XLOC_017359 (chga)


Basic Information

Item Value
gene id XLOC_017359
gene name chga
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 27020201 ~ 27045991 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034535
CGCTGCGGTAGCGAGTAGTGGCACTGAGGCATTGTGATCTGAGGAACCGACGAAACAAACACGAGCAGCGCCTAATGCGCAATAATGCATCCCTAAATCAGCCAGTGACTTCATTTATTGTGAGGACAGGGAAATACTGACGTTCATTCGCTTTCGCTCGCCCCTTTTCAGCAGAACAGATGCCTGCACTTCGCATCACGAGAATGATCGCGCGAGGATGCGTTGCTCTCCTGCTCCTGGTGAATGTTGTCATCTCCGTGCCAGTTTCTCCAGGTCACATGGAAGAGAAGGATGTGAAGGTGATGAAGTGTATTGTGGAAGTGATTGCAGATGCTCTGTCCAAGCCTCATCCCATCCCAGTGTCCCAGGACTGCCTTGAAACGCTCAGCACTGATGACAGGCTCGTGAGTATCCTGCGCCACAGAAACTTTCTCCGAGAGTTGCAAGACATCGCAGCTGAAGGAGCCAGCGAGAGAGCGCTGAAACTCCCAGGAGATGCGCCTGATCATGTGACCAGCCTCCCTAAAGACTTGAAGAAAACTGCAGAAGGGCCAACAGCCACAGATGATGTTGAAGTGAATCCCGATGTGAAACAATCCATCATGGAGGACAATCAGGAGCACAAAGGAGACGAAACTGAGAAAACGCATTCAAAAGAAGAACCAGAAGAAGACGAGGAGGAGAAGAAAAGAGAGGTTGGAGTGAAGCGCTGGAGCCGTGTGAGTAAAGTGTCCCACAAGAGAGTGGAGATGAGCCCAAAAGTAGATGAACGCTGGGAGTCCAAGCACTCCAAGGAGAGAGAGGACCCAGAGGGGGATCTGTGGAGGAGCCCAGAGGAGCAGGAGCTGCAGCTGATGGCCCAAACCCAAACGCAGGACAAACGTGAAGAAGAGGGCAGCGGCAGCAGGAAGACTGGG
>TCONS_00034536
CGCTGCGGTAGCGAGTAGTGGCACTGAGGCATTGTGATCTGAGGAACCGACGAAACAAACACGAGCAGCGCCTAATGCGCAATAATGCATCCCTAAATCAGCCAGTGACTTCATTTATTGTGAGGACAGGGAAATACTGACGTTCATTCGCTTTCGCTCGCCCCTTTTCAGCAGAACAGATGCCTGCACTTCGCATCACGAGAATGATCGCGCGAGGATGCGTTGCTCTCCTGCTCCTGGTGAATGTTGTCATCTCCGTGCCAGTTTCTCCAGGTCACATGGAAGAGAAGGATGTGAAGGTGATGAAGTGTATTGTGGAAGTGATTGCAGATGCTCTGTCCAAGCCTCATCCCATCCCAGTGTCCCAGGACTGCCTTGAAACGCTCAGCACTGATGACAGGCTCGTGAGTATCCTGCGCCACAGAAACTTTCTCCGAGAGTTGCAAGACATCGCAGCTGAAGGAGCCAGCGAGAGAGCGCTGAAACTCCCAGGAGATGCGCCTGATCATGTGACCAGCCTCCCTAAAGACTTGAAGAAAACTGCAGACGATCAGTCAATGCTGGTTGCCATGGAGAAACCAGAAAAAGAAACAGAGAAGCGAGGAGCAGGAGAGGAGAGCGAGGAGACAGAGCAGCAGTCTCAGAAACAAAACCAGATTATTACTGAGGAAGACCACAGTAAggaacaagaagaagaagaagaaaagaatcaCATCTCTAACTCCTTAAATCCAGAGCCGAAGACAGACTCACAGGAGGAGACAACGATAAGAGATGAGGAGAGGAAACACTCCAGCTCAGAAAATGAGGAAAACGATCCGGCTCATAAAGAGGAAGGGCCAACAGCCACAGATGATGTTGAAGTGAATCCCGATGTGAAACAATCCATCATGGAGGACAATCAGGAGCACAAAGGAGACGAAACTGAGAAAACGCATTCAAAAGAAGAACCAGAAGAAGACGAGGAGGAGAAGAAAAGAGAGGTTGGAGTGAAGCGCTGGAGCCGTGTGAGTAAAGTGTCCCACAAGAGAGTGGAGATGAGCCCAAAAGTAGATGAACGCTGGGAGTCCAAGCACTCCAAGGAGAGAGAGGACCCAGAGGGGGATCTGTGGAGGAGCCCAGAGGAGCAGGAGCTGCAGCTGATGGCCCAAACCCAAACGCAGGACAAACGTGAAGAAGAGGGCAGCGGCAGCAGGAAGACTGGGGATGCTGAGATCGAGAGTCTGGCTGCCATTGAGTCTGAATTAGAGAGCGTGGCTCAGAAGCTCCATGATCTGAGACGAGGCTGATCGGCTCCAGCTCTCCTTCTCTTTCACGTCTGCCCTTCATCTCTCCTTCAGTAGAAAGGCATGTAAACTGGAGATGAGGCTCAGTTCACAGCAGCGCAAGCTCTTATCTCAGTGCTCCTTCCCTACACGTGTAACATCAACCCTCGAAGCCAAAACATTTATATCCCTTCTCTTTCCCTGCGCTCCGCTTTGCTTTATCGTGCTTGCTTCCTGAAGAAATTTGGGCATTGAGTACATACTGTCTCAAATATTTGCTAAAAACTAGCTGGAATTATCACGCTAgattgacattttaaatatactCAAGAGTACACATCTGAAAGATTGTACCTGATAATATGGAGTCTTATGATCTATAtgcaataataatgtttttattaaatatggtGACGACTGTGTTTAAATGGTTTTTGGGTTTccagaaaacaaataaagaagTGTTTCAAAGTGA

