XLOC_009980 (tmem67)


Basic Information

Item Value
gene id XLOC_009980
gene name tmem67
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 27564270 ~ 27581488 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019875
GTCATCAAGCGTCATCTGATCCTGCACCATGGCGACGGGGACGCGGAGCGCCTTGTTGTATAGTGTCTCCATTATAATTCTGTTAAAAATAAGCGTTTTCTCCTGCCAGCAGTTCTCCATATCATTTCGACAGCCTTCTGACTGTGGCGTTAACAGCTATTTTGATATTTCGAGCCTGTCTTGCGTGAAATGCGGGTCAAATCAAGTCAGCAGCAAATCAGGACTGGCATGTGAGTGTCAGGCTGGTTCCAGAGTGCTGGTCAGTAATGGGGTGTCTATCTTGTGCCAGCAGTGTCCTGATGCTGATCAGGTGGTCACCCAGGATGGATATGAATGTATTCGTTGTCCTGGAACTGTGGGGAAGGATGGCAAGTGTCAGTGTCCTGAGGGAAGTGTGCTGGTGGAGAGAGATGGGAATGGCAATCCCTTAATTGAAGCAAGGTGTCAAGCATGTAGTGCAACAGATCCTGCTTTTTCTGCCCCAGATATGAAAGGCAACAGGTGTGAGAGATGTGGGGACTCATTCATTAACTCATCTCAGTCTTGTGTTTGCGGCACTTCGAATACGCTGGCAGGAGGAATGTGCTTCCCTGCGAACAGTCTGCCTACCTCAGTTGCCTCAAGTGTTATTTTTAGCCAACTGACTCTCCCTGTCCAGTCAGCATGGTTTTCAAGCTTCATGTATTCTTCGGCCGCTGCATGTTTGTTGTTCTCTAACCGGACTGCATGTCAGTCTCTGGGAAACATGTGTGTTATGAACATGCACTCATCCAGCTCCATCAACAATGATGTCTGTGGTCTCTACAACACAATCTACAGAACAACAGCTGCTCAGGGCAGCAGCCAGGACATCTCCTACTGGAGGACAAACCTACCTTGGCTGTACTATGGAGATCAACCAGGGATGGCATCACAGGCTCTTCAGAATGAACCCCTTCCTGTTGGATTCAGCTTTAAAGGGGCACAAAAGAACACCAACATTGAGTTGCGAGCTGCTGTGTACTCAGTGCGTGGAGAGTTTCTGAGATGGGAAAGCGTTGGTAGAGGCAACCTTCAGCTCTGTCCAGACACCCCTACCAGACAACAGTCTGCCTTCAAATTCGGGACAGCCTACAAGCAGAGTTGTGTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTATGATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGTGCCTCTCCTAAATGCCAATCAGCAGTTTAACGGCCAGTTTGTCAATCAGGGATCTGACATGAGTAAATGGTTCCTGACCCGAAGGCTGATGCTTGTCGACACATTGAGTGGAAGAGAGAAGTCTATAAGTTCTTCACCCGTAGTTATACGAGTGGCTTCTGACATTAAGATCGGGTTTCAGCTGGTACCAAATACACAGAAGGGACAGGTTTACCCTCCACTGATGAGTGTGGCCTACTCGGATATACAGATCAAAGACCCCAGCACACAGACTGTTACTGTGACATTCTCTGTGGAGTATACAATGAACCAGGAAGAAGCTCGGATCAAAACTGATATTGCTCTTGGTGTGCTGGGTGGAGTGGCTGTTGTCCACTCTTTATTGAAGACAGCAAGCTGGAAAAGAAGAATCGCATCTCCTCTTATTGACTTGGAGACAATTATGAAGTTCTTGGTTTTCTATGCTGGAGaccttgcaaatgtttttttcatcATCACTGTTGGAACTGGCCTCTACTGGCTCATATTCTTCAAGGCCCAACTGTTTGTGTCCGTGTTGCTGCCATTGCCAGCTCAGGAGGAGCGTTTTGTTGTTTATGTTGGCTGTGCTTTTGCATTAAAGACTGTACAGTTTCTTCACAAGATTTTCGTTCAGCTCTCTGTGGATGTTTTCTTCATAGACTGGGAAAGACCTCGTGGAAAAACGACTAAACATGTGGAGGGATCCGGAGAAACAAAAAGTCAGGCGTCTCCTGTCAGTATCTGGAGGACTTATTTTGTGGCCAATGAGTGGAATGAGATTCAAACCATTCGCAAGATCAACCCCACTTTTCAAGTTATGGCTGTGCTCTTTTTTCTAGAGgttgtaGGCTTCTCAAATTTGGCTCTAAGAGATCCTTCGTCTAACCTGAATCGATCTGCTGAGGAATACACGCCTCCATACAGCCTCATACTCCGCTATGGTGTAGCTACTGCTATGTGGCTCTGCATTGGCTTAATACAGATGATATTCTTCACAGTGTTCCATGAACGGTTTGTTGAAGACAAGATTCGTCAGTTTGTGGATTTGTGCTCAATCAGTAATATCTCAGTTCTGCTGCTGTCTCATCGATGTTTTGGCTACTACATTCATGGGCGCTCTGTTCATGGTCATGCTGATACTAACATGGATGAGATGAACACTAACCTTAAGAGGGAGGCGgaGAATCTGTGTGGCCAAAGGGGACTTTTGCCAAACTCTGATACTCAGACGTTTCAGATTTCGATAACTAACCGTCTGCGAGCACAGTATGATCGGATAATCGAGCCAATCAGCAGGAGAAGAGGACCTTCAAGGTTGGTGGATGCTACAGCCAATCCATGCGAGCAAAGCACAAAAGCATACCATACTATGAACCGATTCCTGGGCTCTGTCATTGATCATGCACATCGTGAGATGGACTACATTGTGAAAGATAAGCTACTGTTTGAGAGAGTCATCGGTATGGAGTTCATAGAGCCGCTCGATAAAAGCATCTTTTATAATGATGATTCTCACTCATTCGCTGATGTCCTTTTTTATGGTAATGAGGGTGTGCTGTTGATCTTCGACACGCTCTTTTTCTGTGTGGTTGATCTGGGCAAGCAGAACTTCATTCTCGCAGCTGTGTTAACGTACCTTCAGCAAATGATATTTAGATTAATTCGAAATGGATTGGGCCGCAGGAACCTGGCCAACAAAACGCTAGTTGACAAACGATTTCTCATCTAGATCTTCATCTTATTGCACCATGACAGCCTTCAGGTTTCTTCTACcgaattttgtattgtttttatattaataataatttttttgtaatttctaaGACAGGATGTTGTTGAATctaatgtataaatgtttttatatttaagtatttttgatCAATTAAACAAGTTCTTGGTTTTTACACATGGCAGGCCTCATAAGTAAAACTGATGCTACATAAAA
>TCONS_00019876
AACACCAACATTGAGTTGCGAGCTGCTGTGTACTCAGTGCGTGGAGAGTTTCTGAGATGGGAAAGCGTTGGTAGAGGCAACCTTCAGCTCTGTCCAGACACCCCTACCAGACAACAGTCTGCCTTCAAATTCGGGACAGCCTACAAGCAGAGTTGTGTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTATGATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGTGCCTCTCCTAAATGCCAATCAGCAGTTTAACGGCCAGTTTGTCAATCAGGGTATAATATCCAATTATATATTTGATCATCAGATGTTAAGGCATTGCTATTTTATTATAGTGTTAACTCCTCATTTATTAGGATCTGACATGAGTAAATGGTTCCTGACCCGAAGGCTGATGCTTGTCGACACATTGAGTGGAAGAGAGAAGTCTATAAGTTCTTCACCCGTAGTTATACGAGTGGCTTCTGACATTAAGATCGGGTTTCAGCTGGTACCAAATACACAGAAGGGACAGGTTTACCCTCCACTGATGAGTGTGGCCTACTCGGATATACAGATCAAAGACCCCAGCACACAGACTGT

