erbb4a (erbb4a,erbb4,LOC107674013,LOC107707608,LOC107725343,LOC107667809,LOC107557316,LOC108440448,LOC101079286)


Basic Information

Item Value
gene id erbb4a
gene name erbb4a,erbb4,LOC107674013,LOC107707608,LOC107725343,LOC107667809,LOC107557316,LOC108440448,LOC101079286
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056699.1
NCBI id CM032068.1
chromosome length 31761587
location 5157979 ~ 5294440 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043240427.1
CCGGAATTCAGCGCAGAGTGATGACAGTCCCAACGCAGTCACATTTAGACAAGGAATAACTCACTTGCAGCTCTGTCATTAAATCAACTGATCCAGTTTTGCTTGCAGACATAAACCCAGGCGCAAGTCTAGACCATGCGCTCTATGTGAACAGCTGCGCAAAGACGCACAGGCTGAAAGACATTTGACAGCTCGCCAACGGGACACTGGAGTGGACATGTGAAGAAATGGATATGCAGCCTCTTCATGTGATCAAAATGCGATCTgacatcatcatcctcctcatcctcactgCTGTGATTGTTCCCCAGTGCACCTCGCAGTCAGTGTGTCCTGGCACTGATAACAAGCTCAGCACGCTGTCGGATTTGGACCAGCAGTACAAAACTCTTCGCAAGTTCTACGAGAACTGTGAGGTGGTCATGGGTAACCTGGAGATCACCAGCATTGAAAGAAACCGCAATCTGTCTTTCCTCAAGTCCATCCGTGAGGTGACGGGATACGTGTTGGTGGCTCTGAATCAGTTTGACTATCTTCCTCTGGAGAACCTGCGGATCATCCGAGGCACTAAACTGTATGAAGGACGATACGCTCTGGCCATCTTTCTCAACTACAGACGAGATGGCTACTTCGGCCTCAGACAACTCGGACTCAAGAACCTgacagAAATCCTGAACGGAGGTGTGTATGTGGATCAGAACAAGTTCTTGTGTCACGCTGACACCATCCACTGGAATGACATCATTAAGAACCCCCGTTCTGAACTTCTGGTGGTTCCTTCCAACAACAGCGGCAACTCATGCAGACGGTGTCACAGATCTTGTAATGGACGCTGCTGGGGTCACCAAGAAGACCAGTGCCAAAGCTTGACAAAGACGGTGTGCGCAGAGCAGTGTGATGGACGCTGTTTCGGTCCGTACGTCAGTAACTGCTGTCACCGTGAATGTGCAGGAGGCTGTTTTGGACCCAAAGACACCGACTGCTTCGCTTGTACCAACTTTAATGACAGCGGGGCCTGTGTGACGCAATGTCCTCAGCCATTCGTCTACAATCCAACAACCTTCCAGCTCGAGCACAATCCCAACGCCAAATACACCTATGGAGCGTTCTGTGTCAAGAAATGCCCACATAACTTTGTGGTGGATCACAGCTCTTGTGTCAGAGCCTGTCCGAGCAACAAGATGGAGGTGGAGGAAAATCACATCAAGATGTGCATCCCATGCACTGACATCTGTCCGAAAGTGTGTGACGGTATAGGTACCGGCAGTCTTCAGACGGCTCAAACTGTAGATTCCAGCAACATTGAGAAGTTTGTCAATTGCACCAAAATCAACGGCAACCTCATCTTCCTCATCACAGGCATTAAAGGGGACATGTTTCATGGCATAAAAGCTCTGGACCCTGATCGGTTAAATGTATTCCGCACCGTCAGAGAGATCACAGGTTTCTTGAACATTCAGTCTTGGCCGGAAAACATGACAGATCTTGGCGTTTTCTCAAACCTTGCCACCATCGGAGGACGCTCTCTGTATAGtggTATTTCTCTGCTGATCCTGAAGCAGCGCTGGATCTCTTCGCTGAAGTTTCAGTCTCTGAAAGAGATCAGCGCCGGTAACATCTACATGACCAACAACAGCCAGCTCTGCTTCTACAACACGGTGAACTGGACCAGTCTGTTCCGCACCAGCACCCAGAGAGCTCTGATCAAGAACAACAGGGACCCCAGAGACTGCACTAAAGAGCAGATGGTCTGTGATCCGTTGTGTTCGGAGGAAGGATGCTGGGGTCCCGGTCCAGACCAGTGTCTCTTGTGCAAATACTTCAGCCGAGGAAAGACGTGTGTCAAGTCCTGCAACTTATATTATggGGATGTTCGAGAGTACGCCAATGGCTCGGTTTGTGTTGAGTGTGACAGCCAGTGTGAAAAAGCCGGAGAGAAAAGCTTGACCTGCCATGGTCCGGGTCCAGATCACTGTGTGAAGTGCTTGCATCTCAAAGATGGACCCAACTGTGTGGAGAAATGCCCTGATGGTCTTCAGGGAGCAAACAGCTTCATCTTCAAATATGCTGAGACCAACAACGAGTGCCATCCGTGCCACCCCAACTGCACCCAGGGcTGTACTGGACCCAGAGTACAAGATTGCATTGGCATGCTAGACAGGACTCCTCTGATTGCAGCTGGGTTAATTGGGGGTCTCTTTGTGATGGTCATCATAGCTCTGGGTGTGGCTGTTTACGTCCGTCGAAAGAGCATTAAGAAAAAGAGAGCTTTGCGTCGTTTCCTGGAGACTGAGTTGGTGGAGCCGTTGACGCCCAGTGGTACAGCACCAAACCAAGCTCAGCTGCGAATACTGAAGGAAACTGAGCTCAAGAGAGTCAAGATTCTGGGAGCTGGAGCCTTTGGCATGGTCTATAAgGGAATCTGGGTTCCAGAAGGAGAAACTGTGAAGATTCCCGTGGCTATAAAGATACTCAATGAAAGTACAGGACCTAAAGCCAATGTGGAGTTCATGGATGAGGCACTGATCATGGCCAGCATGGAGCATCCTCATCTAGTGCGTCTTTTGGGGGTCTGCTTGAGTCCCACTATTCAGCTGGTAACTCAACTCATGCCCCACGGCTGCCTGCTGGACTACGTACATGAACACCAGGAGAACATCGGCTCCCAGCTGCTGCTCAACTGGTGTGTGCAGATCGCAAAGGGTATGATGTACCTAGAGGAGAGGCGTCTGGTGCACAGGGACCTCGCGGCCCGTAACGTCCTGGTGAAATCTCCAAACCACGTCAAGATCACTGATTTTGGACTCGCTCGACTGCTGGATGCTGATGAAAAGGAGTATAATTCGGACGGAGGGAAGATGCCAATCAAGTGGATGGCCCTGGAGTGCATTCATTACAGAAAGTTCACACATCAGAGTGATGTATGGAGTTATGGTGTGACTATCTGGGAGCTGATGACGTTCGGAGGAAAGCCCTACGATGGGATTCCCACACGCGAGATTCCAGACATCTTGGAGAAGGGCGAGCGTTTGCCCCAGCCGCCCATCTGCACCATAGACGTCTACATGGTGATGGTCAAATGCTGGATGATTGATGCTGATAGTCGGCCTCGGTTTAAAGAACTCGCTGCAGAGTTCAGCCGCATGGCACGAGACCCTCAGAGATACCTCGTCATACAGGGGGACGATCGCATGAAGCTTCCCAGCCCCAACCACAGTAAGTTCTTCCAGAGTCTTCTCGATGAGGAGGAGCTGGATGACCTGATGGACGCAGAGGAGTACTTGGTTCCTCAGACTTTCAATATCGCTACCTCTTCTTACACATCTTCTTACACAAGACCACCAATGGATACCAGTAGGACACAACTCAAGTGTCGTGAGAGAGTTTTTATCCCAGAAGACGGGATGGGAGCTTGTTCTCATGATACTTCTGGTACAGCGAGTGGCGTCTTCATTCCTATAAGCACACAAGGTGCGGGTCTCGAAGCCCTTGAGGAACAACACTGTAATGGGAGCTTGAAAAAACAGCCCGTGTCTGCTGGAGACGACTGTGACAGCCAGCGCTACAGCGCAGACCCAACTGTGTTTTTCGCAGAAAGGAATCAGAAGGCCACTGGTGAAGATGGTTACATGAGCCCTATGAACAAATCAGCCTCAGACCATCTTAGCCCTGTCGAGGAGAATCCTTTCGTAAACCAGcggaaaaatggaaatattacTGCACTGGACAACCCGGGTTATCACAGCACCCCTGATAGGAAACTCAAGGGTGAAGATGAATACATCAATGAACCCCTTTACCTCAACAcatacaacaacaacatgaaCCAGGAGATTATGAGGAAAAATGGAGCTTCCATCCCTCTGCAGATGACAACAACAGCCAACACCGCAAGTAGCCACGTTATCCTCCCGACACAAACTGGGAAAGCCCACCACCACGGCCAGGGAACACATGTTCATTTCGCCGTTCCACCTGTTCAGCCCCCCCAGACAAGATCGATGAGCCAAAATGGCCAGCATTCCCAGTCGCCACACGGTGCTGAATCCAATTCCTCCAGCATGTCTGGCAATCCCTCCTTATTAACCCAAATCTCCCTCGTCAGCCAACAGATCCAACCTTGTCTGGCAAGTCAGTCTGGCTCTACAACTCATCCGGCTCAAGTGTCGAAATCTGCAGTCACCGGTAAAAGTATATCCGGCCTTCCCGGCCACCTTGTCTATCCAGGTAACATGCTTCAAACGGGTCATTCTGGTACTGTAATGGTCGACAGAAAGTCAAAGAAGAATTTTGATAATCCTGACTACTGGCAGCATAGTCTACCGCCCAAGGTGACCCAACAGAACCCTCAAGATCCAACTCAAGTGTGCAAAAGCAAACATCTTTACAGGCACAGCATCCGAAGTCGCATCGCCATGGCTGACAACCCTGAATATCTTTCCGAGTTTAACAAGAGGCCAGGAACGGTTCTGCCACCTCCACCTTACCGGCACAGGAATACGGTAGTGTAATGCCGCAGTTCTAGAGAGCCAGATTCTTCCACCAGCACCGTATGCTAATTTGGAATTACCGAAGAACAGGAAAAGTCCCAACTTCAGGAATTACTGAAGGAGACTTATCAGACTTTACAAGGAAAACCGATCAACCAAAGTGCCTCTAAATTATTCCAAAAGCTATTCCATCTTTTCTATTCCAACAAATCAGAATGTATTTAGATGTACATTCTTTAAAGGGAAAGTGTAAACCAAAAATGGGTATTCTGTATCATTTACCTTCCCTCATGTTACTCCAAACTTAAAGCACTTTCAaactcaaatgaaaatattttcattttcgaATCCTGATTGATATGTCTCTCCATTGAAGGTCCATTgcaccaagaaaaaaaattaaaattttgattagaccagaataaaaatgacactttttttcagtgtacaacaaaactttcaaaaagttcataaaataaatccaTATGAATTGTTTTTTGTCACTTGTCAAGCAAGTATGGTTAATCTTCCATTTACCGTATTTGATAAGCTCTATGTGCGCGCATTGCTcagtgtttatatatgaaaaaatgccTAAATTGCATAATCACATTAAGCAATTGTGTCTCTGCAGAAGATTTAGATTAAACCTCTTTATACAATCTAAAAATGCTGGATTAAATACAGGTTAAATGTTTAACCCAATCTTCTGGGCAGTATCCCAACTGCTGGATTTGTCCGTATTTTAGCCAGCACCGGTttgtatttaacccagcatttttggatttgttttatgAACTCTTTAAGTTTTGGTGAAGGGACAAAATATCTCagaacttatttaaaatgtcttatttagTGTTTGAAATTTCAAGTCATGTTTGCTTTTAAGggttaaatgatgaaagaatattcatttttgttcaaacgAACTCTTTAATTCTCACCTCTGACTAACTCTCCTACAGTTTGGTGCGTCATAACTTTGTGGAAACTGGGAAGGTAAGGAAAATCAAGAATTCACACattctagtgttttttttattcgaaAGGAAATGGACTTGTAATGTTTCTTTGTGGTTTTGACCAGATGTCTTTTTGACCACTTCCTATTCATCTTGTATTCTTGCTGTTGATGCCGTAAGCTATATTCTCTTCCATTTTCTTGACTGAAGGACAAGGATTCGTTACGAATCTAGGATCGCCCCTTAAGAAAACGGGGTTACCGTAACTCTTATGTGAATGAGACAATGACGTGGATTGTAAATTGGTGCATCTTCTTGTACTGTAGTGGATTTCTTAATGGACTACACTGCtatttattttcagtcattgcgctctttttcatgttttttaaagacCTTACTAATTTCCCCCAGTTTTGTACTCAGATGTACAAACAAATCTGATACAGGCAGAGAAAGAGCACATGGCTAGCCATACAGCTTCTTGAGCTAACGGGAAATAAGTGCCTTCCTCAGTGGCACAAAAGCATCGGTGGATGTGCCAATGGAGTGATTTGACCTGGAATCTTTAACTGTTGTAAATATACGTGAAACTGATTTGAATATTTACTGAGCCACCCATGTGCAAACAGACTCACCCACAGCCGGGGAACCATGTATTGAACATGTTGTTGTATTTAATTCATCTAGTAATGAATTTAACGGCAAGGTCGCTATATTCTGGAAGGCAATATTACAGGTGATGGAGGGCACAATACAAACTCAAATAAACTACTGATCTCCAATGGAGAATTTTTCAAAGTACTGTGACAGAAAATACTTTTGTCTGAAATGTATCCTGCTCTCAGTGAGAGTGTGACCGTATTGTGGCCAGGGCGAAAGTGTTCATATGTTTTATAAACTGTTAATGGGCGTTTGTCATTAATTATGTCAGAGTGTCATAGCAGATAAGAAGTTGTGACTGTGCAAATTTGGTCCTAAACATACCATGCTGAAATTATGAGGCTTTGATTTGCTTTTGACTGAACCGCCATGAGAGATGTAGCTAGATTTGTTTggcttttctgttttgttcttttctttgccttgtacttttgtttgttttggggcTATTCCAAAAGATGCATCTCATCCCTGTTGTAATTCTATTTGATGGAATGACACAATAAAGGTCTTGTTTGagattttaaaattgttcttATGTTCCTAGAGTCTGAGATGTGGAggtcttttgttgttgttgtatggTACAAGCACCAGCTTGTTCACTACACTTTTCAGCTGCAATCCATCATGTCTGAACTTGCCCTTACAAACAATTACTATGGGGCTATGGAATTGGATTTGCCAGCAAGTTACATTCATGTGTTTGCTGCTTcctctgctttttgttttatttatttgttgttttaactgATAATTAGTAAGTTATTGGAATGGAAACTGatctttaattaaagaaaaagttcaccccccccaaaaaaaatgctgacaagttactcatcatcaggttgtccaagatgtagatgattttgtttcttttgtgaaaattaGTACTGCATCACTTATTCACCTATGGATCCTCTAAAGTAAACGGGTACCATCGGTAATCCACtacagtccatcaattaacatcatgaagtgaaaagctgtgtgtttgtaaaaaacaaatgacCCATCCAATTATTGTGAGCTgctttgacggcacccattcactgcggatGATCCATTTATTGAGAAAGTggtgtaatgctacatttctccaaatctattccAATAAAGTAAGCTTTCAACACTTTtccagttttgggtgaactatttctttaacgcCCAAcatctaaaaatgatttatattggTTGTTTATTCAGTAATTTCATTCATCAAGCAGATTGTCCAGGctgcttttttaattgtaaactCTCGAGATTTACACCTACCACATTAAGACTTTAGATgactatttgtatttatttagttatgtattattattattattttaatcacagGAGCAGGCTGGTGAAATGCATTTCCATGAAGGCAACATTGCAGTACGTTATGGTACAAATCCAAGCAGTCATATGCACAACTGACGTACAATAAAAACTGTAGAATCAGtagttctaaataaataattaactcaTTCTGTTTCAATTTCCCTCAGTTTGacttgaatttaaaaacatcattgtCTGTCTCCTCTTTCATTCCTGTCTCTTTTGTTCATAAGACAAGGAAGTAGAGTATTTTAGCTCACTGATCTCTGCGCATGGAGACTTTATTCCAGCTAGGCAGAGGCAGTAAATGAATCAAACTGTCAGCTCATGGAGGTTTACCTCAACCCATGTTGTTCCTCTCTAAGAATAAATGCCTGTGGatgttt

