAGTTCGATGCTCTGAACTCCATCCTGTCAGATTTTGAGGTGCTCCCATTGTCAGGCCTCCAGCTGCACTCTGTAAGGAAAAGGGACGTCCACACCCAGTCTCACCTGGAGCGCCTGGTGAGCTTCAGGGCCCTGCACAGaaatTTCAAGCTTTACTTGACCACCAACACAGACCTTTTCACTGACAACTTTAAAGCGGTGTTTGTTGATAAACATGGAAGCGAGGAAAACTACGATGTTCATCTTCAGAACTATTTCACTGGACATGTTGTAGGAGAGGAGAATTCACGTGTGCAGGCACACATAGAAGGAGATGAGTTTTCTGCTCACATTCTAACTGATGCAGCAGAGTACAACGTAGAGCCCCTGTGGAGGTTTACAGATTCCCCAGCTGATGGCAGGTTGCTGGTTTATCGCTCAGATGACATCAGGAATCTGAGCCGCATCGTCTCTCCAAAAGTGTGTGGTTACATCCACGCAGAGGCTGAAGAGCTGCTGCCAGAGACTGCCAGGGATTTGGATGGGCAGGAGGAGGTGGACCAAGAAAAGGGGTCCCaccacagagagaagagacaggctcaCGATCACAAGAAGAATACCTGCCCCTTGTTGCTAGTTGCAGATTACCGCTTCTTCAAACACATGGGCCGCGGACAAGAGAGCGTCACTCTCAACTACCTGatTGAGCTGATTGATCGAGTTGATGACATTTATAGGAACACAACCTGGGATGATGAATTCAAAGGCTATGGGGTCCAGATCCATCAGATTATCATAAACAAGGAGCCTACAAAGCCTCCCCCTGGCCAAGCTGGCACCGGCTGGGTCCACTATAACATGGAAAACAGCCCTGTGAGTGGAAAGGCGGTCTGGGACGTAAAGAGACTTCTGGAGCAATTCAGCTCAGACATAGCTGATAACGCCTCCACTGTATGTCTGGCCCACCTGTTCACCTACCAGGATTTCGACGAGGGCACGCTAGGGCTAGCGTACGTGGCCCCCTCCAAACCTCAGGCACTGGGTGGCCTCTGCCCAAAAcCATACTACCCATCTCACTCTGTAAAGAAGCCCAGTTACCTCAACACAGGCCTGACCAGCACCAAGAACTATGGCAAAACCATCCTAACAAAGGAGGCAGATTTGGTAACCACTCACGAGCTGGGCCATAACTTTGGAGCAGAGCACGATCCTGACAACATCGCTTACTGTGCTCCCAGTGACGACCAGGGCGGGAAGTTTGTCATGTACCCTATAGCTGTGAGCGGAGACCATATCAACAACAAGCGCTTCTCCAACTGCAGCAAGATCTCCGTAGGAAAGACGTTACGTTTCAAGGCTCCCGTGTGTTTCAAGGAGAGGAACAGTAAGGTGTGTGGGAACTCCAGAGTGGAGGATGGGGAGGAGTGCGACCCCGGGCTACTCCACCTCAACGAAGACCCCTGCTGCTCAGCCGACTGCAAATTCAAAGGCGGTGCACAGTGCAGCGACCGAAACAGCCCTTGTTGTAGGAATTGCAAGTTTGAGCTCGCAAGAACGAGGTGCCAGGAACCCATTAATGCTACCTGTAAAGGCATATCCTCCTGCACAGGCAACAGCAGTCAGTGTCCACCCCCTGAAAACGCTGCTGACGACACAGTGTGTGTGGACAACGGCCGGTGTCTCAATGGAGAATGCAACCCTTTCTGCGAGGCCATGCAGAAACTTAAGTCCTGTGCTTGCAATGAGACGGAGAACTCCTGTAAAGTGTGCTGCAGGGGAAAAGGTGGCGCCTGCTCTCCCTTCATCCAGACCAATGGCAGTTTTCTTTTCCTTCGCAAAGGAAAACCCTGCACTGTGGGCTTCTGTGACGGGAACGGCAAGTGCATGAAACAGGTGCAGGACGTGATCGAGAGGTTGTGGGATTTTATCGACAAGCTGGATATTAACACATTTGGGAAGTTTCTGGCTGATAACATAGTGGGCTCTGTCGTGGTGTTTTCACTTGTCTTCTGGATTCCTCTCAGTATCCTGGTTCACTGTGTGGACAAACGACTTGACCAGCAGTATGAGGAGAACACAAAGTCCTTCTATTACCCTCCAAGCAGTCAAGAAATGCTGAGCAACCTCGAGTCGGCGGCGGTGCGCATCGTCAAGCCTCCTCAGCCTCTCTCATCCTCCGTCGGCCGGACCGCGCCCTTCTCCCTGCCCCCTCAGCAGCAGAGCCAGGTCGCTGCCTCTCTCGCGTCCAGCACCAGTACCCAGGCCCCCGACCCGAGCTACGGCGCCACCCAGGACAGCGCAGGGGGGCCGCGGATGGACACCATCCAGGAGGACACCAGCAGCGACTCTCACCTGGGAGAGGAGTGCCTGTCGGACGATTTCACAACCGCAGGAGCCTGCTCGTCGGCTACGAAATCCTCCTACGAGGATCTGACAGAGCAGAACCCCGCAGCCAGGGACCGGCGGCGCCTCAAGAGGCAGGACTGCTTTGAGGCGGACACAAAAGAGACTGAGTGCTGAGATGAAATGACCAGtgctttttgtttaaaagcaaCAACACTTGCAACACATACCTGATGTGTGTTTAAGGGAACATGCAAATAACATGcagtgtcattaaaaaaaaatgtaaaatcccAAATCAGACGGCAATTGTTCAAAGGTAATAGCATACGTGTTTTACAGGTCAGATTTGGTGTTAAACAGAACAAAGGACAACATGAGATGTGGATATTATTCAGTCAGCTTCAACTTGGATTGAACCACCACACAGATTATACATGAGAAGTCACTATAAGAAGTAAGTAGTTACTGGTGAATTCATGTTTTTGTGGATAAATGGTTTCTGAATATGCATTatgaaaacatacacacaaaaacataaaactgaCACACATAGATCCCAAAGCTCTATCCAATTTGGCCAGTGtgtcttgttaaaaaaaaaaaaaaaaaaaatttaaactatGATTGTGGATTATAacttgaaaaaagaaatgttaacaGCTTCAGCCTGGCCTTTTCTCTCCTAAATGCTCGTTCAAAGTACTGTCTTCATAGCACAACAGTTTAACAGTCaaattatgtaatatattatTAATTGTGTAGTTATTTTaccataaaaagaaaacattttggtGTGATCTATTAAGCAACAAACGTTGACTTAAACTGAGTTTTGTCCTAAATCTCTGTGTCATAACTACACTTGGAAGTATTTTTTCACGTCACTGGAGCATTGAAAtgcgttttgttttttgtttttttacatgttcTTAATGTGCTGTGTCATTaatggtttctttttttattgtaggTTTGTATAATCTTTTGACACCTTTGTACTTATGATGCAACATTTTAATACTGTGCAGGGACAAGTGGTAGTCTACTCAGTATTTCATTTGTCTGTCCAGCTGTTGAAACTTTAAGAGGTTATATCGTGTGTATGAAACATGGTGCCTTTTCTGATTTAGTGCCTAACTGTTATGAGTCAACTTTGATTTCTGTGCAAAACTTCCAGTAGTTGAACATGAATCTGGACAATCtggaaattaataaaaaaaaaaaattccaaaggTGCTCAAATGTTATTTATACGCTTTGTTTTCTGTCCTTGTGCCAATGTGACTTGTGCACCTCActgttattacatgctgtctcaccACTGTTGCCTGCTGTGTCACATGTTAAAattgtaaaatatgtatttaactGTAGGTCAAGAAAAAAAACCGTGTAGCTAACAGTGACTACTGGGTAGATGTGAACGGTTACACAATGAGCAGATGTCCTGTGTCATATTCTGATTATGTTTATTCTTAATGTTTCTCTCTTTAAGTTCCTTGCTTGCATTACCTACACACACctcaaaataaaaatctttgTGCATTTTAAA

