XLOC_001399 (dok7)


Basic Information

Item Value
gene id XLOC_001399
gene name dok7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 41142881 ~ 41192206 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00002300
TGCATGTGTGAGTATTGTGGGGGAGAGAGAGTTTGCGTGTGTGTTACAGCAGAGCAGACAGTGAATTCTGGAGGTTATTTTGAAAGTGAccccctcactcactcactgccgCGGACCGCACACAGCTGTCGGGAAACATGACACAAGATGACGGATACGGTTGTCGTAGAGGGACAAGTCAAACTCCGAGAAGGCAAAAAGTGGAAAAACAGATGGGTGATTCTTCGGAAACCTTCGCCGGTAGCAGACTGCCTGTCCTTGCTGGTGTATAAGGAGCGGGGAGAGAAAAGCAAAGGACAGCGAGAGAGGAATCAGGCCACACTGAGGGATATCTGTGGACTGGAGGCTCTTCAGGGCTTTGATGGAGTAAATTATGCTCTCAGTCTGCTCTGCCTGAGCCAGTCTGTCATGCTGGGTTTCGACAACAGAGTGTCTCTTCTGGCCTGGGATGCTCGGATCCGCTACAGCCTTGGAGAGGTTCACAGGTTCAACGTCAACATCCAGCCTGGCACCAAACTAGAAAGTGGCCCGGCCTCTTTGCATTTGTGCAACAACCTGCTTGTCGTTGCCAGAGACCTCCCTCCAACCGTCATCGGCCAATGGAAGCTGTCGGATCTAAGACGTTACGGTGCCTTTCCTAATGGATTTGTCTTTGAGGGCGGGACAAGATGCGGCTACTGGGCCGGGGTTTTCTTTCTTGCGTGTGCAGATGGAGAACAGATCAGTTTTTTGGTGGATTGCATCGTTCGTGGCATTTCGCCAAGCAGAGGGCCGTTTGGACTGCGGCCAGTCCTGCCAGACCCCAATGCTAACCCGTCGTCTATAGAAGACCGGATTAGCCAGGAGGCTAGTGAGCTGGAGAAAAGACTCAGCATGCTGTCCATTTGTAGTCACCACAGCAGTGCAGCCTCCACCTTCAGTTATGGCGCCTCTTTGGCAGGAGATGATCGAAGTATCTCCAGCTCGTCCTCTGAGGCCAGCCATTCTGATAACAGCTTGGGCAGCCGCCTGGCGATCTGGCCGGAGCCAGTCAGACACCCCACCCCTGTCGAACCACCACcgccaccaccatcatcatcatcatcatctcattTATTGGTTACAGGATGTAAAAGCACAGCCTGTTCAGTCAGTACGTCCAGTGACGAGCGCATATATGGAGTTATGATGGGTGGACTTCGCCCCCCGTCCAAACCCCCTCACCCTAGGGGCCTTCAGGAGGCGGGACGGCAGAGCTCCACAGACAGCGGCATCGCCACCGGAAGCCACTCCTCATATTCGGGAAGCTTCTCCTCTTACACTGGGAGCATGGATATTGGCCATGGAGAGACTGACGAGTTTGGATCCTTAATAAGCCTTCCTCAAAACCCCAATTCAGTCTCTATTATAAACACTCCAGTAAGGACAGTTCCCCAGATTCCTGAGGACAACCCATGTGTGTGTTCTCTCCGAGAGGCTGATCAAACACAGGCCAACGTATACACAAGTTCACCTCTGCAGCATTACGATGTCCCTCGCAGGTTCCTACAACACAATCAGGAGCAGTGTTCCACTGGTGTGGTTCAGGACAGAGGGTCTGAATGTGGAGCGGAGAGTGTCCCTGCTGACAACGTCATAAGACAGACTGTCCTGAGGAGATTGAACTCTTGTGGAGTAGACGCAGTGCCACCTGAAGGTCCCACCACAACACGCTTACAACCCATCATCTGTCCTGACTGTGGCGGACGAAAGGTGGAAGAGAAAAGCCGTTCTGAGCAGCAGAAGACTGATGCAGATCCAAAAGGCAATTATGAACAGATGGCATTGATGAGTGATTTGTCCAGGTGGACACAGTTCAGAGCCGGAGAGTATGGTAATTCACATGCCCTCATTTCATATATCTCTCCATCGGATCATAGCATTTCGTTACTATCTGTGTATGAATCTGGTTTCTGCTGTGGTCTTACAGGAGAGGCCGGACTGACAGTCACTGACAGAGCTCAAGGTGATTCTGTAAATTATGTTAACATCCCCATCAGTCCTACATCTAAACGACAGCTGCACTATATGGAGCTGGATCTGCAGGACCGTCCTGAATCAAGCCACACTATCAGAGCGGCTGGCTCCAGCACTAAATATGCCCACATTGACATCACTGCGACAGAGACGGCACAGAGGGTTGGTGCCCAGCATGCACAGGGCAGAGAGGATAGACTGCTGGAACTAGAGCACAAGAGGAGAGGAacactcacataaacacacaaagtattttaatatgaTGAGGATTTTTCTCTCCATTCAAGCCcagaaatatttgtattttttactgtAGAGATTTAAGGGGGGAGATGATTCTTTTAATTTCTtcttttgacatttggattttaataataaataaactttaaaaagatAAAAGCATAGATCTAGTATAGAATATTTAACCTGCAGCCATGTACCTGGAAATGTGGCAccacttttcatttttttacatttaaaaatattcttgatgtcttttttttaaattctgtcaaAATTGTTTgcagattaaatttttttctctCAAACTTCCATGAAACACATCATCagcttttaaacacattttcaaaccCTGATCTacagaaaacagttattttataagaAATTCATTCTTCAGGcattttttcttaaatgtttttactCATTGTGATGCTAAAATATGTAAGTTAAATGCAAAATATAATCGCTTTTATAAGTGATCTCTTTATggttcactatatatatatatatatatatatttatcagtgGTTCTAAATATTATTTACCTTATAAAGTAATCATCCTACACAACCAAAATGGAAAGTGAAATGCAGCCTTCCaaaaataagatgtttttatttatttatataaaattaatcaaTTTGCAGATGTGACTGacagtgtaatgtaatgtaatgtgtatttatatagcacattcatCGTGTATCATCCAC
>TCONS_00002301
ATGACGGATACGGTTGTCGTAGAGGGACAAGTCAAACTCCGAGAAGGCAAAAAGTGGAAAAACAGATGGGTGATTCTTCGGAAACCTTCGCCGGTAGCAGACTGCCTGTCCTTGCTGGTGTATAAGGAGCGGGGAGAGAAAAGCAAAGGACAGCGAGAGAGGAATCAGGCCACACTGAGGGATATCTGTGGACTGGAGGCTCTTCAGGGCTTTGATGGAGTAAATTATGCTCTCAGTCTGCTCTGCCTGAGCCAGTCTGTCATGCTGGGTTTCGACAACAGAGTGTCTCTTCTGGCCTGGGATGCTCGGATCCGCTACAGCCTTGGAGAGGTTCACAGGTTCAACGTCAACATCCAGCCTGGCACCAAACTAGAAAGTGGCCCGGCCTCTTTGCATTTGTGCAACAACCTGCTTGTCGTTGCCAGAGACCTCCCTCCAACCGTCATCGGCCAATGGAAGCTGTCGGATCTAAGACGTTACGGTGCCTTTCCTAATGGATTTGTCTTTGAGGGCGGGACAAGATGCGGCTACTGGGCCGGGGTTTTCTTTCTTGCGTGTGCAGATGGAGAACAGATCAGTTTTTTGGTGGATTGCATCGTTCGTGGCATTTCGCCAAGCAGAGGGCCGTTTGGACTGCGGCCAGTCCTGCCAGACCCCAATGCTAACCCGTCGTCTATAGAAGACCGGATTAGCCAGGAGGCTAGTGAGCTGGAGAAAAGACTCAGCATGCTGTCCATTTCCTCCACCTTCAGTTATGGCGCCTCTTTGGCAGGAGATGATCGAAGTATCTCCAGCTCGTCCTCTGAGGCCAGCCATTCTGATAACAGCTTGGGCAGCCGCCTGGCGATCTGGCCGGAGCCAGTCAGACACCCCACCCCTGTCGAACCACCACcCACAGCCTGTTCAGTCAGTACGTCCAGTGACGAGCGCATATATGGAGTTATGATGGGTGGACTTCGCCCCCCGTCCAAACCCCCTCACCCTAGGGGCCTTCAGGAGGCGGGACGGCAGAGCTCCACAGACAGCGGCATCGCCACCGGAAGCCACTCCTCATATTCGGGAAGCTTCTCCTCTTACACTGGGAGCATGGATATTGGCCATGGAGAGACTGACGAGTTTGGATCCTTAATAAGCCTTCCTCAAAACCCCAATTCAGTCTCTATTATAAACACTCCAGTAAGGACACATTACGATGTCCCTCGCAGGTTCCTACAACACAATCAGGAGCAGTGTTCCACTGGTGTGGTTCAGGACAGAGGGTCTGAATGTGGAGCGGAGAGTGTCCCTGCTGACAACGTCATAAGACAGACTGTCCTGAGGAGATTGAACTCTTGTGGAGTAGACGCAGTGCCACCTGAAGGTCCCACCACAACACGCTTACAACCCATCATCTGTCCTGACTGTGGCGGACGAAAGGTCATTTCAAAATTGTTTTTATGTTGA

