XLOC_017204 (itpa)


Basic Information

Item Value
gene id XLOC_017204
gene name itpa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 14941264 ~ 14949443 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034267
ACTGAAGCATGGCAGTACCGACCGGTAGAGCGTTGGTTTTCGTTACCGGGAACGCGAAAAAGTTGGAAGAGGTAGTTCAAATCCTTGGTGACAAATTTCCCTACAAACTGATTTCTAAAAAGATTGACTTGCCTGAATATCAAGGTGAACCAGATGACATTTCCATACAGAAGTGTAAAGAAGCAGCAAGGCAGGTTGATGGGCCAGTGCTGGTAGAGGACACCTGTCTGTGCTTCAGAGCTTTAGAAGGACTGCCAGGACCTTACATAAAATGGTTCTTGGATAAACTGAAGCCTGAAGGATTGTACAAAATGCTGGCGGGTTTTGAAGATAAATCAGCCTGGGCTCTGTGTACGTTTGCTTTCTGTGCTGGAAAAGAGGAGCCAGTTCAGCTGTTCAGAGGAATAACTGAGGGTCATATTGTTGAGCCCAGGGGTCCAAGAGATTTTGGGTGGGACCCCTGTTTCCAGCCTGAGGGCTATGACAAAACTTATGCTGAGCTTCCTAAAGAAGTGAAGAACAGTATTTCTCATCGGTACCGCGCACTGGCAGCTCTGTCTGAACACTTCTGTCAGGATAACGGCGCACCAGAGACCAAGCGCTCAAAACACCAGGACTAAGGACGCATCTATCTGTTTCCAAACCGAATCAGCCTGTCAGAGTGCAGTTTGCCTCATCAGTCCAGTGATTGCATGGATGTGCTGTTCAGAAGCGGTTAAAgtaacttttaaataaatgttttgtttataaaa

Function

symbol description
itpa Predicted to enable nucleoside-triphosphate diphosphatase activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to act upstream of or within nucleotide metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); developmental and epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase).

GO:

id name namespace
GO:0009117 nucleotide metabolic process biological_process
GO:0009143 nucleoside triphosphate catabolic process biological_process
GO:0009204 deoxyribonucleoside triphosphate catabolic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0035529 NADH pyrophosphatase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004551 nucleotide diphosphatase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0047429 nucleoside-triphosphate diphosphatase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0036218 dTTP diphosphatase activity molecular_function

KEGG:

id description
ko00230 Purine metabolism
ko00983 Drug metabolism - other enzymes

ZFIN:

id description
ZDB-GENE-070705-218 Predicted to enable nucleoside-triphosphate diphosphatase activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to act upstream of or within nucleotide metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); developmental and epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase).

Ensembl:

ensembl_id ENSDARG00000057529

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034267 True 752 mRNA 0.46 8 14941264 14949443

Neighbor

gene id symbol gene type direction distance location
XLOC_017203 mir214a coding upstream 63526 14877639 ~ 14877738 (+)
XLOC_017202 mir199-3a coding upstream 65718 14875460 ~ 14875546 (+)
XLOC_017201 pigc coding upstream 125772 14810886 ~ 14815492 (+)
XLOC_017200 tmed5 coding upstream 134593 14789148 ~ 14806671 (+)
XLOC_017199 BX901920.1 coding upstream 279832 14657141 ~ 14661432 (+)
XLOC_017205 vamp4 coding downstream 18588 14968031 ~ 15006337 (+)
XLOC_017206 FP074855.1 coding downstream 49513 14998956 ~ 14999072 (+)
XLOC_017207 myoc coding downstream 66114 15015557 ~ 15021628 (+)
XLOC_017208 NA coding downstream 106553 15055996 ~ 15058705 (+)
XLOC_017209 NA coding downstream 162293 15111736 ~ 15114901 (+)
XLOC_017198 NA non-coding upstream 317346 14487757 ~ 14623918 (+)
XLOC_017196 NA non-coding upstream 793780 14144076 ~ 14147484 (+)
XLOC_017211 NA non-coding downstream 335821 15285264 ~ 15286146 (+)
XLOC_017212 NA non-coding downstream 579528 15528971 ~ 15529445 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000051_03107566_03109607 ITPA coding CI01000051 null 3107566 ~ 3109730 (+)