AMCG00015716 (nr3c2,LOC107550687,LOC107742541,LOC107670737)


Basic Information

Item Value
gene id AMCG00015716
gene name nr3c2,LOC107550687,LOC107742541,LOC107670737
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030132.1
NCBI id CM030132.1
chromosome length 32980562
location 17890492 ~ 17919482 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00015716
TCATCATTAAGAAATTCCTCTTCCGGTTCCTCTGCCCCTGCAAAGGTGTGTTTGGTCTGTGGGGATGAAGCATCTGGATGTCATTATGGTGTTGTTACTTGTGGCAGCTGTAAGGTTTTCTTCAAAAGAGCCGTAGAAGgTCAGCACAACTACCTGTGTGCAGGGAGAAATGACTGCATCATTGACAAGATTCGAAGAAAGAACTGCCCAGCCTGCAGAGTACGAAAGTGTCTGCAGGCTGGAATGAACTTGGGAGCACGGAAGTCAAAGAAGCTTGGGAAATTAAAAGGAGTGAGTGAGGAGCAGCAACTTCAGAGCCCAAAGGAAGGCCAGACGTATTTGGCTACAGAAAAGGACTTGAGTGCCAGTACCACCCTGGTCCCTCACGTACCAGGTGTGACGCCATACCTGGCTCCGTCCATCTGCAGCATCCTGGAAATCGTCGAGCCAGAAATTGTTTATGCAGGGTATGACAACAGCCAACCAGACACCACAGACCACCTGCTCTCCAGTCTAAATCAGCTAGCAGGAAAACAGATGATCCGAGTTGTCAAGTGGGCAAAGGTACTTCCAGGATTCAGAAGTTTGCCAATTGAGGACCAAATCACCCTCATTCAATACTCTTGGATGTGTCTCTCTTCATTCGCCCTCAGCTGGAGGTCCTATAAACATACCAGTGGCCAGATGTTGTATTTTGCACCGGACCTTGTTTTCAATGAGGAAAGGATGAAGCAGTCGGCAATGTATGACCTGTGCCAGGGCATGCGCCAGGTGAGCCAGGAGTTTGTGCGGCTACAGCTGACCTATGAAGAGTTCCTGGCCATGAAAGTACTGCTGCTGCTAAGC

Function

symbol description
nr3c2 Enables steroid hormone binding activity and steroid hormone receptor activity. Acts upstream of or within cellular response to cortisol stimulus and multicellular organismal response to stress. Predicted to be located in nucleus. Is expressed in several structures, including blood; eye; heart; liver; and pleuroperitoneal region. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1 and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2).

NR:

description
mineralocorticoid receptor

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00015716 True 846 mRNA 0.49 5 17890492 17919482

Neighbor

gene id symbol gene type direction distance location
AMCG00015709 lrba,LOC107598261 coding upstream 442831 17416375 ~ 17447661 (+)
AMCG00015710 lrba coding upstream 505167 17351282 ~ 17385325 (+)
AMCG00015707 lrba,LOC106602365 coding upstream 559898 17318293 ~ 17330594 (+)
AMCG00015708 NA coding upstream 590046 17281679 ~ 17300446 (+)
AMCG00015705 NA coding upstream 654708 17186838 ~ 17235784 (+)
AMCG00015714 nr3c2,mra,mrb coding downstream 26007 17945489 ~ 17953069 (+)
AMCG00015715 prmt9 coding downstream 138400 18057882 ~ 18068675 (+)
AMCG00015726 slc10a7,LOC106591891 coding downstream 532895 18452377 ~ 18458170 (+)
AMCG00015728 NA coding downstream 758336 18677818 ~ 18682808 (+)
AMCG00015727 NA coding downstream 770256 18689738 ~ 18716514 (+)
G99933 NA non-coding upstream 52592 17837617 ~ 17837900 (+)
G99915 NA non-coding upstream 289584 17600703 ~ 17600908 (+)
G99867 NA non-coding upstream 424978 17450084 ~ 17465514 (+)
G99842 NA non-coding upstream 819438 17070583 ~ 17071054 (+)
G99840 NA non-coding upstream 822902 17067161 ~ 17067590 (+)
G99934 NA non-coding downstream 13517 17932999 ~ 17933328 (+)
G99932 NA non-coding downstream 35003 17954485 ~ 17956630 (+)
G100005 NA non-coding downstream 377557 18297039 ~ 18298304 (+)
G100046 NA non-coding downstream 708840 18628322 ~ 18630144 (+)
G100082 NA non-coding downstream 838580 18758062 ~ 18844449 (+)
AMCG00015703 rps3a,LOC106592945 other upstream 758717 17098459 ~ 17131775 (+)
AMCG00015687 NA other upstream 1391961 16494692 ~ 16498531 (+)
AMCG00015682 NA other upstream 1432650 16433443 ~ 16457842 (+)
G99624 NA other upstream 1759105 16131044 ~ 16131387 (+)
G99541 NA other upstream 2088858 15796950 ~ 15801634 (+)
G100007 NA other downstream 400574 18320056 ~ 18325904 (+)
AMCG00015725 smad1 other downstream 825405 18744887 ~ 18771966 (+)
G100338 herc3 other downstream 2347925 20267407 ~ 20268285 (+)
AMCG00015796 hspa12b,LOC107583310,LOC107697252,LOC107721672 other downstream 4759355 22678837 ~ 22683895 (+)
G101061 NA other downstream 6945607 24865089 ~ 24865552 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000049_04830811_04848245 NR3C2 coding CI01000049 null 4829836 ~ 4848501 (-)