hsd17b4 (hsd17b4)


Basic Information

Item Value
gene id hsd17b4
gene name hsd17b4
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053117.1
NCBI id CM020914.1
chromosome length 43979800
location 25233215 ~ 25259169 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039803496.1
GCGGAGATTTAGTTTTAAGTATGTGAGCCAGATTATTAACAGCTTGTGCATGagtttttatttctgttgtatTCGCTGCCCGGCAGTTAAAATCGACATCTTGCTAACCGCTAACACTGGCGAAAAAGGCCTTGGCAGAGAATATGCACTAGCTTTTGCTGAAAGAGGAGCCTCAGTTGTAGTGAATGACCTTGGGGCTGACACTAAAGGGGGTGGAAAGAGTTCTGCAGCTGCTGATAACGTGGTGGAGGAGATAAGAGCGAAGGGAGGCAAGGCCGTGGCAAACTATGATTCTGTAGAAGATGGAGAAAAGTTGATCCAATCAGCACTGGATGCATTTGGAAGAATAGATGTTGTTGTAAACAATGCTGGGATCCTTCGTGACCGATCATTTGCGAGGACGAGTGATTTGGACTGGGACCTGATTCAAAGAGTTCACTTGAGGGGCTCTTTCTTGGTGACTCGAGCTGCTTGGAACCACATGAAAAACCAAAAGTTTGGCAGAATCATCATGACGGCTTCAGCCGCAGGCATCTATGGTAACTTCGGCCAGGCCAACTACAGTGCTGCCAAGCTGGGCATGCTGGGGCTGGCAAACACTTTGGCCATCGAAGGACGCAAGTACAACATCCACTGCAACACTATTGCTCCTGTTGCTGGATCACGCCTCACAGAGACTGTCATGCCCCCAGaCCTTGTGGCATCTCTGAAGCCTGAGTATGTTGCTCCCATGGTCCTCTGGCTCTGTCATGAACAATGCCAAGAAAGTGGAGCACTGTTTGAGGTCGGTGCAGGCTGGATTGGTAAATTGCGCTGGGAGCGCTCCCAGGGCTGCATTGTGAGACAGAAGAACCAACCCATGACTCCTGAGGCTGTCCGGGACCAGTGGGACAAAATCTGTGATTTCACAGATGCCACCAAGCCTACTAGCGTACAAGAGTCTCTGCAGTCGGTTGTGGATGTGCTGTCTCGAGTGGAGTTGGAGGAAGAAGTCAGTGCCAATCCaacagctgctgctgcctctgctTCAGGGATCAATCCTACTGAAGCAGTGGGACAAAAACTACCACCGAGCACGTTCACCTTCACCCACACCCAGTGTATTCTCTATGCATTGGGGGTCGGCATGTCCACCAAGGACCCAGACCATCTGagGTTCCTGTATGAAGGCCATGAAGACTTCAGCTGTCTCCCCACCTTTGGGGTCATTACCTCCCAGGCAGCCATGATGGATGGTGGGCTGAGCTCAATCCCTGGACTCAACATAGATTTTACACAGGTATTGCATGGAGAGCAGTATCTGGAGCTTTACAAACCTTTACCAACCTCAGGTACACTTACCTCTGAGTGCACCATAGCAGACGTGTTGGACAAAGGATCTGGAGCTGTCATCCTCTTGGACGTGAACACCTACAGCGGCGACGAGCTGATCTGCTACAACCAGTTTTCAGTGTTTGTGGTCGGAGCCGGAGGGTTTGGAGGGAAAAGAACTTCGGAGAAAGCCAAAgctCCCCTGCCTCCACCTAAACGGGCACCAGATGCGGTGGTGATTGATTCCACCACAAGAGACcaaGCGGCCTTGTACAGGTTGAGTGGAGACTGGAACCCTCTCCATATAGACCCCAGCTTTGCTGCCATGGGAGGCTTCAAGGCTCCCATCCTCCATGGCTTGTGCTCATTTGGCTTTGCGGCGAGACACGTGCTCAAGCAGTATGCTGACAACGATCCCTCCAGATTCAAGGCCATCAAGgtTCGCTTTGCAAAGCCGGTGATGCCGGGTCAGTCACTTCAGACTGAGATGTGGAAGGAAGGCAACAGAATTCACCTCCAGTGCAAAGTGAAGGAGACTGATGCTGTTGTGCTAAGTGGGGCCTATGTGGATTTACATGGCACATCAGAGGCTTCTCCAGAAAATCTCACTCAAGGAGGGGGCCTTCAGAGTGAGCTGGTATTTGCAGAGATTGGGCGTCGTATTAAAGACACGGGCTCAGAGTTGGTGAAGAAGGTGAATGCTGTGTTCGGCTGGGAGATCACCAAAGCGGGCAAGAACCCGGCTGCACAGTGGACCATTGATTTGAAGAACGGCAGCGGCTCCTTGCACAGAGGCCCTTACAGTGGGAAGGCGGATGTGACCTTCACCGTGTCAGATGAAGACTTCATGGAGGTGGTGCAGGGGAAACTCAACCCTCAGAAGgCGTTCTTCTCTGGCAAGCTGAAGGTTCGAGGGAACATCATGCTGAGTCAGAAGCTGGAGGTCATCCTGAAAGACTACGCCAAGCTGTGAGCTCCTCAGCCAACCAATCAGATGACTCTAGGAACTAACCAACCTACCTGCTCTCTCCGGCTGTGTACTTACATGCTTTGCCTCTCCAGGGTAAAGCTTAAAAAAATCACCCAGTAAGATGAATACTGCTTCAGAATGACTTCTGTACATTAACTTTCAAATACTTGATCAAATACGAGGGTTTTCTTCATTGTATCGCATGGATCCAGATATACTTTGATGActggagagaggaaacaagatttaaaaaaaaaaaagaagttttcGTTAGAAGCAATAATTTCGTGTCATTTCAGCTGGTTAGAATGTATTTGGTTGGGTCCTTATGGTCCGTCCCTGCTACATGTGCACTTAACACACCTGCCTTTGAATATCCAAATAAGAAATCAAGCATTAGTTTATTTCATTCACACAATCTATTAACTCAAACTGCTAACTATAACTTACTGTATGTACCTGATACTGCGATCTCAACAGAACCCTAGTGAGATGTGTAAAAATGTAGTTTGCTAGTTATGAAAAATAATGATTTTCACTTAATTTTAATGTCAACTGTAAAGAAATTCAATGATTACTCTTCTATGAAAATAAAGTACTTAAGACTAAAAGCTCA
>XM_039803497.1
CGTAATTGCGGAAGTGGAAGTTGTCGAAGTTCACCCTCATCCTGCTGTCTCTGACATTTGTGTTGCTCTTGTAGCCACTGTGCTGTGAATGTTCAGAAAGAGATATTAATTAACTCACAgggatgtctttgtcattcGAGGGAAGAGTCGTGCTTGTCACCGGCGCTGGAGGAGGCCTTGGCAGAGAATATGCACTAGCTTTTGCTGAAAGAGGAGCCTCAGTTGTAGTGAATGACCTTGGGGCTGACACTAAAGGGGGTGGAAAGAGTTCTGCAGCTGCTGATAACGTGGTGGAGGAGATAAGAGCGAAGGGAGGCAAGGCCGTGGCAAACTATGATTCTGTAGAAGATGGAGAAAAGTTGATCCAATCAGCACTGGATGCATTTGGAAGAATAGATGTTGTTGTAAACAATGCTGGGATCCTTCGTGACCGATCATTTGCGAGGACGAGTGATTTGGACTGGGACCTGATTCAAAGAGTTCACTTGAGGGGCTCTTTCTTGGTGACTCGAGCTGCTTGGAACCACATGAAAAACCAAAAGTTTGGCAGAATCATCATGACGGCTTCAGCCGCAGGCATCTATGGTAACTTCGGCCAGGCCAACTACAGTGCTGCCAAGCTGGGCATGCTGGGGCTGGCAAACACTTTGGCCATCGAAGGACGCAAGTACAACATCCACTGCAACACTATTGCTCCTGTTGCTGGATCACGCCTCACAGAGACTGTCATGCCCCCAGaCCTTGTGGCATCTCTGAAGCCTGAGTATGTTGCTCCCATGGTCCTCTGGCTCTGTCATGAACAATGCCAAGAAAGTGGAGCACTGTTTGAGGTCGGTGCAGGCTGGATTGGTAAATTGCGCTGGGAGCGCTCCCAGGGCTGCATTGTGAGACAGAAGAACCAACCCATGACTCCTGAGGCTGTCCGGGACCAGTGGGACAAAATCTGTGATTTCACAGATGCCACCAAGCCTACTAGCGTACAAGAGTCTCTGCAGTCGGTTGTGGATGTGCTGTCTCGAGTGGAGTTGGAGGAAGAAGTCAGTGCCAATCCaacagctgctgctgcctctgctTCAGGGATCAATCCTACTGAAGCAGTGGGACAAAAACTACCACCGAGCACGTTCACCTTCACCCACACCCAGTGTATTCTCTATGCATTGGGGGTCGGCATGTCCACCAAGGACCCAGACCATCTGagGTTCCTGTATGAAGGCCATGAAGACTTCAGCTGTCTCCCCACCTTTGGGGTCATTACCTCCCAGGCAGCCATGATGGATGGTGGGCTGAGCTCAATCCCTGGACTCAACATAGATTTTACACAGGTATTGCATGGAGAGCAGTATCTGGAGCTTTACAAACCTTTACCAACCTCAGGTACACTTACCTCTGAGTGCACCATAGCAGACGTGTTGGACAAAGGATCTGGAGCTGTCATCCTCTTGGACGTGAACACCTACAGCGGCGACGAGCTGATCTGCTACAACCAGTTTTCAGTGTTTGTGGTCGGAGCCGGAGGGTTTGGAGGGAAAAGAACTTCGGAGAAAGCCAAAgctCCCCTGCCTCCACCTAAACGGGCACCAGATGCGGTGGTGATTGATTCCACCACAAGAGACcaaGCGGCCTTGTACAGGTTGAGTGGAGACTGGAACCCTCTCCATATAGACCCCAGCTTTGCTGCCATGGGAGGCTTCAAGGCTCCCATCCTCCATGGCTTGTGCTCATTTGGCTTTGCGGCGAGACACGTGCTCAAGCAGTATGCTGACAACGATCCCTCCAGATTCAAGGCCATCAAGgtTCGCTTTGCAAAGCCGGTGATGCCGGGTCAGTCACTTCAGACTGAGATGTGGAAGGAAGGCAACAGAATTCACCTCCAGTGCAAAGTGAAGGAGACTGATGCTGTTGTGCTAAGTGGGGCCTATGTGGATTTACATGGCACATCAGAGGCTTCTCCAGAAAATCTCACTCAAGGAGGGGGCCTTCAGAGTGAGCTGGTATTTGCAGAGATTGGGCGTCGTATTAAAGACACGGGCTCAGAGTTGGTGAAGAAGGTGAATGCTGTGTTCGGCTGGGAGATCACCAAAGCGGGCAAGAACCCGGCTGCACAGTGGACCATTGATTTGAAGAACGGCAGCGGCTCCTTGCACAGAGGCCCTTACAGTGGGAAGGCGGATGTGACCTTCACCGTGTCAGATGAAGACTTCATGGAGGTGGTGCAGGGGAAACTCAACCCTCAGAAGgCGTTCTTCTCTGGCAAGCTGAAGGTTCGAGGGAACATCATGCTGAGTCAGAAGCTGGAGGTCATCCTGAAAGACTACGCCAAGCTGTGAGCTCCTCAGCCAACCAATCAGATGACTCTAGGAACTAACCAACCTACCTGCTCTCTCCGGCTGTGTACTTACATGCTTTGCCTCTCCAGGGTAAAGCTTAAAAAAATCACCCAGTAAGATGAATACTGCTTCAGAATGACTTCTGTACATTAACTTTCAAATACTTGATCAAATACGAGGGTTTTCTTCATTGTATCGCATGGATCCAGATATACTTTGATGActggagagaggaaacaagatttaaaaaaaaaaaagaagttttcGTTAGAAGCAATAATTTCGTGTCATTTCAGCTGGTTAGAATGTATTTGGTTGGGTCCTTATGGTCCGTCCCTGCTACATGTGCACTTAACACACCTGCCTTTGAATATCCAAATAAGAAATCAAGCATTAGTTTATTTCATTCACACAATCTATTAACTCAAACTGCTAACTATAACTTACTGTATGTACCTGATACTGCGATCTCAACAGAACCCTAGTGAGATGTGTAAAAATGTAGTTTGCTAGTTATGAAAAATAATGATTTTCACTTAATTTTAATGTCAACTGTAAAGAAATTCAATGATTACTCTTCTATGAAAATAAAGTACTTAAGACTAAAAGCTCA

