XLOC_017721 (thbd)


Basic Information

Item Value
gene id XLOC_017721
gene name thbd
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 51464670 ~ 51476849 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035070
TGGGAAATGTTTTGTCGTCCAGACCGACACCGCGAACTTTGACGCGGCGCAGAAAGTCTGTGAGGAGCGAACAGGACATCTGATGACCATCCGCACCGCAAAACTAGCCGATGTGTTATCTCGGTTATTATTAAAAGGAGAGTCGGGAAACTTCTGGATTGGGCTGAGATATGTCGGTAATGAGTGTTCAGATAGATTAAAGGGATATAAATGGATCACTGGAGATGACACGAGCCACTTTTCCAACTGGAAAAGAGAATCAGATTGTGCGCCAAGTTGTGTTTCGGTATCACAAAACGATCACAAATGGACAGAGAGACCGTGCAGTGACCGAATAGATGgttatgtgtgtgaatataacaatttaaatcaCTGTCCGCCGCTCAGCACTGATGAAAAAGTCCATTATTCGACTGCTTTTGGATTTACATCAAACGAACTCCTCAGAGAGATTCCCGAATTGACTAATGCAACAAGGCTTGATCTTAGGACCAAACACATTTGTTTTGACAGCGAGTGGCTTCATGCGCCCTGGAACTGTGAGGTTTTTGATGGTGGATGTGATTATACGTGTGTTAGGAACGGGCAGAGCTACGCATGCATCTGTCAGCCGGGATTTAAGCTGGACACAAACGGGATATCGTGCAGCCAGCAGCAGGACGATGACCCGTGCGCGCATGCGGGATGCGAACACGAGTGCGCGCGAGATAGCGGTGCGTTCGCGTGCACGTGTCGCCCGGGGTTTACCCTGAGTGCGGACGGAAAGTCTTGCAAAGAGAACTGCAAGCCCGGCTATATCAATGAAAACGGCGGATGCGTTGATGTTGACGAATGCGCAACAGGACCGTGTGAACACGACTGCGCCAACACTGAGGGCAGCTATCAGTGCGTATGTTTTGATGGATACAAACCGGCAGCTAAGGACATGCACAAATGTAAAATGCACTGTCCGGACATGAGATGCAAGGCTGAATGTGATCCCAATAATGATTACCAGTGCGACTGCCCTGATGGTTTCCTATTTGACGAAGATGACAGATATTGCGTTGATGTAGATGAATGCATAAGTACCAATGACTGTGACCAGAATTGTACAAACACACCAGGatcatttgaatgtttttgtcaTGAAGGATACGTGCTTTTGGACAATGGGGTGTGTGAAGACTTGGAGGGTTCAGGCAGCTCAACGCCTTTTGACCTTTTCATTCCCACAAGCAGACCCCCAACCGACCGGCCACTGTCCATTTCTGCGGGCAGTCTTTTGGGAGTAATGGTCTGCGTTGTTGTTTGTGTGCTGCTACTGGTCTGCCTTGCGCACTGCATACTGAGACGACTGAGTAAAACGAACCATTACGATACACATAAAGTCCACGATGAAATCTACGATTTTCAACAGGTG
>TCONS_00035071
ATGAAATCTACGATTTTCAACAGtGCTCACAGAATGGGATATACATTCATACTGATCCTTTTTGGATTGTGCCTGAACACTGAAGTCGTGAAAAGCACCTCCGAGTGTTCAGTTATCGGCTATAATGCCATCTGCATAAACAGAGGTCTTCATCAGGTGCCAGAGCTGCCCGCGCATGTCAATTATGTGGATCTGAGTTTAAACAGCATCGCTGAACTCAACGAAACATCTTTTTCTCGTCTTCAAGATTTACAATTCCTCAAAGTGGAGCAACAAACACCAGGACTCGTGATCAGAAACAACACGTTTAGAGGACTCTCCAGTCTAATAATACTTAAATTAGACTACAACCAATTCCTACAATTAGAGACGGGCGCGTTTAATGGATTAGCAAACCTTGAAGTGCTCACTCTCACGCAGTGTAATTTAGATGGTGCTGTTTTGTCTGGTAACTTCTTCAAACCTCTGACATCTCTTGAGATGCTTGTCTTGCGTgataacaacattaaaaaaatccaGCCAGCTTCATTCTTCCTTAATATGAGGCGATTTCATGTGCTGGATCTGACTTTCAACAAAGTGAAGAGCATCTGTGAGGAAGACCTCCTGAACTTTCAGGGTAAACATTTCACACTCCTCAGACTGTCCTCCATAACACTGCAAGACATGAATGAGTACTGGTTAGGATGGGAGAAATGTGGAAACCCATTTAAGAATACTTCAATAACCACATTGGATCTATCTGGAAACGGCTTTAAAGAGTCAATGGCGAAGCGTTTTTTTGATGCAATCGCTGGTACCAAAATCCAAAGTCTCATTCTCAGTAATAGTTACAATATGGGGAGTTCATTTGGACATACCAATTTTAAGGATCCAGACAATTTTACATTCAAGGGTCTTGAAGCGAGTGGTGTTAAGACTTGTGATTTATCCAAATCAAAAATCTTTGCTCTGCTGAAATCAGTATTTAGTCATTTCACAGACCTAGAACAACTGACCTTGGCGCAAAATGAGATCAACAAGATTGACGATAACGCATTTTGGGGTTTGACACATTTGCTAAAGCTAAACCTGTCCCAAAATTTCCTCGGTAGCATCGATTCGAGAATGTTTGAAAATCTTGACAAACTTGAGGTGCTCGATTTGTCTTATAACCATATAAGGGCTCTTGGAGATCAATCGTTTCTGGGACTCCCAAACTTACGCAAATTAAACTTAACAGGAAACGCTGTGGAGTCAGTCCATACATTTGCTGCCTTACCAAACCTGAACAAACTCTACTTGGGTAAAAACAGAATTTCATCTGTGTCTAGTTTACCCAACATCGCACACAATCTTTCAACACTTGACCTGGAATTTAACAAACTACACGCCTTGTCAGATTTGTACACAATATTACGAGAATTTCCtcaaatagaaaatatatttcttCAAGGTAACACCTTCTCAAGCTGTTATAATCAAAAACAGATAGTGCTTTCAGACAAACTTCAACTCCTCCATCTTGGGCTTTCAAGTATGCAGCTGATCTGGTCAGAAGGAAAATGTTTAAACGTGTTTGCCGATCTTCACCAGTTACAGCAGCTGTCTCTGACCGCCAATGGACTGCAGTCACTTCCCAAAGACATCTTCAAAGACCTTACATCTCTGTTCTTTTTAGATTTGTCTTTCAACTCTTTGAAATACCTTCCCACTGATGTATTCCCCAAAAGTCTTCAAATTCTTAATCTCGACTATAATTCAATTTATTCAGTAGATCCGAATCTCTTCAGCACCCTCAGCTACCTCAGCCTGATGAATAACGATTTCCGATGTGATTGTGACTTGAAGGATTTCCAAACATGGCTAAATCAAACCAACGTAACCTTCGTTCACCCTATTGAGGATGTGACGTGTGCCAGTCCTGAGGATCAGTACATGGTTCCGGTTGTAAAATCCAGTATACAATGTGAGAATGAAGAGGAGGAGAGAAGAACTGAAAAACTAAGACTTGTGCTTTTTATTGTCTGCACTGTATTGATTATATTATTCACCGCCAGCACCATTGTTTACATTAGTCGACGCGGTGTCATCTTTAAGATGTACAAAAAACTAATTGGCGAACTTGTGGATGGAAAGCGTGAGGAGCCTGATCCTGATAGATTTTTGTACGATGTGTACCTGTGTTTCAGTTCTAAAGACATGAAGTGGGTAGAAAGAGCGTTGTTGAAGAGGCTGGACTCTCAGTTTTCAGAGCACAACACACTCCGCTGCTGCTTCGAGGAGCGAGACTTCATCCCCGGGGAGGACCATCTTACCAATATGAGAAGTGCCATCCAGAATAGTCGAAAAACCATTTGCGTGGtgtctgaacacttcctgaaggACGGCTGGTGTCTAGAAACATTCACCCTGGCACAAAAAAGGATGCAAGCAGAGCTTGAGGACATTCTGGTGGTGCTTGTTGTAGGAAACATACCGCAGTACAGGTTACTGAAGTACAAACAAGTGAGATCCTTCATTGAGAACAGAAGTTACCTCGTGTGGCCTGATGACTGTCAAGACTTGGAGTGGTTTTATGACCAACTTCTGCACAAGATAAGAAAAGATATCAAGATTAATCAAACGACCAAAGAAATAAAGCGTGAGGAAGCCAATTTCAACACCAACACAGCAGTATAA
>TCONS_00035072
tgaaaAGAGAGAGGACGAAGGAAGAGCTCATAATCGCCGTAAGGAGCTTAGTAGTTAATTGAACTCTGCGTGGGTCGTCATGTTGCGTTATTGAAACTCCTTATTGTTTTCGCGCCATAACAAGGCTTAGGAAAACGCTGTATGGATAGATGATCCGtGCTCACAGAATGGGATATACATTCATACTGATCCTTTTTGGATTGTGCCTGAACACTGAAGTCGTGAAAAGCACCTCCGAGTGTTCAGTTATCGGCTATAATGCCATCTGCATAAACAGAGGTCTTCATCAGGTGCCAGAGCTGCCCGCGCATGTCAATTATGTGGATCTGAGTTTAAACAGCATCGCTGAACTCAACGAAACATCTTTTTCTCGTCTTCAAGATTTACAATTCCTCAAAGTGGAGCAACAAACACCAGGACTCGTGATCAGAAACAACACGTTTAGAGGACTCTCCAGTCTAATAATACTTAAATTAGACTACAACCAATTCCTACAATTAGAGACGGGCGCGTTTAATGGATTAGCAAACCTTGAAGTGCTCACTCTCACGCAGTGTAATTTAGATGGTGCTGTTTTGTCTGGTAACTTCTTCAAACCTCTGACATCTCTTGAGATGCTTGTCTTGCGTgataacaacattaaaaaaatccaGCCAGCTTCATTCTTCCTTAATATGAGGCGATTTCATGTGCTGGATCTGACTTTCAACAAAGTGAAGAGCATCTGTGAGGAAGACCTCCTGAACTTTCAGGGTAAACATTTCACACTCCTCAGACTGTCCTCCATAACACTGCAAGACATGAATGAGTACTGGTTAGGATGGGAGAAATGTGGAAACCCATTTAAGAATACTTCAATAACCACATTGGATCTATCTGGAAACGGCTTTAAAGAGTCAATGGCGAAGCGTTTTTTTGATGCAATCGCTGGTACCAAAATCCAAAGTCTCATTCTCAGTAATAGTTACAATATGGGGAGTTCATTTGGACATACCAATTTTAAGGATCCAGACAATTTTACATTCAAGGGTCTTGAAGCGAGTGGTGTTAAGACTTGTGATTTATCCAAATCAAAAATCTTTGCTCTGCTGAAATCAGTATTTAGTCATTTCACAGACCTAGAACAACTGACCTTGGCGCAAAATGAGATCAACAAGATTGACGATAACGCATTTTGGGGTTTGACACATTTGCTAAAGCTAAACCTGTCCCAAAATTTCCTCGGTAGCATCGATTCGAGAATGTTTGAAAATCTTGACAAACTTGAGGTGCTCGATTTGTCTTATAACCATATAAGGGCTCTTGGAGATCAATCGTTTCTGGGACTCCCAAACTTACGCAAATTAAACTTAACAGGAAACGCTGTGGAGTCAGTCCATACATTTGCTGCCTTACCAAACCTGAACAAACTCTACTTGGGTAAAAACAGAATTTCATCTGTGTCTAGTTTACCCAACATCGCACACAATCTTTCAACACTTGACCTGGAATTTAACAAACTACACGCCTTGTCAGATTTGTACACAATATTACGAGAATTTCCtcaaatagaaaatatatttcttCAAGGTAACACCTTCTCAAGCTGTTATAATCAAAAACAGATAGTGCTTTCAGACAAACTTCAACTCCTCCATCTTGGGCTTTCAAGTATGCAGCTGATCTGGTCAGAAGGAAAATGTTTAAACGTGTTTGCCGATCTTCACCAGTTACAGCAGCTGTCTCTGACCGCCAATGGACTGCAGTCACTTCCCAAAGACATCTTCAAAGACCTTACATCTCTGTTCTTTTTAGATTTGTCTTTCAACTCTTTGAAATACCTTCCCACTGATGTATTCCCCAAAAGTCTTCAAATTCTTAATCTCGACTATAATTCAATTTATTCAGTAGATCCGAATCTCTTCAGCACCCTCAGCTACCTCAGCCTGATGAATAACGATTTCCGATGTGATTGTGACTTGAAGGATTTCCAAACATGGCTAAATCAAACCAACGTAACCTTCGTTCACCCTATTGAGGATGTGACGTGTGCCAGTCCTGAGGATCAGTACATGGTTCCGGTTGTAAAATCCAGTATACAATGTGAGAATGAAGAGGAGGAGAGAAGAACTGAAAAACTAAGACTTGTGCTTTTTATTGTCTGCACTGTATTGATTATATTATTCACCGCCAGCACCATTGTTTACATTAGTCGACGCGGTGTCATCTTTAAGATGTACAAAAAACTAATTGGCGAACTTGTGGATGGAAAGCGTGAGGAGCCTGATCCTGATAGATTTTTGTACGATGTGTACCTGTGTTTCAGTTCTAAAGACATGAAGTGGGTAGAAAGAGCGTTGTTGAAGAGGCTGGACTCTCAGTTTTCAGAGCACAACACACTCCGCTGCTGCTTCGAGGAGCGAGACTTCATCCCCGGGGAGGACCATCTTACCAATATGAGAAGTGCCATCCAGAATAGTCGAAAAACCATTTGCGTGGtgtctgaacacttcctgaaggACGGCTGGTGTCTAGAAACATTCACCCTGGCACAAAAAAGGATGCAAGCAGAGCTTGAGGACATTCTGGTGGTGCTTGTTGTAGGAAACATACCGCAGTACAGGTTACTGAAGTACAAACAAGTGAGATCCTTCATTGAGAACAGAAGTTACCTCGTGTGGCCTGATGACTGTCAAGACTTGGAGTGGTTTTATGACCAACTTCTGCACAAGATAAGAAAAGATATCAAGATTAATCAAACGACCAAAGAAATAAAGCGTGAGGAAGCCAATTTCAACACCAACACAGCAGTATAATCATGGTAGACTTATTATACATTTAGTATGTTTTTCATTACAGTTTTAGAATTTACCTACACTGTAAACcataatgttgtctttacttaaacaaatcaagtaaagttgactgaacattactaaaaatttagcattttgatCATGTcacctaaaaatacaaattaatttaacttatataccatgaaaatgcataaacttaagatttcaagtatACTAAGCTCAAAATCACAAATAATCCTTTGAAAAATAAGGTTGTTTttaatgtagtcttgactgtaaTTCTAATATGTGCAATTTTTTAATGcaagttctttttttaaattagaaaacaaggctttatgtattattattcacCATAAAAGGAATAAATggttacttatttttcttttaagcatttttttcataGTGTATAATTACACACACAGAACTGATCAATTTAAGTATAATCAAAacagcaagttaaataaacttaaatacgCAAGTTTTGGGAGATTTcgttactcaattaaattgaggcaaagAGCTTACTCAAATAATTTCATTCAGTCAACTTATTATGGTTTTCAGTGTTCTCGAATGAGTGTTTTAAAAGGTTATAATGGAATTTACTACATTACATGTTTGTTTCAAACCCAAACTATTTTCAAACACCTGTGTGATTGTGACCCTGCCAAATAAACTTCCAAATAAGGTCA

Function

symbol description
thbd Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Predicted to be involved in elastic fiber assembly. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin).

GO:

id name namespace
GO:0048251 elastic fiber assembly biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function

KEGG:

id description
ko04610 Complement and coagulation cascades
ko05418 Fluid shear stress and atherosclerosis
ko04933 AGE-RAGE signaling pathway in diabetic complications
ko04090 CD molecules
ko00535 Proteoglycans
ko04091 Lectins

ZFIN:

id description
ZDB-GENE-040219-15 Predicted to enable signaling receptor activity. Involved in toll-like receptor 5 signaling pathway. Acts upstream of or within activation of immune response and toll-like receptor signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in Legionnaires' disease; cystic fibrosis; cystitis; melioidosis; and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).
ZDB-GENE-110411-281 Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Predicted to be involved in elastic fiber assembly. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin).

Ensembl:

ensembl_id ENSDARG00000052322 ENSDARG00000092470

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035070 False 1402 mRNA 0.48 1 51464670 51466071
TCONS_00035071 False 2661 mRNA 0.41 2 51466046 51476154
TCONS_00035072 True 3490 mRNA 0.38 2 51471921 51476849

Neighbor

gene id symbol gene type direction distance location
XLOC_017720 CU660013.1 coding upstream 53491 51407080 ~ 51411179 (+)
XLOC_017719 CU660013.4 coding upstream 73381 51389901 ~ 51391289 (+)
XLOC_017718 tmem151ba coding upstream 130141 51312883 ~ 51334529 (+)
XLOC_017717 hsp90ab1 coding upstream 250841 51197758 ~ 51213829 (+)
XLOC_017716 NA coding upstream 291166 51168912 ~ 51173504 (+)
XLOC_017722 tlr5a coding downstream 2090 51478939 ~ 51482683 (+)
XLOC_017723 CU929372.1 coding downstream 39353 51516202 ~ 51516318 (+)
XLOC_017724 NA coding downstream 170745 51647594 ~ 51667197 (+)
XLOC_017725 aida coding downstream 253809 51730658 ~ 51753885 (+)
XLOC_017726 taf1a coding downstream 336583 51813432 ~ 51874288 (+)
XLOC_017714 AL928824.2 non-coding upstream 308569 51062874 ~ 51156101 (+)
XLOC_017709 NA non-coding upstream 960406 50451469 ~ 50504264 (+)
XLOC_017727 NA non-coding downstream 458454 51935303 ~ 52061098 (+)
XLOC_017728 CU179729.1 non-coding downstream 587178 52064027 ~ 52082500 (+)
XLOC_017729 NA non-coding downstream 615736 52092585 ~ 52235440 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000029_07503905_07506541 TLR5B coding CI01000029 null 7503905 ~ 7506835 (+)