XLOC_017436 (sec63)


Basic Information

Item Value
gene id XLOC_017436
gene name sec63
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 32501748 ~ 32521973 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034659
CTGGCTTCCCTCGCCGCATATGTGAGTAGTTCTACAGTGGAGTGACTGATAGGGCGGCAAGGCGGCAGAAAAGATCAGGGTTTATTGCCGCTTCGAAATGGCCGGACAGCAGTTTCAGTACGACGACAGTGGCAACACTTTTTTCTATTTCCTCACGTCCTTTGTGGGACTCATAGTCATCCCAGCAACCTATTACATCTGGCCTCGGGATCAGAATGCGGAGCAATTGCGATTGAAGAGTTTACGGAGAGTTCATGGAAGATGTCTGTGGTATCGCCTTCGGCTTATGAAATCACAGCAGAGCATTGTTCCAACACTTAAAAAAGCAGCCCTGTTGTTTGGGTGGGCAGTATTTCTTCTCCTGGCATATAAAGTGTCTAAATTAGATAGAGAGTACCAGGAATATAACCCTTATGAAGTCCTCAACTTGGAAGCAGGGGCATCTGTTGCTGAGATAAAGAAGCAGTACAGGGTGCTGTCTTTAAAACATCACCCTGATAAAGGCGGAGATGAGGCTACCTTCATGAAGCTTGCTAAAGCTTACTCAGCTTTGACTAATGAGGAATCGCGGAAAAATTGGGAGATGTACGGCAACCCTGATGGCCCAAGAGTGACGAGTTTTGGAATCGCTCTTCCTGCATGGATTGTTGATCAGAAAAATTCCATGCTGGTGCTGCTGGTCTATGGGTTGGCATTTATGGTCATACTTCCTGTGGTAGTGGGTACGTGGTGGTACCGTTCCATACGCTACAGTGGTGATCAGATCCTGATCAACACAACACAGCTTTTCATGCACTTTATGTACAAAACGCCTACAATGAACATGAAACGATTGGTAATGGTGTTGACGGCTGCATTTGAGTTTGATCCTCGTAGTAACAAAGAGGCCATCATAAGGCCGACAGACAACATTGAAGTTCCTCAGTTGATTCGGGAGCTGGGAAATATTAACGTTAAGAAGAAGGAACCTCCGTTCTGCTATCCTTATAGCCTGAAGGCTCGAGTCTTATTACTTGCACAACTTGCCAGGATGGATGTTTCTGAGAACATAGAGGAGGATCAAAGGTTTGTGGTGAAGAAGTGCCCTGCCCTGTTACAGGAAATGATCAATGTTGGCTGTCAGCTCACCATGATGGCAACTAGTAGAGGAGGCCTTCGGGCTCCCAGGCTCACATCCATAGAAAACTGCATGAAGCTTTCTCAAATGGTGGTTCAAGGTCTGCAGGAGGCCAAATCTCCTCTGCTGCAGCTGCCCCATTTCGAAGAGGAGCACCTCCGATACTGTATCTCTAAGAAGTACAAGGTGCGGACGTTGCAGGATCTGGTCAGCCTGAAAGACTCTGACAGGAGGAACATGCTAAGATTTCTGGGGGAGGAGAAGTATGATGAGGTCATTGGAGTCCTCGGCAGCTTCCCTTATATCAACATGGAAACCAAACTTCAAGTGCTGGATGATGAAGATAGCAATAACATCACTGCAGGATCCATTGTCACAGTCACGGTCATCTTGACAAGGAAGAGAATGTCTGAGATGTTTGAGAAGGAGGAGAACGCACCGCTGCCTGCAGAAGAAGTGAACACAGAGGAGCAAGGTgatgccaaaaataaaacaaaggttTGGCAAAATAAGAATAAAGGAGCTAAAAAAGCTGCCAAGTCCAAAAAGAAGAAACTGACTAAGAAGAAACCAGTCACTCAACAGCAAGCGAAGGGAGACAAGGCCAAACAAGCCAATGGCAACGTGGCTGGAAATGAAGTTGTGTcaaaagaagaagaggaagatcTGTCTGACAAAGGCAGCGAATCAGACGAAGCAGAGGGAAATAAGGACTCACCCAGTGAAAGAGATGATGAGAGCGACAAGCAGAGCGACACTGAAGGGGATGAGATCGCCAGAGATGACGaggagGAATGGGAGGCTCTACAGCAAAGCATTCAGCGGCGTGAACGAGCACTGTTGGAGACCAAGTCTAAGGTCACTCATCCAGTCTACAGTCTGTTCTTCCCTGAGGAGAAGCAGGAGTGGTGGTGGCTCTACATCGCAGACCGGAAGGAACAGACACTGGTGTCCATGCCCAACCACGTGTGCACACTCAAAGACACAGAGGAGGTTGAACTGAAATTCCCTGCTCCATCCAAAACTGGAAACTATCAATATTCAGTGATTCTCAGATCAGATTCGTTCATGGGACTAGATCAGATCAAGCCACTTAAGCTGGAGGTTCATGAGGCGAAGGCCATGATGGATAACCACCCGCAGTGGGACATCCCAGAaactgaggaagaggaggatgacCAGGAGGACAGTGACGGCATTGAGGAGTCTGAGGAAGACGAAGAAGACAACGACTAAAATCATTTCATGCAAACTTGAGCACAGCTCATACACCCATGTgcccgctcacacacacacacacacacctacacacacagcCCCGGACTTCTGGGCCACCATACACACCAGAAGCAAACAGGAGACAAGGACGTTGACGCCCCATGATCCTGTTTAAAACACTCATGAATCACATTTATTTCGCCAGTCAAACACTCGGTTCTCTTTCCCTGCGTTCATCCAGTCGTTATCAGTGGGCTTTCACCATGGTTATCTGTGGGTTCCAGCTGTGTTTCAGATTCCTCTCCACTTGACGAAAAAGATGCATCGGAATAAATAAAACCAGATTTCCgctttaaaaagagaaaaaaaaaatcccacaccTCACGACTCATTTTCAATCTCACTGTTTATGCTTCAAGGGTTTTCTACCTTCTCATTTTGTAGTTTTCTGTAGTTTGTTAGATATCAGATTTACCAGGTGTCTCCACTTTTATGAGGCTGTGTGAATCCTGTTCTCTGGAGTGAACCACAGAGACGTGGTATGTGTGTTCTGAGCTTTGGCAGGAACCATAGGATGGAGTGACCATGACCTCGGTTGGTTATGAAGTGTGGAAGTTTAATGCATTTATGAATCTCACAGTTCTTCTTCCAGCTTTGTCATATTTTCTCAGCTTCATAGAAAATGACTGCAGTCATTCCTACAGATTTAACTCACAATTAAAACTGCTGTCCTGCTGTTCCACAAATAAGAATTTTTTGGCACTATGTAAAAACATGActcaaattttagtttttttaatacgTTTTTTTTCAGGTTTGAAAATAGACAACTGCAGTTGTTACAGAGACCATATTTTCAGTACGAACGTACACAAGTACAGTTGCATCAAAATCAGAAACATCCAAAAAGAAATTGGATCTTTTTGCCTCGTCTcagaattgtattattttttttctttaatttagatGATATCATCTTACATTCCACTCTCATCAAATAGAAACGCCTTATTCACTGTATAGAGTTTTCAGTAAatgcaaatggtttgtaaatgaaACCATCAATACGAGTGTTGGGAATGTTTATTTCTGCAAGTTTTTCgagttttgtttttaagtgtggATGGCAATAGGGCTCAAGATTaagggcgttttttttttttttagatataattACTTTCGtccaatttaaatgttattttgcaCCAGTGGAAGGTCTGACAGTGTATTGGAAGTGCTGGTTTAGTGGTTGTGAAAATATTATTCCGGTCTGTTCATTTGTAAATTGGTTGAGGAGAGATTAAGCTGACAGAAATTATTTGAAATGCATATAAAACATAATCTCTCCATATAAtgttaattttttctttcttttctttttaaatcttgAGTTTATGAATGAAATTGGATTTtgtatttttccctaatttgttACAATTTTAAAACTGCAGACACCAGTAGAAAATCCaattttatttgacttatttccACACATTAGCATAAGCAATTCAATTACTGATGGAGGGAAAGTGTCATATTTTGGCTGCATGTCAACTCACGTTCACAAAGTTTTATAAAATGATGATGGTTTTacagataaataaacattttagtgTTATAGctccaaaaaaagaaagaaggaaaaaaagattGTAGCCTCAGAAACTAATGCTGAGTTCTGATGTGCACAGATGATGACAAATTGtctccacatacacacacagagaaactCACCGGCCAGAAAAAAAAGGGGTTGAATTGCCTAGTAAACAGTATCTGCCACTTTTGTTTACAAGAAAAACTGTCATTGtaaatggaaaatatatattatttgtatttaaataatttcaaataaaataactttttaaatga
>TCONS_00034660
GCATATGTGAGTAGTTCTACAGTGGAGTGACTGATAGGGCGGCAAGGCGGCAGAAAAGATCAGGGTTTATTGCCGCTTCGAAATGGCCGGACAGCAGTTTCAGTACGACGACAGTGGCAACACTTTTTTCTATTTCCTCACGTCCTTTGTGGGACTCATAGTCATCCCAGCAACCTATTACATCTGGCCTCGGGATCAGAATGCGGAGCAATTGCGATTGAAGAGTTTACGGAGAGTTCATGGAAGATGTCTGTGGTATCGCCTTCGGCTTATGAAATCACAGCAGAGCATTGTTCCAACACTTAAGTAAGTGATTATGTTTGTCTGTAATTAGTTGAAAGAATTTCAGGTCAATTAATCCTATTTAACTCATTGCGTGTAGTTGTATGATGCACTTGTGCCATTCTTTTTGGTGTTATTTGTAACTTTTAGTTTTCTTGAAATAGCTTGCAATGTGAGATCTTAATATCTGTTCAAATAAATTGGATTAAACCAGAGATTATTTGAAGGTACTTGATGGATAACAAAAAATGAACCTACTCCCGTCATGGTCTGGCTGTAAAGTTCTTTTATTGTCACGTCAGAAGGAGTGTATAGTTCC
>TCONS_00034661
AGTCTGACAGCGAGAGCTTCCTCTCTGTGAGGAGCAGGAGAATGAACGGATGTAAACACAGGGGTCATAAATCAGCCCAGATCGCCCAATTACTCAAGTCTATTATATTTTGCTGAGCTGTGGAAAGCAACCAGTGACTATATAACTTCCTGTTTTCCTCAGGTTGAACTGAAATTCCCTGCTCCATCCAAAACTGGAAACTATCAATATTCAGTGATTCTCAGATCAGATTCGTTCATGGGACTAGATCAGATCAAGCCACTTAAGCTGGAGGTTCATGAGGCGAAGGCCATGATGGATAACCACCCGCAGTGGGACATCCCAGAaactgaggaagaggaggatgacCAGGAGGACAGTGACGGCATTGAGGAGTCTGAGGAAGACGAAGAAGACAACGACTAAAATCATTTCATGCAAACTTGAGCACAGCTCATACACCCATGTgcccgctcacacacacacacacacacctacacacacagcCCCGGACTTCTGGGCCACCATACACACCAGAAGCAAACAGGAGACAAGGACGTTGACGCCCCATGATCCTGTTTAAAACACTCATGAATCACATTTATTTCGCCAGTCAAACACTCGGTTCTCTTTCCCTGCGTTCATCCAGTCGTTATCAGTGGGCTTTCACCATGGTTATCTGTGGGTTCCAGCTGTGTTTCAGATTCCTCTCCACTTGACGAAAAAGATGCATCGGAATAAATAAAACCAGATTTCCgctttaaaaagagaaaa