Function

symbol description
hsd17b4 Predicted to enable 17-beta-hydroxysteroid dehydrogenase (NAD+) activity; 3-hydroxyacyl-CoA dehydrogenase activity; and enoyl-CoA hydratase activity. Acts upstream of or within embryonic organ development and neuron development. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Orthologous to human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4).

NR:

description
peroxisomal multifunctional enzyme type 2

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016491 oxidoreductase activity molecular_function
GO:0032934 sterol binding molecular_function

KEGG:

id description
K12405 HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039803496.1 False 2897 mRNA 0.48 25 25233498 25259169
XM_039803497.1 True 2943 mRNA 0.48 25 25233215 25259169

Neighbor

gene id symbol gene type direction distance location
atxn2 atxn2 coding upstream 93427 25107957 ~ 25139788 (+)
ostf1 ostf1 coding upstream 144569 25080307 ~ 25088646 (+)
LOC120560335 LOC104920830,LOC101074081,LOC103362722,LOC101475228,LOC102784348,LOC101160076 coding upstream 209527 25019069 ~ 25023688 (+)
loxhd1b LOC108233688,LOC105931393,LOC106513687,LOC106924721 coding upstream 232751 24974336 ~ 25000464 (+)
ptger4a LOC103360740,LOC104967800 coding upstream 270737 24958162 ~ 24962478 (+)
sema6a sema6a,LOC102790561 coding downstream 76855 25336024 ~ 25445140 (+)
cdo1 cdo1,LOC102791980 coding downstream 308535 25567704 ~ 25573107 (+)
LOC120560598 NA coding downstream 341987 25601156 ~ 25622051 (+)
spef2 LOC104950669 coding downstream 366835 25626004 ~ 25646477 (+)
LOC120560771 ugt3a2,LOC108233592 coding downstream 387946 25647115 ~ 25653156 (+)
G64392 NA non-coding upstream 23045 25209924 ~ 25210170 (+)
LOC120560056 NA non-coding upstream 192317 25034709 ~ 25040898 (+)
G64287 NA non-coding upstream 340698 24876562 ~ 24892517 (+)
G64279 NA non-coding upstream 370485 24860249 ~ 24862730 (+)
LOC120560123 NA non-coding upstream 714342 24514819 ~ 24518873 (+)
G64450 NA non-coding downstream 547 25259716 ~ 25302920 (+)
G64489 NA non-coding downstream 246995 25506164 ~ 25506568 (+)
LOC120560635 NA non-coding downstream 288854 25548023 ~ 25552264 (+)
G64495 NA non-coding downstream 293770 25552939 ~ 25555781 (+)
G64578 NA non-coding downstream 403858 25663027 ~ 25663385 (+)
cdc14b cdc14b,LOC102776968,LOC103141798,LOC106948523 other upstream 395767 24823718 ~ 24837448 (+)
prxl2c aaed1 other upstream 410149 24821314 ~ 24823066 (+)
G64108 NA other upstream 1539924 23692662 ~ 23693291 (+)
LOC120560905 clg12h9orf3,LOC103358904,LOC102294417,LOC101470200,LOC102214270 other upstream 1670930 23487967 ~ 23562285 (+)
G63905 NA other upstream 2303010 22929899 ~ 22930205 (+)
LOC120561182 LOC104948667,LOC104930137,LOC103397628,LOC103366370,LOC107092578,LOC102226292,LOC106956829,LOC106919698,LOC103470079,LOC103141747 other downstream 425795 25684964 ~ 25696576 (+)
LOC120560031 LOC104941040,LOC103357154,LOC102795853 other downstream 655110 25914279 ~ 25915577 (+)
LOC120560359 NA other downstream 666918 25926087 ~ 25928596 (+)
nsd3 whsc1l1 other downstream 1099951 26359120 ~ 26383843 (+)
G64814 cldn5,LOC103357131 other downstream 1153700 26412869 ~ 26414597 (+)

Expression


Co-expression Network