Function

symbol description
adam17 Enables PDZ domain binding activity; metalloendopeptidase activity involved in amyloid precursor protein catabolic process; and signaling receptor binding activity. Involved in several processes, including positive regulation of cell migration; regulation of signal transduction; and response to bacterium. Located in several cellular components, including apical plasma membrane; cell surface; and membrane raft. Is integral component of plasma membrane. Colocalizes with cell-cell junction; focal adhesion; and ruffle membrane. Implicated in Alzheimer's disease; inflammatory bowel disease; and type 2 diabetes mellitus. Biomarker of renal fibrosis.

NR:

description
disintegrin and metalloproteinase domain-containing protein 17-like

GO: NA

KEGG:

id description
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039785076.1 True 4135 mRNA 0.46 20 19149872 19165640
XM_039785077.1 False 4097 mRNA 0.46 19 19149872 19165639

Neighbor

gene id symbol gene type direction distance location
LOC120548926 NA coding downstream 3929 19144915 ~ 19145943 (-)
mboat2a mboat2,LOC103371588,LOC100698509 coding downstream 98312 19004319 ~ 19051560 (-)
kidins220a NA coding downstream 146409 18956042 ~ 19003463 (-)
cmpk2 cmpk2 coding downstream 479178 18666225 ~ 18670694 (-)
myo6b LOC103377973 coding downstream 916546 18194096 ~ 18233326 (-)
LOC120548680 ywhaq,LOC101171621,LOC105927645 coding upstream 3329 19168969 ~ 19178357 (-)
lrr1 lrr1,LOC102779237 coding upstream 82807 19248447 ~ 19254808 (-)
LOC120549153 LOC103360532,LOC104953601 coding upstream 91540 19257180 ~ 19261951 (-)
itpka itpka,LOC102776846 coding upstream 220310 19385950 ~ 19396487 (-)
prlh2r LOC104960382,LOC103360548,LOC104921600 coding upstream 281164 19446804 ~ 19453237 (-)
G203983 NA non-coding downstream 6717 19142950 ~ 19143155 (-)
G203952 NA non-coding downstream 195223 18907716 ~ 18954649 (-)
G203941 NA non-coding downstream 234018 18800332 ~ 18915854 (-)
G203944 NA non-coding downstream 399493 18750018 ~ 18750379 (-)
G203874 NA non-coding downstream 485296 18664270 ~ 18664576 (-)
G204060 NA non-coding upstream 123238 19288878 ~ 19289329 (-)
G204062 NA non-coding upstream 124606 19290246 ~ 19290738 (-)
G204064 NA non-coding upstream 129629 19295269 ~ 19297723 (-)
G204102 ivd non-coding upstream 236269 19401909 ~ 19403085 (-)
G204138 NA non-coding upstream 335198 19500838 ~ 19501060 (-)
itgb1bp1 itgb1bp1 other downstream 17019 19128755 ~ 19132853 (-)
G203836 NA other downstream 965298 18182055 ~ 18184574 (-)
LOC120549177 nt5e other downstream 1019464 18123139 ~ 18130408 (-)
znf292a znf292,LOC103355984,LOC100696383 other downstream 1066098 18071484 ~ 18083774 (-)
ppp2r5ca ppp2r5c,LOC106937856,LOC102790868 other downstream 1443493 17681603 ~ 17706379 (-)
ppm1aa ppm1a other upstream 635635 19801275 ~ 19830929 (-)
itpk1b itpk1,LOC102785853 other upstream 876340 20041980 ~ 20090103 (-)
zdhhc22 zdhhc22 other upstream 1629226 20794866 ~ 20797775 (-)
G204685 coq6 other upstream 1686456 20852096 ~ 20853084 (-)
LOC120548683 NA other upstream 1825297 20990937 ~ 20992688 (-)

Expression


Co-expression Network