Function

symbol description
chga Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation; defense response to bacterium; and negative regulation of secretion by cell. Predicted to be located in extracellular region. Predicted to be active in chromaffin granule and extracellular space. Is expressed in nervous system; otic vesicle; trigeminal placode; and trunk neural crest. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypertension; and prostate cancer. Orthologous to human CHGA (chromogranin A).

GO:

id name namespace
GO:0042742 defense response to bacterium biological_process
GO:0046888 negative regulation of hormone secretion biological_process
GO:0046676 negative regulation of insulin secretion biological_process
GO:0086030 adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation biological_process
GO:0033604 negative regulation of catecholamine secretion biological_process
GO:0030141 secretory granule cellular_component
GO:0005615 extracellular space cellular_component
GO:0042583 chromaffin granule cellular_component

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-041010-161 Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation; defense response to bacterium; and negative regulation of secretion by cell. Predicted to be located in extracellular region. Predicted to be active in chromaffin granule and extracellular space. Is expressed in nervous system; otic vesicle; trigeminal placode; and trunk neural crest. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypertension; and prostate cancer. Orthologous to human CHGA (chromogranin A).

Ensembl:

ensembl_id ENSDARG00000008829

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034535 False 917 mRNA 0.52 6 27020201 27039634
TCONS_00034536 True 1740 mRNA 0.48 8 27020201 27045991

Neighbor

gene id symbol gene type direction distance location
XLOC_017358 si:dkey-177p2.18 coding upstream 7242 27003558 ~ 27012959 (+)
XLOC_017357 sel1l coding upstream 16903 26987416 ~ 27003298 (+)
XLOC_017356 ahsa1a coding upstream 45953 26966725 ~ 26974248 (+)
XLOC_017355 si:dkey-177p2.6 coding upstream 57360 26947800 ~ 26962841 (+)
XLOC_017354 cdca4 coding upstream 73953 26939742 ~ 26946248 (+)
XLOC_017360 tmem251 coding downstream 41548 27087539 ~ 27090853 (+)
XLOC_017361 ubr7 coding downstream 47051 27093042 ~ 27107709 (+)
XLOC_017362 NA coding downstream 62715 27108706 ~ 27113992 (+)
XLOC_017363 NA coding downstream 148861 27194852 ~ 27198481 (+)
XLOC_017364 si:dkey-85n7.6 coding downstream 194397 27240388 ~ 27283820 (+)
XLOC_017351 BX248515.1 non-coding upstream 117933 26899745 ~ 26902268 (+)
XLOC_017348 NA non-coding upstream 314172 26704384 ~ 26706029 (+)
XLOC_017344 BX537272.1 non-coding upstream 425322 26594764 ~ 26594879 (+)
XLOC_017340 NA non-coding upstream 660767 26095530 ~ 26359434 (+)
XLOC_017339 AL954831.1 non-coding upstream 954257 26059710 ~ 26065944 (+)
XLOC_017365 NA non-coding downstream 251153 27297144 ~ 27372450 (+)
XLOC_017366 BX255913.3 non-coding downstream 292015 27338006 ~ 27338121 (+)
XLOC_017368 dre-mir-203b non-coding downstream 359887 27405878 ~ 27405962 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G465562 NA misc CI01000325 null 5520774 ~ 5530557 (-)