XLOC_010657 (il6r)


Basic Information

Item Value
gene id XLOC_010657
gene name il6r
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 22177254 ~ 22194400 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020864
GCGTTAGATGTTGGGTCACCTAGTTCTAAATCTGCTCTGTAGTAATAAACCCAACCGCAAACTGAAATAGTTTGTTTCTCGGTCTTTGCCTTGTCAAATAGGAACTTGTTTGTCTTTGTGGGTCGCAGTGTCGCAAGAGcggatttgttaaaaaaaaactgatagtgTAAAGTGCGTGAGAAGAGGAAAGGGTTGCAGTTTTCTGGCTCTCATAAACAAACGAGCTCCGGATCGAAATCTTGTCTTGAGGCAGCTGTCTAAATCAAGACATCTGTTTTGAGTAGGTACAGTGTTGGTTTAGCCAACCTGTTTCACCTTAGTTTTGTGATGtgatgaaaatgtaaattaatactgATCATGTTAACATTATGACACGTTATACCCATATTGTGTATTTTGGAGGCTAATTATATTGTTTGGAAGTGGATTTATAATGTGGACCCGATCTACACGCATGTTTCTCCTCGCTGTGTTTGCTGCGGTTAAAGTTCAGTCTGCCCGAGCTGAAGCTGAACTGTGTCCTCGACAAGATCCTCCTTCTGGAGTTTTGGTCTTGAATTTGGGAAGTAATGTTGTCCTTGGCTGCAGAGGTGACGTTACAGTGGACAATGTGTCGTTGGCTTCAGCCAGAGTcatgaataaaaaatacacacacaagcagaaaGAAGACATCACTGCCAGCTGGACATCCCAGAGACACAAACATCCTTCTACACAATTAGCTAATATAAAGGGAGATGTGCCAACTACAACATACCAAAATATGATGTCTGCTATATACTCTAAAACTGAAGTGGGCACAACTGTCACCGTTAAACCATCTATAACCACCAGAAAGGAGCAGAACACTTCTCAACGTGTTTTGCGTGCTGTCAGTCAAACACCTGGAGAGGAAGAAGAGACGTTTGGTATCACACAGTGGAGCGATTTTGATGAAGATGATTATGAGGACTATGATTATGAAGAGGAGCGATCCAGGGTGACACGGGGAATCAAAAAACAAACACGCTGGACTTTAAATGGAAGACAGGTGCATGCCGGAGTGGAAAGAGGAGGAATTTTGAGACGGCCACATCTCAGCTGGGCAGATGCTGGAAATTACAGTTGCTACAGAGGAGAGAGACTCATTTCCACATTCAGAATCAGTGTAGGGGCACCCCCCGAGCGTTCAGCTGTCTTATGCAACATGAAGTCTCATACTAGTAAGGTCCGCTGTGAATGGACGTCCAAACAACCGGTAATTCCACGGCCAGTGTGTTACCTTCTTCTTAATAGAAGatttttaaaaaacaccATTCATGTGAACTGTTCTTTCTCCCGGTCCCGCTGTTGGTGTGCTTTCTTTGTGAAGGAGGAGTACCTTAGGGATCTCCATAGGGCACAAATATGTGTGTCTAACATAGCAGGCAGTGCAATGAGCCCTGTACTCAACTTTAACCCACATGACACCCTAAGGCCAGACCCACCAAGCAGAGTTCTGGTGAGTGCAGTTGAGGGCCTGAAGCATGTGCTTAAAGTATCCTGGTCTTATCCCAGTTCCTGGAAGAATAGATTTTATGTCCTGCAGTTCCATCTGAGATACCGACCACAATTTGCAGAGCAGTACCAGTTTGGGGAGATATCTGACAAGATGGAGAGACGACTGTCATGGATGATTTATGATGCTCTACCAGACACTGTATATGAAGTGCAGCTTAAGGCCAAAGATGAGTTTGATGGTAGCTGGAGTGACTGGACAGAACCTGTCTTTGCAGTCACATGGTCAGCTCCTGAGACAACTACTGCCACTGAGACCATTACTTTTGAACCAAATGAGGTGCTTTATGAAGGCTCAGGAGGATTTGGAGAAGAGCCTGGTGTAGACTCAGTGGTAGTAGCTGGAGATGCTGATACCGAATATGCTACAGTCTGGCTGTATGTGTCTTGTGCTTTTGGGCTGTGTTTTTTTGTAATCACCGTGCTTACTGTCTATTTTCTCAGGAATAGGACTCATTTGATTGCTAAAATAGGGAAACAAACTATGCCGTTTACTTCCCTCCTTCGTTCCTCTCAGCCTCTGTCTGCTCCTGCTGCCTCTGAACAGCTTCCCGAGGAGGGGAAGTCACTTATGTCTCCTCCCAAACACAACCAGCAACACTTCCTTCCTGCTCAGCCAGAGGAGCAGGATGCCATTCATCTGCATAACATCGATTATTTTCTGTCTCCAGGAGCCGAAGGTGTGCCATTgacaataaacagaaatgaataaacaaatgaaacccCGCAGTGGGTCACACACTGTTTCATGTGATAGAAAAACAGCATTATTATGTTGAAAAATCAACTTGGAGTGTCATATCCTAGGTTGGGTTTTcatgtcagatttttttctgaCTTTCAAAACCATTTGTAATTACGGATTTTTAAAACAAGCCTTCTATAGAAaactttttacaaatatttccttaGACAACCCACCATTTGTTGACCATGGCAGTCTTCCATGTGAAGCTAAAgcacttttttattaaatagttttgaaTAAATGCCTGTTAACATCAAATATGATAGCTAAGATGACTGGTTTTAAATTATAAGTTAAAGAAATACACAGTTTTTGTTTATCTGATGAATGATATAAACTTTGACAGCCAGTCTTATTCAAGATTACTGTAAAGATCTTGGGCATTTCAAGTCGTAGATGTAAAAACTGCAGTGTGCACTTATAATAGACAGAATATTTTCATGGTTTGGTGAGATGCAAATACTGTTATCGGTATTGTTCTTGATTTAACAGgcttttaagggatagttcacacaaaactaaGAGAAAATTTCTTCACAGTTTACTCACAAACAAACTAACCGCTATTGGAATCCAGAGTAGGAACAACACAAAATGCAATGGATGTCAATGACTGCTGTTTTCCATAATTCTAgagtaaaataaaacttaaacaggtttaatCTCTTTAAGAGTGTCTGCTAAATGTTTGATGTTCGTTTGAATATGATCTTTCATTCAACATTAGTTATTTTGACTTGCTGACTTATGTTGACTGTTATtctgtttaaatgtgtgtaatttgaCCTGTAAAAGTGTTTTGGTCTCACAGTCGTTTTTACAGTTTATGAAAATGTATGCATTGTGATTGTAAAATTGTAGTCACTCAgacaaaaaagcatttttttttcaaactaaaattaTGTCaccatttttaccatgttttatttTGAGTTTGTACTAATTGAAAATGTGAATTACAAAGGGAAAAGTTACAAGGGGAAAGTTCACCCATTATTATAATTCTGACATTGTTTACTCTCCTTCCTCTTGTTCCAAaccttgagttttttttctttcttttttattcaaaAGAATATACAGTACTTTGAGGAATGTTGAAAACTTGTAGCTATATATGACATACTGTATAGTATATTTTCCTACCGTGGAAGCAAGTGTCAACCTGATACCAATATGGAGGGGGAAGGGTTAGAAATATTTGTTTAAACTGTccctttttttaataatgaatgagAACTGGGGTTTATACTTtcatgggtaacactttaaacgttaatttctttattattcagtttaacatttactaatgcatattaaaatcaaatttaaTTCATTAGTTATTTCACTGAGTTAAAATGAACTAACattaaacaactttattttcaataACTAATGTAAACAAGGAGGGATGCTGTAATGTATTGTTAATGGTTGGTtaatgttaaatacattaacactaaTACCACCATATTGTAAAGAGTTGCCCTTTTCCTGATTGAATGTATGTTTTTCtgctaaatgtgttaaatcataTTTCAGTTTGTCTgtacattgctttttaaaatagatATTGTTCTAAAGCATCTTCATAAATACTAgtgaaaaaaaccttgagaagaCAATGGACAGACAAGTCCCTAAGATGGTATGTGGGATGTTTTGTTaggaaaataattgtttaaaaatacagtatacTGTAAAAACATGCTCAATTTGAT
>TCONS_00020865
