XLOC_012612 (impdh1a)


Basic Information

Item Value
gene id XLOC_012612
gene name impdh1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 8805575 ~ 8842818 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025234
GCATGGGCATGGGCATGAGACGGCAGCCCAGCGCTACAGTGCCACACGGATACAGGCGGGATATGAGCCAGAGAGCATGGCTGATTACCTGATCAGCGGGGGAACAGGGTATGTTCCAGAGGATGGACTCACTGCCCAGCAACTCTTTGCCATCGGTGATGGTCTCACATACAAtgatttcctgatACTGCCTGGGTTCATTGACTTCATATCGGATGAAGTGGATTTGACCTCTGCCCTGACCCGGAAAATAACCCTGA
>TCONS_00025235
ACTTCAGTTCACGCTGTTGTCggtctgtaaacacacacagactgcgCGTCTCACCACGAGCCCGGAGACCCTTCATCCACAGCGGCTTTGCCCTTCAGAGCTCTGCTGCGCGGAAGGAGAGACTAGTGAACCCCGCGTTGATCCGTCACGctctttaatataaaaatgtagcaGTCATCATGTGAGCTACTGTACATGGGGGCGAATATTCAGCAGAAGGAAGTGTGTTCCGAAAGAGAAAGTAACTCGAGACTCATGGCTGATTACCTGATCAGCGGGGGAACAGGGTATGTTCCAGAGGATGGACTCACTGCCCAGCAACTCTTTGCCATCGGTGATGGTCTCACATACAAtgatttcctgatACTGCCTGGGTTCATTGACTTCATATCGGATGAAGTGGATTTGACCTCTGCCCTGACCCGGAAAATAACCCTGAAGACGCCACTCATTTCCTCTCCAATGGACACAGTCACAGAGTCCTCAATGGCCATTGCTATGGCTCTCATGGGAGGAATTGGAATTATTCATCACAACTGCACGCCTGAGTTTCAGGCTAACGAGGTCCGGAAAGTTAAGAAATTCGAGCAGGGCTTCATTACAGACCCTGTAGTGATGAGTCCACGACACACAGTAGGAGATGTGTTTGAAGCGAAGGTACGGCACGGTTTCTCTGGCATCCCAGTTACTGAAACTGGAAAGATGGGCAGCAAGCTGGTGGGCATTGTTACGTCACGAGACATCGACTTCCTGTCAGAAAAAGACTATGATAGGCCACTGGAGGAGTCAATGACAAAACGAGAAGATTTAGTGGTTGCTCCAGCTGGTGTAACATTAAAAGAGGCAAATGACATCTTACAGCGCAGTAAAAAAGgtAAACTGCCTATAGTGAATGACAGTGATGAGCTTGTTGCAATAATCGCTCGTACCGATTTGAAGAAGAACCGAGATTATCCTCTGGCCTCCAAAGACTCCCGCAAACAGCTCCTGTGCGGCGCCGCCATCGGCACCCGAGAGGACGACAAGTACCGGCTAGATCTGCTCATGCAGGCTGGAGTGGACGTGATCGTTCTGGACTCTTCTCAGGGCAACTCAGTGTTTCAGATCAGTATGATCAACTACATCAAACAGAAGTACCCAGAACTGCAGGTGGTTGGAGGAAACGTGGTGACTGCAGCTCAAGCAAAGAATCTTATAGATGCTGGTGTTGATGCTTTAAGAGTGGGCATGGGCTGTGGATCCATCTGCATCACACAGGAAGTGATGGCGTGTGGGAGACCGCAGGGCACATCTGTATATAAAGTGGCTGAATACGCCCGGCGTTTTGGGGTCCCAGTCATTGCCGACGGTGGCATCCAGACAGTGGGTCACGTCGTTAAAGCCCTGGCACTGGGAGCgtccacagTAATGATGGGCTCATTGTTAGCCGCCACCACAGAAGCGCCCGGTGAGTATTTCTTCTCAGATGGAGTTCGGCTCAAGAAATACCGTGGTATGGGCTCTTTAGACGCCATGGAGAAAAACAACAGCAGTCAGAAACGCTACTTCAGtgaaGGTGATAAGGTGAAGGTGGCTCAGGGAGTCTCTGGCTCAGTTCAGGATAAAGGATCGATACACAAGTTTGTTCCATACCTCATTGCAGGAATTCAACACGGCTGTCAGGATATCGGTGCAAAGAGTCTGTCCATTCTGCGATCGATGATGTACTCTGGAGAGCTGAAGTTCGAGAAGAGGACCATGTCTGCTCAGGTTGAGGGTGGAGTTCATGGACTGCATTCATATTCTTTTTTGCCATTTACGAGAAACGGTTATATTGAGCCTGGCAGCAGAGGGCACCCAAGAGCTGGACCTAATGTCCCGTCACCGGCCGTCACTAAACACAGCAGctaaaaaaaaagccatttctACACAACCCTCAATCCTTTGTCCTTCTTCCTGATGGCTCTCAAATCCTTGGTAAACTTAAAAAACACTTTATTGCAAGCCATCATTGGGACTAAATAACCTATGGAGCTTTTGTTTCATAgctgcatttttgttttgttcggGCTTCCCTAAAAAAATGTAGACTATGAATGTACTCTGAAATATGAAGATCCTatacgtgtgtgtatgtgaaacAGAGTGTATCTTATATATTTGTGGTATACAGGGTATGTTTAGTCTGTCTTGTTCCAAAGATCCTAATTAAAAACGTCTGTTGGTTTAATAGCAATAATATATGTTGAGGTGAATCATGTGCACCACATGTGTAAGTGTTATGAGTTCAGTTCTATTGAAATCTATTATGAAATGAATTAGTTTTCTTGAATACGTTTGCAGGCTGCTTGCTGTTTAATCAGATCGCACTAGAACCATGACCGGATAATGAGTATCAGCCTTAAAATCAGGGAGTTTGTACTGTTACTCGCCTTATGCTAgtcaataatgtatttattagacAGTAGAGGCGCTCATTTCTCAACGTTTATTTATTCGTTTCACACACTTGCATCATCTTAGAAGGATTTACATATATCaaacattttacagtataaaaaaattGCGAGATTTTACAAGGTCAGAAGTGAAGGAGAGTCGTACGCATTTGCTGTGAAAGTGACACTGAGCTCTATTTTGTAGTTTGCACAGATTGTTGGATTGTTATTCTGAATATAATGCAGTTTATAGAATAAAGAATGAGTTTTTATA
>TCONS_00025236
TGATGGCGTGTGGGAGACCGCAGGGCACATCTGTATATAAAGTGGCTGAATACGCCCGGCGTTTTGGGGTCCCAGTCATTGCCGACGGTGGCATCCAGACAGTGGGTCACGTCGTTAAAGCCCTGGCACTGGGAGCgtccacagTAATGATGGGCTCATTGTTAGCCGCCACCACAGAAGCGCCCGGTGAGTATTTCTTCTCAGATGGAGTTCGGCTCAAGAAATACCGTGGTATGGGCTCTTTAGACGCCATGGAGAAAAACAACAGCAGTCAGAAACGCTACTTCAGtgaaGGTGATAAGGTGAAGGTGGCTCAGGGAGTCTCTGGCTCAGTTCAGGATAAAGGATCGATACACAAGTTTGTTCCATACCTCATTGCAGGAATTCAACACGGCTGTCAGGATATCGGTGCAAAGAGTCTGTCCATTCTGCGATCGATGATGTACTCTGGAGAGCTGAAGTTCGAGAAGAGGACCATGTCTGCTCAGGTTGAGGGTGGAGTTCATGGACTGCATTCTTACGAGAAACGGTTATATTGAGCCTGGCAGCAGAGGGCACCCAAGAGCTGGACCTAATGTCCCGTCACCGGCCGTCACTAAACACAGCAGctaaaaaaaaagccatttctACACAACCCTCAATCCTTTGTCCTTCTTCCTGATGGCTCTCAAATCCTTGGTAAACTTAAAAAACACTTTATTGCAAGCCATCATTGGGACTAAATAACCTATGGAGCTTTTGTTTCATAgctgcatttttgttttgttcggGCTTCCCTAAAAAA