Function

symbol description
sec63 Predicted to enable RNA binding activity and protein transmembrane transporter activity. Acts upstream of or within endoplasmic reticulum unfolded protein response; liver development; and myelination. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be part of Sec62/Sec63 complex. Used to study fatty liver disease and polycystic liver disease. Human ortholog(s) of this gene implicated in polycystic liver disease. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator).

GO:

id name namespace
GO:0006614 SRP-dependent cotranslational protein targeting to membrane biological_process
GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane biological_process
GO:0030968 endoplasmic reticulum unfolded protein response biological_process
GO:0042552 myelination biological_process
GO:0001889 liver development biological_process
GO:0031204 posttranslational protein targeting to membrane, translocation biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0031207 Sec62/Sec63 complex cellular_component
GO:0003723 RNA binding molecular_function
GO:0008320 protein transmembrane transporter activity molecular_function

KEGG:

id description
ko03060 Protein export
ko04141 Protein processing in endoplasmic reticulum
ko03110 Chaperones and folding catalysts
ko02044 Secretion system

ZFIN:

id description
ZDB-GENE-040718-328 Predicted to enable RNA binding activity and protein transmembrane transporter activity. Acts upstream of or within endoplasmic reticulum unfolded protein response; liver development; and myelination. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be part of Sec62/Sec63 complex. Used to study fatty liver disease and polycystic liver disease. Human ortholog(s) of this gene implicated in polycystic liver disease. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator).

Ensembl:

ensembl_id ENSDARG00000017740

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034659 False 4207 mRNA 0.42 20 32501748 32521973
TCONS_00034660 False 601 lncRNA 0.40 2 32501763 32506237
TCONS_00034661 True 753 lncRNA 0.46 2 32518209 32520467

Neighbor

gene id symbol gene type direction distance location
XLOC_017435 si:ch73-257c13.2 coding upstream 2456 32497260 ~ 32499292 (+)
XLOC_017434 ostm1 coding upstream 10712 32473584 ~ 32491036 (+)
XLOC_017433 CU138515.1 coding upstream 31294 32466886 ~ 32470454 (+)
XLOC_017432 snx3 coding upstream 68877 32406011 ~ 32432871 (+)
XLOC_017431 BX927123.1 coding upstream 99388 32270907 ~ 32402360 (+)
XLOC_017437 scml4 coding downstream 1603 32523576 ~ 32576703 (+)
XLOC_017438 si:dkeyp-13d11.1 coding downstream 147502 32669475 ~ 32673235 (+)
XLOC_017439 lratd1 coding downstream 234790 32756763 ~ 32758949 (+)
XLOC_017440 NA coding downstream 305447 32827420 ~ 32850103 (+)
XLOC_017441 NA coding downstream 535811 33057784 ~ 33058544 (+)
XLOC_017430 BX842669.1 non-coding upstream 260779 32231609 ~ 32240969 (+)
XLOC_017426 BX927258.1 non-coding upstream 778251 31722252 ~ 31723497 (+)
XLOC_017425 BX511244.1 non-coding upstream 1114577 31387055 ~ 31387171 (+)
XLOC_017455 BX296562.2 non-coding downstream 1437597 33959570 ~ 33975292 (+)
XLOC_017471 BX279523.2 non-coding downstream 2139582 34661555 ~ 34663198 (+)
XLOC_017472 BX279523.3 non-coding downstream 2141349 34663322 ~ 34664762 (+)

Expression


Co-expression Network