AMCG00000288 (l2hgdh)


Basic Information

Item Value
gene id AMCG00000288
gene name l2hgdh
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030141.1
NCBI id CM030141.1
chromosome length 22147039
location 9501693 ~ 9508924 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00000288
GTCAAGGGTGGTGTTGTGAAAGGAACAGGCAAGCCGCTCAGGTGTTGCGCTCGGTGCCGGTGTGTGCAGGCGGCCTCCTgtgctctctgtctgtccccgCTGTGCACGGCTCTCAGCTGCGGTAATGATCCGATCTGCCCGCAGCATCGCAGCCTCTGTGGCGTTTCTTACAAGACCAAAACATAAGTCTACGGTGCAATGCATCCTTAACAGCACTATCAGGCACAGCTCCTATGATGTGGCAGTGGTGGGGGCTGGCATCGTGGGGCTGGCCACGGCGCGGGAGCTAATCCTGAGACACCCCTCTCTGAGCTTTATcatcctggagaaggagaaggagctgGCGTCTCACCAGAGCGGACACAACAGCGGAGTGATCCACAGCGGGATTTACTACAAGCCGGGCTCCCTCAAGGCCAAGCTGTGTGTGCGGGGCGCTACCCTCGCCTACGAATACTGCGACAAAAAGGGGGTGCCCTACAAGAGGTGTGGCAAGTTGATCGTGGCGGTGGAGCAGGAGGAGGTGCCCCGGCTGCGGGCCCTGTACCAGCGCGGCCAGGAGAACAGTGTGCGCGACCTCAGGATGATTGACGCCAAGGAGATCCGCGAGAGGGAGCCCTACTGCCGGGGTCTGATGGCTCTGGATTCGCCCTACACTGGCATTGTGGACTGGCGGCTGGTGGCGCTGACCTACGCCAAAGATTTCCAAGATGCGGGCGGTACCGTGCTGACTGAGTTTGAGGCGGCAGACATTGCCATGGTGGCTGAAAGCCCTGCTGGCAgAATGAAGTATCCCATTGAAATCAGAAGTTCAAAgGGCGAGGGGGTGCGGTGTCGCTACGTGCTGACCTGCGGGGGCCTGTACTCTGACCGCCTCTCCCAGATCTCGGGCTGCAGCTCCGAGCCACGCATCGTCCCCTTCCGAGGAGACTACCTGGTTCTCAAGCCCGAGAAGCACTACCTGGTCAAGGGCAACATCTACCCTGTACCTGACCCCCGTTTCCCTTTCCTGGGGGTGCACTTCACGCCGCGGATGGACGGAAATGTGTGGCTGGGGCCCAACGCGGTCCTGGCCTTCAAACGGGAGGGCTATCGGATCTACGACTTCAACCCCCGAGACTTCGCCGACGCACTGAGCTTCAGGGGTCTGCGGAAGCTGGTGTTGAAGAATGTTGTTTATGGGATGGGTGAGATGTACAGAGGCATTTTCATGAGCGCACAGGTGAAACTGCTGCAGAAATACATCCCAGAACTCACGGTTAACGACGTTCTCCGGGGCCCTGCAGGGGTGCGGGCGCAGGCTCTGGACCGCGACGGTAACCTGGTGGATGACTTTGTGTTCGACGGCGGTGTCGGGGCCGTGGGCAGCCGCGTTCTACACGTGCGCAACGCCCCCTCACCGGCCGCCACCTCCTCTCTGGCCATCGGGGAGATGATCGCCGATGAGGTGCAGAGCAGGTTCAGCCTGTAGTCTGTGCTGGTGGCAGTAGCAGCTGTGCAAGCCCCTCCTACTATGCAAGCAAAGGCACCAATCGCAACCCATCCCATCTCTTCTGAAACCCCCCCAATGTGCTGCTGCACTTGCTTGGGGTGGGTTACAAGTCCTCAGAAACTTGAAAAGGAGAAGTCAAGAATAATACTTCAAAAATGACTGGGGTGCAAATGACGTCTCCTTAGGAAATTGTAGTATCCAACCAGCAGCAACTGCAATACTAACACATGAGCCCATAATGGGGAGGCACTCTTCCTTTGTCATTGTTCGCTTCAGTATAATTACTTCTGAATCAGGAAAATTGCATACGATCTATGTTAAATCAAACCAGTTagcacaaataaaaatcaaacttttttttatattgaagaTGCTAGACTTTGCACTTTACCAAGTCTAAAGCTgttgttttcaattacattgTTCCATTTCTTCCGGAACAGGATCTCTCCCGTTCTCCCAATGGAGGTTTTTGTAACTGCTTTGTACCCTCACAACTGAAAAAGACCTCGCTAGGTCTTATTTGGTGCTTAAGTCTGGATTGCTGTGAGCCTGGAAAAGCTTGAAAGCATGATTTGGACGGAAAGTCCCACAGTACAGTGCGCCTGCTCCTTGAACCCAAAACTAGTGCTGCACGCAAAAACCTCATCTGGAAAAGAGACaagctgtttttcatttgaacagGAGGGACCGCTCCCCAGTGGAATTCAGTGATATCCAGAAAGTACAGCTCTGATCCtccagggtgtgtgtgtcatttaccactacaaatgtataattgaatCAACTTTGAAGCTTCCTAGGGTCTTATAAAGGTAATTAGTAAGAAAACCTGCAGCTCAAGAAGACTCAGTTCTGTCTTTCTACCCAAAAGgttatattaattgttttatagtggtttggtttttatttgttgtgttcgTCTTAATCTAAAACCAGCAGCTAGTTTAATTCATAATGCAGCTGTGactctgtgatttattttaaatgtctgtacATATCTTTGGTCAGACAAAGTGTGCTACCTTACAATGCTGCCTTAACTACTCACAGGTGTGTGCATCTTATTCAGAACGAATCCCCTAATGTTTAAAGGGGATGTTCGGGATGTCATTTTCTCAGGATGCAGTGTCTCCTTTACCAAGTGAAGTCTCACTGAAAGTAAATCACATCTGGGCATTTGTAAAGAATCTGTGTACTATAATACCttttggaacaaaaaataatattctcttatttttttctgaaaataaaaccgaTTCTGTACCAGTATTGAgagatttttcaattttgtactgtttttt