GGTGACGTTACAGTGGACAATGTGTCGTTGGCTTCAGCCAGAGTcatgaataaaaaatacacacacaagcagaaaGAAGACATCACTGCCAGCTGGACATCCCAGAGACACAAACATCCTTCTACACAATTAGCTAATATAAAGGGAGATGTGCCAACTACAACATACCAAAATATGATGTCTGCTATATACTCTAAAACTGAAGTGGGCACAACTGTCACCGTTAAACCATCTATAACCACCAGAAAGGAGCAGAACACTTCTCAACGTGTTTTGCGTGCTGTCAGTCAAACACCTGGAGAGGAAGAAGAGACGTTTGGTATCACACAGTGGAGCGATTTTGATGAAGATGATTATGAGGACTATGATTATGAAGAGGAGCGATCCAGGGTGACACGGGGAATCAAAAAACAAACACGCTGGACTTTAAATGGAAGACAGGTGCATGCCGGAGTGGAAAGAGGAGGAATTTTGAGACGGCCACATCTCAGCTGGGCAGATGCTGGAAATTACAGTTGCTACAGAGGAGAGAGACTCATTTCCACATTCAGAATCAGTGTAGGGGCACCCCCCGAGCGTTCAGCTGTCTTATGCAACATGAAGTCTCATACTAGTAAGGTCCGCTGTGAATGGACGTCCAAACAACCGGTAATTCCACGGCCAGTGTGTTACCTTCTTCTTAATAGAAGatttttaaaaaacaccATTCATGTGAACTGTTCTTTCTCCCGGTCCCGCTGTTGGTGTGCTTTCTTTGTGAAGGAGGAGTACCTTAGGGATCTCCATAGGGCACAAATATGTGTGTCTAACATAGCAGGCAGTGCAATGAGCCCTGTACTCAACTTTAACCCACATGACACCCTAAGGCCAGACCCACCAAGCAGAGTTCTGGTGAGTGCAGTTGAGGGCCTGAAGCATGTGCTTAAAGTATCCTGGTCTTATCCCAGTTCCTGGAAGAATAGATTTTATGTCCTGCAGTTCCATCTGAGATACCGACCACAATTTGCAGAGCAGTACCAGTTTGGGGAGATATCTGACAAGATGGAGAGACGACTGTCATGGATGATTTATGATGCTCTACCAGACACTGTATATGAAGTGCAGCTTAAGGCCAAAGATGAGTTTGATGGTAGCTGGAGTGACTGGACAGAACCTGTCTTTGCAGTCACATGGTCAGCTCCTGAGACAACTACTGCCACTGAGACCATTACTTTTGAACCAAATGAGGTGCTTTATGAAGGCTCAGGAGGATTTGGAGAAGAGCCTGGTGTAGACTCAGTGGTAGTAGCTGGAGATGCTGATACCGAATATGCTACAGTCTGGCTGTATGTGTCTTGTGCTTTTGGGCTGTGTTTTTTTGTAATCACCGTGCTTACTGTCTATTTTCTCAGGAATAGGACTCATTTGATTGCTAAAATAGGGAAACAAACTATGCCGTTTACTTCCCTCCTTCGTTCCTCTCAGCCTCTGTCTGCTCCTGCTGCCTCTGAACAGCTTCCCGAGGAGGGGAAGTCACTTATGTCTCCTCCCAAACACAACCAGCAACACTTCCTTCCTGCTCAGCCAGAGGAGCAGGATGCCATTCATCTGCATAACATCGATTATTTTCTGTCTCCAGGAGCCGAAGGTGTGCCATTgacaataaacagaaatgaataaacaaatgaaacccCGCAGTGGGTCACACACTGTTTCATGTGATAGAAAAACAGCATTATTATGTTGAAAAATCAACTTGGAGTGTCATATCCTAGGTTGGGTTTTcatgtcagatttttttctgaCTTTCAAAACCATTTGTAATTACGGATTTTTAAAACAAGCCTTCTATAGAAaactttttacaaatatttccttaGACAACCCACCATTTGTTGACCATGGCAGTCTTCCATGTGAAGCTAAAgcacttttttattaaatagttttgaaTAAATGCCTGTTAACATCAAATATGATAGCTAAGATGACTGGTTTTAAATTATAAGTTAAAGAAATACACAGTTTTTGTTTATCTGATGAATGATATAAACTTTGACAGCCAGTCTTATTCAAGATTACTGTAAAGATCTTGGGCATTTCAAGTCGTAGATGTAAAAACTGCAGTGTGCACTTATAATAGACAGAATATTTTCATGGTTTGGTGAGATGCAAATACTGTTATCGGTATTGTTCTTGATTTAACAGgcttttaagggatagttcacacaaaactaaGAGAAAATTTCTTCACAGTTTACTCACAAACAAACTAACCGCTATTGGAATCCAGAGTAGGAACAACACAAAATGCAATGGATGTCAATGACTGCTGTTTTCCATAATTCTAgagtaaaataaaacttaaacaggtttaatCTCTTTAAGAGTGTCTGCTAAATGTTTGATGTTCGTTTGAATATGATCTTTCATTCAACATTAGTTATTTTGACTTGCTGACTTATGTTGACTGTTATtctgtttaaatgtgtgtaatttgaCCTGTAAAAGTGTTTTGGTCTCACAGTCGTTTTTACAGTTTATGAAAATGTATGCATTGTGATTGTAAAATTGTA

