XLOC_037027 (epha3)


Basic Information

Item Value
gene id XLOC_037027
gene name epha3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 16449398 ~ 16618607 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00072884
ATGGCTGATGTTTTGCGAGTGATGTTACTTTTCAGATGTGTGgatttcataattttatttaTTAACCTATTGGACTCCAAAGCAAGCCAAGGAGAGCTGGGTTGGATATCATCCCCATCCCATGGGTGGGAGGAAATTAGCGGCGTGGATGAGCACTACACACCCATCCGGACTTTCCAGGTGTGCAACGTGATGGAATACAGCCAGAACAATTGGTTGAGGACCAACTGGATTCCTCGTAATTCTGCACAGAAGATCTATGTGGAGCTCAAGTTTACCCTAAGAGATTGCAATAGTATTCCCATGGTCCTGACCTGCAAAGAAACATTCAACTTACACTATCTGGAGACAGAAGAAGACCAGGGAAATAAGTTCCGTGAGCACCAGTTTTCCAAAATAGATACAATCGCCGCAGATGAGAGCTTTACTCAGATGGACCTAGGTGACCGCATTCTGAAGTTAAACACAGAGGTCCGTGAGGTGGGGCCCATGACTAAGAAGGGCTTCTACCTGGCTTTCCAGGACGTGGGAGCCTGTGTGGCCCTAGTGTCGGTGCGGGTGTACTTTAAAAAATGCCCTTTCACAGTGAGGAACCTGGCTATGTTTCCTGACACGGTTCCTACAGACTCTCAGTCACTGGTGGAAGTTAGGGGCTCCTGCGTCAACAATTCCAAGGAGGAGGATCCACCAAAAATGTACTGCAGTACCGAGGGAGAGTGGCTGGTGCCTATTGGGAAATGCCTGTGCAACATAGGTTACGAGGAGCGGGGAGTCGCTTGCCAAGCCTGCCGGCCCGGTTTCTATAAGGCTTCATCTGGGAACGTCAAGTGCTCCAAGTGTCCTCCACACAGCTACACACACCAGGAGGGATCTGTACACTGCGGCTGTGAGAAAAATTACTTTCGAGCAGACGAGGACCCTGCCTCCATGGCCTGCTCTCGTCCTCCCTCTGCCCCTCGCAATGTGATCTCTGCCATTAACGAGACCTCAGTGATTCTAGACTGGAACTGGCCAGCAGACAACGGAGGCAGAAAGGATGTAATATTTAACGTGGTCTGCAAGCGATGTTGGCCGGGTCCCAGACAGTGTGAACCCTGTCGAGGGGCTGTGCGCTTCCTGCCCCGTGCTtttggcctcactaacacaacCGTAACTGTGGCAGACCTCCTGGCACACACCAACTACACCTTTGAGATTGAGGCCCAAAATGGAGTGTCTTTTCAGGCCCCCACAATCCGCCAGTACGCTGCGGTCACCATCACTACAAATCAAGCAGCGCCATCTGCAGTGACTGTCATCAGGAAGGATCGAACATCAAGAAACAGCATCTCACTGTCTTGGATGGAGCCAGAGAGACCCAATGGAATAATTCTGGACTATGAGGTCAAATACTATGAGAAGCAGGAACAAGAGACGAGCTACACCATCCTGAGGTCGAAGGGTACAAATGTTACACTGAACGGACTGAAACCTGACACCACCTACCTGCTGCAGATCAGAGCTCGTACTGCTGCCGGTTACGGCAGCAGCAGCCGCAAGTTTGAGTTCGAGACCAGCCCAGACTCCTTTTCTATCTCCAGTGAGAACAGCCAAGTAGTGCTGATCGCTATCTCCTCCGCCGTGGCCATCATCCTCCTCACTGTAGTGCTCTACATTGTGATTAGCAGGTTTTGCAGGTACAGTAAGTCCAAACATCCGGACGAAAAGAGGCTGCCTTTTGGCAACGGCCACTTGAGACTGCCTGGCATTAAGACCTATGTGGACCCGCATACTTACGAAGACCCGAGTCAAGCCGTGCATGAATTCGCCAAGGAACTGGATGCGTCTAGTATTGCCATTGACAAAGTTGTTGGGGCAGGGGAGTTTGGAGAGGTGTGTAGTGGCAGACTGAAGCTGCCATCTAAGAAGGAGATCTGCGTGGCCATCAAGACACTCAAAGCTGGATACACAGAGAAACAAAGACGGGACTTTCTCAGTGAAGCGAGCATCATGGGACAGTTTGATCACCCTAACATCATCAGATTGGAGGGTGTGGTAACACGCAgTAAACCTGTGATGATAGTGACCGAGTACATGGAGAACGGCTCCTTGGATGGCTTCCTGCGAAAACACGACGCCCAGTTCACAGTGATTCAGCTGGTGGGCATGCTACGTGGCATTGCGTCTGGGATGAAGTATCTGTCGGATATGGGTTACGTGCACAGAGACCTAGCCGCTCGGAACATCCTGGTCAACAGCAATCTAGTGTGTAAAGTGTCAGACTTCGGCTTGTCCAGAGTGTTAGAGGATGACCCAGAAGCGGCCTACACAACAAGAGGTGGCAAGATTCCAATCCGATGGACTGCGCCAGAAGCCATCGCCTATCGCAAGTTCACCTCAGCCAGTGACGTATGGAGCTATGGGATTGTGCTATGGGAGGTCATGTCTTACGGAGAAAGGCCTTATTGGGAGATGTCCAATCAGGACgtAATAAAAGCAGTGGATGAAGGATATCGTCTTCCCCCACCCATGGAATGCCCTGCCACACTTTACCAGCTAATGctagactgctggcagaaagacAGAAACAACCGGCCGAAATTTGAACAGATTGTCAGCATTCTGGACAAGCTTATCCGCAACCCTAGCAGTCTGAAGATCACAGCCAGCACTGCTTCCAGACCGGTAAATTTACTTCTGGACAGGAACAGCACTGATATCACTTCTTTTCACACAATGGGAGATTGGCTGGAGAGTGCGAGGACGTTGCCCTGTAAAGATGCATTCAGCGGTGTTAGCTACAGCTCCTGTGATACACTGGCCAAAACCTCAGCAGAAATCTGTCTGACTGAAGTCAGACCAGCAGCCACGTGCCCTGAGTGGGAGCCATCCATGGGAATTACAACACTTTAA

