Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_009196 |
| gene name | drd2a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007126.7 |
| NCBI id | CM002899.2 |
| chromosome length | 48040578 |
| location | 22046557 ~ 22074315 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| drd2a | Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of cytosolic calcium ion concentration; and regulation of ion transport. Predicted to act upstream of or within dopamine receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be active in glutamatergic synapse. Predicted to be integral component of presynaptic membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; mental depression; migraine with aura; obesity; and type 2 diabetes mellitus. Orthologous to human DRD2 (dopamine receptor D2). |
| id | name | namespace |
|---|---|---|
| GO:0051967 | negative regulation of synaptic transmission, glutamatergic | biological_process |
| GO:0007186 | G protein-coupled receptor signaling pathway | biological_process |
| GO:0043266 | regulation of potassium ion transport | biological_process |
| GO:0007194 | negative regulation of adenylate cyclase activity | biological_process |
| GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway | biological_process |
| GO:0007212 | dopamine receptor signaling pathway | biological_process |
| GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway | biological_process |
| GO:0051481 | negative regulation of cytosolic calcium ion concentration | biological_process |
| GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway | biological_process |
| GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway | biological_process |
| GO:1901386 | negative regulation of voltage-gated calcium channel activity | biological_process |
| GO:0014059 | regulation of dopamine secretion | biological_process |
| GO:0007165 | signal transduction | biological_process |
| GO:0001963 | synaptic transmission, dopaminergic | biological_process |
| GO:0005887 | integral component of plasma membrane | cellular_component |
| GO:0098978 | glutamatergic synapse | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0099056 | integral component of presynaptic membrane | cellular_component |
| GO:0004930 | G protein-coupled receptor activity | molecular_function |
| GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go | molecular_function |
| GO:0004952 | dopamine neurotransmitter receptor activity | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-021119-2 | Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of cytosolic calcium ion concentration; and regulation of ion transport. Predicted to act upstream of or within dopamine receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be active in glutamatergic synapse. Predicted to be integral component of presynaptic membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; mental depression; migraine with aura; obesity; and type 2 diabetes mellitus. Orthologous to human DRD2 (dopamine receptor D2). |
| ensembl_id | ENSDARG00000056926 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00018094 | False | 2613 | mRNA | 0.44 | 8 | 22046557 | 22074315 |
| TCONS_00018095 | True | 1775 | mRNA | 0.45 | 7 | 22047004 | 22069107 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_009195 | NA | coding | downstream | 142331 | 21900306 ~ 21904226 (-) |
| XLOC_009194 | zgc:162608 | coding | downstream | 168561 | 21875545 ~ 21877996 (-) |
| XLOC_009193 | laynb | coding | downstream | 193566 | 21842638 ~ 21852991 (-) |
| XLOC_009192 | sik2b | coding | downstream | 209042 | 21779681 ~ 21837515 (-) |
| XLOC_009191 | si:dkey-40g16.6 | coding | downstream | 344240 | 21694388 ~ 21702317 (-) |
| XLOC_009197 | scn3b | coding | upstream | 59524 | 22133839 ~ 22147860 (-) |
| XLOC_009198 | NA | coding | upstream | 86610 | 22160925 ~ 22161978 (-) |
| XLOC_009199 | si:ch211-286b4.4 | coding | upstream | 90234 | 22164549 ~ 22251089 (-) |
| XLOC_009200 | CR936967.1 | coding | upstream | 186566 | 22260881 ~ 22260997 (-) |
| XLOC_009201 | zgc:194114 | coding | upstream | 228409 | 22302724 ~ 22304193 (-) |
| XLOC_009187 | BX663519.1 | non-coding | downstream | 506281 | 21521803 ~ 21540276 (-) |
| XLOC_009186 | NA | non-coding | downstream | 539021 | 21493852 ~ 21507536 (-) |
| XLOC_009185 | NA | non-coding | downstream | 676996 | 21355581 ~ 21369561 (-) |
| XLOC_009180 | CR626907.2 | non-coding | downstream | 936949 | 21079826 ~ 21109608 (-) |
| XLOC_009202 | NA | non-coding | upstream | 514189 | 22588504 ~ 22594885 (-) |
| XLOC_009203 | CR388121.1 | non-coding | upstream | 646450 | 22720765 ~ 22720881 (-) |
| XLOC_009204 | BX572079.1 | non-coding | upstream | 880702 | 22955017 ~ 22955132 (-) |
