XLOC_012801 (gnao1a)


Basic Information

Item Value
gene id XLOC_012801
gene name gnao1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 22793465 ~ 22975655 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025538
CGATGCCAGCGCTCGCAGTCGCCGCCGCCGCCCAGTAGAGACCTCTCAGCCCGAGGACCGAGCACCACGACCCCGTTACACAGACCGAGAGCGCGCCCCAGAGACTTATGTTCCAGTCCAACGCTGTCTTTTGCGGGATTTAATGCTCTAGCTAGTCGCCGACAGggagagcgagtgtgtgtgtgagagagggataGGGACAGCCTTAGAGAGGGATAAGGAAGAAACACCGAGGATATTTCTCAGCCGGACCGTTTTGGAGATAAAAAAGAGCCGAGGTTCATCTAGCCATGGGATGTACACTGAGCGCAGAGGAAAGAGCGGCTCTGGACAGGAGCAAAGCCATCGAGAAGAACCTCAAAGAAGACGGAATCACTGCTGCTAAAGATGTGAAATTGCTTCTGCTAGGGGCTGGGGAATCTGGGAAAAGTACCATCGTGAAACAGATGAAGATTATCCATGAGGATGGATTCTCCGGTGATGATGTGAAGCAGTACAAGCCGGTGGTCTACAGTAACACCATCCAGTCTCTGGCTGCTATCGTGCGTGCCATGGACACACTGGGCCTGGAGTACGGAGACAAGGAGCGCAAAGCGGATGCTAAGATGGTGTGTGATGTTGTGAGCCGTATGGAGGACACTGAGCCCTATTCTCCAGAGCTGCTGTCTGCCATGATTCGCCTGTGGTCTGACTCGGGCATCCAGGAGTGCTTCAGCCGTGCCCGCGAGTACCAGCTCAATGACTCCGCCCAATAtTACTTAGACAGTTTAGATCGAATCGGAGCTGCAGATTACCAGCCCACAGAGCAGGACATTCTGCGAACTCGAGTGAAGACCACCGGGATTGTAGAAACCCACTTCACCTTCAAGAACCTGCATTTCAGGCTGTTTGATGTGGGAGGTCAGAGGTCGGAGAGGAAGAAATGGATCCACTGCTTTGAGGACGTGACCGCCATTATCTTCTGTGTGGCTCTGAGTGGATACGACCAGGTGCTCCATGAAGACGAGACCACGAATCGCATGCACGAGTCTCTTATGCTGTTCGATTCCATCTGTAACAACAAATTCTTCATTGACACTTCCATCATTCTCTTCCTCAACAAGAAAGACCTGTTCGCTGAAAAGATCAAGAAATCTCCCCTGAGTATCTGTTTCCCTGAATACACAGGTCCAAACACCTACGACGATGCAGCCGCTTACATCCAAGCACAATTTGAAAGCAAGAACCGCTCGCCTAATAAGGAGATCTACTGTCACATGACCTGCGCCACGGATACAGGAAACATCCAGGTGGTGTTCGATGCTGTGACCGACATCATCATCGCCAACAACCTGCGAGGCTGCGGCTTGTACTGAGGCCCGTCCCGTTCCTCTCCAGCCACTTCTTTGGAAATGATTATTATTGAAAATGCAAGTTGGTAAATAATGATAacgataattttaaaaataggcatatacaaatatataaatatattatatatatatatatgaaatgttttTAGTTTGTCTTTCAAAGAGCTGCCAACAGAACTGATTTCTTATAGAAACCCAGCCTTTATGGTTTTAGAACAAAGTTGGGACCTTTTTTTTGTGCGTGTCGTACGTTTCGTTCTCCCCTGTTTTCCACCGTGTCTTTCTCGTTTGAACTAAACAAccctcatttttttgttttgataaatgtctctcttttactatttttttatgttttgtgtcattgtatgtatatttattacaCGGATATCAGTCAGGGGGGATGACCTGTACATGTTTGCCTGGCTACTGAATTTACTTACGCGACAATAGCTAAAATTCACGAGCACTACGGTTCAAGTCAGTTGTAGCGTGTGCCCCCGTCTCTGGATTTTTAATCACCGTAGTACCATTCGACATATCGTAGAGAATGGAAAACACCCAGGATCACTTCTTAACGTCTCAACCCATCCCCGTCACTTCCGTAGGTCAGATCTCTGGCGAGAAAGAGGTCCCTGGGACACTCGACGCCAGTCCAGTGATCGCAAGTGTCATGTCAGTGCCAACCTTCTGAGAATGACGTGTCTGGGAATAGTACTAGAAACACTAGGTCACTGTTATGAGAACTTATTAACATTTGTCTTGTAAGGAACTTTTACTTTTGTATTGttgttgattaatttattaatttatttattgatcatcTATCCCACACACTTCCTTTGTACTTACTACACCTCGTCCATTCTTCTACCTCTCGTCCGCTGTCCCCCTTCCCATTCCTTCTCTTTCCCTGTTTTAGTTGGCTGGGTAATGGAGTCCCCGTCACTGATAGCATGACCCCTTCTTCAGCCTTTGTATAAAGAAACAGCTAACTGCTTCACATAGTGCAAAACGAAAAAAGAAAACTcgaaataaaaagaacaaaaaaa
>TCONS_00025539
GTTCATCTAGCCATGGGATGTACACTGAGCGCAGAGGAAAGAGCGGCTCTGGACAGGAGCAAAGCCATCGAGAAGAACCTCAAAGAAGACGGAATCACTGCTGCTAAAGATGTGAAATTGCTTCTGCTAGGGGCTGGGGAATCTGGGAAAAGTACCATCGTGAAACAGATGAAGATTATCCATGAGGATGGATTCTCCGGTGATGATGTGAAGCAGTACAAGCCGGTGGTCTACAGTAACACCATCCAGTCTCTGGCTGCTATCGTGCGTGCCATGGACACACTGGGCCTGGAGTACGGAGACAAGGAGCGCAAAGCGGATGCTAAGATGGTGTGTGATGTTGTGAGCCGTATGGAGGACACTGAGCCCTATTCTCCAGAGCTGCTGTCTGCCATGATTCGCCTGTGGTCTGACTCGGGCATCCAGGAGTGCTTCAGCCGTGCCCGCGAGTACCAGCTCAATGACTCCGCCCAATAtTACTTAGACAGTTTAGATCGAATCGGAGCTGCAGATTACCAGCCCACAGAGCAGGACATTCTGCGAACTCGAGTGAAGACCACCGGGATTGTAGAAACCCACTTCACCTTCAAGAACCTGCATTTCAGGCTGTTTGATGTGGGAGGTCAGAGGTCGGAGAGGAAGAAATGGATCCACTGCTTTGAGGACGTGACCGCCATTATCTTCTGTGTGGCTCTGAGTGGATACGACCAGGTGCTCCATGAAGACGAGACCACGAACCGCATGCACGAGTCCATGAAGCTTTTTGACAGCATCTGCAACAACAAATGGTTTACAAACACCTCCATCATTCTCTTTCTCAACAAGAAGGATATATTCGGGGACAAAATTAGGAAATCTCCCTTAAGTATCTGCTTTCCGGAATACACAGGTTCGAACACGTTCGAGGAAGCGGTGAATTACATTCAGTCCCAATACGAGAGCAAGAACAAGTCAGTGGAAAAGGAGATCTACTCGCACATCACCTGCGCTACAGACAcagacaacattcagtttgtttttGACGCCGTCACTGACGTCATCATAGCCAACAACCTGCGCTTCTGTGGCCTCTACTGAGTCTACGCACTG