Function

symbol description
l2hgdh Predicted to enable (S)-2-hydroxy-acid oxidase activity and 2-hydroxyglutarate dehydrogenase activity. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; L-2-hydroxyglutaric aciduria; cerebellar ataxia; hereditary spastic paraplegia; and visual epilepsy. Orthologous to human L2HGDH (L-2-hydroxyglutarate dehydrogenase).

NR:

description
PREDICTED: L-2-hydroxyglutarate dehydrogenase, mitochondrial

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016491 oxidoreductase activity molecular_function

KEGG:

id description
K00109 L2HGDH; 2-hydroxyglutarate dehydrogenase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00000288 True 2796 mRNA 0.51 10 9501693 9508924

Neighbor

gene id symbol gene type direction distance location
AMCG00000287 cdkl1 coding upstream 325 9487917 ~ 9501368 (+)
AMCG00000277 LOC106517965,LOC107602930 coding upstream 74151 9414677 ~ 9427542 (+)
AMCG00000278 NA coding upstream 89361 9378563 ~ 9412332 (+)
AMCG00000274 pygl,LOC104938237 coding upstream 138259 9355981 ~ 9363434 (+)
AMCG00000273 trim9,LOC102776798 coding upstream 146545 9331536 ~ 9355148 (+)
AMCG00000280 NA coding downstream 48594 9557518 ~ 9560476 (+)
AMCG00000283 NA coding downstream 179823 9688747 ~ 9705449 (+)
AMCG00000282 NA coding downstream 212966 9721890 ~ 9747008 (+)
AMCG00000293 NA coding downstream 319165 9828089 ~ 9840429 (+)
AMCG00000294 smoc1 coding downstream 356063 9864987 ~ 9876944 (+)
G149253 NA non-coding upstream 216542 9280063 ~ 9285151 (+)
G149172 psmc6 non-coding upstream 485542 9013371 ~ 9016151 (+)
G149059 NA non-coding upstream 827907 8668980 ~ 8673786 (+)
G149056 NA non-coding upstream 916726 8584488 ~ 8584967 (+)
G149055 NA non-coding upstream 917686 8583648 ~ 8584007 (+)
G149359 LOC103376870 non-coding downstream 211023 9719947 ~ 9776988 (+)
G149416 slc39a9,LOC107721951,LOC107664419 non-coding downstream 448789 9957713 ~ 9962571 (+)
G149415 NA non-coding downstream 464124 9973048 ~ 9975172 (+)
G149450 NA non-coding downstream 512498 10021422 ~ 10021853 (+)
G149454 NA non-coding downstream 520770 10029694 ~ 10030786 (+)
AMCG00000285 map4k5 other upstream 15004 9440061 ~ 9486689 (+)
AMCG00000249 acta1,actc1,LOC103383882,LOC105024319 other upstream 916420 8579717 ~ 8585273 (+)
AMCG00000251 NA other upstream 926569 8572936 ~ 8575124 (+)
AMCG00000217 gpx2 other upstream 2138986 7359278 ~ 7362707 (+)
AMCG00000215 max,LOC107668248,LOC103457350 other upstream 2177242 7313872 ~ 7324451 (+)
AMCG00000286 sos2 other downstream 5898 9514822 ~ 9546411 (+)
AMCG00000281 cpsf2,LOC106608196 other downstream 52633 9561557 ~ 9591088 (+)
G149424 NA other downstream 460400 9969324 ~ 9970801 (+)
G149525 LOC100846954,LOC107575789 other downstream 1025666 10534590 ~ 10535137 (+)
AMCG00000352 NA other downstream 2456631 11965555 ~ 11995026 (+)

Expression


Co-expression Network