Function

symbol description
impdh1a Predicted to enable IMP dehydrogenase activity. Acts upstream of or within developmental pigmentation and eye development. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in brain; digestive system; heart; muscle; and sensory system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1).

GO:

id name namespace
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0006177 GMP biosynthetic process biological_process
GO:0006183 GTP biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0048066 developmental pigmentation biological_process
GO:0001654 eye development biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003938 IMP dehydrogenase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040704-15 Predicted to enable IMP dehydrogenase activity. Acts upstream of or within developmental pigmentation and eye development. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in brain; digestive system; heart; muscle; and sensory system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1).

Ensembl:

ensembl_id ENSDARG00000042336

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025234 False 260 mRNA 0.53 4 8805575 8825266
TCONS_00025235 False 2691 mRNA 0.45 16 8812549 8842818
TCONS_00025236 True 784 mRNA 0.49 5 8833251 8842189

Neighbor

gene id symbol gene type direction distance location
XLOC_012611 prpf18 coding upstream 397057 8402129 ~ 8408518 (+)
XLOC_012610 BX248392.1 coding upstream 408250 8397209 ~ 8397325 (+)
XLOC_012609 BX276107.1 coding upstream 438009 8339596 ~ 8367566 (+)
XLOC_012608 chkb coding upstream 466629 8320165 ~ 8338946 (+)
XLOC_012607 arsa coding upstream 562037 8231138 ~ 8243538 (+)
XLOC_012613 CT025776.1 coding downstream 47070 8889888 ~ 8892797 (+)
XLOC_012614 si:dkey-5i3.5 coding downstream 59028 8901846 ~ 8909935 (+)
XLOC_012615 tmem243a coding downstream 69295 8912113 ~ 8916000 (+)
XLOC_012616 ELAPOR2 coding downstream 74948 8917766 ~ 8955573 (+)
XLOC_012617 CT025888.1 coding downstream 268998 9111816 ~ 9111932 (+)
XLOC_012606 CABZ01052527.1 non-coding upstream 702379 8100905 ~ 8103196 (+)
XLOC_012605 CU138508.1 non-coding upstream 806878 7998576 ~ 7998697 (+)
XLOC_012604 LO018377.2 non-coding upstream 922682 7882779 ~ 7882893 (+)
XLOC_012603 LO018377.1 non-coding upstream 930827 7874631 ~ 7874748 (+)
XLOC_012619 CU861648.1 non-coding downstream 381595 9224413 ~ 9224528 (+)
XLOC_012622 BX649551.1 non-coding downstream 765098 9607916 ~ 9608042 (+)
XLOC_012625 CR762488.1 non-coding downstream 968202 9811020 ~ 9811152 (+)

Expression


Co-expression Network