Function

symbol description
gnao1a Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and dopamine receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Is expressed in gill; nervous system; neural rod; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Orthologous to human GNAO1 (G protein subunit alpha o1).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway biological_process
GO:0007212 dopamine receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005834 heterotrimeric G-protein complex cellular_component
GO:0051430 corticotropin-releasing hormone receptor 1 binding molecular_function
GO:0003924 GTPase activity molecular_function
GO:0031821 G protein-coupled serotonin receptor binding molecular_function
GO:0005525 GTP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0019001 guanyl nucleotide binding molecular_function
GO:0031852 mu-type opioid receptor binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0031683 G-protein beta/gamma-subunit complex binding molecular_function
GO:0001664 G protein-coupled receptor binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1757 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and dopamine receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Is expressed in gill; nervous system; neural rod; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Orthologous to human GNAO1 (G protein subunit alpha o1).

Ensembl:

ensembl_id ENSDARG00000016676

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025538 False 2401 mRNA 0.46 8 22793465 22975655
TCONS_00025539 True 1089 mRNA 0.50 8 22793743 22960531

Neighbor

gene id symbol gene type direction distance location
XLOC_012800 bcar1 coding upstream 105392 22504200 ~ 22688073 (+)
XLOC_012799 cfdp1 coding upstream 306698 22416051 ~ 22486767 (+)
XLOC_012798 carmil2 coding upstream 397094 22302635 ~ 22396371 (+)
XLOC_012797 ctcf coding upstream 498401 22285992 ~ 22295064 (+)
XLOC_012796 ripor1 coding upstream 510067 22138924 ~ 22283398 (+)
XLOC_012802 cbfb coding downstream 18458 22994113 ~ 23072665 (+)
XLOC_012803 mef2aa coding downstream 211764 23187419 ~ 23356077 (+)
XLOC_012804 mctp2a coding downstream 398028 23373683 ~ 23456101 (+)
XLOC_012805 NA coding downstream 483274 23458929 ~ 23463541 (+)
XLOC_012806 AL805905.1 coding downstream 496491 23472146 ~ 23472260 (+)
XLOC_012793 NA non-coding upstream 693237 22099619 ~ 22100228 (+)
XLOC_012792 CT573204.1 non-coding upstream 711712 22078144 ~ 22081753 (+)
XLOC_012790 NA non-coding upstream 1320101 21469636 ~ 21473364 (+)
XLOC_012787 BX571884.1 non-coding upstream 1601681 21191665 ~ 21191784 (+)
XLOC_012786 NA non-coding upstream 1623717 21163424 ~ 21169748 (+)
XLOC_012807 NA non-coding downstream 835729 23811384 ~ 23828058 (+)
XLOC_012808 NA non-coding downstream 900785 23876440 ~ 23889042 (+)
XLOC_012809 CR847971.1 non-coding downstream 1501871 24477526 ~ 24483285 (+)

Expression


Co-expression Network