Function

symbol description
erbb4a Predicted to enable epidermal growth factor receptor binding activity and transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within generation of neurons. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in basal plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in heart and nervous system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4).
erbb4 Enables several functions, including epidermal growth factor receptor binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including positive regulation of phosphorylation; positive regulation of signal transduction; and protein phosphorylation. Located in basolateral plasma membrane; mitochondrion; and nucleus. Part of receptor complex. Implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Biomarker of carcinoma (multiple); ductal carcinoma in situ; reproductive organ cancer (multiple); and urinary bladder cancer.

NR:

description
PREDICTED: receptor tyrosine-protein kinase erbB-4-like

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0016020 membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0004714 transmembrane receptor protein tyrosine kinase activity molecular_function

KEGG:

id description
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043240427.1 True 7836 mRNA 0.44 27 5157979 5294440

Neighbor

gene id symbol gene type direction distance location
ube2f ube2f,LOC107725407,LOC107556276,LOC107674019,LOC107707607,LOC107566887 coding upstream 1623 5149028 ~ 5156356 (+)
si:ch211-93g23.2 si:ch211-93g23.2,LOC107725372,LOC107674017,LOC107556277 coding upstream 9089 5145908 ~ 5148890 (+)
fastkd2 LOC107673994 coding upstream 191059 4960324 ~ 4966920 (+)
retreg2 fam134a,LOC107706836,LOC107676053,LOC107556270,LOC107750069,LOC107673992 coding upstream 202936 4945839 ~ 4955043 (+)
cnppd1 cnppd1,LOC107706838,LOC107676054,LOC107750058,LOC107549439,LOC107556284 coding upstream 220300 4932455 ~ 4937679 (+)
si:ch73-383l1.1 erbb4a,erbb4,LOC107705456,LOC108440448,LOC107674013,LOC107702505,LOC107707608,LOC107667809 coding downstream 145625 5440065 ~ 5562873 (+)
lancl1 lancl1,LOC107564761,LOC107702553,LOC107590692 coding downstream 299202 5593642 ~ 5600055 (+)
mylz3 mylz3,LOC107725378,LOC107564772,LOC107701775,LOC107702554,LOC107705457 coding downstream 309267 5603707 ~ 5607415 (+)
LOC122347193 pcnp,LOC107564735,LOC107590694,LOC107702552 coding downstream 313889 5608329 ~ 5610739 (+)
en1b eng1b,en1,LOC107705463,LOC107702516 coding downstream 373957 5668397 ~ 5672318 (+)
G1036 NA non-coding upstream 998 5156722 ~ 5156981 (+)
LOC122346173 NA non-coding upstream 19125 5127490 ~ 5138854 (+)
G1016 NA non-coding upstream 56657 5038720 ~ 5101322 (+)
G948 NA non-coding upstream 180065 4977422 ~ 4977914 (+)
LOC122346140 NA non-coding upstream 239184 4896504 ~ 4918795 (+)
LOC122344626 NA non-coding downstream 110172 5404612 ~ 5408298 (+)
G1064 mxa,mx1,LOC107702551 non-coding downstream 298774 5593214 ~ 5626276 (+)
G1061 NA non-coding downstream 319947 5614387 ~ 5622881 (+)
G1060 NA non-coding downstream 321280 5615720 ~ 5623944 (+)
G1086 NA non-coding downstream 379932 5674372 ~ 5674683 (+)
hecw2b hecw2,LOC107674007,LOC107676038,LOC108258347,LOC107706834 other upstream 132065 4979125 ~ 5025914 (+)
gtf3c3 gtf3c3,LOC107706835,LOC107750061 other upstream 180716 4967186 ~ 4977263 (+)
prkag3a prkag3a,LOC107750059,LOC107673997,LOC107676055 other upstream 213138 4938181 ~ 4944841 (+)
G826 NA other upstream 799683 4358007 ~ 4358296 (+)
G824 NA other upstream 800719 4356698 ~ 4357260 (+)
G1168 LOC107725347,LOC107565259,LOC107701771 other downstream 585020 5879460 ~ 5881134 (+)
G1183 actb,actb1,LOC102799139,LOC107581721,LOC103039558 other downstream 762964 6057404 ~ 6087655 (+)
G1318 NA other downstream 991418 6285858 ~ 6287198 (+)
G1414 NA other downstream 1239062 6533502 ~ 6536957 (+)
G1447 fga,LOC107692636,LOC107565125,LOC107714149,LOC107758872,LOC108439170 other downstream 1417195 6711635 ~ 6845548 (+)

Expression


Co-expression Network