eif2b3 (eif2b3,ei2bg,LOC107720854,LOC107700990,LOC107722074,LOC107599900)


Basic Information

Item Value
gene id eif2b3
gene name eif2b3,ei2bg,LOC107720854,LOC107700990,LOC107722074,LOC107599900
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035912.1
NCBI id CM008315.1
chromosome length 41032606
location 127085 ~ 146205 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007235357.3
AGTGAGCGGCTGGAGTTTCCCCCGGGCtgttagagagagaggcacGAGTGTCATCATGTTAGCCGCTCGTGAGCTAAATGAGATTAATAACAGAGATTAATTAACTGTATTAATCTGTGGATTCGATAATCTGATCATTAATATCAGCGGTTCGGTGATTAAACTGATCCCCGCTTTTCTCCCGCCGCTGTTTCACATCAGTATCGGATCAGACTGAGGGTTAAAGAGAGAGTTAGCCGGTTAGCTTCTGCTGCTAACAGCGGAGCTGCGCTCAGACGCACGgagttataataaatattaaataataaatattaaactgaCGTATTAATACCGCGGATCTCATCTGTACAGGTGAATAAAGATTAGAAAttgcatatttatataaaataaatgaagatggAGCTGCAGGCGGTGCTGATGGCTGCTGGTGGAGGATCCAGGATGATGGATCTCACCTACAACACCCCCAAACCTTTACTGCCGGTCGGGAACCGGCCGCTGATCTGGTACCCTCTCAACCTGCTGGAGAGAGCCGGCTTCGAAGAGGTTATAGTGATCACCACTAAAGAAGTGCAGAAGGCTCTGAGCACGGACCAGCGGCTGAAGCTGGATGTGAAGATGAAGCTGAATGTTGAGTGTATCCAGGAGGACGCTGATATGGGCACCGCTGATGCTCTGAGACACATCCAGCAGAAGTTGAAGACAGATATCCTGGTGGTGAGCTGTGACCTGATCACGGACGTGGCGTTGCATGAGGTGGTGGATCTGTTCCGTGCTCACAACGCCACGCTCTCCATGCTGATGAGTATGCACGAGTTCACGGAGACGGTGCCGGGCCAGAAGGGGAAGAAGAAAGCAGgTGAGCAGAGGGATTTTGTGGGCGTGGACAGTGCGGGGAAGCGGCTGCTCTTCATGGCGAATGAAGCTGATCTGGATGAGGGACTCATCATTAAGAAATCAGTGATGCGGAAACATCCCAGGATGCACATCAGAACAGGACTGCTGGATGCTCACCTGTACTGCCTGAAGAGATCTGTGGTTGACTTTTTAGTGGAGAATAaGTCTATCTCGTCTCTGAGAGGAGAGCTGGTGCCGTTTTTGGTGCGAAAGCAGTTCAGTAAGACCTCGATCTCCCGGCGGGAGGAAGATCACTCCGATCAGAGTCAGAAGAGAAAAGACGCGACTGCGGCTCTGGAGATCCTGTGCTGCACTAAAGATGAGGCTCTGCTGCAGTTGGCGAGCGAGCGGTCCTGCTGGAACGATCACAGCGGGGATATGAGCGAGGCGTACCACGGCGGCCGGCTGCGCTGCTACGCTCACATCATGCAGGAGGGAACGTGTTACCGAGTCAATACCCTCACCTCGTACGTGGAAGCCAATCGCGTGgCTCCCAAACTATTTGAAGAAGCTGCAGTTCATCCGTCAGCCGTGATCTCAGAGCGCAGTCAGGTTGGAGGTGACAGCATTATTGGAGCTTCCTGCCACATAGCAGACAAAACATCCATCAAACGCTCCACCATCGGAGCTTCCACCATCGTGAAGGAGAAAGTAAAAATCACCAACTCCATCATCATGAACAGCGTCACTATAGAAGAGGGGTGTAATATTCAGGGCAGCGTCAtctgtaacaacgctgtgattGGACGAGGTGCTGACATCAAATACTGCCTGGTGGGAAGCGGCCAGCGCATCGAGGCAGAGGCTGAAAGAACCAATGACGTGATCGTTGGGTCGGATCAGCTGATGGAGATCTAGAACCTGTGGGTGGAGAACCTGATGGAACCGGTGGATCTGATAGAAGCACCACCAGAAGAGAAGAAGATCTTGGTTCTTCTCCCTGAACCTGCCGGTTTTTACTGAATGTGTCcaaataaatctgaatttatTTACCTCA

Function

symbol description
eif2b3 Predicted to enable guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translational initiation. Predicted to be part of eukaryotic translation initiation factor 2B complex and guanyl-nucleotide exchange factor complex. Is expressed in eye and gut. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma).

NR:

description
translation initiation factor eIF-2B subunit gamma

GO:

id name namespace
GO:0051716 cellular response to stimulus biological_process
GO:0006413 translational initiation biological_process
GO:0043087 regulation of GTPase activity biological_process
GO:0014003 oligodendrocyte development biological_process
GO:0005851 eukaryotic translation initiation factor 2B complex cellular_component
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function
GO:0016779 nucleotidyltransferase activity molecular_function
GO:0003743 translation initiation factor activity molecular_function

KEGG:

id description
K03241 EIF2B3; translation initiation factor eIF-2B subunit gamma

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007235357.3 True 1894 mRNA 0.51 13 127085 146205

Neighbor

gene id symbol gene type direction distance location
LOC103021456 ptch2,LOC107557169,LOC107700991,LOC107720855,LOC107599897,LOC107722076 coding downstream 3413 95083 ~ 123672 (-)
LOC111194215 NA coding downstream 37555 88370 ~ 89530 (-)
cenpl cenpl coding upstream 27036 173241 ~ 176666 (-)
brinp2 brinp2,LOC107720848,LOC107658350,LOC107700985,LOC107562711,LOC107722070 coding upstream 140145 286350 ~ 423788 (-)
pappa2 NA coding upstream 571818 718023 ~ 750580 (-)
tnn NA coding upstream 845688 991893 ~ 1026466 (-)
trove2 trove2 coding upstream 944032 1090237 ~ 1102807 (-)
G137611 NA non-coding downstream 48722 75676 ~ 78363 (-)
G137610 NA non-coding downstream 57340 68959 ~ 69745 (-)
G137648 klhl20,LOC102300935 non-coding upstream 15491 161696 ~ 163945 (-)
G137659 NA non-coding upstream 47149 193354 ~ 193998 (-)
G137710 NA non-coding upstream 134911 281116 ~ 386357 (-)
G137719 NA non-coding upstream 272556 418761 ~ 420399 (-)
G137721 NA non-coding upstream 280030 426235 ~ 426528 (-)
LOC111194217 pappa2,LOC107722077,LOC107678935,LOC107726923,LOC107658303,LOC107558342 other upstream 549698 695903 ~ 717323 (-)
G138199 plk3,LOC107563563,LOC107722069,LOC107658359,LOC107726922,LOC107557223 other upstream 904327 1050532 ~ 1101493 (-)
LOC103042176 zgc:55943,c7h1orf21,LOC103042176,LOC108430752,LOC107709356,LOC107671715,LOC107559369,LOC107593773,LOC107727521 other upstream 2331490 2477695 ~ 2486894 (-)
LOC103045355 LOC108430731 other upstream 2904195 3050400 ~ 3062759 (-)
LOC103025790 NA other upstream 2949396 3095601 ~ 3114686 (-)

Expression


Co-expression Network