Function

symbol description
tmem67 Acts upstream of or within cilium assembly; cilium movement; and convergent extension. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of MKS complex. Predicted to be active in ciliary transition zone. Used to study ciliopathy and meningocele. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome (multiple); COACH syndrome; Joubert syndrome 6; Meckel syndrome 3; and nephronophthisis 11. Orthologous to human TMEM67 (transmembrane protein 67).

GO:

id name namespace
GO:0003341 cilium movement biological_process
GO:0007369 gastrulation biological_process
GO:0060271 cilium assembly biological_process
GO:0010826 negative regulation of centrosome duplication biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0060028 convergent extension involved in axis elongation biological_process
GO:0036038 MKS complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG:

id description
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-080716-1 Acts upstream of or within cilium assembly; cilium movement; and convergent extension. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of MKS complex. Predicted to be active in ciliary transition zone. Used to study ciliopathy and meningocele. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome (multiple); COACH syndrome; Joubert syndrome 6; Meckel syndrome 3; and nephronophthisis 11. Orthologous to human TMEM67 (transmembrane protein 67).

Ensembl:

ensembl_id ENSDARG00000076752

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019875 False 3193 mRNA 0.45 28 27564270 27581488
TCONS_00019876 True 614 lncRNA 0.45 4 27569837 27571351

Neighbor

gene id symbol gene type direction distance location
XLOC_009979 si:ch211-197h24.6 coding upstream 5374 27543308 ~ 27558896 (+)
XLOC_009978 invs coding upstream 61568 27442549 ~ 27502702 (+)
XLOC_009977 CR848817.1 coding upstream 148458 27415697 ~ 27415812 (+)
XLOC_009976 stx17 coding upstream 158810 27383717 ~ 27405460 (+)
XLOC_009975 nr4a3 coding upstream 194488 27345383 ~ 27369782 (+)
XLOC_009981 si:ch211-197h24.8 coding downstream 12210 27593698 ~ 27602512 (+)
XLOC_009982 si:ch211-197h24.9 coding downstream 22251 27603739 ~ 27609172 (+)
XLOC_009983 glipr2l coding downstream 33501 27614989 ~ 27622183 (+)
XLOC_009984 NA coding downstream 258439 27839927 ~ 27873367 (+)
XLOC_009985 znf804b coding downstream 376320 27957808 ~ 27998856 (+)
XLOC_009973 LO017763.1 non-coding upstream 357473 27206669 ~ 27206797 (+)
XLOC_009964 BX537166.1 non-coding upstream 920444 26640677 ~ 26643826 (+)
XLOC_009961 NA non-coding upstream 1030513 26531777 ~ 26533757 (+)
XLOC_009960 NA non-coding upstream 1053161 26509385 ~ 26511109 (+)
XLOC_009986 NA non-coding downstream 468066 28049554 ~ 28050028 (+)
XLOC_009987 NA non-coding downstream 688527 28270015 ~ 28371330 (+)
XLOC_009989 CR936250.1 non-coding downstream 806558 28388046 ~ 28388163 (+)
XLOC_009994 NA non-coding downstream 1078907 28660395 ~ 28667333 (+)

Expression


Co-expression Network