dkk1 (dkk1)


Basic Information

Item Value
gene id dkk1
gene name dkk1
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035900.1
NCBI id CM008303.1
chromosome length 25652880
location 22368776 ~ 22371487 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007233996.3
ACCAGGGTCTGATGAAGCCTCAGAACACAGCTCAGCCAGCAGCTTAGCTCCAGGAGCTCCAGCGAACAGGAGAATATAGCGCACCGAGCACCAGCAGCACCTCCACCGCGGACTATCTGCGACCATGTGGCCGGCGGCGCTCTCAGCCCTGACCTTCACCCTGATCACTGCCACGGCGGCGGCGGCCGGGGGGCTCTTCAACTCCAACGCCATCAAGGTGGGTGCACCTGTGGAAAGCTCGGATCAGGCGGTGAGCGAGAGCCCACAGGTGTTCCCCGTGGATGAGGGCAGTCAGAACTTCGCCACCGACACCATGCAGCCTCTTGTATGTGTGGTGGATGAACAGTGCGCTGAAGACGAGTTCTGTTTCCGATCGCGCGGCGTTTGCCTCCAGTGTAAGAAAAGGAGAAAGCGCTGCATCCGGGATGCTATGTGTTGCCCTGGAAACCACTGCAACAACGGAGTGTGTCAACCAAACGACCCTGACATTGCCCTCCAAGCAGGAGTAGAAGAATTTGTGCTCGTTAGCGCCCCCCATGAGGAGAACGCCACACTGGTACTGCAGCCCAAGTCACCGGTTCATAATCTAGCTCAAAACCTGAAAGgtCTTGAGGGCGAGACCTGCCTGAGGTCTTCTGACTGTGCGGAGGGGCTGTGCTGTGCTCGCCATTTTTGGTCAAAGATCTGCAAGCCTGTCCTAAAGGAGGGTCAGGTCTGCACCAAGCACAAGAGGAAAGGCACTCACGGACTGGAGATCTTCCAGCGCTGCGACTGCGATGAAGGCCTGTCCTGCCGGACGCAACGAGGAGACCACAGCAAGTCCTCTAGAAGCCTCCATACCTGCCAGAGACACTGAGAATCCAGTGGGATTTTGTTTGCGTAAAGCTTCTGGAAAGTGGGACCAatctgaaagaaagagaaaactcCATTACTGATGGATTTTGATGGATGAAGGgatgaaaggatggatggattatgATTGGGATACTCTTGTTCTTACTTCTTCCTGTCTACAGTTTGTATGTCAACATTGCAGAGTAGATATACATGTTTCTCTATGGAACTTGGCTTTTGATGGTTGCAGTACATTACTGTATTGTAAATACTAGGGAAGTTGGCacttaactcttttttttgtcaacaCAATGATTTTTGAGGATGAGGATTTTACCAAGCTTTTTCCagtttattgtaaatgtacataCAGATTTTCATGATCGTATAGAGTCTGATATAtgtctattttttattctaaataaagaGTTATGATATTTGATATTTCAAA

Function

symbol description
dkk1 Enables co-receptor binding activity; low-density lipoprotein particle receptor binding activity; and receptor antagonist activity. Involved in several processes, including regulation of cell fate specification; regulation of gene expression; and regulation of protein phosphorylation. Located in extracellular space and plasma membrane. Implicated in anodontia.

NR:

description
PREDICTED: dickkopf-related protein 1

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0021879 forebrain neuron differentiation biological_process
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process
GO:0003197 endocardial cushion development biological_process
GO:0043697 cell dedifferentiation biological_process
GO:0061011 hepatic duct development biological_process
GO:0070654 sensory epithelium regeneration biological_process
GO:0001889 liver development biological_process
GO:0048919 posterior lateral line neuromast development biological_process
GO:0007398 ectoderm development biological_process
GO:0030334 regulation of cell migration biological_process
GO:0030903 notochord development biological_process
GO:0005576 extracellular region cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005515 protein binding molecular_function

KEGG:

id description
K02165 DKK; dickkopf

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007233996.3 True 1285 mRNA 0.50 4 22368776 22371487

Neighbor

gene id symbol gene type direction distance location
prkg1 prkg1,prkg1b,LOC107695529,LOC106589397 coding upstream 18694 22097751 ~ 22350082 (+)
LOC111192422 NA coding upstream 270878 22070247 ~ 22097898 (+)
LOC103021762 asah2,LOC107598643 coding upstream 356971 21987804 ~ 22011805 (+)
LOC103023313 NA coding upstream 384492 21959447 ~ 21984284 (+)
sgms1 sgms1 coding upstream 418099 21938629 ~ 21950677 (+)
LOC111192392 LOC108416223 coding downstream 627192 22998679 ~ 23000623 (+)
tfam NA coding downstream 1016493 23387980 ~ 23396378 (+)
bicc1 bicc1,LOC107653928,LOC107695510 coding downstream 1047366 23418853 ~ 23594042 (+)
phyhipl phyhipl,phyhiplb,LOC107727060,LOC107746456,LOC107654056,LOC107695536 coding downstream 1257200 23628687 ~ 23685558 (+)
LOC111192424 NA coding downstream 2029631 24401118 ~ 24402659 (+)
G38379 NA non-coding upstream 14162 22353509 ~ 22354614 (+)
G38392 NA non-coding upstream 41703 22278954 ~ 22327073 (+)
G38391 NA non-coding upstream 116134 22252149 ~ 22252642 (+)
G38375 NA non-coding upstream 315107 22053359 ~ 22053669 (+)
G38330 a1cf non-coding upstream 352303 22013499 ~ 22016473 (+)
G38438 NA non-coding downstream 38904 22410391 ~ 22410651 (+)
G38439 NA non-coding downstream 47401 22418888 ~ 22419169 (+)
G38440 NA non-coding downstream 57914 22429401 ~ 22430016 (+)
G38460 NA non-coding downstream 243276 22614763 ~ 22617893 (+)
G38461 NA non-coding downstream 244060 22615547 ~ 22616453 (+)
plce1 plce1,LOC107743958 other upstream 1071953 21166568 ~ 21296823 (+)
lgi1 lgi1,lgi1b,LOC107743957,LOC107664615,LOC107598600,LOC107654035,LOC107708938 other upstream 1240012 21109080 ~ 21128764 (+)
G38079 kif22,LOC107664627 other upstream 1337979 21019169 ~ 21030797 (+)
G37943 NA other upstream 2210437 20155728 ~ 20158339 (+)
LOC103039215 ubtd1b,ubtd1,LOC108437310,LOC107720068 other upstream 2857335 19488899 ~ 19511441 (+)
trnar-ccu_1 NA other downstream 1375982 23747469 ~ 23747541 (+)
trnar-ccu_2 NA other downstream 1376084 23747571 ~ 23747643 (+)
trnar-ccu_3 NA other downstream 1376186 23747673 ~ 23747745 (+)
trnar-ccu_4 NA other downstream 1376288 23747775 ~ 23747847 (+)
trnar-ccu_5 NA other downstream 1376390 23747877 ~ 23747949 (+)

Expression


Co-expression Network