Function

symbol description
epha3 Predicted to enable transmembrane-ephrin receptor activity. Acts upstream of or within mesoderm migration involved in gastrulation and somitogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in optic cup. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3).

GO:

id name namespace
GO:0007509 mesoderm migration involved in gastrulation biological_process
GO:0033674 positive regulation of kinase activity biological_process
GO:0001756 somitogenesis biological_process
GO:0007275 multicellular organism development biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007411 axon guidance biological_process
GO:0016310 phosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0043005 neuron projection cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005003 ephrin receptor activity molecular_function
GO:0005005 transmembrane-ephrin receptor activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004714 transmembrane receptor protein tyrosine kinase activity molecular_function

KEGG:

id description
ko04360 Axon guidance
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-010724-10 Predicted to enable transmembrane-ephrin receptor activity. Acts upstream of or within mesoderm migration involved in gastrulation and somitogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in optic cup. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3).

Ensembl:

ensembl_id ENSDARG00000039373

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00072884 True 2892 mRNA 0.51 17 16449398 16618607

Neighbor

gene id symbol gene type direction distance location
XLOC_037026 C9H3orf38 coding upstream 201300 16241656 ~ 16248098 (+)
XLOC_037025 BX323875.1 coding upstream 463601 15982344 ~ 15985797 (+)
XLOC_037024 BX469925.2 coding upstream 541578 15907033 ~ 15907820 (+)
XLOC_037023 NA coding upstream 542491 15901526 ~ 15906907 (+)
XLOC_037022 si:dkey-14o1.20 coding upstream 554897 15890558 ~ 15894501 (+)
XLOC_037028 NA coding downstream 157380 16775987 ~ 16776615 (+)
XLOC_037029 cln5 coding downstream 235514 16854121 ~ 16859169 (+)
XLOC_037030 NA coding downstream 607637 17226244 ~ 17227294 (+)
XLOC_037031 scel coding downstream 687555 17306162 ~ 17334658 (+)
XLOC_037032 NA coding downstream 718544 17337151 ~ 17343544 (+)
XLOC_037020 CR513782.1 non-coding upstream 878391 15567364 ~ 15571007 (+)
XLOC_037019 NA non-coding upstream 919941 15527611 ~ 15529457 (+)
XLOC_037037 NA non-coding downstream 1017774 17636381 ~ 17636674 (+)
XLOC_037038 AL929161.1 non-coding downstream 1044343 17662950 ~ 17663065 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000080_04517413_04566482 EPHA3 coding CI01000080 null 4516905 ~ 4566695 (-)
bowfin (Amia calva) AMCG00014257 epha3,LOC107549902,LOC107676997 coding CM030128.1 CM030128.1 6814181 ~ 6860542 (-)