Function

symbol description
il6r Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including epidermis; immune system; lateral line; liver; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).

GO:

id name namespace
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0009897 external side of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0004896 cytokine receptor activity molecular_function
GO:0019955 cytokine binding molecular_function

KEGG:

id description
ko04630 JAK-STAT signaling pathway
ko04066 HIF-1 signaling pathway
ko04151 PI3K-Akt signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04061 Viral protein interaction with cytokine and cytokine receptor
ko04640 Hematopoietic cell lineage
ko04659 Th17 cell differentiation
ko05200 Pathways in cancer
ko05171 Coronavirus disease - COVID-19
ko05163 Human cytomegalovirus infection
ko04932 Non-alcoholic fatty liver disease
ko01521 EGFR tyrosine kinase inhibitor resistance
ko04050 Cytokine receptors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-080107-7 Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including epidermis; immune system; lateral line; liver; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).

Ensembl:

ensembl_id ENSDARG00000104474

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020864 False 4005 mRNA 0.38 10 22177254 22194400
TCONS_00020865 True 2555 mRNA 0.41 9 22178115 22192006

Neighbor

gene id symbol gene type direction distance location
XLOC_010656 CR855277.4 coding downstream 112798 22060569 ~ 22064456 (-)
XLOC_010655 si:dkey-71b5.3 coding downstream 154798 22015648 ~ 22022456 (-)
XLOC_010654 NA coding downstream 164934 22009119 ~ 22012320 (-)
XLOC_010652 si:dkey-71b5.7 coding downstream 170258 21946091 ~ 22006996 (-)
XLOC_010653 NA coding downstream 186916 21960125 ~ 21990338 (-)
XLOC_010658 LO017682.1 coding upstream 5110 22199510 ~ 22225295 (-)
XLOC_010659 atp8b2 coding upstream 42561 22236961 ~ 22251457 (-)
XLOC_010660 aqp10a coding upstream 94377 22288777 ~ 22294265 (-)
XLOC_010661 si:dkey-92i15.4 coding upstream 101262 22295662 ~ 22303130 (-)
XLOC_010662 NA coding upstream 139892 22334292 ~ 22335517 (-)
XLOC_010626 CR392024.2 misc downstream 1282079 20895112 ~ 20895175 (-)
XLOC_010649 NA non-coding downstream 320903 21855296 ~ 21856351 (-)
XLOC_010647 NA non-coding downstream 340686 21836180 ~ 21836568 (-)
XLOC_010663 NA non-coding upstream 168072 22362472 ~ 22368440 (-)
XLOC_010666 NA non-coding upstream 317582 22511982 ~ 22515521 (-)
XLOC_010675 NA non-coding upstream 700276 22894676 ~ 22989262 (-)
XLOC_010676 NA non-coding upstream 822557 23016957 ~ 23019603 (-)

Expression


Co-expression Network