Function

symbol description
dok7 Enables protein kinase binding activity. Involved in positive regulation of protein tyrosine kinase activity. Located in mitochondrion and nucleoplasm. Implicated in congenital myasthenic syndrome 10 and fetal akinesia deformation sequence syndrome 3.

GO:

id name namespace
GO:0048741 skeletal muscle fiber development biological_process
GO:0007528 neuromuscular junction development biological_process
GO:0007416 synapse assembly biological_process
GO:0061098 positive regulation of protein tyrosine kinase activity biological_process
GO:0001966 thigmotaxis biological_process
GO:0019901 protein kinase binding molecular_function

KEGG:

id description
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-090312-103 Predicted to enable protein kinase binding activity. Acts upstream of or within skeletal muscle fiber development; synapse organization; and thigmotaxis. Is expressed in post-vent region and tail bud. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10 and fetal akinesia deformation sequence syndrome 3. Orthologous to human DOK7 (docking protein 7).

Ensembl:

ensembl_id ENSDARG00000060236

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00002300 False 2948 mRNA 0.46 10 41142881 41192206
TCONS_00002301 True 1443 mRNA 0.53 9 41155671 41192059

Neighbor

gene id symbol gene type direction distance location
XLOC_001398 adra2c coding downstream 148622 40992682 ~ 40994259 (-)
XLOC_001397 hmx1 coding downstream 228129 40912613 ~ 40914752 (-)
XLOC_001396 hmx4 coding downstream 231549 40909750 ~ 40911332 (-)
XLOC_001395 zgc:153642 coding downstream 407500 40733921 ~ 40735381 (-)
XLOC_001394 NA coding downstream 478176 40648878 ~ 40664705 (-)
XLOC_001400 rgs12b coding upstream 9380 41201586 ~ 41287914 (-)
XLOC_001401 htt coding upstream 101758 41293964 ~ 41374117 (-)
XLOC_001402 CR974461.2 coding upstream 119571 41311777 ~ 41311892 (-)
XLOC_001403 NA coding upstream 299095 41491301 ~ 41493481 (-)
XLOC_001404 NA coding upstream 340458 41532664 ~ 41533488 (-)
XLOC_001393 NA non-coding downstream 494736 40647644 ~ 40648145 (-)
XLOC_001390 NA non-coding downstream 804479 40333894 ~ 40338402 (-)
XLOC_001389 NA non-coding downstream 834256 40268545 ~ 40308625 (-)
XLOC_001385 NA non-coding downstream 986016 40156021 ~ 40156865 (-)
XLOC_001405 NA non-coding upstream 395949 41588155 ~ 41591134 (-)
XLOC_001406 NA non-coding upstream 407012 41599218 ~ 41608702 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000049_07448242_07471903 DOK7 coding CI01000049 null 7448047 ~ 7471903 (-)